Claim Missing Document
Check
Articles

Kajian Potensi Tumbuhan Nangka (Artocarpus heterophyllus Lam.) dalam Pengobatan Penyakit Infeksi Helen Anjelina Simanjuntak; Nurbaiti Br. Singarimbun; Defacto Firmawati Zega; Suharni Pintamas Sinaga; Herlina Simanjuntak; Toberni S Situmorang
Herbal Medicine Journal Vol 5 No 1 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (410.294 KB) | DOI: 10.58996/hmj.v5i1.36

Abstract

Infectious diseases are one of the health problems because they cause new infectious diseases caused by antibiotic resistance. So it is necessary to search for new antibiotic agents that are sourced from natural ingredients such as jackfruit plants. Jackfruit plant (Artocarpus heterophyllus Lam.) has many benefits ranging from roots, stems, leaves, fruits and seeds. Jackfruit plant has pharmacological properties as anti-inflammatory, antioxidant, antimalarial, antifungal activity, cytotoxic, tyrosinase inhibitory activity and antimicrobial. The purpose of this study was to determine the study of jackfruit plants that have potential as antimicrobials. The research method was carried out using a literature review with online media based on the Web, Scopus, PubMed, Science Direct, ResearchGate, Google Scholar used for publication. The results showed that jackfruit has antimicrobial activity due to the content of bioactive compounds such as: tannins, flavonoids, catechins, artocarpin and artocarpanone. Jackfruit plant parts that have the potential as antimicrobials are the leaves, jackfruit skin, seeds and roots. Jackfruit plants have potential as antimicrobials against Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Propionibacterium acnes, Klebsiella pneumonia, Pseudomonas aeruginosa, Streptococcus mutans, Mycobacterium tuberculosis, Plasmodium falciparum, and Vibrio cholera.
Diameter Zona Hambat Antibiotik Amoxicillin dan Tetracycline terhadap Escherichia coli Helen Anjelina Simanjuntak; Herlina Simanjuntak; Siti Maimunah; Rahmiati Rahmiati; Toberni S Situmorang
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (355.685 KB) | DOI: 10.58996/hmj.v5i2.52

Abstract

Antibiotics are drugs used for infections caused by bacteria. Amoxicillin and tertacycline are antibiotics used to inhibit the growth of Escherichia coli. Escherichia coli bacteria can cause urinary tract infections, diarrhea, gastroenteritis, pneumonia, septicemia, and meningitis. The purpose of this study was to determine the diameter of the inhibition zone of amoxicillin and tetracycline antibiotics in inhibiting Escherichia coli bacteria. Experimental research method with antibacterial activity test using paper disc diffusion method. The results showed that amoxicillin and tetracycline antibiotics had inhibition zone diameters of 18.4 mm and 35.76 mm, respectively, with strong and very strong categories. The conclusion of this study is that tetracycline antibiotics are better at inhibiting the growth of Escherichia coli bacteria than amoxicillin.
Uji Aktivitas Antifungi Sediaan Sampo Ekstrak Etanol Bawang Merah (Allium cepa L.) Terhadap Pityrosporum ovale Rahmiati Rahmiati; Megawati Butar-butar; Helen Anjelina Simanjuntak
Herbal Medicine Journal Vol 4 No 1 (2021): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (384.474 KB) | DOI: 10.58996/hmj.v4i1.67

Abstract

Onion which is a species Alium cepa L. is the name of the plant of the family Lilliaceae. This research was conducted to get antidandruff shampoo of extract ethanol onion (Allium cepa L.) that has the best antifungal activity. This research method used an experimental method. The result of this study prove that the etanol extract of onion (Allium cepa L.) can be formulated as antidandruff shampoo that meets the requirements according to standard of Indonesian National Standard (SNI). The results of antifungal activity test showed that shampoo with a concentration of 5% with a diameter of 34.25 mm had the best antifungal activity followed by 2,5% shampoo with a diameter of 30,5 mm and a shampoo concentration of 1% with a diameter of 27,25 mm to inhibit the growth of Pityrosporum fungi ovale. Data analysis of antifungal test result was done by One Way Anova statistical test. The results showed that there were significant differences between the antidandruff shampoo onion (Allium cepa L.) extract 1%, 2,5%, and 5% concentration.
Aktivitas Antibakteri Ekstrak Etanol Kulit Jeruk Nipis (Citrus aurantifolia (Christm) Swingle) Terhadap Staphylococcus aureus Apri Yoci Ro Berlina; Nora Yanti Lumbangaol; Helen Anjelina Simanjuntak
Herbal Medicine Journal Vol 6 No 1 (2023): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v6i1.77

Abstract

The use of herbal plants is currently being developed as traditional medicine. About 80% of the world's population still relies on natural medicines for their health needs. Especially in the treatment of infectious diseases caused by Staphylococcus aureus bacteria. Treatment can use natural ingredients such as lime peel waste. Lime peel has a higher concentration of flavonoids compared to other parts such as seeds, fruit, and lime juice, making lime peel has antibacterial power. The purpose of this study was to determine the effect of ethanolic extract of lime peel (Citrus aurantifolia (Christm.) Swingle) on the growth of Staphylococcus aureus bacteria and to determine the potential of ethanolic extract of lime peel (Citrus aurantifolia (Christm.) Swingle) as an antibacterial. The extraction method is by maceration using 96% ethanol solvent, while the antibacterial activity test is using the paper disc diffusion method. The results showed that the ethanolic extract of lime peel at concentrations of 10%, 30%, 50% and 70% had inhibition zone diameters of 7.31 mm, 7.67 mm, 9.00 mm and 12.63 mm, respectively. The conclusion of this study is that the ethanolic extract of lime peel is effective at a concentration of 70% with a strong category.
Edukasi Pentingnya Pemberian Imunisasi Dasar Pada Bayi di Desa Namobintang Kabupaten Deli Serdang Helen Anjelina Simanjuntak; Nurbaiti Br. Singarimbun; Junita Br. Manullang; Susi Amenta Br. Perangin Angin; Selli M Pasaribu
Jurnal Pengabdian Masyarakat Bangsa Vol. 1 No. 6 (2023): Agustus
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v1i6.251

Abstract

Imunisasi dasar diwajibkan pada bayi usia 0-9 bulan yaitu BCG, Campak, DPT, Hepatitis B dan Polio. Tujuan kegiatan adalah memberikan edukasi kepada ibu-ibu yang memiliki balita (usia 0-9 bulan) tentang pentingnya pemberian imunisasi. Metode kegiatan berupa penyuluhan yang dilaksanakan di balai Desa Namobintang. Terdata 34 bayi usia 0-9 bulan namun hanya 20 bayi yang memiliki catatan imunisasi. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan peserta terutama para Ibu tentang manfaat imunisasi dasar lengkap, pengetahuan imunisasi dapat dilakukan di posyandu, puskesmas, rumah sakit, bidan praktik, dokter, serta peserta mampu memahami frekuensi dan waktu imunisasi
Potensi Buah Andaliman (Zanthoxylum acanthopodium DC.) sebagai Antibakteri Terhadap Salmonella typhi Helen Anjelina Simanjuntak; Hermawan Purba; Cander Pasaribu; Junius Gian Ginting; Rahmiati Rahmiati; Toberni S Situmorang
Journal of Natural Sciences Vol 4, No 2 (2023): Journal of Natural Sciences Juli
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v4i2.404

Abstract

Typhoid fever is a major disease of death in the medical field caused by Salmonella typhi infection with symptoms including fever, mucosal lesions, vomiting, diarrhea, fluid loss, septicemia, and peritonitis. The use of natural plants to cure infectious diseases such as andaliman fruit. The aim of this study was to determine the antibacterial activity of Andaliman fruit extract on the growth of Salmonella typhi. Experimental research method. The Kirby-bauer method was used for the antibacterial test, the maceration method was used for extraction. The results of phytochemical compounds found flavonoids, tanins, saponins, tannins, alkaloids steroids, and triterpenoids in simplicia and andaliman fruit extracts. All extracts have the potential to inhibit the growth of Salmonella typhi, with the diameter of the inhibition zone consisting of 10.04 mm, 12.22 mm, 15.46 mm and 16.68 mm in the strong category. These doses are 10%, 30%, 50%, and 70%. The analysis shows the potential of Andaliman fruit extract as an antibiotic in the treatment of typhoid fever.
Analisis Cemaran Eschericia coli pada Minuman Cendol yang Dijual di Komplek MMTC dan Sekitarnya Toberni S Situmorang; Rahmiati Rahmiati; Helen Anjelina Simanjuntak
Journal of Natural Sciences Vol 4, No 2 (2023): Journal of Natural Sciences Juli
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v4i2.406

Abstract

Eschericia coli bacteria are fecal coliform bacteria that belong to the Enterobacteriaceae group. This bacterium is an indicator of water quality to test for fecal contamination in a water sample. Cendol is a drink that has many fans because of its sweet and savory taste. The high consumption of cendol in the community is the basis for this drink to maintain its quality. One of the qualities that must be considered is the microbiological quality. The research was carried out in a quantitative descriptive manner and the research data will be displayed in the form of data tabulations. There were 3 samples of cendol tested namely TS1, TS2 and TS3. There were 3 stages in conducting the research, namely sample preparation, counting of total bacteria and testing of Eschericia coli bacteria on selective eosin methylene blue agar (EMBA) media. The results of the analysis showed that the total number of bacteria in the cendol samples tested on samples TS1, TS2 and TS3 were 1.2 x 104 colonies respectively; 4.8 x 104 colonies and 6.6 x 104 colonies. The results of the analysis of E. coli bacteria in the three samples showed that the three samples showed the growth of E. coli bacteria in the test medium. Colonies of E. coli bacteria on EMBA media are marked by the growth of metallic green colonies
OPTIMALISASI MANFAAT MINYAK KARO DI DESA TANGKAHAN Helen Anjelina Simanjuntak; Hermawan Purba; Defacto Firmawati Zega; Junius Gian Ginting
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 4 (2023): Volume 4 Nomor 4 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i4.20427

Abstract

Minyak karo merupakan produk minyak olahan yang dihasilkan oleh masyarakat suku karo yang telah diwariskan secara turun-temurun. Minyak karo berbahan herbal yang digunakan oleh masyarakat suku karo terutama dalam menjaga kesehatan dan pengobatan terutama dalam mengobati masuk angin, pegal linu, terkilir, pergeseran sendi, asam lambung, sakit kepala, alergi, mengobati luka, gatal-gatal dan disengat hewan berbisa. Desa Tangkahan merupakan salah satu desa dengan mayoritas dihuni oleh masyarakat suku karo dengan pekerjaan utama sebagai petani. Beberapa diantara memiliki potensi sebagai pengobat/peracik minyak karo, akan tetapi tidak dikembangkan secara optimal. Kegiatan bertujuan untuk memberikan informasi kepada masyarakat tentang manfaat minyak karo serta cara mengoptimalkannya. Metode kegiatan berupa seminar dan sosialisasi kepada masyarakat tentang manfaat minyak karo serta cara mengoptimalkannya melalui aspek kesehatan, dan aspek pengolahan. Kegiatan dihadiri oleh 40 peserta. Hasil kegiatan menunjukkan adanya antusias dari masyarakat tentang optimalisasi minyak karo melalui pendekatan aspek manfaat dalam kesehatan serta aspek pengolahan yang optimal.
Optimation of Green Synthesis Biopolymer Cellulose Using Acetobacter xylinum From Whey as Media of Bacteria Suharni Sinaga; Junius Gian Ginting; Helen Anjelina Simanjuntak; Dame Meldaria sipahutar; Defacto Firmawai Zega; Yanti Yanti; Sahat Sinaga; Lydia Barus; Hermawan Purba
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS (JPBN) Vol 9, No 3 (2023): Jurnal Pembelajaran Dan Biologi Nukleus November 2023
Publisher : Fakultas Keguruan dan Ilmu Pendidikan Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v9i3.5067

Abstract

Utilizing waste into a more valuable commodity was one of the objectives of that research. Waste which initially became an environmental pollutant factor could be processed into more useful products. Tofu liquid waste was referred to whey was a by-product of tofu production. Whey was waste that still contains organic materials such as protein, fat, carbohydrates and minerals. That whey was used as a growth medium for Acetobacter xylinum bacteria and produces cellulose biopolymer as a result of carbohydrate fermentation. The process of optimizing carbohydrate fermentation by Acetobacter xylinum bacteria was carried out by varying the ratio of the amount of whey to coconut water, the acidity level of the media, and the fermentation time. The research results showed that the biosynthesis of cellulose biopolymer was obtained from a ratio of whey concentration to coconut water of 1:1, variations in acidity levels showed that the optimum fermentation conditions occurred at pH 4, and the optimal amount of cellulose biopolymer was obtained on day 21, namely with the highest percent yield value. The resulting biocellulose was characterized using FTIR, XRD, and SEM. The characterization results show that biocellulose is well formed with a fiber surface shape and particle size in the range of 50-200 nm
The KEMAMPUAN BAKTERI ASAM LAKTAT DALAM MENGHAMBAT Salmonella thypii Rahmiati, Rahmiati; Anjelina Simanjuntak, Helen
Jurnal Jeumpa Vol 6 No 2 (2019): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jj.v6i2.1898

Abstract

Bakteri asam laktat diketahui memiliki kemampuan menghasilkan senyawa antimikroba yang dikenal sebagai bakteriosin. Bakteriosin diketahui memiliki kemampuan bakteriosidal dan bakteriostatik yaitu kemampuan untuk membunuh dan menghambat pertumbuhan mikroorganisme lain. Bakteri asam laktat tersebar luas di alam diantaranya di dalam produk fermentasi dan saluran pencernaan hewan. Penelitian ini difokuskan unutuk melihat kemamouan bakteri asam laktat dalam menghambat pertumbuhan bakteri Salmonella thypii. Pada penelitian ini, bakteri asam laktat yang digunakan merupakan koleksi Laboratorium Biologi Universitas Medan Area. Delapan jenis isolat bakteri asam laktat yang digunakan antara lain IN01, IN02, SF01, SF02, NN01, NN02 SPU01 dan SPU04. Dilakukan uji konfirmasi terhadap pertumbuhan bakteri asam laktat dan Salmonella thypii dengan melakukan konfrmasi secara visual dan mikrokopis melalui pewarnaan diferensial. Keseluruhan bakteri asam laktat merupakan kelompok bakteri gram positif berbentuk basil. Kemampuan hidup isolat bakteri asam laktat pada media dengan variasi pH dan kadar garam ditandai dengan jumlah total koloni yang tumbuh setelah masa inkubasi. Kemampuan antagonis bakteri asam laktat dalam menghambat bakteri patogen ditunjukkan dengan adanya zona hambat yang terbentuk berupa daerah jernih di sekitar koloni patogen. Isolat bakteri SPU01 dan SF01 diketahui memiliki nilai zona hambat terbesar yaitu 29,79 mm dan 28,13 mm.
Co-Authors Amanzino, Regina Asmara Amila Amila, Amila Apri Yoci Ro Berlina Br. Gultom, Sesilia Sri Susandri Br. Manurung, Wulan Anggreni Br. Sembiring, Heylen Sebryna Cander Pasaribu Daeli, Mestika Clemesiya Yulianti Dame Meldaria sipahutar Defacto Firmawai Zega Defacto Firmawati Zega Elseria Saragih Fadilla, Zahira Fransiska Riati Nova Simbolon Ginting, Junius Gian Hayati, Rahmi Herlina Simanjuntak Herlina Simanjuntak Iksen, Iksen Junita Br Manullang Junita Br. Manullang Karnina, Sisca Kasih, Indah Kasmara, Dwi Pratiwi Kasta Gurning Kembaren, Gita Br. Lydia Br Barus Manihuruk, Fani Nuryana Megawati Butar - Butar Megawati Butar-butar Nahampun, Laura Yunita Nora Yanti Lumbangaol Pasaribu, Selli M Pasaribu, Sudana Fatahillah PURBA, FRANSISKA Purba, Hermawan Purba, Sanna Kamisna Royani Purwandari, Vivi Putri, Riska Amelia Rahmiati Rahmiati Rahmiati Rahmiati Ratna A.K Marpaung, Dwi RINI FEBRIANTI Risanti Situmorang Royani Purba, Sanna Kamisna Sahat Sinaga Sahat Sinaga Sapitri, Alfi Sari, Mesi Puspita Selli M Pasaribu Sembiring, Mahral Effendi Sianturi, Ayu Enjelina Sihotang, Santyria Silaban, Elya Cytra Bonaparti Simanjuntak, Herlina Sinaga, Florenita Sinaga, Fnesia Sinaga, Sahat Sinaga, Suharni Pintamas Sinaga, Verawati Br. Singarimbun, Nurbaiti Br Sitanggang, Ketrin Evelia Pinondang Siti Maimunah Siti Maimunah Situmorang, Toberni S. Suharni Sinaga Susi Amenta Br. Perangin Angin Toberni S Situmorang Toberni S Situmorang Toberni S Situmorang Toberni S Situmorang Toberni S Situmorang Toberni S Situmorang Toberni S. Situmorang Wahyuni, Sri Wan Yuli Anjani Wanda Lestari, Wanda Yanti Yanti Yanti Yanti Yelni, Afrida Yusman, Reni Zega, Defcato Firmawati Zega, Ningsih Prastika Zuhairiah Nasution, Zuhairiah