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All Journal Jurnal Biosains Pascasarjana Jurnal Analis Kesehatan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Kesehatan Poltekita : Jurnal Ilmu Kesehatan Jaringan Laboratorium Medis Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan Academic Hospital Journal E-Amal: Jurnal Pengabdian Kepada Masyarakat
Kuncara, Rachmad Bayu
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Jurnal Biosains Pascasarjana

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DIFFERENCES IN INTERFERON GAMMA LEVELS IN TREATMENT OF TUBERCULOSIS IN INTENSIVE PHASE AND ADVANCED PHASE Kuncara, Rachmad Bayu; SY. Didik Widiyanto; Ririh Jatmi Wikandari; Wiwit Sulistyasmi
Jurnal Biosains Pascasarjana Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i1.2024.72-76

Abstract

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis complex (MTBC). Anti-tuberculosis drugs given to active TB sufferers consist of 3 or 4 combinations. Tuberculosis treatment is divided into intensive phase treatment (2 weeks) and continuation phase (16 weeks / 4 months). Interferon gamma (IFN γ) is a protein belonging to the cytokine family which plays a role in eliminating MTB bacteria through a cell-mediated immunity mechanism. The aim of this study was to analyze differences in gamma interferon levels in the intensive phase and advanced phase of tuberculosis treatment. This research method is an analytical observational study with a cross-sectional design (cross sectional study). The research design used was a randomized post test only control group design. Data were analyzed using the Kruskal Wallis test with statistical test results obtained with a p value of 0.033 (> 0.05), meaning there was a difference in IFN γ levels in the intensive phase and advanced phase of tuberculosis treatment.
Co-Authors Anung Sugihantono Auliya, Qurrotu A’yuni Azahra, Sresta Dina Afrianti1 Djoko Priyatno, Djoko Duri, Iin Desmiany Fuzianingsih, Eka Noviya Hadipranoto, Ichsan Istiqomah, Anisa Kasiyati, Menik Najiah, Dewina Zumrotin Nastiti, Hilari Rio Rosa Nurul Qomariah Nurul Qomariyah Purlinda, Devi Etivia Putri, Adita Puspitasari Swastya Ririh Jatmi Wikandari Rodhi Hartono Roni Afriansya Sasangka, Parisade Galih Setyaji, Yoki Setyowatiningsih, Lilik SY. Didik Widiyanto Teguh Budiharjo, Teguh Widiyanto, SY. Didik Widodo Widodo Wiwit Sulistyasmi Zatalini, Karinta Syifa