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All Journal Journal of Food and Pharmaceutical Science Jurnal Ilmiah Farmasi Indonesian Journal of Pharmaceutical Science and Technology Pharmascience Jurnal Surya Medika SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian Al-Ikhlas Pharmacoscript Borneo Journal Of Pharmascientech Lombok Journal of Science Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi SYIFA Journal of Food and Pharmaceutical Sciences Jurnal Farmasi dan Farmakoinformatika GEMASSIKA: Jurnal Pengabdian kepada Masyarakat Borneo Journal of Pharmacy Pharmacon: Jurnal Farmasi Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Saputri, Revita
Fakultas Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Uji Aktivitas Antioksidan Ekstrak Etanol Buah dan Biji Buah Kalangkala (Litsea angulata) asal Kalimantan Selatan: Antioxidant Activity Test of Ethanolic Extract of Kalangkala (Litsea angulata) Fruits and Seeds from South Kalimantan Revita Saputri; Eka Fitri Susiani
Borneo Journal of Pharmacy Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i2.370

Abstract

Free radicals are atoms or molecules, having one or more unpaired electrons. Increased production of free radicals can cause oxidative stress and cause many pathological conditions, e.g. cancers, heart diseases, and other diseases. The antioxidant can inhibit oxidative stress. Kalangkala (Litsea angulata) usually found in the South Kalimantan that can be used as an antioxidant. The study aimed to determine the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds from South Kalimantan. Antioxidant activity was conducted qualitatively and quantitative uses the method DPPH. The result of the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds qualitatively showed the presence of yellow spots on a purple background at Thin Layer Chromatography (TLC). The result of the activity of ethanolic extract of Kalangkala seeds quantitatively obtained IC50 value was 48.78 ppm and activity of ethanolic extract of Kalangkala fruits quantitatively obtained IC50 value was 243.14 ppm. Ethanolic extract of Kalangkala fruits and seeds from South Kalimantan has antioxidant activity.
Antioxidant Activity of Ethanolic Extract from Tandui Leaves (Mangifera rufocostata Kosterm.) by DPPH Radical Scavenging Method Revita Saputri; Tia Mariati Risma Melati; Fitriyanti Fitriyanti
Borneo Journal of Pharmacy Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i2.1070

Abstract

Tandui (Mangifera rufocostata Kosterm.) is a typical plant from South Kalimantan which belongs to the genus of Mangifera. Several species of Mangifera are known to have antioxidant activity. This study aimed to determine the antioxidant activity of ethanol extract of Tandui leaves. Tandui leaves that were obtained from the maceration method used 70% ethanol. Antioxidant activity was conducted quantitative using the DPPH (2,2-diphenyl-1-picrylhydrazil) method. The result of the antioxidant activity of Ethanol extract of Tandui leaves quantitatively obtained IC50 value was 60.7042 µg/mL. The ethanol extract of Tandui leaves has strong antioxidant activity
Aktivitas Antioksidan Ekstrak Metanol Daun Tandui (Mangifera rufocostata K.)Menggunakan Metode DPPH Eka Fitri Susiani; Revita Saputri; Helmina Wati; Fitria Mahmudah; Vebruati Vebruati
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.477

Abstract

Free radicals are highly reactive compounds because they have unpaired electrons so that they can interact with body cell molecules, this can cause various diseases. Antioxidants are compounds that can ward off free radicals. Plants of the genus Mangifera are known to have antioxidant activity, one of which is Mangifera rufocostata Kosterm, a typical plant of South Kalimantan known as tandui. The purpose of this study was to determine the antioxidant activity of the methanol extract of the leaves of tandui (Mangifera rufocostata Kosterm.) using the DPPH test method. Phytochemical screening and antioxidant activity tests were performed using a UV-Vis spectrophotometer. The compounds contained in the methanol extract of tandui leaves (Mangifera rufocostata Kosterm.) are phenols, flavonoids, and tannins. The IC50 value of quercetin obtained was 2.39 ppm and the IC50 value of the tandui leaf methanol extract (Mangifera rufocostata Kosterm.) which was obtained was 8.222 ppm. Tandui leaf methanol extract has very strong antioxidant activity.
Uji Aktivitas Antioksidan Ekstrak Etil Asetat Daun Tigaron (Crateva Religiosa) Menggunakan Metode DPPH Rosya Rizky Maulidya; Revita Saputri; Liana Fitriani Hasymi
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 2 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i2.488

Abstract

Tigaron leaf methanol extract (Crateva religiosa) was reported to have activity as a very strong antioxidant. Differences in solvents in extracts can affect the results of pharmacological activity, for example, ethyl acetate solvent on antioxidant activity, so the purpose of this study was to determine the results of phytochemical screening and antioxidant activity of the ethyl acetate extract of Tigaron leaves (Crateva religiosa). Phytochemical screening was carried out qualitatively, while antioxidant activity was carried out quantitatively using the DPPH (2,2-Diphenyl-1-picrylhydrazyl) method using a UV-Vis spectrophotometer and quercetin comparator. The ethyl acetate extract of Tigaron leaves (Crateva religiosa) was extracted by maceration method. Phytochemical screening tests obtained positive results for the alkaloids, flavonoids, and steroids. Antioxidant testing using the comparator quercetin obtained IC50 results of 3.4384 ppm and the ethyl acetate extract of Tigaron (Crateva religiosa) leaves obtained IC50 results of 114.0457 ppm. It can be concluded that the ethyl acetate extract of Tigaron leaves (Crateva religiosa) has moderate potential as an antioxidant.
Penetapan Kadar Flavonoid Total Ekstrak Etanol 70% Daun Bayam Brazil (Althernanthera sisso) Dengan Metode Spektrofotometri UV-Vis Nur Humaira Marwati; Revita Saputri; Eka Fitri Susiani
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.496

Abstract

Brazilian Spinach (Althernanthera sisso) leaves are known to have a high natural antioxidant activity content of 3.7 ppm. Antioxidants have an important role in the human body to prevent damage caused by free radicals. One of the compounds that have antioxidant activity is flavonoids. Based on this description, it is necessary to know the content of total flavonoids in A. sisso This study aims to determine qualitatively using Thin Layer Chromatography (TLC), while quantitatively using UV-Vis spectrophotometry. Maceration method with 70% ethanol solvent was used to extract Brazilian spinach leaves. Thin Layer Chromatography (TLC) followed by spray reagents was used to test the flavonoid compounds. Quercetin reagent was used to determine total flavonoid levels, while AlCl3 was used to determine total flavonoid levels. The results of this qualitative test showed the presence of flavonoids, and in the quantitative test using UV-Vis spectrophotometry the total levels of flavonoids were 70.890 ± 1.723% w/w quercetin equivalent. The 70% ethanol extract of A. sisso leaves contains flavonoids so that it has the potential to be developed as a medicinal plant
PENGARUH METODE EKSTRAKSI TERHADAP AKTIVITAS ANTIBAKTERI DAUN RAMANIA (Bouea macrophylla Griffith) TERHADAP Staphylococcus aureus Fitriyanti; Syifa; Ahmad; Revita Saputri; Rahmi Muthia
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1462

Abstract

Ekstrak metanol dari daun Ramania (Bouea macrophylla Griffith) telah teruji dengan dosis kecil memiliki efek antibakteri terhadap bakteri Staphylococcus aureus, namun belum pernah dilakukan pengujian pada dosis yang lebih tinggi dan membandingkan pada metode ekstraksi yang berbeda seperti maserasi dan soxhletasi. Pada penelitian bermaksud untuk mengetahui golongan senyawa yang terdapat pada ekstrak metanol dari daun ramania dengan metode yang berbeda dan untuk mengetahui pengaruh peningkatan konsentrasi ekstrak terhadap penghambatan bakteri S.aureus dengan penyarian secara maserasi dan soxhletasi. Uji antibakteri dilakukan menggunakan metode difusi sumuran. Penapisan fitokimia terhadap ektrak metanol daun remania menunjukkan keberadaan senyawa yaitu mengandung senyawa saponin, flavonoid, fenol, tanin, steroid. Hasil ují antibakteri terhadap ekstrak daun ramania yang diperoleh dengan metode maserasi lebih baik dibandingkan dengan ekstrak yang diperoleh dengan metode Soxlet, yaitu pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 19,28;13,28; 12,93; 12,25; dan 10,98 mm, dengan kategori kuat. Sedangkan hasil pada pengujian dengan esktraksi menggunakan alat soxhlet pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 10,7; 10,3; 8,9; 8,6; dan  8,3 mm dengan kategori sedang sampai kuat.
Uji Aktivitas Antioksidan Ekstrak Etanol 96% Daun Tigaron (Crateva religiosa G.Forst.) Asal Kalimantan Selatan Menggunakan Metode DPPH Sari, Rika Amara Widya; Saputri, Revita; Khairunnisa, Khairunnisa
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 2 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i2.495

Abstract

Ethanol extract leaves of Crateva religiosa G.Forst. has antioxidant activity using the FRAF method of 357.9 ± 17.6 μmol/L., but the antioxidant activity of the 96% ethanol extract of C. religiosa G.Forst leaves. from South Kalimantan has not been reported. This study aims to determine the secondary metabolites and antioxidant activity of the 96% ethanol extract of Tigaron (C. religiosa G.Forst.) leaves from South Kalimantan using the DPPH method measured with a UV-Vis spectrophotometer. Tigaron (C. religiosa G.Forst.) leaves 96% ethanol extract was prepared by maceration method. Tigaron (C. religiosa G.Forst.) leaves antioxidant activity test was carried out at concentrations of 50 ppm, 75 ppm, 100 ppm, 125 ppm and 150 ppm using quercetin as a comparison. Phenol, flavonoid, quinone, and tannin were all detected in the phytochemical screening. Testing the antioxidant activity of the quercetin comparator showed an IC50 of 3.0151 (very strong) and the 96% ethanol extract of tigaron (C. religiosa G.Forst.) leaves showed an IC50 of 94.9082 ppm (strong). Based on the results obtained that the 96% ethanol extract of tigaron (C. religiosa G.Forst.) leaves from South Kalimantan has antioxidant activity in the strong category.
PENGARUH METODE EKSTRAKSI TERHADAP AKTIVITAS ANTIBAKTERI DAUN RAMANIA (Bouea macrophylla Griffith) TERHADAP Staphylococcus aureus Fitriyanti; Syifa; Ahmad; Revita Saputri; Rahmi Muthia
Pharmacoscript Vol. 7 No. 1 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i1.1462

Abstract

Ekstrak metanol dari daun Ramania (Bouea macrophylla Griffith) telah teruji dengan dosis kecil memiliki efek antibakteri terhadap bakteri Staphylococcus aureus, namun belum pernah dilakukan pengujian pada dosis yang lebih tinggi dan membandingkan pada metode ekstraksi yang berbeda seperti maserasi dan soxhletasi. Pada penelitian bermaksud untuk mengetahui golongan senyawa yang terdapat pada ekstrak metanol dari daun ramania dengan metode yang berbeda dan untuk mengetahui pengaruh peningkatan konsentrasi ekstrak terhadap penghambatan bakteri S.aureus dengan penyarian secara maserasi dan soxhletasi. Uji antibakteri dilakukan menggunakan metode difusi sumuran. Penapisan fitokimia terhadap ektrak metanol daun remania menunjukkan keberadaan senyawa yaitu mengandung senyawa saponin, flavonoid, fenol, tanin, steroid. Hasil ují antibakteri terhadap ekstrak daun ramania yang diperoleh dengan metode maserasi lebih baik dibandingkan dengan ekstrak yang diperoleh dengan metode Soxlet, yaitu pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 19,28;13,28; 12,93; 12,25; dan 10,98 mm, dengan kategori kuat. Sedangkan hasil pada pengujian dengan esktraksi menggunakan alat soxhlet pada konsentrasi 50, 40, 30, 20 dan 10%, memberikan zona hambat berturut-turut sebesar 10,7; 10,3; 8,9; 8,6; dan  8,3 mm dengan kategori sedang sampai kuat.
PENETAPAN KADAR TOTAL FENOLIK-FLAVONOID EKSTRAK ETANOL 70% KULIT BATANG TANDUI (Mangifera rufocostata Kosterm.) Eka Fitri Susiani; Revita Saputri; Allisa Fanadia; Liana Fitriani Hasymi
Jurnal Ilmiah Manuntung Vol 9 No 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.676

Abstract

Tandui (Mangifera rufocostata Kosterm.) is a species of the genus Mangifera which is known to contain phenolic and flavonoid compounds and is one of the plants used as an alternative medicine by the people of South Kalimantan. The purpose of this study was to determine the total phenolic and flavonoid content of 70% ethanol extract of tandui bark. Qualitative analysis using phenolic and flavonoid phytochemical screening with 3% FeCl3, Mg-HCl reagents and Thin Layer Chromatography (TLC) with spot appearance 10% FeCl3 for phenolic and 5% AlCl3 for flavonoid compounds. Quantitative analysis using UV-Vis spectrophotometry, determination of total phenolic content using Folin-Ciocalteu reagent with gallic acid standard solution, while determination of total flavonoid content using AlCl3 reagent with quercetin standard solution. The results of identification of phenolic and flavonoid compounds by phytochemical screening and TLC showed that 70% ethanol extract of tandui bark contained phenolic and flavonoid. The results of the determination of the total phenolic content using UV-Vis spectrophotometry were 471.3126 mgGAE/g or 47.1312%, while the total flavonoid content was 872.075 mgQE/g extract or 87.2075%. Based on these results, it can be concluded that 70% ethanol extract of tandui bark contains secondary metabolites in the form of phenolics and flavonoids which have potential as medicine.
In Vitro Cholesterol Reduction Activity Test Of 70% Ethanol Extract of Hiyung Cayenne Pepper Fruit (Capsicum frutescens L. var hiyung) Originating from Tapin South Kalimantan Mu'mina Hayati; Rizaldi, Gusti; Saputri, Revita
Pharmacon: Jurnal Farmasi Indonesia Volume 22, No 1 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i1.7025

Abstract

Kalimantan Island has an endemic plants that holds potential as a medical one of them namely hiyung cayenne pepper fruit (Capsicum frutescens L. var hiyung) the local commodity of Tapin, South Kalimantan and known as the hottest pepper in Indonesia. It containts secondary metabolites and capsaicin that has potential to lower cholesterol. This study aims to identify secondary metabolite compounds and cholesterol-lowering activity of 70% ethanol extract of hiyung cayenne pepper fruit. Cholesterol lowering test was conducted in vitro by cholesterol complex formation method with FeCl3 using UV-Vis Spectrophotometer at maximum wavelength of 525 nm. The results of the phytochemical screening test showed positively contained alkaloids, triterpenoids, phenols, saponins, tannins and flavonoids. The result of cholesterol reduction test from concentrations of 20, 40, 60, 80, and 100 µg/mL were 53.62%, 58.30%; 64.19%; 70.02%; and 74.91%, respectively. So, the 70% ethanol extract of hiyung cayenne pepper fruit has the potential to reduce cholesterol with the lowest concentration being able to reduce cholesterol by more than 50%.
Co-Authors Abdul Rohman Abdurahman Abdurrahman Ahmad Ahmad Akbar, Depy Oktapian Allisa Fanadia Aristha N. Putri Astuti, Karunita Ika Azmi Yunarti Dyera Forestryana Dyera Forestryana Dyera Forestryana Eka Fitri Susiani Eka Fitri Susiani Eka Fitri Susiani Endang Lukitaningsih Evi Mintowati Kuntorini Fitria Mahmudah Fitriyanti Fitriyanti, Fitriyanti Hafiz Ramadhan Hafiz Ramadhan Helmina Wati Ika P. Sari Indah Widya Lestari Khairunnisa Khairunnisa Liana Fitriani Hasymi Lisa Andina Lisa Setia Maria Dewi Astuti Monalissa Indriani Mu'mina Hayati Muhammad Nazhir Nopita Nur Humaira Marwati Nurul Asfia Prihandini, Yustin Ari Putri Indah Sayakti Rahmatullah, Satrio Wibowo Rahmayanti Fitriah Rahmi Muthia Ratna Restapaty Reny Marliadi Risti Hadiyanti Rizaldi, Gusti Rosya Rizky Maulidya Saputri, Novia Misfa Sari, Rika Amara Widya Selfira Hidayah Souva Asvia Sulastri Azistina Verawati Susiani, Eka Fitri Syifa Syifa Teuku N.S. Sulaiman Tia Mariati Risma Melati Vebruati Vebruati Widyanto, Rinto Yuliana Yuliana