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Florentinus Dika Octa Riswanto
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INDONESIA
Jurnal Farmasi Sains dan Komunitas
Published by Universitas Sanata Dharma
ISSN : 16935683     EISSN : 25277146     DOI : https://doi.org/10.24071/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 247 Documents
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Patients with COVID-19 Critical Illness Have a Significantly Higher Systemic Immune-Inflammatory Index on Admission Fenty Fenty; Dita Maria Virginia; I Made Adi Ananda Putra; Devie Kristiani; Lisa Kuniasari
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 1 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005150

Abstract

The severity of Coronavirus Disease-2019 (COVID-19) has been correlated to the massive inflammatory response. Patients with COVID-19 have a higher inflammatory marker. The Systemic Immune-Inflammation Index (SII) can be considered as an indicator of the immune-inflammatory status. Many studies stated that SII could significantly indicate the severity of COVID-19. This research aimed to explore the admission SII score and its association with the severity of hospitalized patients with COVID-19. It was a cross-sectional observational study. Data were collected retrospectively from the electronic medical records (ERM) and Laboratory Information System (LIS).  The severity of COVID-19 and laboratory data on admission were analyzed. There were 180 patients (49.4% males and 50.6% female) with COVID-19 included in this research. Of these 180 patients, 22. 8% were categorized as mild, 18.9 moderate, 37.2% severe, and 21.1% were critical cases. Patients with critical illness had significantly higher SII scores than other groups with a p-value 0.05. SII on admission could be a noticeable predictor of the occurrence of critically ill COVID-19 patients.
Gold Nanoparticles with Natural Ingredients as Anti-Aging: A Systematic Review Agita Dyah Permatasari; Yandi Syukri; Sista Werdyani
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 1 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.004374

Abstract

Aging is a natural process characterized by physiological skin changes. It starts to appear when individuals are in their thirties, making it necessary to use anti-aging products with natural ingredients which are safe even though the penetration is relatively low into the skin. Natural ingredients that can be used are antioxidants that can inhibit aging and can act as bioreductants on gold nanoparticles. Gold nanoparticles can increase penetration into the target cells because of their small size with large surface area. This review article aimed to collect data relating to the development of gold nanoparticles with natural ingredients as anti-aging agents. This review searched through the PubMed and ScienceDirect databases with such keywords as aging, anti-aging, plant extract, antioxidants, and gold nanoparticles. The inclusion criteria were articles in English, available in a full-text version, and published in the last 10 years. Research on the use of natural ingredients as anti-aging agents found that natural ingredients perform better than chemical comparators. Gold nanoparticles are also reported to have been widely used in anti-aging products. Their activity is even better given the low IC50 value and a higher percentage of inhibition compared to those of the extracts without nanoparticle modification. It is reported that gold nanoparticles with natural ingredients as anti-aging agents have a better effect as opposed to purely natural ingredients.
Development and Evaluation of Microemulsion-Based Sunscreen Cream Containing Lycopene from Tomato (Solanum lycopersicum L.) Ritha Pratiwi; Nandiska Maladjili; Evi Sulastri; Yusriadi Yusriadi; Nuur Aanisah; Armini Syamsidi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 1 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.003807

Abstract

This study aimed to formulate and determine the sun protection factor (SPF) of sunscreen made from tomato lycopene microemulsion creams. Lycopene was used as the active ingredient with varying concentrations in each formula, namely F1 5%, F2 7.5%, and F3 9%. The preparation of each formula was evaluated by conducting the globule size, polydisperse index, organoleptic test, homogeneity test, pH test, spreadability test, viscosity test, and determination of SPF value. The average globule size was 119 nm which had a uniform size distribution. The physical characteristics test of the cream preparations showed the three had a bright yellow color and lacked odor. The pH test results were 3.2 ± 0.12, 5.54 ± 0.25, 6.48 ± 0.22 for F1, F2, F3, respectively. Viscosity test results were F1 40,893.33 cPs, F2 41,746.67 cPs, and F3 43,106.67 cPs. The values obtained from the dispersion test were F1 6.71±0.63, F2 5.58±0.15, and F3 4.81±0.11. Moreover, F3 with a concentration of 9% tomato lycopene microemulsion met the acceptance criteria for all of the physical properties including low viscosity to promote good spreadability, pH that does not irritate the skin, aesthetic appeal, small particle size, and non-odorous and an SPF value of 4.9. The obtained microemulsion-based sunscreen cream exhibited a good physical property of lycopene besides showing sufficient SPF value.
In Vitro and In Vivo Anti Hyperglycemic Evaluation of Sterculia quadrifida Bark through The Inhibition of Alpha Glucosidase Jeffry Julianus; Maria Dewi Puspitasari Tirtaningtyas Gunawan-Puteri; Radhita Tyastu Puteri Wiwengku; Agustina Setiawati; Phebe Hendra
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 1 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005153

Abstract

Data from the International Diabetes Federation revealed annual increases in the prevalence of diabetes mellitus, which require special attention. Implementation of the ‘back to nature’ trend presents opportunities to overcome this problem. As a medicinal plant, Faloak is widely used by people in Nusa Tenggara Timur, Indonesia. This study aimed to evaluate in vivo and in vitro anti-hyperglycemic activity of the bark of Sterculia quadrifida, known as Faloak. In vivo evaluation used sucrose-induced male mice. Measurements of glucose level employed a glucometer and data were analyzed statistically. Demonstrating anti-hyperglycemic activity of the bark of Faloak decoct, results showed doses 1.67 and 3.3 g/kg BW reduced glucose levels by 62.2% and 56.9%, respectively. In vitro examination of Faloak decoct at various concentrations used alpha glucosidase (sucrose) enzymatic reaction. Results of in vitro examinations demonstrated of Faloak bark decoct inhibited alpha glucosidase (sucrose) activity by 42.09 ± 4.39%. Further testing on humans is needed to confirm these findings.
E-Health Literacy and Adherence to Health Protocols Among Self-Quarantined Patients with COVID-19 in a Sub-district in West Java Hesty Utami Ramadaniati; Sondang Khairani; Nurul Azizah
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 1 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.004176

Abstract

During the Coronavirus Disease-2019 (COVID-19) pandemic, valid information was crucial and electronic health literacy (EHL) plays a significant role in public adherence to health protocols. This study aimed to evaluate the pattern of COVID-19 information-seeking, and the association between EHL, COVID-19 knowledge, and health protocol adherence among patients with COVID-19 during self-quarantine. Data were collected through an online survey sent to self-quarantined COVID-19 patients during March – December 2020 in a sub-district in West Java. Spearman tests were used to evaluate the relationship between EHL with COVID-19 knowledge, and EHL with health protocol adherence. There were 56 respondents with more than half being female (58.9%), university graduates (64.3%) and having good health status level (57.1%). Social media were the commonest online sources. During self-isolation, the frequency of Internet use increased (i.e., every day) with information on vitamins and supplements as the most commonly searched. Respondents had high scores on EHL (mean= 20.0), knowledge (mean = 8.89/10, SD = 1.796), and adherence (mean = 26.98/30, SD = 3.066). This study found significant relationships between EHL and knowledge (p-value = 0.001, r = 0.436), and the adherence (p-value = 0.011, r = 0.339). In conclusion, EHL had a modest influence on COVID-19 knowledge and minor relationship with adherence to health protocols among self-quarantined patients with COVID-19.
Socialization of TB Zero Program During The COVID-19 Pandemic for Residents of Islamic Center Residences in Kediri Assolychatu Jaroh; Titien Siwi Hartayu
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 1 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.004557

Abstract

Tuberculosis (TB) problem is still a challenge for Indonesia today. The World Health Organization reports that Indonesia is the third country with the highest TB burden globally. All component of society must take a role in dealing with the global TB problem to achieve Zero TB in 2050. As the implementation, the Pesantren 2 Primary Health Care conducted socialization in the Wali Barokah Islamic Center, Kediri City. Socialization about knowledge to residents of Islamic Center, this study aims to determine the essential characteristics of Islamic Center residents against TB disease. Questionnaires related to knowledge were filled out before and after explanation using PowerPoint and leaflet media. By using purposive, sampling method obtained 100 respondents. The survey results showed a significant increase in the knowledge of Islamic Center residents about TB disease after socialization in terms of signs and symptoms of the disease (p 0.02), modes of transmission (p 0.02), and methods of prevention of transmission (p 0.01). Negative attitudes are still visible by stigmatizing TB sufferers from being ostracized (62.7%). The majority of subjects will go to health facilities (6.9%), but subjects still choose not to go for treatment (68%). The presentation of material about TB leads to reduce the burden of TB disease in TB endemic communities by modifying attitudes and behavior.
Curcumin Transethosome Gel: Anti-inflammatory Activity Test in Carrageenan-Induced Sprague Dawley Rat Amalia, Anisa; Efendi, Kriana; Novianti, Amelia
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005618

Abstract

Curcumin has anti-inflammatory activities, and is formulated into the transethosome (TE) system to improve penetration. The TE system's stability can be increased by incorporating it into a gel dosage form. This study aims to determine the anti-inflammatory activities of curcumin TE gel. Curcumin TE gel was produced in 3 compositions, each having a curcumin content of 10 mg (F1), 40 mg (F2), or 160 mg (F3). On TE gels, organoleptic, viscosity, pH, particle size, and zeta potential were evaluated. The test animals were divided into five groups for anti-inflammatory activity testing. A 1% carrageenan solution was used to induce edema in the animals, and the volume of edema was measured for comparison with p0.05set as significant difference. Curcumin TE gel's physical properties showed a yellow and homogenous gel with viscosity values of 31.173 – 33.626 cPs, pH 4.75 – 4.84, particle size 208.3 – 319.4 nm, and zeta potential (-) 40.03 – (-) 51.12 mV. On anti-inflammatory tests, the edema volume in the group given curcumin TE gel decreased in the 270th minute. According to statistical analysis, the test group had a significant difference (p 0.05) from negative controls and no significant difference (p 0.05) from positive controls in F1 and F2 anti-inflammatory activity. According to these results, the curcumin TE gel exhibited anti-inflammatory activity equivalent to the positive control, while F3 had anti-inflammatory activity better than the positive control. 
Beneficial Fruit-Derived Phytochemicals in Treating Alzheimer’s Disease – A Review Yurida Ni'ma Annisa; Vania Amanda Samor; Muthi Ikawati; Nunung Yuniarti
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 2 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.004491

Abstract

Fruits, as a major source of nutrition have been investigated for their emerging evidence of several neuroprotective activities beneficial to Alzheimer’s disease (AD). This paper discusses recent evidence suggesting several fruit-derived bioactive substances that possess anti-AD activity. The original articles from 2011–2022 were collected from Pubmed and Scopus with related keywords and filtered. Several fruit constituents have shown significant inhibitory action against β-amyloid and tau hyperphosphorylation, either directly or indirectly via secretase inhibition. Some were also found to be cholinesterase inhibitors with specific antioxidative roles, disruptors of the neuroinflammation system, and promoters of neurogenesis and the neurogenic process. Many fruit phytochemicals remarkably alter the capability defects shown in AD animal models, such as catechin, nobiletin, and alpha-mangostin. Therefore, further investigations exploring a certain bioactive isolate or formulated dosage form and its mechanism of action are necessary to provide effective prevention and supplementary treatment for AD.
COVID-19 Vaccine Acceptance in A Private Islamic Boarding School, West Nusa Tenggara Siti Rahmatul Aini; Iman Surya Pratama; Raisya Hasina; Candra Eka Puspitasari; Ni Made Amelia Ratnata Dewi; Muhammad Abdurrahman Fardiaz; Nurmayanggi Aulia Safitri; Shifa Hasanah; Yazid Maula Arzaqi; Khairun Nissa
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 2 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.006418

Abstract

The COVID-19 vaccination program began in Indonesia in 2020, but it is still unknown how well it has been received by particular communities in places like the West Nusa Tenggara region's Islamic boarding schools. This research aimed to identify the characteristics and factors that contribute to the COVID-19 vaccine's acceptance at the Nurul Islam Sekarbela Islamic Boarding School. In August 2022, a cross-sectional survey was conducted on a stratified random sample of chosen boarding school students using a validated questionnaire. Data on demographic factors, COVID-19 history, religious acceptance, and opinions were all examined descriptively. A total of 124 students, or 62%, gave their informed permission. Based on the findings, it was determined that the Nurul Islam Sekarbela Islamic Boarding School's level of acceptance of the COVID-19 vaccine is still considered low (35%) and in doubt (65%). Acceptance of vaccines is mostly influenced by efficacy, safety, and family recommendations. Acceptance of vaccines is impeded by the dominant fatalistic religious mindset.
Success Factors in Improving Patients’ Adherence to Tuberculosis Treatment Program: Case Study in Sleman, Yogyakarta, Indonesia Mario Yedi Mau; Titien Siwi Hartayu
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 20, No 2 (2023)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005770

Abstract

Improving patients’ adherence to treatment programs is important for the success of tuberculosis (TB) treatment. The study aims to identify the underlying factors of TB treatment program success. A qualitative approach, i.e., an in-depth interview, and the purposive sampling method in selecting respondents were used to conduct this study. There are 15 persons involved, i.e., 3 persons each: pharmacists as providers, TB programmers, medicines supervisor (MS), TB cadres as supporters, and recovered TB patients as actors (17 years old and over). The data obtained were analyzed using the triangulation method (providers, actors, and supporters). The results of the study show that the family's role is very important in MS by taking medicines from primary health care and giving medicines on time. TB counselors play a role in monitoring the treatment program and making occasional home visits to motivate patients to recover. TB  programmers and pharmacists play a role in providing patients’ education and MS, as well as monitoring medication-taking schedules and medical check-ups. Patients play a role in motivating themselves to get back to work soon. In conclusion, the underlying factors in TB treatment program success are the discipline of providers, supervisors, supporters, and patients’ motivation.

Page 17 of 25 | Total Record : 247

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