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All Journal Jurnal Biologi Tropis Jurnal Kesehatan Global Jurnal Farmasi Indonesia Jurnal Dunia Farmasi Majalah Farmasetika Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences International Archives of Medical Sciences and Public Health International Archives of Medical Sciences and Public Health FARMASAINKES Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Abadi, Hafizhatul
Institut Kesehatan Helvetia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Formulation and Effectiveness Test of Liquid Soap from Siam Weed (Chromolaena odorata (L.) Leaves Ethanol Extract Against Staphylococcus aureus Diana, Vivi Eulis; Abadi, Hafizhatul; Andry, Muhammad
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7981

Abstract

Chromolaena odorata (L.) is one of the plants known as weeds. Alkaloids, flavonoids, saponins, tannins, and glycosides are active chemicals found in Siam weed leaves. The study aimed to see if an ethanol extract of Siam weed leaves can be made into liquid soap and has antibacterial action against Staphylococcus aureus germs. The liquid soap of Siam weed (Chromolaena odorata L.) leaf ethanol extract at concentrations of 3%, 6%, and 9% was carried out experimentally in the laboratory, along with physical liquid soap evaluation tests such as organoleptic test, homogeneity test, pH test, foam height test, specific gravity test, test irritation, and hedonic test. Staphylococcus aureus bacteria were then tested. The assessment test criteria were met by making liquid soap preparations of ethanol extract of Siam weed leaves  at concentrations of 3%, 6%, and 9%. The color of the solid soap was brown - dark brown, and the texture was liquid with a lemon scent; the homogeneity test showed that all preparations were homogeneous; the pH test of the soap was 9.1 -9.7; the foam height test was 53-66 mm; the specific gravity test was 1-1.01 g/ml; and the irritation test revealed that all preparations had no reaction to redness, itching, and swelling on the skin. The hedonic test on skin revealed that all preparations obtained favorable evaluations from the panelists. The antibacterial activity of liquid soap against Staphylococcus aureus germs was F1 3.65 mm, F2 5.75mm, and F3 6.5mm. Based on the results of the Staphylococcus aureus test, it could be concluded that in the formula F1 (3% concentration), F2 (6% concentration) and F3 (9% concentration) had an inhibition zone.
Co-Authors Adek Chan Diana, Vivi Eulis Eulis, Vivi Faadhilah Yusa Simbolon Ignasia Amaerita Buulolo Jacub Tarigan Jamiati Jamiati Khairani Fitri Lathi Furrahmi Linda Hernike Napitupulu Mayang Sari Muhammad Andry Nidawah Nidawah Parhan Parhan Pricella Aqwilla Br Ginting Rani Monalisa Hutagaol Riva Rainiza Zuddin Riva Rainiza Zuddin Rumanti, Ruth Mayana Ruth Mayana Rumanti Septiana, Lilik Sipahutar, Rizki Anjani Siti Fatimah Hanum Siti Netti Ritonga Surbakti, Chemayanti Tetty Noverita Khairani Tetty Noverita Khairani Tri Sundari Vivi Eulis Diana Winata, Hanafis Sastra Yoksan Duha Yusta Suriani Ndruru Zulmai Rani