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All Journal Indonesian Journal of Pharmaceutical Science and Technology Biota Majalah Obat Tradisional Pharmascience JFL : Jurnal Farmasi Lampung JPSCR : Journal of Pharmaceutical Science and Clinical Research Journal of Multidisciplinary Applied Natural Science Jurnal Abdimas Kartika Wijayakusuma Jurnal Inovasi Pembangunan Jurnal Media Pengabdian Kepada Masyarakat (JM-PKM) Jurnal Pengabdian Masyarakat Bangsa
Susanti, Laila
Universitas Tulang Bawang
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Activity Test of Durian Peels Essential Oil (Durio zibethinus) as an Antipediculosis Against Pediculus humanus capitis Linn. (Anoplura: Pediculidae) Yuli Wahyu Tri Mulyani; Siti Nurjanah; Samsuar Samsuar; Laila Susanti
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 6, No 3 (2021)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v6i3.49900

Abstract

Pediculosis is a disease caused by infestation of head lice (Pediculus humanus capitis) which is a blood-sucking obligate ectoparasite. The essential oil of durian fruit peel has active compounds that have the potential as vegetable pediculosides that can kill head lice. This study aimed to find the best concentration of essential oil from durian fruit peels that can kill head lice. The research design used with an essential oil concentration of 100%, 75%, 50%, 25%, distilled water as negative control and permethrin 1% as positive control, three repetitions and each concentration consisting of 10 flea tails. The parameters observed were the condition of lice morphologically based on the activity of limb movement, antenna movement and digestion, then the calculation of mortality was observed based on the time of the test. The results showed that the concentration of durian peel essential oil as an antipediculosis had a significant effect on the time of death of head lice, limb movement and digestion. The test result showed that the concentration is 100%, has a death time of 12 minutes 32 seconds, 75% concentration was 16 minutes 28 seconds, 50% concentration was 21 minutes 11 seconds, 25% concentration was 32 minutes 23 seconds, negative control was 61 minutes 15 seconds. The fastest time of death in positive control for chemical pediculosides was 10 minutes 15 seconds. The conclusion in this study was that essential oils the dominan one is 1,5-naphthyridin-2-amine were proven to kill head lice and the best concentration was close to positive control, namely at a concentration of 100%.
Bioautography and FTIR Analysis of Ethanol Fraction Morel Berry Root (Physalis angulata L.) Against Staphylococcus epidermidis and Pseudomonas aeruginosa Pratika Viogenta; Latifah Megasari; Laila Susanti
Majalah Obat Tradisional Vol 27, No 3 (2022)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.78171

Abstract

Morel berry root contains flavonoids, tannins, and alkaloids that have an antibacterial characteristics. This study aims to determine the antibacterial activity of the morel berry root ethanol fraction against Staphylococcus epidermidis and Pseudomonas aeruginosa and the most effective active compounds to inhibit such activity. Extractions of morel berry root used the maceration method with ethanol 70% of and then continued by fractionation using ethanol, chloroform, and n-hexane. Test of the compound fraction was performed using Thin Layer Chromatography (TLC) and characterization with FTIR Spectrophotometer. The results of the antibacterial activity with inhibitory zone diameter were at a 100% concentration of 18.69 mm in S. epidermidis while P. aeruginosa of 20.00 mm. Bioautographic results for ethanol fraction indicate an inhibited zone with an Rf value of 0.72 in the S. epidermidis and P. aeruginosa which is thought to be a flavonoid compound. Characterization with FTIR spectrophotometer functional groups O-H phenol, C = C aromatic, C-H aromatic, C-O alcohol, and C-H aliphatic in ethanol fraction with Rf 0.72.
Antibacterial Activity and Bioautography of the Chloroform Fraction of Morel Berry (Physalis angulata L.) Root Against Staphylococcus epidermidis and Pseudomonas aeruginosa Pratika Viogenta; Laila Susanti; Latifah Megasari
Journal of Multidisciplinary Applied Natural Science Vol. 3 No. 1 (2023): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.148

Abstract

The urgency of finding novel sources of active compounds to overcome infectious diseases is encouraged. Morel berry (Physalis angulata L.) is a traditional herbal plant that can be used as an antimicrobial because of its unique chemical content. This study aims to find compounds that have antibacterial activity from the chloroform fraction of morel berry roots. This study used the Kirby-Bauer method with concentrations of 20%, 40%, 60%, 80%, and 100% against Staphylococcus epidermidis and Pseudomonas aeruginosa bacteria. Determination of antibacterial compounds and their functional groups was performed using thin-layer chromatography (TLC) technique and reagent spray test, TLC-Bioautography and Fourier transforms infrared (FTIR) studies. The chloroform fraction of morel berry showed a zone of inhibition with the highest diameter of 11.50 and 12.00 mm against S. epidermidis and P. aeruginosa, respectively. Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, and saponins in the chloroform fraction. The relative retention stain of 0.54 on the TLC plate inhibited the growth of the two tested bacteria and indicated the presence of functional groups O-H phenol, C-H aliphatic, C=O ester, C=C aromatic, C-OH alcohol, and C-H aromatic. This study found that tannins in the roots of morel berries could be used as a natural antibacterial agent to treat S. epidermidis and P. aeruginosa.
Formulasi Dan Uji Aktivitas Sediaan Krim Fraksi Etanol Bunga Pepaya (Carica Papaya L.) Terhadap Bakteri Staphylococcus Aureus Penyebab Jerawat Widodo, Subur; Rokiban, Akhmad; Susanti, Laila; Riyanti, Deski
JFL : Jurnal Farmasi Lampung Vol. 12 No. 2 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i2.1248

Abstract

Papaya flowers in the community are believed to be antidiabetics, prevent cancer, lower cholesterol, and as antibacterial. Based on its antibacterial properties, the ethanol fraction of papaya flowers will be made in the form of cream preparations. This study aims to find out the activity of papaya flower ethanol fraction cream preparations against the bland growth power of acne-causing Staphylococcus aureus bacteria. Ethanol fractions of papaya flower are formulated into cream preparations with fraction concentrations of F1 (2%), F2 (4%), F3 (6%), and F4 (8%) using oil phases (stearic acid, paraffin liquidum, and adeps lanae), water phase (TEA and aquadest) and preservatives (methyl parabens). Furthermore, the cream tested antibacterial activity and physical properties include homogeneity, organoleptic, pH, viscosity, scattering power, adocity and stability. The results showed F1, F2, F3, and F4 each had antibacterial activity against Staphylococcus aureus bacteria as evidenced by the presence of bland zones in F1 (17.35 mm), F2 (17.77 mm), F3 (18.90 mm), and F4 (19.73 mm). The resulting data is normal and homogeneous distributed data so that the results of the ANOVA test show a significant difference of 0.0000 (p ≤ 0.05) and Tukey Post Hoc test results are obtained significant differences between formulas. The results of the evaluation of cream preparations on observation of homogeneity are less stable and organoleptic have stable results, pH values of 5.62-6.62, viscosity of 4122-4432 cps, scatter power of 5.13-5.70 cm, and akat for 4.86-6.43 seconds. Cycling tests showed stable results in F1, F2 and F3 and less stable in F4. The conclusion of this research is that the formulation ethanol fraction of papaya flower cream preparations has activity against the inhibition of the growth of acne-causing Staphylococcus aureus bacteria. Keywords: Acne, Antibacterial, Carica papaya, Cream, Fraction, Papaya Flower
Formulasi Sediaan Pewarna Pipi Dari Ekstrak Daun Jawer Kotok (Plectranthus scutellarioides (L.) R.Br) Dalam Bentuk Compact Powder Susanti, Laila; Widodo, Subur; Nurjanah, Siti; Sivitha, Sivitha
JFL : Jurnal Farmasi Lampung Vol. 12 No. 2 (2023): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v12i2.1305

Abstract

Blush on was cosmetic used to color the cheeks so that it can improve fresh impression in makeup. Plectranthus scutellarioides (L.) R.Br has anthocyanin content could be used as a natural dye. This research aims to make a rouge from Plectranthus scutellarioides (L.) R.Br extract in the form of compact powder. To get Plectranthus scutellarioides (L.) R.Br extraction we had to macerate 3 kilogram Plectranthus scutellarioides (L.) R.Br into 96% etanol liquid then the maserate is evaporated with rotary evaporator to obtained thick extract. Further more rouge were formulated with kaolin, talc, zinc stearate, oleum rosae, isopropyl myristate, lanolin, and nipagin. Plectranthus scutellarioides (L.) R.Br extract with variations in concentration 6% (F1), 8% (F2) and 10% (F3). After that could be evaluated (color dispersion test, crack test, polishing test, irritation test, hedonic test, and stability test. The results from Plectranthus scutellarioides (L.) R.Br extract result color light brown for F1, red brown for F2 and dark red for F3. Based on the test result all formulation had a homogeny color, not cracked in the crack test qualify for the irritation test. Dosage formulations with concentration 10% many liked. While on the method low temperature stability all preparations no changed organoleptic (color, smell and shape) but in the test high temperature stability of all formulations the preparation has a slight discoloration at thefourth week. The color looks faded not like the beginning. It is because the content of anthocyanin contained in Plectranthus scutellarioides (L.) R.Br extract decreases. Plectranthus scutellarioides (L.) R.Br extract cannot be formulated as a rouge because does not give color in the polish test, powder is rough so the color cannot stick to the skin. Keywords : Plectranthus scutellarioides (L.) R.Br, Coleus atropurpureus (L.) Benth, rounge, formulation
suburwidodo Formulasi Krim Anti Acne Ekstrak Etanol Kulit Kentang (Solanum Tuberosum L.) Dan Aktivitas Antibakteri Terhadap Staphylococcus epidermidis Dan Propionibacterium acnes.: Anti Acne Cream Formulation Of Potato Ethanol Extracts (Solanum Tuberosum L.) And Antibacterial Activities On Staphylococcus epidermidis And Propionibacterium acnes. Widodo, Subur; Susanti, Laila; Samsuar; Hartono, Adityo; Safitri, Andika
JFL : Jurnal Farmasi Lampung Vol. 13 No. 1 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i1.1646

Abstract

Pengobatan jerawat di klinik kulit biasanya menggunakan antibiotik yang dapat menghambat inflamasi dan membunuh bakteri. Penggunaan antibiotik jangka panjang dapat menimbulkan resistensi antibiotik. Efek samping penggunaan antibiotik dapat dikurangi dengan mengganti bahan aktif obat yang diperoleh dari alam seperti kulit kentang yang mampu menghambat pertumbuhan bakteri penyebab jerawat. Penelitian ini bertujuan untuk membuktikan bahwa ekstrak kulit kentang dapat di formulasikan menjadi sediaan krim dan memiliki aktivitas antibakteri terhadap S.epidermidis dan P.acnes. Ekstrak diformulasikan dalam sediaan krim dengan konsentrasi ekstrak berbeda yaitu F1 (15%), F2 (30%) dan F3 (45%) dengan menggunakan asam stearat, paraffin liquidum, adeps lanae sebagai fase minyak dan TEA, aquadest sebagai fase air, dan metil paraben sebagai pengawet. Kemudian diuji sifat fisik sediaan meliputi ,homogenitas, pemeriksaan organoleptis, pengukuran pH, viskositas, daya sebar, daya lekat, uji stabilitas dan uji antibakteri. Hasil evaluasi sediaan memiliki nilai pH berkisar  antara 6,2 - 8,1, viskositas berkisar antara  3120  - 4920 cps, daya sebar antara 5,3 - 6,7 cm, dan daya lekat 4,2 - 5,3 detik. Setiap formula stabil dalam penyimpanan cycling test serta penyimpanan suhu 40ºC ± 2ºC, 28ºC ± 2ºC, 4ºC ± 2ºC dan ketiga formula memiliki sifat antibakteri terhadap S.epidermidis dan P.acnes. Luas zona hambat F1 (7,61 mm), F2 (8,47 mm) dan F3 (9,92 mm) terhadap S.epidermidis dan Luas zona hambat F1 (7,58 mm), F2 (7,86 mm) dan F3 (9,65 mm) terhadap P.acnes. Kesimpulan penelitian ini yaitu ekstrak kulit kentang dapat diformulasikan dalam sediaan krim dan memiliki zona hambat terhadap S.epidermidis dan P.acnes.
AKTIVITAS ANTIHIPERURISEMIA KOMBINASI EKSTRAK DAUN KERSEN (MUNTINGIA CALABURA L.) DAN DAUN SIRSAK (ANNONA MURICATA L.) TERHADAP TIKUS PUTIH JANTAN: ANTIHYPERURICEMIA ACTIVITY OF EXTRACT COMBINATION OF KERSEN LEAF (MUNTINGIA CALABURA L.) AND SOURSOP LEAF (ANNONA MURICATA L.) ON MALE WHITE RATS Susanti, Laila; Samsuar; Ariawan, M Wahyu; Widiyastuti, Asih; Isbiyantoro; Widodo, Subur
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1908

Abstract

Kersen (Muntingia calabura L.) and soursop (Annona muricata L.) have many properties to cure several diseases, including antihiperurisemia, which is a disorder of purine metabolism in which patients experience increased uric acid levels. This study aimed to examine the antihiperuricemia effect of a combination of kersen leaf extract and soursop in male rats orally. Extraction was carried out by maceration using 70% ethanol. This research is a laboratory experimental study using male white mice as test animals. Data were processed in the form of ANOVA and LSD (Least Significant Difference) test results to compare between groups P0 (normal control), PI (negative control), P2 (Allopurinol 9 mg/Kg BW), P3 (410 and 3.5 mg/Kg BW), P4 (410 and 7 mg/Kg BW), P5 (410 and 10.5 mg/Kg BW), P6 (610 and 3.5 mg/Kg BW), P7 (610 and 7 mg/Kg BW), P8 (610 and 10.5 mg/Kg BW), P9 (910 and 3.5 mg/Kg BW), P10 (910 and 7 mg/Kg BW) ), P11 (910 and 10.5 mg/Kg BW). Giving the test material starting on the 8th to 14th day. On the 15th day blood was taken by slaughtering to measure uric acid levels using a UV-Vis spectrophotometer. On examination of uric acid levels, the administration of beef liver can significantly increase uric acid levels in male rats. and the administration of kersen leaf extract and soursop leaves can significantly reduce uric acid levels in male rats. The administration of kersen leaf extract and soursop leaves for 7 days at doses of 910 and 10.5 mg/Kg BW most effectively reduced uric acid levels in hyperuricemic mice.   Keywords: Hyperuricemia, kersen leaves extract, soursop leaves extract  
Peningkatan Keterampilan Public speaking dan Entrepreneurship untuk Membentuk Generasi Santri Unggul di Pondok Pesantren Putra Darul Fattah Lampung Selatan Susanti, Laila; Evadianti, Yuli; Suhartina, Suhartina
Jurnal Abdimas Kartika Wijayakusuma Vol 6 No 1 (2025): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jakw.v6i1.647

Abstract

Pondok Pesantren Putra Darul Fattah (SMPQ DF Putra Boarding) yang terletak di Desa Tanjung Sari, Lampung Selatan, menghadapi tantangan dalam pengembangan keterampilan public speaking siswa/santri, serta kebosanan terhadap kegiatan ekstrakurikuler yang ada. Untuk mengatasi masalah ini, program pengabdian ini bertujuan meningkatkan keterampilan public speaking melalui pembelajaran menjadi content creator dengan platform podcast dan mengembangkan jiwa entrepreneurship melalui pelatihan urban farming berbasis hidroponik. Metode yang digunakan meliputi pelatihan dan pendampingan untuk memberikan pengalaman langsung kepada siswa. Hasil dari program ini menunjukkan peningkatan keterampilan berbicara di depan umum dengan pendekatan yang lebih inovatif, serta bertambahnya jumlah subscriber dan viewer pada channel YouTube sekolah. Selain itu, siswa/santri juga menunjukkan peningkatan dalam jiwa entrepreneurship dan pemahaman tentang urban farming berbasis hidroponik, termasuk tahapan mulai dari pembuatan media semai, penyemaian, perawatan, hingga pengemasan produk untuk dijual. Program ini diharapkan dapat membentuk generasi santri yang unggul dan siap menghadapi tantangan di era digital.
FORMULATION AND ANTIBACTERIAL ACTIVITY OF MOUTHWASH COMBINATION OF GUAVA LEAF (Psidium guajava L.) AND BASIL LEAF (Ocinum basilicum L.) EXTRACT AGAINST Streptococcus mutans : FORMULASI SEDIAAN MOUTHWASH KOMBINASI EKSTRAK DAUN JAMBU BIJI (Psidium guajava L.) DAN DAUN KEMANGI (Ocinum basilicum L.) TERHADAP AKTIVITAS BAKTERI Streptococcus mutans Samsuar, Samsuar; Ariawan, M Wahyu; Pratiwi, Inda; Widodo, Subur; Susanti, Laila; Luthfiyah, Yosi
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2427

Abstract

Dental caries is basically caused by cariogenic bacteria, including Streptococcus mutans, which are found in the oral cavity, especially dental plaque. To treat dental caries, antiseptics packaged in the form of mouthwash use unnatural active ingredients which often cause side effects. Therefore, it is necessary to carry out preventive measures to reduce side effects by using waste from guava leaves and basil leaves. This research purpose were to making mouthwash formulation with the active ingredients guava leaf extract and basil leaf extract and determine the antibacterial activity of mouthwash formulation. The method used is the diffusion method, a combination of concentrations of guava leaf extract and basil leaves, namely F1(0%+20%), F2(5%+15%), F3(10%+10%), F4( 15%+ 5.0%), F5(20%+0%), F6(15%+15%). In this study, the variable measured in this study was the diameter of the inhibition zone formed by the combination of extracts. Data analysis was tested using One Way Anova. The significant value obtained was 0.00 ≤ 0.05, indicating a significant difference from the formulation containing a combination of extracts. The results of this research showed that the largest inhibitory zone was at F5 with the largest average value of 15.07mm which had a strong inhibitory response. This research can be concluded that the mouthwash formulation of extracts meets the physical requirements and can inhibit S. mutans. Keywords :  Guava, basil, mouthwash, S. mutans
Membentuk Pribadi Hebat: Penguatan Nilai Karakter Anak Melalui Social Project Humanis Alfi, Cindya; Kholida, Nilna Maya; Fauzi, Fariha Qalbi Ilmillahi; Putri, Alvina Adelia; Abdiyati, Santi Asfiyatul; Munadhah, Ummu Khusna; Agustina, Aulia; Aprilia, Linda Ayu Resa; Mulia, Niken Ayu Dewanti; Mulia, Wanda Natasya Dewanti; Susanti, Laila; Rahmania, Nayla; Sa'adah, Isnawaitus; Ananta, Nadia Diaz; Affiana, Maulidya Nur
Jurnal Pengabdian Masyarakat Bangsa Vol. 3 No. 5 (2025): Juli
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v3i5.2667

Abstract

Kegiatan Social Project bertema “Menjadi Pribadi Hebat dengan Karakter Kuat” merupakan bentuk pengabdian mahasiswa kepada masyarakat yang dilaksanakan di Panti Asuhan Yargis, Kota Blitar. Tujuannya yaitu membentuk pribadi hebat pada anak-anak panti melalui penguatan nilai-nilai karakter seperti gotong royong, kemandirian, kreativitas, dan kemampuan berpikir kritis. Pendekatan yang digunakan bersifat humanis dan partisipatif, berbasis pengalaman nyata yang menyenangkan dan kontekstual. Kegiatan inti mencakup seminar edukatif, lomba cerdas cermat, estafet mewarnai, dan menari bersama. Hasil kegiatan menunjukkan peningkatan positif dalam sikap, partisipasi, dan antusiasme anak-anak panti, serta terbentuknya interaksi yang hangat antara peserta dan panitia. Selain berdampak pada perkembangan karakter anak, kegiatan ini juga menjadi sarana reflektif bagi mahasiswa sebagai calon pendidik dan agen perubahan sosial. Respons positif dari pihak panti dan peserta memperkuat keberhasilan social project humanis ini dalam mendukung pembinaan karakter secara menyenangkan, bermakna, dan berkelanjutan.
Co-Authors Abdiyati, Santi Asfiyatul Affiana, Maulidya Nur Ananta, Nadia Diaz Anita Setiawati Aprilia, Linda Ayu Resa Aulia Agustina, Aulia Cindya Alfi Dyah Rahmawati Fauzi, Fariha Qalbi Ilmillahi Hartono, Adityo Isbiyantoro Isbiyantoro Isbiyantoro Kholida, Nilna Maya Latifah Megasari Latifah Megasari Lilik Koernia Wahidah Luthfiyah, Yosi M. Wahyu Ariawan Mashuri Yusuf Meidaliyantisyah Meidaliyantisyah Merinda Setyowati Mulia, Niken Ayu Dewanti Mulia, Wanda Natasya Dewanti Munadhah, Ummu Khusna Pratiwi, Inda Putri, Alvina Adelia qurrota aini Rahmania, Nayla Rahmawati, Dyah Retno Fardila Sari Riyanti, Deski Rokiban, Akhmad Sa'adah, Isnawaitus Safitri, Andika Samsuar Samsuar Samsuar Samsuar User Samsuar, Samsuar Septiana Simanjuntak Siti Nurjanah Siti Nurjanah Sivitha, Sivitha Suhartina Suhartina, Suhartina Syaiful Bahri Viogenta, Pratika Wenny Indriasari Widiyastuti, Asih Widodo, Subur Yuli Evadianti, Yuli Yuli Wahyu Tri Mulyani Yuli Wahyu Tri Mulyani