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IMPACT OF EXTRACTION SOLVENTS AND FRACTIONATION TECHNIQUES ON PHENOLIC CONTENT AND ANTIOXIDANT POTENCY IN TURMERIC (CURCUMA DOMESTICA) Pratiwi, Denia; Wardaniati, Isna; Nasution, Azlaini Yus; Islami, Deri; Mardhiyani, Dini
Medical-Surgical Journal of Nursing Research Vol. 3 No. 2 (2024): Medical-Surgical Journal of Nursing Research
Publisher : Himpunan Perawat Medikal Bedah Indonesia (HIPMEBI) Regional Jawa Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70331/jpkmb.v3i1.45

Abstract

Turmeric is known to have many properties, one of which is as an antioxidant, the active substance which is considered to play a role in this activity is curcuminoid. Curcuminoids are part of the secondary metabolites of flavonoids and more specifically are phenolic. The purpose of this study was to examine the effect of the type of solvent on total phenolic levels with antioxidant activity in turmeric.  The method of the research is experimental laboratory has been carried out at the FMIPA UNRI laboratory in 2019. The turmeric rhizome which has been made as a simplicial is extracted using ethanol and graded fractionated using n-butanol and ethyl acetate solvents. Determination of total phenolic levels with Follin Ciocalteau reagents using a Microplate reader and gallic acid comparison while the value of antioxidant activity using the DPPH method. The result will be analyzed descriptively. Based on the results of the study it was found that there is a solvent effect on total phenolic content and antioxidant activity seen from IC50 values and different total phenolics, namely in determining the total phenolic content of turmeric (Curcuma domestica) successively ethanol extract, water fraction, ethyl acetate fraction, fraction n-butanol of 90.1364; 22,0303; 45,2397; 20,9697 mg / g (GAE) and on the measurement of antioxidant activity the IC50 value was 65.7506 µg / mL; 384,2774 µg / mL; 64,6012 µg / mL; 834,3335 µg / mL with smaller activity compared to the antioxidant activity of vitamin C which is 7.27624 µg / mL.
Antioxidant Activity of Peel-off Mask from Pangasius Catfish Gelatin (Pangasius hypophthalmus) with Astaxanthin Yus Nasution, Azlaini; Sari, Novia Novita; Fauzana, Annisa
Pharmacon: Jurnal Farmasi Indonesia Volume 21, No 2 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i2.6665

Abstract

Peel-off face masks are a type of mask that contains elastic materials such as gelatin, making them easy to apply and remove. These peel-off masks are applied to the face by spreading them to form a thin, transparent film layer. Pangasius catfish gelatin serves as the gelling agent in the formulation of the peel-off mask, and astaxanthin is added as an antioxidant. Astaxanthin is a carotenoid pigment with a molecular structure similar to β-carotene, exhibiting stronger antioxidant activity compared to β-carotene in neutralizing free radicals. The purpose of this research is to determine the antioxidant activity of peel-off gel masks made from pangasius catfish (Pangasius hypophthalmus) gelatin supplemented with astaxanthin using the DPPH method. Astaxanthin extract was used as the active ingredient in the production of the peel-off gel mask, with an astaxanthin extract concentration of 0.5%. The results of the antioxidant activity test for the peel-off gel mask made from pangasius catfish gelatin supplemented with astaxanthin yielded an IC50 value of 7572.84 µg/mL, while the IC50 value for the comparative mask (Brightening lemon blackhead brand) was 5045.74 µg/mL. These results indicate that the mask produced has lower antioxidant activity compared to the comparative masks available in the market.
Pemanfaatan Terapi Komplementer Sebagai Upaya Penanganan Kesehatan Reproduksi Dan Edukasi Seks Pada Remaja Putri Sartika, Wiwi; Yusmaharani, Yusmaharani; Nasution, Azlaini Yus; Marwan, Deinike Wanita
Jurnal Pengabdian Masyarakat: Pemberdayaan, Inovasi dan Perubahan Vol 4, No 6 (2024): JPM: Pemberdayaan, Inovasi dan Perubahan
Publisher : Penerbit Widina, Widina Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59818/jpm.v4i6.890

Abstract

Understanding and awareness of reproductive health and rights among adolescents is still low, and some of these understandings are even incorrect. This is because society and families are still reluctant to discuss reproductive issues openly within the family and community. Discussion of reproductive health from the perspective of traditional, cultural and religious values which consider adolescent reproductive health issues as taboo is actually more popular compared to understanding the importance of knowing and properly discussing adolescent reproductive health issues. Accurate and correct knowledge of adolescents about reproductive health issues is very important to support efforts to improve the reproductive health status of adolescents and control birth rates through regulating the marriage age rate. This service to the community is providing education and counseling related to reproductive health and sex education for adolescent girls by complementary approach at Pekanabru Muhammadiyah High School so that young women know how to handle reproductive health problems using a complementary approach. In this community service, Stage I Preparation is handling Reproductive Health and sex education, Stage II Implementation is delivering material about handling Reproductive Health and sex education.  From the results of the presentation of material and questions and answers from 84 young women, there were still many who did not understand reproductive health. Conclusion: There is still a lack of information related to reproductive health which affects the knowledge of young women.ABSTRAKPemahaman dan kesadaran tentang hak dan kesehatan reproduksi pada remaja masih rendah, bahkan beberapa diantaranya pemahaman tersebut tidak tepat. Hal ini dikarenakan masyarakat dan keluarga masih enggan untuk membicarakan masalah reproduksi secara terbuka dalam keluarga dan masyarakat. Pembahasan kesehatan reproduksi dari sudut nilai-nilai adat, budaya, dan agama yang menganggap masalah kesehatan reproduksi remaja sebagai hal yang tabu justru lebih popular dibanding dengan pemahaman pentingnya untuk mengetahui dan mendiskusikan secara benar tentang masalah kesehatan reproduksi remaja. Pengetahuan remaja yang secara tepat dan benar tentang masalah kesehatan reproduksi sangat penting untuk mendukung upaya meningkatkan status kesehatan reproduksi remaja dan pengendalian angka kelahiran melalui pengaturan angka usia kawin. pengabdian kepada masyarakat ini adalah Memberikan Edukasi dan penyuluhan terkait kesehatan reproduksi dan edukasi seks pada remaja puteri dengan pendekatan komplementer di SMA Muhammadiyah Pekanabaru sehingga remaja puteri mengetahui bagaimana cara penanganan jika mengalami permasalahan kesehatan Reproduksi dengan pendekatan komplementer. Dalam pengabdian masyarakat ini Tahap I Persiapan yaitu penanganan Kesehatan Reproduksi dan edukasi seks, Tahapan II Pelaksanaan yaitu penyampaian materi tentang penanganan Kesehatan Reproduksi dan edukasi seks.  Dari hasil penyampaian materi dan tanya jawab dari 84 remaja puteri masih banyak yang kurang memahami tentang kesehatan reproduksi. Kesimpulan : Masih kurangnya informasi terkait kesehatan reproduksi sehingga mempengaruhi pengetahuan remaja puteri.