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All Journal Jurnal Delima Harapan JURNAL FARMASIMED (JFM) Jurnal Review Pendidikan dan Pengajaran (JRPP) Jurnal Analis Farmasi PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Peduli Masyarakat Jurnal Kesehatan Tambusai Jurnal Buana Farma JAF (Jurnal Analis Farmasi) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Duta Pharma Journal Proceeding of International Conference Health, Science And Technology (ICOHETECH) Prosiding Seminar Informasi Kesehatan Nasional International Journal of Health, Engineering and Technology Inovasi Jurnal Pengabdian Masyarakat (IJPM) Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Pengabdian Masyarakat dan Riset Pendidikan EduInovasi: Journal of Basic Educational Studies Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Anna Fitriawati
Universitas Duta Bangsa Surakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Proceeding of International Conference Health, Science And Technology (ICOHETECH)

 1 
ACTIVITY OF INHIBITING THE GROWTH OF STAPHYLOCOCCUS AUREUS ATCC 25923 LEAVES OF DURI SPINACH (AMARANTHUS SPINOSUS LINN. ) USING THE MACERATION METHOD Fitriawati, Anna; Lestari, Vera Fuji; Dwi S, Anita
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2023: Proceeding of the 4th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v4i1.3386

Abstract

Antibacterial is a substance that can inhibit or kill the growth of bacteria. One of the plants that can be used for antibacterial is spinach thorns. Spinach (Amaranthus spinosus Linn.) is a plant originating from the tropical lowlands of America, widely distributed in the tropics and subtropics of Africa, Southeast Asia and in India and even in Indonesia. The purpose of this study was to determine the activity of spinach leaves (Amaranthus spinosus Linn.) on inhibiting the growth of Staphylococcus aureus bacteria by maceration method. This study uses an experimental method. Spinach leaves (Amaranthus spinosus Linn.) were macerated using 70% ethanol solvent. The concentrations used for each method were concentrations of 30%, 40%, 50%, ciprofloxacin positive control and 1% DMSO negative control. Each of these concentrations was tested for antibacterial activity against Staphylococcus aureus using the diffusion and dilution method. The results of the antibacterial activity test by diffusion in the maceration method obtained an average inhibition zone result at a concentration of 30% of 8.73mm, a concentration of 40% of 9.93mm, a concentration of 50% of 11.53mm and a positive control of 12.73mm.
Antioksidan Ekstrak Etanol Daun Pedada (Sonneratia ovata Backer) Raharjo, Danang; Fitriawati, Anna; Aminulloh, Muhammad
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4194

Abstract

Free radicals are reactive oxygen compounds that are known to be compounds that have free or unpaired electrons. Free radicals will look for new partners so that they will easily bind to other substances such as proteins, fats, and DNA in the body, resulting in cell damage and causing various degenerative diseases. To overcome the negative effects of free radicals, a substance that acts as an antioxidant is needed. Sonneratia Ovata or often called pedada by coastal communities is often used to treat various diseases including diabetes, ulcers, analgesic diarrhea, inflammation, pain and accelerate wound healing. This study aims to examine the levels of flavonoid compounds in the ethanol extract of S. ovata leaves using the colorimetric method and antioxidant activity using the ABTS method (2,2 azinobis (3-ethylbenzothiazolin-6- sulfonic acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl) on the ethanol extract of S. ovata leaves. The research process began with the extraction of S. ovata leaves with 96% ethanol, followed by determination of total flavonoid levels and antioxidant testing. From the results of the determination of total flavonoid levels, it was found that the ethanol extract of S. ovata leaves had a flavonoid content of 38,248 ± 0.142 mgQE/gram. In measuring antioxidant activity using the DPPH and ABTS methods, the IC50 values were 31.785 ± 0.047 ppm and 28.303 ± 0.558 ppm, respectively. Based on these results, the ethanol extract of S. ovata provided very strong antioxidant activity with an IC50 value of less than 50 ppm.
Growth Inhibiting Activity Of Staphylococcus Aureus ATCC 25923 Kirinyuh Leaves (Chromolaena Odorata L.) Using The Soxhletation Method Fitriawati, Anna; Rahmad Adji, Alenda; Ardiyantoro, Bagas; Abdul Wahab Sabrina, Azimah; Karim, Karim
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4227

Abstract

Kirinyuh leaves (Chromolaena odorata L.) have the potential as a medicinal plant because of the active compounds contained in kirinyuh leaves (Chromolaena odorata L.). The purpose of this study was to determine the antibacterial activity of ethanol extract of kirinyuh leaves (Chromolaena odorata L.) against the growth of Staphylococcus aureus ATCC 25923 bacteria. Kirinyuh leaf extract (Chromolaena odorata L.) was carried out using the soxhletation method and the solvent used was 96% ethanol. The concentrations used for each treatment were 30%, 40% and 50%. Each concentration was tested for antibacterial activity against Staphylococcus aureus bacteria using the disc diffusion method. The results showed that the extract of kirinyuh leaves (Chromolaena odorata L.) with a concentration of 30% had an average diameter of the inhibition zone of 9.2 mm, a concentration of 40% had an average diameter of the inhibition zone of 12.36 mm, and a concentration of 50% had an average diameter of the inhibition zone of 13.71 mm. The research conducted can be concluded that the extract of kirinyuh leaves can provide the best effect of inhibiting bacterial growth at a concentration of 50% with the results of the anova test p <0.05 which means there is a significant difference compared to other concentrations
OPTIMIZATION OF CLAY MASK FORMULA FROM LEAF SI KEJUT (Mimosa pudica L.) EXRACT USING SIMPLEX LATTICE DESIGN METHOD Fitriawati, Anna; Rahmatillah, Annie; Agustiningrum, Nurul
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2025: Proceeding of the 6th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/bss4fn77

Abstract

Clay mask is a facial mask used to remove dirt and blackheads from the skin. It is particularly suitable for acne-prone skin, as clay masks provide a refreshing sensation, absorb excess oil, and help manage blackheads. Mimosa pudica, commonly known as the "Sensitive Plant" or "Touch-me-not," contains bioactive compounds such as alkaloids, flavonoids, tannins, and saponins. According to a study by Utami et al. (2021), Mimosa pudica L. leaves exhibit strong inhibitory effects against Propionibacterium acnes, the primary bacterium responsible for acne. The objective of this research is to determine the optimal formulation of ethanol extract from Mimosa pudica leaves in a clay mask using the Simplex Lattice Design (SLD) method. Optimization was performed by comparing two clay base formulations—kaolin and bentonite. Physical quality testing included organoleptic evaluation, homogeneity, adhesion strength, spreadability, pH testing, and drying time. The results of the physical quality tests were analyzed using Design Expert software. Through the Simplex Lattice Design (SLD) method, the optimal formula was identified as Formula I, containing 34.75% kaolin and 6.25% bentonite.
ACTIVITY OF INHIBITING THE GROWTH OF STAPHYLOCOCCUS AUREUS ATCC 25923 LEAVES OF DURI SPINACH (AMARANTHUS SPINOSUS LINN. ) USING THE MACERATION METHOD Fitriawati, Anna; Lestari, Vera Fuji; Dwi S, Anita
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2023: Proceeding of the 4th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v4i1.3386

Abstract

Antibacterial is a substance that can inhibit or kill the growth of bacteria. One of the plants that can be used for antibacterial is spinach thorns. Spinach (Amaranthus spinosus Linn.) is a plant originating from the tropical lowlands of America, widely distributed in the tropics and subtropics of Africa, Southeast Asia and in India and even in Indonesia. The purpose of this study was to determine the activity of spinach leaves (Amaranthus spinosus Linn.) on inhibiting the growth of Staphylococcus aureus bacteria by maceration method. This study uses an experimental method. Spinach leaves (Amaranthus spinosus Linn.) were macerated using 70% ethanol solvent. The concentrations used for each method were concentrations of 30%, 40%, 50%, ciprofloxacin positive control and 1% DMSO negative control. Each of these concentrations was tested for antibacterial activity against Staphylococcus aureus using the diffusion and dilution method. The results of the antibacterial activity test by diffusion in the maceration method obtained an average inhibition zone result at a concentration of 30% of 8.73mm, a concentration of 40% of 9.93mm, a concentration of 50% of 11.53mm and a positive control of 12.73mm.
Antioksidan Ekstrak Etanol Daun Pedada (Sonneratia ovata Backer) Raharjo, Danang; Fitriawati, Anna; Aminulloh, Muhammad
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4194

Abstract

Free radicals are reactive oxygen compounds that are known to be compounds that have free or unpaired electrons. Free radicals will look for new partners so that they will easily bind to other substances such as proteins, fats, and DNA in the body, resulting in cell damage and causing various degenerative diseases. To overcome the negative effects of free radicals, a substance that acts as an antioxidant is needed. Sonneratia Ovata or often called pedada by coastal communities is often used to treat various diseases including diabetes, ulcers, analgesic diarrhea, inflammation, pain and accelerate wound healing. This study aims to examine the levels of flavonoid compounds in the ethanol extract of S. ovata leaves using the colorimetric method and antioxidant activity using the ABTS method (2,2 azinobis (3-ethylbenzothiazolin-6- sulfonic acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl) on the ethanol extract of S. ovata leaves. The research process began with the extraction of S. ovata leaves with 96% ethanol, followed by determination of total flavonoid levels and antioxidant testing. From the results of the determination of total flavonoid levels, it was found that the ethanol extract of S. ovata leaves had a flavonoid content of 38,248 ± 0.142 mgQE/gram. In measuring antioxidant activity using the DPPH and ABTS methods, the IC50 values were 31.785 ± 0.047 ppm and 28.303 ± 0.558 ppm, respectively. Based on these results, the ethanol extract of S. ovata provided very strong antioxidant activity with an IC50 value of less than 50 ppm.
Growth Inhibiting Activity Of Staphylococcus Aureus ATCC 25923 Kirinyuh Leaves (Chromolaena Odorata L.) Using The Soxhletation Method Fitriawati, Anna; Rahmad Adji, Alenda; Ardiyantoro, Bagas; Abdul Wahab Sabrina, Azimah; Karim, Karim
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4227

Abstract

Kirinyuh leaves (Chromolaena odorata L.) have the potential as a medicinal plant because of the active compounds contained in kirinyuh leaves (Chromolaena odorata L.). The purpose of this study was to determine the antibacterial activity of ethanol extract of kirinyuh leaves (Chromolaena odorata L.) against the growth of Staphylococcus aureus ATCC 25923 bacteria. Kirinyuh leaf extract (Chromolaena odorata L.) was carried out using the soxhletation method and the solvent used was 96% ethanol. The concentrations used for each treatment were 30%, 40% and 50%. Each concentration was tested for antibacterial activity against Staphylococcus aureus bacteria using the disc diffusion method. The results showed that the extract of kirinyuh leaves (Chromolaena odorata L.) with a concentration of 30% had an average diameter of the inhibition zone of 9.2 mm, a concentration of 40% had an average diameter of the inhibition zone of 12.36 mm, and a concentration of 50% had an average diameter of the inhibition zone of 13.71 mm. The research conducted can be concluded that the extract of kirinyuh leaves can provide the best effect of inhibiting bacterial growth at a concentration of 50% with the results of the anova test p <0.05 which means there is a significant difference compared to other concentrations
Co-Authors Abdul Wahab Sabrina, Azimah Adhe Wibawa Mahardika Putra Agustiningrum, Nurul Alya Atla Lidya Aminnulloh, Muhammad Aminnulloh, Muhhamad Aminulloh, Muhammad Anisa Fadilah Kumala Putri Bagas Ardiyantoro Bangkit Riska P Bryan Dwi Multi Danang Raharjo Dwi S, Anita Emin Karoba Endang Suciati Evania Yudya Prameswari, Ninda Hasna Afifah, Diyana Hendra, Naufal Dhuha Indi yatno, Aurora Shalfa Alkhariza Karim Karim, Karim Kharisma Jayak P Kusumaningrum, Indah Mega Lestari, Vera Fuji Listyani, Tiara Ajeng Luthfiyanti, Niken Muhammad Abdul Azis Nia Kurniati Ningrum, Della Puspita ningsih, endang wahyu Nurul Fatimah Olga Nordeka, Marcela P, Kharisma Jayak Peni Indrayudha Permata, Bangkit Riska Pradina Arifah Nurcahyani Pratama, Kharisma Jayak Prity, Intan Qurrota'Ain, Rusyda Raden Rara Anteng Pujowati Rahmad Adji, Alenda Rahmat Hidayat Rahmatillah, Annie Riska P, Bangkit Riska Permata, Bangkit Riztiandi Ardiansyah Rochayati, Popiy Eko Sari, Cantyka Eka Viemala Sari, Sindy Avita Septian Maulid W Septian Maulid Wicahyo siska, Tatiana Tanoyo, William Toyang, Gresilia Wahyu, Rizka Wardani, Lydia Puspita Wardani, Tatiana Siska Wulandari, Diana