cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Chairunisa Ayu Saputri
Contact Email
jurnalmedfarm@gmail.com
Phone
+6287859041641
Journal Mail Official
jurnalmedfarm@gmail.com
Editorial Address
Jl. Batoro Katong No. 32 Ponorogo
Location
Kab. ponorogo,
Jawa timur
INDONESIA
Medfarm: Jurnal Farmasi dan Kesehatan
Published by Akademi Analis Farmasi dan Makanan Sunan Giri Ponorogo
ISSN : 23548487     EISSN : 27159957     DOI : -
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology Public Health
Jurnal MEDFARM merupakan terbitan dari lembaga jurnal dibawah naungan Lembaga Penelitian dan Pengabdian Masyarakat (LP2M) Akademi Analis Farmasi dan Makanan Sunan Giri Ponorogo. Topik atau pembahasan dari Jurnal MEDFARM lebih terfokus pada bidang Farmasi, Obat Tradisional, Makanan, Minuman dan Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 154 Documents
 9   10   11   12   13 
OPTIMIZATION OF GREEN SYNTHESIS OF GOLD NANOPARTICLES USING CHILI FRUIT EXTRACTS (Capsicum Sp.) Oktavia, Anggraeni In; Mastuti, Retno; Rosyidah, A’liyatur; Arumingtyas, Estri Laras
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.502

Abstract

The use of plant extracts as reductants in green synthesis of gold metal nanoparticles (AuNPs) requires optimal conditions of temperature, extract concentration and pH. The objective of this research is to identify the optimal synthesis conditions for producing gold nanoparticles (AuNPs). The reducing agents employed are extracts from three varieties of chili peppers: Katokkon, Cakra Hijau, and Paprika Merah. Variations of plant extract concentrations of 10%, 15%, and 20%, incubation temperatures of 25°C, 37.5°C, and 50°C, and pH levels of 5, 7, and 9. The optimization formula design was determined using Box-Behnken, Design Expert version 13.0. The formation of AuNPs was indicated by a change in the color of the solution from yellow to pink to purple. Surface plasmon resonance was observed in the range of 200-800 nm using a microplate reader. Chili, Katokkon, Cakra Hijau and Red Paprika extracts were able to synthesize Au into AuNPs. The optimal formula for synthesizing AuNPs using Katokkon and Red Paprika extracts at a concentration of 10% while Ckra Hijau at a concentration of 15%. The incubation temperature used was 37.5°C for Katokkon extract and 25°C for Cakra Hijau and Red Pepper extract. The pH level used for the synthesis of AuNPs was pH 5 for all chili pepper extracts.
The Effect of Giving Red Ginger Jelly an Dysmenorrhea Pain in Female Students at Junior High School in Samarinda Lushinta, Lidia; Ratanto, Ratanto; Jasmawati, Jasmawati; Yesi, Pina; Haloho, Cristinawati B/R; Sinaga, Elisa Goretti; Sholikah, Imroatus; Nurachma, Evy; Patty, Fara Imelda Theresia
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.504

Abstract

Adolescence is a period of growth and developmental change, both biologically, cognitively, and psychosocially, called puberty. A sign that a teenager is experiencing puberty is that she will experience menstruation. Menstrual pain, commonly known as dysmenorrhea, occurs during menstruation. Dysmenorrhea is pain during menstruation that is felt in the lower abdomen to pain in the waist. One treatment with non-pharmacological therapy to reduce dysmenorrhea pain during menstruation is the administration of Red Ginger Jelly, which contains essential oils and aloricin, which can inhibit prostaglandin hormones to decrease pain. To determine whether Red Ginger Jelly affects dysmenorrhea pain in junior high school students in Samarinda. One group with a pre- and post-test design comprised students in 7th, 8th, and 9th grades of Junior High School in Samarinda who experienced primary dysmenorrhea pain. The non-probability sampling technique with Purposive Sampling included 18 individuals. Data were processed by univariate and bivariate analyses using the Shapiro–Wilk and Wilcoxon tests. The results of the study showed that there was an effect of giving Red Ginger Jelly on dysmenorrhea pain in students at Junior High School in Samarinda (p-value 0.000) with p value < 0.05. Red Ginger Jelly reduced primary dysmenorrhea pain in junior high school students in Samarinda.
Ethnopharmaceutical Study of Medicinal Plants in Sumbersuko District, Lumajang Regency Seran, Ivan Charles S Klau Charles; Utami, Wahyu Putri; Ningsih, Arista Wahyu; Rahmawati, Dewi; Fevi, Bella; Ambari, Yani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.509

Abstract

There are approximately 400 distinct ethnic groups in Indonesia (ethnic and sub-ethnic). Traditional medical practices are one example of the kinds of knowledge that have been handed down from one generation to the next in every nation, tribe, and subgroup within those nations. The people who live in the Lumajang Regency continue to have faith in the efficacy of traditional medicine. The practice of traditional medicine or shamans who treat residents around their residences in a number of districts in Lumajang, one of which is the Sumbersuko district, is evidence that this is the case. In the Sumbersuko District, there are a total of eight speakers who continue to uphold traditions related to the use of natural materials in medical practice. Interviews and questionnaires are being used as tools for the descriptive methodology that underpins this research project. According to the findings of this research, there are 37 different species of plants that are used as traditional medicine by the local community in the Sumbersuko District. These plants are categorized into 26 different families, with the Zingiberaceae family containing the most types of plants, including as many as 5 different species of plants. According to the findings of this research, the members of the community in the Sumbersuko District utilize the following plant parts: leaves, rhizomes, bulbs, fruits, skin, seeds, stems, flowers, sap, and all other plant parts. The leaf is the most commonly used component of the plant. To prepare plants for use, they are typically boiled, grated, ground, kneaded, and squeezed before being put to direct use.Keywords: consist of 3-5 words or phrases represent the focus of writing.
Application of Pharmaceutical Care Standards in the Drug Storage Phase at Pharmacy X Lingsar, West Lombok Regency, in Accordance with the Indonesian Ministry of Health Regulation Number 17 of 2024 Hera, Alma
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.518

Abstract

Pharmacies, according to regulations, are vital locations within the healthcare service system. The aim of this research is to determine the implementation of pharmaceutical service standards at Pharmacy X Lingsar, West Lombok Regency, specifically during the drug storage phase. This study employs a descriptive observational method, involving direct observation of the storage system using a checklist at Pharmacy X Lingsar, located in Lingsar District, West Lombok Regency. The research findings indicate the following compliance rates: Spatial Arrangement 83.33%, Drug Organization 83.33%, Stock Card Recording 100%, and Drug Quality Monitoring 100%. These results suggest that drug storage practices at Pharmacy X Lingsar do not fully meet the standards outlined in the Ministry of Health Regulation of the Republic of Indonesia No. 17 of 2024 and the National Agency of Drug and Food Control of the Republic of Indonesia (BPOM RI) of 2018.
ACUTE CENTRAL TYPE FACIAL PARALYSIS AS A RARE MANIFESTATION OF CEREBRAL ARTERY STROKE MEDIA Kandisa, Dayinta Drasti
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.521

Abstract

Acute central type facial paralysis is a rare manifestation of cerebral artery media stroke (MCA) that is often misdiagnosed as Bell's palsy. This article discusses the case of a 40-year-old woman with a swollen face to the right and a deviation of the tongue to the left without weakness of the extremities, as well as hypertension at onset. The diagnosis of Bell's palsy is questionable due to the involvement of nerve XII and vascular risk factors. Lesions in the primary motor cortex or corticobulbar tract, supplied by a specific branch of MCA, are the main cause of this condition. About 3-7% of acute MCA strokes show central-type facial paralysis as the main symptom. Management includes the administration of antiplatelets, while corticosteroids are not recommended in ischemic stroke. The prognosis of this case tends to be good compared to MCA stroke with extensive neurological deficits, but the risk of recurrence is high if vascular risk factors are not controlled. This study confirms the importance of vigilance against atypical manifestations of stroke, especially in patients with hypertension or other vascular risk factors. Proper diagnosis, appropriate management, early rehabilitation, and secondary prevention play a major role in improving clinical outcomes and preventing stroke recurrence.
Evaluation of Antibiotic Utilization Patterns in Community-Acquired Pneumonia Inpatients Using ATC/DDD and DU 90% Methods at Taman Husada Bontang Regional General Hospital in 2024 Lawin, Handratin; Geografi, Liniati
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.522

Abstract

Community-acquired pneumonia (CAP) represents an acute infectious inflammatory condition affecting the lung parenchyma, typically contracted in non-hospital settings. Antibiotic therapy serves as the primary treatment modality for CAP. This investigation employs a dual methodological approach: quantitative assessment through the Defined Daily Dose (DDD) metric and qualitative evaluation utilizing the Drug Utilization 90% (DU 90%) analysis. The study objectives focus on characterizing antibiotic consumption patterns among CAP patients at Taman Husada Bontang Regional General Hospital during 2024, employing both ATC/DDD and DU90% analytical frameworks. This quantitative descriptive research utilized retrospective data collection from medical records of CAP inpatients admitted between January and June 2024. Following comprehensive screening, 83 eligible patient records were included for analysis. Data processing involved descriptive statistical methods with Microsoft Excel for tabular presentation of findings. Demographic analysis revealed a homogeneous age distribution (100% within 18-39 years) with male predominance (59%). Quantitative evaluation identified Ceftriaxone as the most frequently prescribed antibiotic (42.5 DDD/100 treatment days). The DU 90% analysis further delineated the therapeutic landscape, with Ceftriaxone (52.9%), Levofloxacin (23.5%), Azithromycin (11.1%), and Ceftazidime (5.3%) constituting the predominant therapeutic agents.
ANTIFUNGAL EFFECT OF TURMERIC EXTRACT (Curcuma domestica) IN LIQUID SOAP FORMULATION AGAINST THE GROWTH OF Malassezia furfur ATCC 14521 Mursyida, Eliya; Tanjung, Anellia Putri
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.523

Abstract

Turmeric (Curcuma domestica) has been identified as a potential natural antifungal agent due to its curcuminoids and essential oils. Malassezia furfur, a lipophilic fungus, is commonly found on human skin but can become pathogenic, causing Pityriasis versicolor. This study aimed to evaluate the antifungal activity of turmeric extract in a liquid soap formulation against Malassezia furfur. A post-test only with control group design was used, employing the well-diffusion method to assess antifungal efficacy. Turmeric extract was incorporated into liquid soap at concentrations of 10%, 15%, and 20%, with positive (commercial antifungal soap) and negative (soap base) controls. The inhibition zones were measured using a vernier caliper, and data were analyzed using One-Way ANOVA followed by post hoc Bonferroni testing. Results showed that all formulations met the Indonesian National Standards (SNI). The highest inhibition zone was observed at 20% concentration (17,46 mm), while the lowest was at 10% concentration (15,80 mm). ANOVA analysis confirmed significant differences between groups (p < 0,05). The study concludes that turmeric extract in liquid soap formulations demonstrates antifungal activity against Malassezia furfur and has potential as a natural alternative to synthetic antifungal agents.
Antibiotic Use in Pediatric Pharyngitis at Juanda Samarinda Public Health Center from January-December 2023 -, Mardiana -; Geografi, Liniati; Simanullang, Raymon
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.529

Abstract

Pharyngitis is an infection or inflammation of the pharyngeal (throat) region, primarily caused by bacteria and viruses. The most common bacterial cause is Group A Streptococcus. Management of bacterial pharyngitis involves the use of antibiotics aimed at eradicating the causative pathogen. Quantitative analysis of antibiotic use can be conducted using the Defined Daily Dose (DDD) method, which is useful for assessing both the pattern and volume of drug consumption. This study aims to quantify the use of antibiotics in pediatric pharyngitis patients using the ATC/DDD method at Juanda Samarinda Public Health Center in 2023. This research is classified as a descriptive quantitative study and employs a non-experimental, retrospective design. Data were collected from antibiotic usage reports and medical records of pediatric pharyngitis patients treated in 2023. Data processing was performed using descriptive and quantitative analysis, with all results processed using Microsoft Excel 2019 and presented in tabular format. Based on the findings, the antibiotic with the highest usage in pediatric pharyngitis patients at Juanda Samarinda Public Health Center was Amoxicillin, with an average of 38.5 DDD/1,000 patient-days (KPRJ), while the lowest was Cefadroxil, with an average of 4.9 DDD/1,000 patient-days (KPRJ).
Optimization and characteristics of selfnanoemulsifying drug delivery system (snedds) components diclofenac sodium fractional method factorial design (ffd) setiyawan, ferdinta; Herman, Herman; Imba, Farhan
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.531

Abstract

S SelfNanoEmulsifying Drug Delivery System (SNEDDS) is a drug delivery system designed to increase the solubility and bioavailability of active substances that are difficult to dissolve in water, such as sodium diclofenac. Diclofenac sodium SNEDDS was optimized using FFD. Variables: oil, surfactant, co-surfactant, and mixing time. Responses: droplet size, PDI, and drug loading. Evaluation: DLS, UV-Vis, and stability tests. This study aims to optimize the formulation of SNEDDS sodium diclofenac using the Fractional Factorial Design (FFD) method to obtain a formula with the best characteristics. The main parameters analyzed include entrapment efficiency (%), vesicle size (nm), zeta potential (mV), and polydispersity index (PDI). The results showed that Formula F12 was the best formula with the highest desirability value (0.96). This formula has an entrapment efficiency of 92.5%, the smallest vesicle size (118 nm), and high electrostatic stability with a zeta potential of -36.0 mV and a low polydispersity index (0.20). In addition, Formulas F8 and F4 are also included in the optimum category with desirability values of 0.94 and 0.92, respectively. With small vesicle size and high stability, this SNEDDS formula has the potential to increase the bioavailability of diclofenac sodium, so it can be further developed as a more effective drug delivery system in pharmaceutical applications.
Impact of Side Effects on Adherence in Drug-Resistance Tuberculosis Treatment at RSD dr. Soebandi Jember Poerwahyuningrum, Neny; Fajrin, Fifteen Aprilla; Rahardjo, Angga Mardro; Prasetyowati, Irma; Arwi, Khoiriyatul Muhlishoh; Machlaurin, Afifah
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.537

Abstract

Tuberculosis (TB) is the leading cause of death from infectious disease worldwide. Patient adherence to treatment is crucial for therapy which side effects of tuberculosis treatment are a significant factor affecting compliance. This study aims to analyze the impact of side effects from anti-tuberculosis drugs on the medication adherence of Drug Resistant Tuberculosis patients (DR-TB) at RSD dr. Soebandi in Jember. This study was a retrospective cohort observational that included 245 DR-TB patients register at the dr. Soebandi Hospital from January 2021-December 2023. The electronic medical records, web-based tuberculosis information systems (SITB), and data filling sheets was used. The Proportion of Days Covered (PDC) method was used to evaluate the medication adherence. Data analysis was conducted in SPSS 27.0. Ten patients were excluded due to HIV comorbidities, resulting a final sample of 235 patients. The findings revealed that 53.6% of patients were non-adherence. The three most common types of side effects were gastrointestinal (43.4%), musculoskeletal (29.8%) and skin-related side effects (16.6%). The multivariate logistic regression showed that adherence was significantly reduced by the presence of side effects (aOR: 0,153; 95%CI 0,052-0,448), the number of side effects >2 types (aOR: 0,290; 95%CI 0,101-0,837), and the musculoskeletal-related side effects (aOR: 0,441; 95%CI 0,201-0,972).

Page 11 of 16 | Total Record : 154

 9   10   11   12   13 

Filter by Year

2019 2025


Reset
Filter By Issues
All Issue Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan Vol 13 No 2 (2024): Medfarm: Jurnal Farmasi dan Kesehatan Vol 13 No 1 (2024): Medfarm: Jurnal Farmasi dan Kesehatan Vol 12 No 2 (2023): Medfarm: Jurnal Farmasi dan Kesehatan Vol 12 No 1 (2023): MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan Vol 11 No 1 (2022): MEDFARM: Jurnal Farmasi dan Kesehatan Vol 10 No 2 (2021): MEDFARM: Jurnal Farmasi dan Kesehatan Vol 10 No 1 (2021): MEDFARM: JURNAL FARMASI DAN KESEHATAN Vol 9 No 2 (2020): MEDFARM : JURNAL FARMASI DAN KESEHATAN Vol 9 No 1 (2020): MEDFARM : JURNAL FARMASI DAN KESEHATAN Vol 8 No 2 (2019): MEDFARM : JURNAL FARMASI DAN KESEHATAN Vol 8 No 1 (2019): MEDFARM : JURNAL FARMASI DAN KESEHATAN More Issue