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Evaluasi Peresepan Antibiotik Pada Pasien Rawat Jalan di Puskesmas Dabun Gelang Kabupaten Gayo Lues Jamiati Jamiati; Hafizhatul Abadi; Mayang Sari
Jurnal Dunia Farmasi Vol 3, No 3 (2019): Edisi Agustus
Publisher : Program Studi Farmasi, Fakultas Farmasi dan Kesehatan, Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdf.v3i3.4482

Pendahuluan; Peresepanan antibiotik bertujuan mengatasi penyakit infeksi (terapi) dan mencegah infeksi pada pasien yang berisiko tinggi untuk mengalami infeksi bakteri pada tindakan pembedahan (profilaksis bedah) dan beberapa kondisi medis tertentu profilaksis medik). Antibiotik tidak di berikan pada penyakit non-infeksi dan penyaki tinfeksi yang dapat sembuh sendiri (self-limited) seperti infeksi virus. Tujuan; Penelitian ini adalah mengetahui pola peresepan antibiotik pada pasien rawat jalan di puskesmas Dabun Gelang Kabupaten Gayo Lues. Metode; Penelitian deskriptif kualitatif dengan pengambilan data secara retrospektif. populasi adalah pasien yang datanya tertulis dalam data resep dengan jumlah populasi 1.244 pasien. Pasien yang menggunakan antibiotik berjumlah 86 pasien. Hasil; Penelitian menunjukan antibiotik yang sering diresepkan adalah antibiotik generik golongan beta lactam yaitu amoksisilin ( 32,6% ). Bentuk sediaan yang banyak digunakan adalah tablet ( 54,7 % ) . Gambaran kesesuaian pemberian antibiotik di Puskesmas Dabun Gelang Kabupaten Gayo Lues dengan pedoman pengobatan dasar puskesmas adalah tepat indikasi 54,6 %, tepat dosis 60,5 % , tepat frekwensi 87,7 % dan tepat durasi 26,7 %. Kesimpulan; Dari penelitian ini Sesuai peresepan antibiotik belum sepenuhnya sesuai dengan pedoman pengobatan dasar di puskesmas dan diharapkan kepada dokter untuk memperhatikan pesesepan antibiotik sehingga di dapatkan terapi antibiotik yang rasional.

Formulasi dan Uji Efektivitas Sabun Padat dari Ekstrak Etanol Daun Kopasanda (Chromolaena odorata L.) terhadap Bakteri Staphylococcus epidermidis Hafizhatul Abadi; Hanafis Sastra Winata; Adek Chan; Faadhilah Yusa Simbolon
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.444

Siam Weed leaf plants contain high levels of flavonoids and tannins. These compounds provide antibacterial potential. This study aims to formulate solid soap dosage form of ethanol extract of Siam weed leaves and test the antibacterial activity of it against the growth of Staphylococcus epidermidis bacteria. This is experimental research. Making the extract phytochemical screening test. Evaluation of the dosage form was done by organoleptic tests, homogeneity, pH, foam height, moisture content, irritation, stability, and antibacterial activity tests using the well method. The results showed that solid bath soap dosage form from the ethanol extract of siam weed leaves could be formulated into soap dosage form which had a pH in the range of 9.2 – 9.8, high foam that was stable and did not cause irritation to the skin of volunteers and tested for antibacterial activity on bacteria. Staphylococcus epidermidis with a concentration of 10% 8.84 mm, 15% concentration 10.56 mm and 20% concentration 12.11 mm. The conclusion showed that solid soap dosage form of ethanol extract of Siam weed leaves (Chromolaena odorata L.) could be formulated and fulfilled the requirements after being evaluated and the antibacterial effectiveness of Staphylococcus epidermidis was the best at a concentration of 20% (strong).

EFEKTIVITAS ANTI JERAWAT SEDIAAN KRIM EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) TERHADAP Propionibacterium acnes Hafizhatul Abadi; Vivi Eulis Diana; Jacub Tarigan; Tetty Noverita Khairani; Tri Sundari
Jurnal Ilmiah Manuntung Vol 7 No 1 (2021): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.419

Jackfruit (Artocarpus heterophyllus Lam.) leaves have medicine potential, such as an antibacterial in anti-acne treatment contain flavonoids, tannins and saponins. The study aims to determine whether the ethanol extract of jackfruit leaves 96% can be formulated and determined the effectiveness of concentration preparation in inhibiting the Propionibacterium acnes bacteria. The preparation of cream preparations used a concentration of 20%, 30% and 40% jackfruit leaf ethanol extract. Then carried out the evaluation test of the preparation including the organoleptic test, homogeneity test, spreadability test, and pH test. Furthermore, the antibacterial effectiveness test was carried out by using the diffusion method. The results of evaluation test for cream preparations which included organoleptic tests with the results of three concentrations meeting the requirements, the homogeneity test and the dispersion test of the preparations, the results meet the specified conditions and the results of the pH test with the three concentrations of preparations that met the specified pH requirements. And it can inhibit the growth of Propionibacterium acnes bacteria with an inhibition zone of 7.5 mm at a concentration of 20%, 11 mm at a concentration of 30%, and 11.7 mm at a concentration of 40%. Antibacterial effectiveness test using positive control had an inhibition zone of 25.9 mm. The conclusion of this study is that the ethanol extract of jackfruit leaves can be formulated into anti-acne cream preparations.

TINGKAT PENGETAHUAN DAN SIKAP MASYARAKAT TENTANG ANTIBIOTIK DI KELURAHAN MANDAILING KECAMATAN TEBING TINGGI KOTA Septiana, Lilik; Hafizhatul Abadi; Sipahutar, Rizki Anjani; Zulmai Rani
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 4 No. 2 (2025): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v4i2.4006

Antibiotics are a group of compounds, both natural and synthetic, that have the effect of suppressing or stopping a biochemical process in an organism, especially in the process of infection by bacteria. This study only describes the object of the study by collecting questionnaire data from the community to determine the knowledge and attitudes of the community about antibiotics in Mandailing Village, Tebing Tinggi District, City. The results of the study obtained from univariate analysis found that the level of knowledge of respondents in the high category was 34 people (35.79%), in the moderate category was 47 people (49.47%), and in the low category was 14 people (14.74%). The total score was 680. At the level of attitude, respondents in the good category were 21 people (22.10%), in the sufficient category were 22 people (23.16%), and in the less category were 52 people (54.74%); the total score was 529. At the level of community knowledge, it was in the moderate category (71.57%), community attitudes were in the less category (55.68%), and there was a relationship between age, education, and occupation with the level of knowledge; there was a relationship between education and occupation with community attitudes about antibiotics; there was a relationship between the level of knowledge and community attitudes about antibiotics in the use of antibiotics in Mandailing Village, Tebing Tinggi District, City.

Formulation And Activity Tests Of Anti Dandruff Shampoo Ethanol Extract Of Peperomia Pellucida (L.) Kunth Leaves On The Growth Of Pityrosporum Ovale Fungus Abadi, Hafizhatul; Eulis, Vivi
International Archives of Medical Sciences and Public Health Vol. 4 No. 1 (2023)
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v4i1.593

Shampoo is a cosmetic preparation used to clean hair. The leaves of Peperomia pellucida (L.) Kunth are one of the plants that can be used to get rid of dandruff. The plants contain alkaloids, saponins, tannins, hydroxylated sesquiterpenes, especially carotol and peppermint which have antifungal activity. Purpose; formulating anti-dandruff shampoo preparations containing suruh leaves, as well as evaluating shampoo preparations which include homogeneity, pH, organoleptic tests, foam height, viscosity, and irritation. Method; The research method used was an experimental method, namely Peperomia pellucida (L.) Kunth leaf extract obtained by maceration method, then formulated as an anti-dandruff shampoo preparation starting with making a base consisting of sodium lauryl sulfate, cocamydopropyl betaine, polyquaternium 7, methyl paraben, sodium chloride, citric acid, menthol, rose perfume, and distilled water. Then added the extract of the leaves of the order each with a concentration of 1%, 3%, and 5%. The results obtained were then tested statistically with one way type ANOVA. Results:. The ethanol extract of suruh leaves can be formulated as an anti-dandruff shampoo preparation, and the ethanol extract of suruh leaf anti-dandruff shampoo preparations with a concentration of 5% has provided an effective inhibition against the growth of the fungus Pityrosporum ovale. Conclusion; The concentration of the ethanol extract of suruh leaves anti-dandruff shampoo which has an effective inhibitory activity against the growth of the fungus Pityrosporum ovale is in formula III with an inhibition zone of 14.2 mm.

Formulation of Mouth Mouth From Ethanol Extract of Carrot (Daucus Carota L.) Tubes as an Antifungal Against The Growth of Candida Albicans Diana, Vivi Eulis; Abadi, Hafizhatul
International Archives of Medical Sciences and Public Health Vol. 4 No. 2 (2023)
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v4i2.633

One of the causes of canker sores and bad breath is the presence of fungus in the oral cavity. This can be overcome by gargling using mouthwash. Research has been carried out on the formulation of mouthwash preparations from ethanol extract of carrot (Daucus carota L.) tubers as an antifungal against the growth of Candida albicans. Objectives: The aim of this study was to see the antifungal activity of carrot tuber extract mouthwash preparations. Methods: This research is a type of laboratory experimental research using the paper disc diffusion method on agar media to see the antifungal activity of carrot root extract mouthwash preparations. Carrot tuber extract mouthwash was made into four formulas, namely F0 (preparation without extract), F1 (5% carrot extract), F2 (15% carrot extract) and F3 (30% carrot extract). Evaluation of mouthwash preparations includes examination of organoleptic, pH, viscosity and stability. Results: indicate that mouthwash preparations can provide antifungal activity against the growth of Candida albicans. The diameter of the inhibition zone obtained at concentrations of 5% (2.9 mm), 15% (3.9 mm) and 30% (5.3 mm). All mouthwash formulations have a weak category of inhibitory power. The results of organoleptic evaluation, pH, viscosity and stability of mouthwash preparations gave good results, were stable and fulfilled the requirements for mouthwash preparations. Conclusion is that the ethanol extract of carrot root can be formulated into mouthwash and has weak antifungal activity.

Formulation And Activity Tests Of Anti Dandruff Shampoo Ethanol Extract Of Peperomia Pellucida (L.) Kunth Leaves On The Growth Of Pityrosporum Ovale Fungus Abadi, Hafizhatul; Eulis, Vivi
International Archives of Medical Sciences and Public Health Vol. 4 No. 1 (2023):
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v4i1.593

Shampoo is a cosmetic preparation used to clean hair. The leaves of Peperomia pellucida (L.) Kunth are one of the plants that can be used to get rid of dandruff. The plants contain alkaloids, saponins, tannins, hydroxylated sesquiterpenes, especially carotol and peppermint which have antifungal activity. Purpose; formulating anti-dandruff shampoo preparations containing suruh leaves, as well as evaluating shampoo preparations which include homogeneity, pH, organoleptic tests, foam height, viscosity, and irritation. Method; The research method used was an experimental method, namely Peperomia pellucida (L.) Kunth leaf extract obtained by maceration method, then formulated as an anti-dandruff shampoo preparation starting with making a base consisting of sodium lauryl sulfate, cocamydopropyl betaine, polyquaternium 7, methyl paraben, sodium chloride, citric acid, menthol, rose perfume, and distilled water. Then added the extract of the leaves of the order each with a concentration of 1%, 3%, and 5%. The results obtained were then tested statistically with one way type ANOVA. Results:. The ethanol extract of suruh leaves can be formulated as an anti-dandruff shampoo preparation, and the ethanol extract of suruh leaf anti-dandruff shampoo preparations with a concentration of 5% has provided an effective inhibition against the growth of the fungus Pityrosporum ovale. Conclusion; The concentration of the ethanol extract of suruh leaves anti-dandruff shampoo which has an effective inhibitory activity against the growth of the fungus Pityrosporum ovale is in formula III with an inhibition zone of 14.2 mm.

Formulation of Mouth Mouth From Ethanol Extract of Carrot (Daucus Carota L.) Tubes as an Antifungal Against The Growth of Candida Albicans Diana, Vivi Eulis; Abadi, Hafizhatul
International Archives of Medical Sciences and Public Health Vol. 4 No. 2 (2023)
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v4i2.633

One of the causes of canker sores and bad breath is the presence of fungus in the oral cavity. This can be overcome by gargling using mouthwash. Research has been carried out on the formulation of mouthwash preparations from ethanol extract of carrot (Daucus carota L.) tubers as an antifungal against the growth of Candida albicans. Objectives: The aim of this study was to see the antifungal activity of carrot tuber extract mouthwash preparations. Methods: This research is a type of laboratory experimental research using the paper disc diffusion method on agar media to see the antifungal activity of carrot root extract mouthwash preparations. Carrot tuber extract mouthwash was made into four formulas, namely F0 (preparation without extract), F1 (5% carrot extract), F2 (15% carrot extract) and F3 (30% carrot extract). Evaluation of mouthwash preparations includes examination of organoleptic, pH, viscosity and stability. Results: indicate that mouthwash preparations can provide antifungal activity against the growth of Candida albicans. The diameter of the inhibition zone obtained at concentrations of 5% (2.9 mm), 15% (3.9 mm) and 30% (5.3 mm). All mouthwash formulations have a weak category of inhibitory power. The results of organoleptic evaluation, pH, viscosity and stability of mouthwash preparations gave good results, were stable and fulfilled the requirements for mouthwash preparations. Conclusion is that the ethanol extract of carrot root can be formulated into mouthwash and has weak antifungal activity.

Formulation And Activity Tests Of Anti Dandruff Shampoo Ethanol Extract Of Peperomia Pellucida (L.) Kunth Leaves On The Growth Of Pityrosporum Ovale Fungus Abadi, Hafizhatul; Eulis, Vivi
International Archives of Medical Sciences and Public Health Vol. 4 No. 1 (2023)
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v4i1.593

Shampoo is a cosmetic preparation used to clean hair. The leaves of Peperomia pellucida (L.) Kunth are one of the plants that can be used to get rid of dandruff. The plants contain alkaloids, saponins, tannins, hydroxylated sesquiterpenes, especially carotol and peppermint which have antifungal activity. Purpose; formulating anti-dandruff shampoo preparations containing suruh leaves, as well as evaluating shampoo preparations which include homogeneity, pH, organoleptic tests, foam height, viscosity, and irritation. Method; The research method used was an experimental method, namely Peperomia pellucida (L.) Kunth leaf extract obtained by maceration method, then formulated as an anti-dandruff shampoo preparation starting with making a base consisting of sodium lauryl sulfate, cocamydopropyl betaine, polyquaternium 7, methyl paraben, sodium chloride, citric acid, menthol, rose perfume, and distilled water. Then added the extract of the leaves of the order each with a concentration of 1%, 3%, and 5%. The results obtained were then tested statistically with one way type ANOVA. Results:. The ethanol extract of suruh leaves can be formulated as an anti-dandruff shampoo preparation, and the ethanol extract of suruh leaf anti-dandruff shampoo preparations with a concentration of 5% has provided an effective inhibition against the growth of the fungus Pityrosporum ovale. Conclusion; The concentration of the ethanol extract of suruh leaves anti-dandruff shampoo which has an effective inhibitory activity against the growth of the fungus Pityrosporum ovale is in formula III with an inhibition zone of 14.2 mm.

Difference in Effectiveness Gel Dosage form Green Papaya (Carica papaya L.) Skin Ethanol Extract and Gel Dosage form Green Papaya Seed Against Cutibacterium acnes Bacteria Diana, Vivi Eulis; Abadi, Hafizhatul; Rumanti, Ruth Mayana; Andry, Muhammad
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.9330

Many things can cause acne, including stress, fatty foods, inappropriate or unsuitable makeup, and pollution. Cosmetics made from plants are safer to use. Papaya skin and seeds (Carica papaya L.) have antibacterial properties in the form of alkaloids, tannins, steroids, saponins, and flavonoids. This study aims to determine the comparison of the antibacterial power of young papaya skin ethanol extract gel and young papaya seed ethanol extract gel against Cutibacterium acnes bacteria. The research method is experimental with various formulas consisting of F0 (0%), F1 (11%), F2 (12%), and F3 (13%). The results of the study obtained antibacterial gel preparations from the three concentrations showed that the organoleptic test of the young papaya fruit skin ethanol extract gel preparation was light brown, blackish brown, dark blackish brown. The homogeneity test was homogeneous. The pH test was 5.9, 6.5, 7.0, and the seed ethanol extract gel preparation was light brown, dark brown, thick dark brown. The homogeneity test was homogeneous. Test pH 5.0, 5.6, 5.5, 5.1. The conclusion of this study is that the antibacterial effectiveness of young papaya fruit skin ethanol extract gel is greater than young papaya fruit seed ethanol extract gel at a concentration of 13% against Cutibacterium acnes bacteria.

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