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Journal : Journal of Global Pharma Technology

A Brief Review of Probiotic: Action Mechanism, Benefits, and Clinical Application on Human Health Dewa Ayu Agus Sri Laksemi; I Ketut Tunas; Ni Luh Putu Eka Diarthini
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
Publisher : Journal of Global Pharma Technology

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Abstract

Probiotics are live microorganisms that are commonly used as food supplementation to provide a positive impact on human health. There was an increasing number of studies concerned with the benefit of probiotics due to the enhance community awareness of health. The primarily role of probiotics are known strengthening the epithelial barrier, increasing attachment to the intestinal mucosa, inhibiting the attachment of pathogenic bacteria, competitive exclusion of pathogenic microorganisms, producing anti-microbial substances and thereby modulating host immunity by initiating specific genes activation in the host intestinal tract system. The benefits of probiotics are not only limited to the gastrointestinal system but the mechanism of action includes other organs such as respiratory, urogenital, endocrine, and immune system. Hence, this review study will focus mainly on three aspects such as benefits, action mechanism, and its clinical application of probiotics on human health.Keywords: Action mechanism, Benefits, Clinical application, Probiotics.
Co-Authors ., Ni Putu Ayu Laksmini Anak A. A. W. P. Dewi Budiana, Nyoman Damayanti, Cokorda Istri Dewa Ayu Agus Sri Laksemi Dewa Ayu Agus Sri Laksmi Dewi Puspita Apsari Dewi, Anak A. A. W. P. Dewi, Ni Ketut Cintya Dhiancinantyan Windydaca Brata Putri Farmani, Putu Ika Karma Gayatri, Ni Kadek Weni Diah I Gusti Kamasan Arijana I Gusti NAWW Putra I Kadek Swastika I Ketut Suwiyoga I Made Sudarmaja I Made Sudarmaja I Nyoman Gede Budiana I Nyoman Mahayasa Adiputra I Nyoman Mangku Karmaya I Putu Darma Wijaya I Putu Prisa Jaya . I Putu Riska Ardinata I. Lesmana Ida Ayu Dewi Wiryantini Intan Puspa Kurniastuti, A.A. Ayu Komang Indah Luh Nela Andriani Luh Putu Ratna Sundari Made Ary Pradnyawati Made Karma Maha Wirajaya Manuaba, I.A. Ratih Wulansari Mulana, Victorinus Alfred Saptiono Mulana, Viktorinus Alfred Saptiono Ni Luh Ariwati Ni Luh Gde Ari Natalia Yudha Ni Luh Putu Eka Diarthini Ni Luh Rustini Ni Luh Rustini Ni Made Linawati Ni Made Sudiari Ni Putu Aryati Suryaningsih Ni Putu Widya Astuti Ni Wayan Mita Arisia Nurwiyanti, . Nyoman Titin Brimantari Nyoman Trisna Aryanata Oktayanti, Leny Prapti Wujani, Ni Luh Gede Puspa, Intan Putu Ayu Asri Damayanti Putu Ayu Asri Damayanti Putu Ayu Indrayathi Putu Ika Farmani Putu Indah Budi Apsari R. Niruri Rasmaya Niruri Rasmaya Niruri Rasmaya Niruri Rini Noviyani Sagun Chandra Yowani Sanjaya, I Putu Maheswara Dharma Septiari, I Gusti Ayu Agung Sri Laksemi, Dewa Ayu Agus Suadnyana, Ida Ayu Astiti Teri, Komang Triastawan, I Komang Agus Viktorinus Alfred Saptiono Mulana Vitalia Fina Carla Rettobjaan Widowati, I Gusti Ayu Rai - Widyani, Ni Made Wimpie I Pangkahila Wintariani, Ni Putu Wirajaya, Karma Maha Yudha, A.A. Ngurah Bagus Arista Yuniantari, Ni Wayan