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All Journal Bunda Edu-Midwifery Journal (BEMJ) International Journal of Education, Science, Technology, and Engineering (IJESTE) Jurnal Insan Farmasi Indonesia Journal Pharmasci (Journal of Pharmacy and Science) Review of Multidisciplinary Education, Culture and Pedagogy (ROMEO) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Sains Medisina Health Research Journal of Indonesia JPNM : Jurnal Pustaka Nusantara Multidisiplin Jurnal Dunia Ilmu Kesehatan Jurnal Farmasi SYIFA Health Sciences International Journal Science Techno Health Journal Journal of Studies in Academic, Humanities, Research, and Innovation Indonesian Journal of Mathematics and Natural Sciences Jurnal Pelita Raya (JPR)
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Formulasi dan Evaluasi Hidrogel Ekstrak Etanol Daun Gaharu (Aquilaria malacensis Lamk.) dengan Kombinasi Basis Karbopol 940 dan HPMC K4M Yenny Harliantika; Noval
Journal of Pharmacy and Science Vol. 6 No. 1 (2021): Journal of Pharmacy and Science
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v6i1.208

Abstract

Hidrogel merupakan sediaan topikal dengan cara dioleskan pada kulit. Ekstrak daun gaharu terbukti mengandung senyawa flavonoid yang berperan dalam membantu proses penyembuhan luka. Kombinasi karbopol dan HPMC bertujuan untuk menutupi kekurangan karbopol saat digunakan pada konsentrasi tinggi dan memberikan pH asam. Mengetahui pengaruh kombinasi basis karbopol 940 dan HPMC K4M dan hasil stabilitas evaluasi terhadap formulasi hidrogel ekstrak etanol daun gaharu yang optimal. Metode yang digunakan ekperimental dengan rancangan true-eksperimental. Sampel yang digunakan daun gaharu di Kabupaten Tanah Bumbu. Determinasi, preparasi, ekstraksi, pembuatan hidrogel dan evaluasi. Data dianalisis dengan statistik ANOVA dan Kruskal-Wallis. Formulasi hidrogel dengan kombinasi basis karbopol 940 dan HPMC K4M memberikan pengaruh terhadap formulasi hidrogel ekstrak daun gaharu dengan uji stabilitas evaluasi organoleptik, homogenitas, pH, viskositas, daya sebar dan daya lekat. Hasil formulasi yang dapat mempertahankan stabilitas evaluasi selama penyimpanan 28 hari pada suhu ruangan adalah F2. Hasil uji statistik pH, viskositas, daya sebar dan daya lekat <0,05, p-value <0,05 menunjukkan adanya perbedaan yang signifikan pada tiap formula. Adanya pengaruh kombinasi basis karbopol 940 dan HPMC K4M terhadap formulasi hidrogel ekstrak daun gaharu dan formulasi yang baik terdapat pada F2.
Development and Application of Nanoparticle Technology in Herbal Drug Formulation- A Review Hatmayana, Roosma; Nabillah, Syafira; Windy, Yuditha; Noval
International Journal of Education, Science, Technology, and Engineering (IJESTE) Vol 4 No 2: December 2021
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.ijeste-0402.321

Abstract

Formulations of Herbal medicine are continuously being developed to improve health and treatment through natural ingredients obtained from the surrounding environment with scientific evidence. Common problems in herbal medicine are bioavailability, solubility, absorption of active substances and low stability. Recently, it has become a development trend to enter the realm of nanoparticle technology to its application in herbal drug formulations. Nanoparticle technology is a technology of drug particles are made on the nanoscale (10 nm-1000 nm). Many studies have been carried out on the development and application of nanoparticle-based delivery technology containing natural ingredients, from these results nanoparticle-based delivery technology has succeeded in delivering these natural materials through certain mechanisms in increasing the activity and bioavailability of herbal medicinal compounds. Particles at the nanoparticle scale have distinctive physical properties compared to particles at a larger size, especially in increasing the amount and purpose of delivering drug compounds. Another advantage of nanoparticle technology is the potential to be combined with other technologies, thus opening up opportunities to produce more perfect and targeted delivery systems. Examples of nanotechnologies that can be used are polymer nanoparticles, solid lipid particles, magnetic nanoparticles, and others. The manufacture of preparations based on nanoparticle technology is an alternative in the manufacture of herbal medicines and it is hoped that the bioavailability and therapy produced in the body will be better.
Analisis Faktor yang Mempengaruhi Terjadinya Berat Badan Lahir Rendah (BBLR) di RSUD Muara Teweh Kabupaten Barito Utara Mardiyah, Siti; Yunita, Laurensia; Noval; Salmarini, Desilestia Dwi
Health Research Journal of Indonesia Vol 2 No 2 (2023): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v2i2.318

Abstract

Latar Belakang: Bayi di nyatakan BBLR jika mempunyai berat kurang dari 2500 gram ketika lahir, tanpa memperdulikan usia kehamilan 37-42 minggu. Berat badan lahir rendah (BBLR) merupakan salah satu penyumbang terbesar angka kematian bayi (AKB). Tujuan: Penelitian ini bertujuan untuk mengetahui faktor apa yang mempengaruhi terjadinya BBLR di RSUD Muara Teweh Kabupaten Barito Utara Tahun 2022. Metode: Jenis penelitian retrospektif dengan desain penelitian case control,dengan teknik pengambilan sampel yaitu simple random sampling dengan sampel minimal yg di teliti sebanyak 30 orang secara acak yang terbagi menjadi 2 kelompok yaitu 15 sampel kelompok kasus yaitu BBLR dan 15 sampel kelompok kontrol yaitu bayi lahir berat normal. Hasil: Dari 30 ibu bersalin yang umurnya berisiko <20 tahun dan >35 tahun sebanyak 7 orang (23,3%), usia kehamilan yang berisiko <37 minggu sebanyak 8 orang (26,7%),memiliki komplikasi kehamilan yang berisiko sebanyak 12 orang (40%), kehamilan gamelli sebanyak 3 orang (10%). Hasil uji analisis untuk hubungan faktor umur ibu menunjukkan nilai ρ value sebesar 0,006 (< 0,05), usia kehamilan nilai ρ value 0,002 (< 0,05), komplikasi kehamilan nilai ρ value 0,000 (< 0,05),kehamilan gamelli nilai ρ value 0,224 (> 0,05). Kesimpulan: Dari empat variabel penelitian yang dilakukan menunjukkan ada tiga variabel yang berhubungan yaitu umur ibu, usia kehamilan, komplikasi kehamilan dan satu variabel yang tidak berhubungan yaitu kehamilan gamelli dengan kejadian Berat badan lahir rendah (BBLR) di RSUD Muara Teweh Kabupaten Barito Utara Tahun 2022.
Penetapan Parameter Spesifik Daun Beluntas (Pluchea indica L) Asal Kalimantan Selatan Nisa, Karimatun; Hakim, Ali Rakhman; Noval
Jurnal Farmasi SYIFA Vol 1 No 2 (2023): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v1i2.406

Abstract

Daun Beluntas (Pluchea indica L) dapat tumbuh di daerah kering pada tanah yang keras dan berbatu, pada daerah dataran rendah hingga dataran tinggi. Seiring dengan meningkatnya teknologi bahan alam dan kecenderungan masyarakat, maka diperlukan adanya suatu acuan yang memuat persyaratan mutu bahan alam. Hasil uji kadar ektrak larut air mendapatkan hasil 13.387 %. Pada uji kadar ektrak larut etanol mendapatkan hasil 0,454. Pada skrinning fitokimia menjelaskan bahwa tanaman beluntas mengandung tanin, alkaloid, steroid/terpenoid, flavonoid, dan saponin.
Effect of consuming lemongrass (Cymbopogon citratus) on shortening the postpartum period Meidawati, Gusti Sophia; Rahmawati, Dwi; Noval; Mahdiyah, Dede
Health Sciences International Journal Vol. 2 No. 2: August 2024
Publisher : Ananda - Health & Education Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71357/hsij.v2i2.26

Abstract

Background: Complementary care in some midwifery communities has become important to midwifery practice. One of the reasons why complementary midwifery care is currently widely used is the desire to avoid the side effects of drugs. Based on the birth register at Independent Practice of Midwife Darmawati from September to December 2023, the average number of births was 25 patients a month, with postpartum visit data recorded as 89% of postpartum mothers consuming lemongrass decoction (Cymbopogon citratus) during the postpartum period. Lemongrass is a natural resource proven to speed up the healing process. Lemongrass is rich in potassium, which stimulates blood circulation, improves blood flow, and helps increase endurance. Objective: The aim is to determine the effect of consuming lemongrass decoction on shortening the postpartum period. Method: This research method uses a quasi-experimental research design with a treatment group and a control group design. The population of this study was all postpartum mothers recorded in the IPM Darmawati birth register from September 2023 to January 2024. This research used a tool in the form of an observation sheet which was filled out by respondents in the treatment group every time they drank lemongrass decoction according to the manual for making lemongrass decoction and how to consume it. Results: In the intervention group 25% had the postpartum period in the normal category, and 75% in the fast category, while in the control group 100% were in the normal. The Wilcoxon test results show a significant difference between the treatment and control group with a p-value of 0.042. Conclusion: Consuming lemongrass decoction significantly shortened the postpartum period.
ANALYSIS OF GRADUATE COMPETITIVENESS MANAGEMENT AND DEVELOPMENT STRATEGY OF PUBLIC VOCATIONAL HIGH SCHOOLS IN PALU CITY, CENTRAL SULAWESI PROVINCE M, Rudin; Noval
REVIEW OF MULTIDISCIPLINARY EDUCATION, CULTURE AND PEDAGOGY Vol. 1 No. 1 (2021): NOVEMBER
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.759 KB) | DOI: 10.55047/romeo.v1i1.54

Abstract

The purpose of this research is to find out and analyze the Competitiveness of Graduates of Public Vocational High School (SMK) 2 of Palu in Central Sulawesi Province as well as the Development Strategy. This type of research is qualitative research with informants selected as many as three people. Data collection uses observation, interview and documentation techniques. Data analysis techniques used are (1) Data collection (2) Data Reduction (3) Presentation of Data (4) Verification (5) Conclusions. According to the findings of the researchers' investigation and analysis, it was concluded that the competitiveness of graduates of Palu Public Vocational High School (SMK) 2 needs to be improved. This is obvious from the information presented during the study's informant interviews. Then there are graduates who remain jobless. Meanwhile, one could argue that the development strategy is acceptable. The footsteps of Palu's Public Vocational High School (SMK) 2, which sends instructors to the Master of Education level, demonstrate it well. Then, Palu Public Vocational High School (SMK) 2 collaborated or signed MOUs with 110 businesses in Central Sulawesi and other provinces.
Identifikasi Kriteria Kelayakan Medis Terhadap Penggunaan Kontrasepsi Akseptor KB Suntik 3 Bulan Di Puskesmas Sungai Bilu Vriska Nata; Nurul Hidayah; Noval; Dwi Sogi Sri Redjeki
Bunda Edu-Midwifery Journal (BEMJ) Vol. 8 No. 1 (2025): Februari 2025
Publisher : Akademi Kebidanan Bunga Husada Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54100/bemj.v8i1.307

Abstract

Latar Belakang: Berdasarkan hasil yang sudah didapatkan dengan 51 responden kriteria kelayakan medis kategori I sebanyak 34 responden (66,6%) Kondisi tidak ada pembatasan apapun dalam penggunaan metode kontrasepsi, Kategori II sebanyak 3 responden (5,8%) Kondisi dimana penggunaan kontrasepsi lebih besar manfaatnya dibandingkan dengan resiko, Kategori III sebanyak 14 responden (27,8%) Kondisi dimana penggunaan kontrasepsi lebih besar manfaatnya dibandingkan dengan resiko, Kategori IV Kondisi dengan resiko kesehatan yang tidak dapat diterima pada suatu penggunaan metode kontrasepsi. Tujuan: Mengidentifikasikan kriteria kelayakan medis pada pengguna kontrasepsi akseptor KB suntik 3 bulan. Metode: Jenis penelitian ini adalah kuantitatif dengan menggunakan desain penelitian deskriptif. Sampel pada penelitian ini berjumlah 51 responden diambil dengan total sampling. Pengumpulan data menggunakan chekclist dan roda klop KB. Teknik analisis data secara univariat. Hasil: Dari hasil penelitian berdasarkan umur terbanyak yaitu tidak beresiko yaitu 31 responden (60,7%), berdasarkan paritas terbanyak yaitu multipara 33 responden (64,7%), berdasarkan pendidikan terbanyak yaitu SMA 21 responden (41,1%), berdasarkan pekerjaan terbanyak yaitu IRT 44 responden (86,2%), berdasarkan kriteria kelayakan medis terbanyak kategori I yaitu 34 responden (66,6%). Simpulan: Berdasarkan kriteria kelayakan medis kategori I sebanyak 34 responden (66,6%), Kategori II sebanyak 3 responden (5,8%), Kategori III sebanyak 14 responden (27,8%), Kategori IV Kondisi dengan resiko kesehatan yang tidak dapat diterima pada suatu penggunaan metode kontrasepsi.
EKSTRAK DAUN ECENG GONDOK (Eichhornia crassipes) SEBAGAI ALTERNATIF ANTIBAKTERI ALAMI TERHADAP KARIES GIGI Rahimah, Asri; Darsono, Putri Vidiasari; Noval; Nastiti, Kunti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i1.2223

Abstract

Dental caries is a major problem of dental and oral health. One of the bacteria that causes dental caries is Streptococcus mutans. Water hyacinth leaves contain flavonoids, tannins, alkaloids, and terpenoids that can be used as antibacterials. Objective for identifying the antibacterial activity of water hyacinth leaf extract (Eichhornia crassipes) against Streptococcus mutans bacteria. Type of research used True Experimental with a Posttest-only Control Group. Antibacterial activity using well-diffusion method and determination of MIC and MBC using liquid dilution method analyzed non-parametric statistics Kruskal-Wallis and Mann Whitney. Results from this water hyacinth leaves contain secondary metabolites, namely flavonoids, tannins, alkaloids and terpenoids. The antibacterial activity test of water hyacinth leaf extract has an inhibition zone diameter of 15.41 mm. The MIC value at a concentration of 50% and does not have a MBC. Research results show that hyacinth extract is bacteriostatic against Streptococcus mutans bacteria that cause tooth decay.
FORMULASI DAN KARAKTERISASI FITOSOM EKSTRAK TANAMAN BUNDUNG (Actinoscirpus grossus) SEBAGAI ANTIOKSIDAN Febrianti, Dwi Rizki; Noval; Dwi Rizki; Melviani; Mayna; Salwa Nisrina; Akhmad Fadhil Samara
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i1.2410

Abstract

Free radicals are the cause of cell damage and death. Free radical molecules are highly unstable and reactive, and can cause cell damage and metabolic disorders. Antioxidants are compounds that can reduce the negative impact of oxidants, enzymes, and metal-binding proteins. Bundung plant (Actinoscirpus grossus) contains secondary metabolite compounds namely flavonoids, tannins, saponins, phenolics, steroids, and terpenoids. Bundung showed moderate antioxidant activity with an IC50 value of 128 ppm. Flavonoids have high polarity, but are difficult to absorb due to their large size and poor solubility in lipids. Phytosomes can overcome the absorption barriers of natural active ingredients, by converting hydrophilic phytoconstituents into hydrophobic or lipid soluble components thereby increasing bioavailability through increased ability to cross cellular membranes and enter into blood circulation. The purpose of this study was to obtain the formulation and characterization of phytosomes of bundung plant extract as an antioxidant. The method uses maceration until a thick extract is obtained. Then, phytosomes of bundung extract were made by thin layer hydration method using rotary vaccum evaporator. The results showed that phytosomes of bundung extract in formula 4 were the most optimal, having a particle size value of 282.63 nm, a polydispersity index of 0.278 nm, a zeta potential of -5.89 nm, an absorption efficiency of 100%, and the best vesicle morphology was evenly distributed, had relatively the same size between one vesicle and another, and there was no aggregation between vesicles.
Faktor-Faktor yang Mempengaruhi Peran Suami dalam Mengikuti Kegiatan Kelas Ibu Hamil di Wilayah Kerja Puskesmas Giri Mulya Mariana; Susanti Suhartati; Noval; Frani Mariana
Science Techno Health Journal Vol. 2 No. 2 (2024): Science Techno Health Journal
Publisher : Science Techno Health Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang Faktor-faktor yang memengaruhi rendahnya peran suami dalam mengikuti kegiatan kelas ibu hamil dapat bervariasi, diantaranya ketersediaan waktu, pandangan budaya, tingkat pendidikan, dan dukungan sosial. Tujuan: Mengetahui faktor-faktor yang mempengaruhi peran suami dalam mengikuti kegiatan kelas ibu hamil di wilayah kerja Puskesmas Giri Mulya. Metode: Rancangan survey analitik dengan pendekatan cross sectional, dan teknik yang digunakan adalah purposive sampling sebanyak 44 responden. Instrumen yang digunakan adalah kuesioner tentang pengetahuan, sikap, dan dukungan tenaga kesehatan dengan analisis uji chi square. Hasil: Berdasarkan hasil penelitian menunjukkan bahwa mayoritas suami tidak berperan dalam kegiatan kelas ibu sebanyak 28 responden (63,6%), pengetahuan suami kurang sebanyak 20 responden (45,5%), sikap suami kurang sebanyak 29 responden (65,9%), dan mendukungnya tenaga kesehatan dalam kelas ibu hamil sebanyak 27 responden (61,4%). Ada hubungan pengetahuan (p=0,000), sikap (p=0,010), dan dukungan tenaga kesehatan (p=0,000) dengan peran suami dalam mengikuti kegiatan kelas ibu hamil di wilayah kerja Puskesmas Giri Mulya. Simpulan: Suami memiliki peran penting dalam mendukung kesehatan ibu dan bayi selama kehamilan, persalinan, dan nifas. Salah satu cara untuk mendukung peran suami adalah dengan mengikutsertakan mereka dalam kelas ibu hamil. Dukungan dari tenaga kesehatan juga sangat penting untuk meningkatkan partisipasi suami dalam kelas ibu hamil.
Co-Authors Akhmad Fadhil Samara Ali Rakhman Hakim Alifah, Rifdah Nur Anisa Safira Nuzullaika Annisa Permata Sari, Annisa Permata Dede Mahdiyah Dede Mahdiyah, Dede Difa Intannia DWI RAHMAWATI Dwi Rizki Dwi Salmarini, Desilestia Dwi Sogi Sri Redjeki Eka Indriyani MS Emily Yee Erawati, Ria Febrianti, Dwi Rizki Frani Mariana Friscilla, Ika Ginting, Dini Tri Putri Br Hatmayana, Roosma Herlambang, Karen Hidayati Ihsan Taufiq Ika Friscila Khairunnisa Khairunnisa Laurensia Yunita, Laurensia Lisda Handayani, Lisda Mareta Puri Rahastine Mariana Mayna Meidawati, Gusti Sophia Melviani Melviani, Melviani Mia Audina Muhammad Reza Pahlevi Mustika Muthaharah Nabillah, Syafira Najib, Mohamad Khoirun Nastiti, Kunti NGURAH WISNU MURTHI Ninda Ayuk Aktaniensia Nisa, Karimatun Nita Hestiyana Noval Noval Novalia Widya Ningrum, Novalia Widya Novita Dewi Iswandari Nurul Hidayah Oktavia, Regina Putri Vidiasari Darsono, Putri Vidiasari Rahimah, Asri Rika Dwi Ayu Parmitasari Safitri, Bella Saftia Aryzki Salwa Nisrina Sarah, Devi Siti Mardiyah Sri Nurdiati Sri Pitaloka Susanti Suhartati Susmita Indah Lestari Syahrizal Ramadhani Sya’adah, Syifa Noer Vriska Nata Windy, Yuditha Yenny Harliantika