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Medfarm: Jurnal Farmasi dan Kesehatan
Published by Akademi Analis Farmasi dan Makanan Sunan Giri Ponorogo
ISSN : 23548487     EISSN : 27159957     DOI : -
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology Public Health
Jurnal MEDFARM merupakan terbitan dari lembaga jurnal dibawah naungan Lembaga Penelitian dan Pengabdian Masyarakat (LP2M) Akademi Analis Farmasi dan Makanan Sunan Giri Ponorogo. Topik atau pembahasan dari Jurnal MEDFARM lebih terfokus pada bidang Farmasi, Obat Tradisional, Makanan, Minuman dan Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 154 Documents
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Performance Analysis of the Pharmacy Installation Dr Harjono Ponorogo Regional General Hospital in 2023 Based on the Balanced Scorecard Method Yustyananingrum, Nora; Wijayanti, Tri; Harsono, Samuel Budi
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.575

Abstract

Background: RSUD Dr. Harjono Ponorogo is a referral health facility in the Ponorogo district. So far, its performance measurement has only focused on financial aspects. Therefore, a more comprehensive approach is needed using the Balanced Scorecard method which includes four main perspectives, namely financial perspectives, internal business processes, customers, growth and learning Objectives: To determine the performance of IFRS RSUD dr Harjono balanced scorecard method using four perspectives. Methods: Descriptive research method with a combination approach involved all IFRS employees and repeat visit outpatients, this study designed non-experimental case study was descriptive. Data collected in the form of quantitative data and qualitative. The sampling technique used was purposive sampling. Criteria used for the respondent customers are all Hospital Pharmacy Installation employees and repeat visit outpatients Results: The results showed on Financial perspective suggests that ITOR in 2022 was 12,90 and 2023 was 10,91, GPM in 2022 was 19,69% and 2023 was 19,68%, GROS in 2022 was growth 1,25% and 2023 was growth 1,52%. Internal Business Processes perspective suggests that was availability of drugs according to standards However, the value of dead stock drugs at 4.86% and expired drugs at 1.96% is still above the standard value of more than 1%. The results showed on Customers on five dimensions still obtained negative result an average GAP of -0.54 his shows that the IFRS RSUD Dr Harjono provides unsatisfactory service quality for patients. In the perspective of growth and learning, the ability and motivation to work are in a very high category Conclusion: Financial perspective, internal business processes, growth and learning in the good category and according to standards except for the dead stock and Expired Date values still above the standard. In the customer perspective, they are still dissatisfied with the service, so the pharmaceutical installation requires an improvement strategy
AN ANALYSIS OF DRUG INVENTORY CONTROL EFFICIENCY USING ALWAYS BETTER CONTROL, VITAL ESSENTIAL NON-ESSENTIAL, AND ECONOMIC ORDER QUANTITY METHODS: A CASE STUDY AT ASSALAAM MEDICARE Arief, Khunaisa; Nafisah, Umi; Amalia, Annora Rizky
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.578

Abstract

In-depth control of pharmaceutical inventory is critical, especially in healthcare facility units to ensure the availability of drugs to minimize the risk of stagnation (excess inventory of drugs) and inventory vacancies (shortage or empty level of inventory). The purpose of this study is to determine how inventory level control is carried out at Assalaam Medicare pharmacy using the ABC (Always, Better, Control), VEN (Vital, Essential, Non Essential), and EOQ (Economic Order Quantity) methods for the period January to March 2024. Based on ABC analysis of a total of 572 items of drugs, 151 items of drugs are classified into group A which accounts for 27.970 or 65%, with an investment value of 75% of the total, group B with 215 drug items with a consumption of 10,236 or 24% and an investment of 20%, and group C with 206 items which has a consumption of 4,521 or 11% and an investment of 6%. From the VEN analysis, 26 drug items belong to the vital (V) drug class of group A as an essential service segment. According to EOQ, the highest optimum order quantity is 2.061 items and the lowest optimum value is 17 items for a single order.
Formulation And Physical Quality Test Of Lip Balm Preparations From Yellow Sweet Potato Skin Extract (Ipomoea Batatas L.) Ramadani, Novia Dwi; Safitri, Cikra Ikhda Nur Hamida
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.579

Abstract

Formulation and testing of physical quality of lip balm preparation derived from sweet potato skin extract (Ipomoea batatas L). This study highlights the potential utilization of sweet potato skin, which is often discarded, as a valuable resource due to its high content of natural antioxidants and beneficial compounds. The extraction process was carried out to obtain skin extract, which was then formulated into a lip balm preparation at concentrations of 0.2% and 0.4%. This study was conducted using an experimental research method that aims to determine the activity of yellow sweet potato skin extract (Ipomoea batatas L.). The sampling technique in this study was purposive sampling. The skin used will meet the criteria of being clean, not moldy, not overgrown with fibers, the aroma remains fresh and distinctive, and does not smell bad. The results showed that the lip balm formulation with a concentration of 0.2% showed organoleptic test results, namely cacao aroma, semi-solid form, and brown color. The pH test results were 7 SNI standards, namely 4.5 - 8. The homogeneity test results were homogeneous preparations. The results of the spreadability test showed 4cm with a standard of 3-5 cm. So the conclusion from the concentration of 0.2% and 0.4% which showed good results was 0.2% because it met good physical quality standards.
OVERVIEW OF HPV(human papillomavirus) VACCINE ACCEPTANCE IN STUDENTS Desty, Rani Tiara; Subarti, Dwi
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.580

Abstract

Cervical cancer is the third most common cancer among women worldwide, with more than 75% of cases occurring in developing countries. Cervical cancer is the second most common cancer case in Indonesia. The government is preparing a strategy to prevent cervical cancer with HPV vaccination, one of which is for unmarried teenagers. This is supported by the fact that intercourse is now becoming more free and many people are having sexual relations in the 17 to 21 year age group. Many teenagers are afraid to get the HPV vaccination. Wrong beliefs can influence the acceptance of cervical cancer management and prevention. This study was aims to determine the acceptance of HPV vaccination as an early prevention of cervical cancer in pharmacy students. The type of research that will be carried out is quantitative descriptive research with a cross-sectional approach. The population in this study were all Pharmacy Students Class of 2024. The sample taken in this study was a total sampling with a total of 142 students. The variable studied was student acceptance of HPV vaccination. The instrument used was a questionnaire with Google Form. Data analysis using univariate. The results of research on acceptance of the HPV vaccine among students show that the majority of respondents were female (93.7%). More than half (54.9%) of respondents were 18 years old. More than half, 55.6% of respondents, were less able to receive the HPV vaccine. Education among teenagers, especially students, regarding HPV vaccination needs to be improved, so that they can understand and accept HPV vaccination and as prospective health workers can become role models for changing health behavior Keywords: Students, Receiving, HPV Vaccine.
Analysis of Secondary Metabolite Compounds and Sunscreen Potential of Red Seaweed Extract (Kappaphycus alvarezii) on the North Coast of Jepara Susiloningrum, Dwi; Handayani, Yanulia; Nafi'ah, Lutfiana Nurulin
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.585

Abstract

Red seaweed (Kappaphycus alvarezii) or Eucheuma cottonii is one of seaweed that is widely cultivated by people in Jepara. Several studies stated that the seaweed has a lot of secondary metabolite content, one of them is Phenolic. It is known that these metabolites have potential to be used as sunscreen.The riserch is experimental and purpose of this study was to analyze secondary metabolite compounds and the sunscreen potential of red seaweed (Kappaphycus alvarezii) with solvent variations (70% ethanol, ethyl acetate and N-Hexane) using the Ultrasound Assisted Extraction (UAE) method. The average of total phenol content of 70% ethanol extract was 8.6%; ethyl acetate extract was 3.25% and N-Hexane extract was 5.23%. Sunscreen activity of red seaweed extract (Kappaphycus alvarezii) based on the highest SPF value in 70% ethanol extract with a concentration of 1000 ppm was 7.72 (extra protection). The best erythema transmission percentage (%Te) value in 70% ethanol extract with a concentration of 1000 ppm was 1.457% (extra protection). The best pigmentation transmission percentage (%Tp) value in 70% ethanol extract with a concentration of 1000 ppm is 3.21% (sunblock).
Larvicidal Activity of Ethanol Extracts of Bidara (Ziziphus mauritiana) Leaves and Fruits Against Aedes aegypti Bestari, Rochmadina Suci; Fikri, Muhammad Ihsanul; Aisyah, Riandini; Puspitasari, Metana; Wahyuni, Sri; Porusia, Mitoriana
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.586

Abstract

Dengue fever vector control uses abate chemicals can harm the ecosystem. One of the plants that can be used as a natural larvicide is bidara. Bidara leaves and fruits easily available and contains flavonoids, saponins, alkaloids, and tannins. The compound have an impact on the mortality of Aedes aegypti mosquito larvae. Contains study design, subject, methods, data collection and data analysis. Research on ethanol extract of bidara leaves and bidara fruit with Poly Ethylene Glycol (PEG) was experimental laboratory design with post-test only controlled group design. The technique of extraction is maseration. The larvae of Aedes aegypti instar III-IV are used, 800 in total, divided into 8 groups. At 6, 12, 18, and 24 hours, the number of dead larvae was counted .Normality and homegenity tests obtained the results of data not normally distributed and not homogeneous, so it is necessary to do the Kruskall-Wallis non-parametric test followed by Mann-Whitney post hoc .The result is bidara leaf extract with a concentration of 1.5% + 3% PEG resulted in 100% larval death in the 24th hour, meanwhile bidara fruit extract with concentration of 1.5% + 3% PEG resulted 70% larval death in 24th hour. Ethanol extract of bidara leaves has better effectiveness than bidara fruit extract in its ability as a larvicide, where bidara leaf extract with a concentration of 1.5% + 3% PEG resulted in 100% larval death in the 24th hour.
Analgesic Effectiveness Study Of N-4t-Butylbenzoyl Acetate Compound In Male Balb-C Strain Mice Siddiq, Hadi Barru Hakam Fajar; Rosida, Rosida; Nurmalasari, Dewi Riskha; Afriani, Resa Try; Yanindra, Yuriko Titan
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.591

Abstract

This study aims to understand the activity and effective dose of N-4t-butylbenzoyl Acetate compound as a pain reliever. The analgesic activity test conducted was divided into 5 treatment groups. The analgesic effect test was performed using male mice from the Balb-C strain. In each test, each group consisted of 5 experimental animals. The first group (negative control) was given 1% Na-CMC suspension; the second group (positive control) received 400 mg/kgBW ibuprofen; while the third, fourth, and fifth groups were successively given 200, 400, and 600 mg/kgBW of N-4t-butylbenzoyl Acetate compound, respectively. After the treatment was given to each test animal, an analgesic test was conducted with a 30-minute interval. After that, it was injected with 1% acetic acid and observed for 180 minutes; every 10 minutes, the movement was observed for all treatments. The analysis was carried out by comparing the number of movements (writing reflex). Data analysis was performed statistically using ANOVA (analysis of variance). The number of mouse activities produced by male mice of the Balb-C strain showed that the N-4t-butylbenzoyl acetate compound at a dose of 1.56 mg had the highest activity, % protection, and % analgesic effectiveness compared to the other two doses. Based on statistical analysis, there was no significant difference in all treatments of the N-4t-butylbenzoyl acetate compound when compared to ibuprofen (positive control)
Compliance Analysis of Vaccine Storage and Distribution at the Samarinda Pharmacy Installation in December 2024 Pamungkas, Asih Rahayu; Taufiqurrahman, Muh.; Simanullang, Raymon
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.592

Abstract

Vaccines are very susceptible to damage, so vaccine management requires special handling. Vaccines if handled not according to the provisions can cause damage to the vaccine so that it reduces or eliminates the potential, and can even cause post-immunization adverse events when administered. The objective of this study is to assess the compliance of immunization vaccine storage and distribution at Samarinda Pharmacy Installation with the Good Distribution Practices (GDP) Guidelines of 2020 and Guidelines for Vaccine Management in Healthcare Facilities of 2021 for the period December 2024. This research approach is qualitative research. Qualitative research is presented in descriptive form. Data collection was carried out by observation using a checklist, document observation in 2024 and interviews with the pharmacist in charge. The population in this study were all immunization vaccines stored at the Samarinda Pharmacy Installation. The results obtained will be compared with the guidelines of good distribution practice and the guidelines for vaccine management in health facilities. Based on the results of the study conducted at Samarinda Pharmacy Installation, the compliance of vaccine storage was 67% based on the GDPN Guidelines of 2020 and 94% based on the Guidelines for Vaccine Management in Healthcare Facilities of 2021. The compliance rate of vaccine distribution was 83% based on the GDP Guidelines of 2020 and 100% based on the Guidelines for Vaccine Management in Healthcare Facilities of 2021.
Antidiarrhoeal Potential of Secondary Metabolites in Betel Leaf (Piper betle): A Systematic Review with Radar Chart Analysis and AUC Evaluation. Cendekiawan, Khrisna Agung; Kintoko, Kintoko; Yuliani, Sapto; Anggraeni, Linda Suci; Wardhani, Firdha Aprillia; Poerwahyuningrum, Neny
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.594

Abstract

Diarrhoea is a widespread gastrointestinal disorder commonly caused by microbial infection, inflammation, or impaired intestinal function. While synthetic antidiarrhoeal drugs are available, their use is often limited by adverse effects and antimicrobial resistance, prompting increasing interest in medicinal plants such as Piper betle (betel leaf). This study systematically reviewed the literature to identify secondary metabolite compounds in Piper betle with antidiarrhoeal potential and to evaluate their biological activities using Radar Chart Analysis (RCA) and Area Under Curve (AUC) methods. A systematic search was performed across PubMed, Scopus, Web of Science, and Google Scholar using predefined keywords. Inclusion criteria comprised studies that investigated Piper betle or its secondary metabolites, reported antidiarrhoeal or related bioactivity, and provided quantitative data suitable for comparison. Studies were excluded if they focused solely on synthetic drugs, were not available in full text, or did not report measurable metabolite data. A total of 35 eligible studies were included after screening 176 records. The findings indicate that flavonoids, polyphenols, tannins, saponins, and catechins in Piper betle contribute to antidiarrhoeal effects through mechanisms that modulate intestinal motility, reduce fluid secretion, activate anti-inflammatory pathways, and exhibit antimicrobial activity. RCA and AUC analyses further demonstrated substantial variability in metabolite composition and antioxidant capacity across studies. Overall, Piper betle exhibits promising therapeutic potential as a natural antidiarrhoeal agent, although further mechanistic and clinical research is warranted.
Self-Medication With Antibiotics By The People Of East Mamungaa Village Rikwan, RIKWAN; Kasim, Athia Kurnia; Suryadinata, A. Moh Whisnu; S.A Belike, Desy Safitri; Gunibala, Ciciliya
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.597

Abstract

The unsupervised use of antibiotics continues to be a pressing public health issue because it may contribute to antimicrobial resistance and increase the likelihood of unwanted health effects. A community’s understanding of when and how antibiotics should be used is one factor that can influence self-medication practices. For this reason, research sought for eva;uatng level knowledge related to independent antibiotic use among residents of East Mamungaa Village. A quantitative descriptive observational approach was selected as it enables a clear depiction of knowledge patterns within the population. A total of 172 individuals 18–65 years asked by purposive sampling, and information was obtained using a structured questionnaire assessing knowledge of indications, safety considerations, and appropriate antibiotic use. The results indicate that 60.5% of participants possessed a moderate level of knowledge, 28.5% demonstrated a good level of knowledge, and 11.0% showed limited knowledge. These outcomes reveal that although most respondents have a basic awareness of antibiotics, important gaps remain—especially in recognizing the dangers of using these medications without clinical guidance. Accordingly, continuous community-based education efforts are needed to strengthen proper antibiotic practices and minimize the risks associated with self-medication.

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