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Jurnal Ilmiah Kesehatan (JIKA)
Published by Sarana Ilmu Indonesia
ISSN : 23379847     EISSN : 26862883     DOI : https://doi.org/10.36590/jika
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Ilmiah Kesehatan (JIKA) aims to provide forum exchanges and interfaces between researchers and related practitioners in the field of health. The journal only accepts articles from original research results (top priorities), case study articles (not priorities), and scientific studies of recent articles (not preferences). JIKA is a scientific journal that contains research papers from the field of health sciences including: Medical and clinical research, food and nutrition research, public health research, obstetrics management research, nursing management research, and pharmacy research.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 268 Documents
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Study on Predisposing Factors of Adolescent Dysmenorrhoea Winarni, Winarni; Ropitasari, Ropitasari
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.918

Abstract

Dysmenorrhea is the most common complaint of menstrual pain during adolescence. Relevant risk factors for this condition include early menarche (<12). At this age, the reproductive organs have not fully developed, and the narrowing of the cervix can lead to pain during menstruation. The duration of menstruation may be influenced by continuous uterine contractions, which interrupt blood flow to the uterus. The length of the menstrual cycle plays a role in this, as a longer cycle leads to the release of more prostaglandins, causing pain. A family history of dysmenorrhea is an unmodifiable risk factor. This study aims to identify the predispositional factors that affect dysmenorrhea. The research design used is an analytical survey with a cross-sectional approach, which is a study aimed at exploring the correlation between causative factors and their effects, conducted simultaneously. The population consists of all students who experience menstrual pain. The sampling method used in this study was simple random sampling. The results show that the majority of subjects experienced dysmenorrhea, with 44 subjects (60,3%). Conclusion, there is a relationship between family history and exercise habits with the occurrence of primary dysmenorrhea, while no relationship was found between menarche age, menstrual duration, and nutritional status with the occurrence of primary dysmenorrhea.
Characterization of Phytocomponents of Mindi Leaf Extract and Chinese Petai Seeds by LC-HRMS and In Silico Activity Against Alpha-glucosidase Maharani, Maharani; Elya, Berna; Forestrania, Roshamur Cahyan
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 2 (2024): Volume 6 Nomor 2 Agustus 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i2.1007

Abstract

Melia azedarach L. and Leucaena leucocephala L. were two plant species that had attracted attention in phytochemical research due to their bioactive potential. However, research on the phytochemical characterization using Liquid Chromatography – High-Resolution Mass Spectrometry (LC-HRMS) of these two plants was still limited. This study was to identify and characterize the phytochemical properties of Mindi leaves (Melia azedarach L.) and Chinese Petai seeds (Leucaena leucocephala L.), as well as to conduct an in silico study. The research method involved reflux extraction using 70% ethanol as the solvent, qualitative phytochemical identification, and characterization using LC-HRMS. The compounds from LC-HRMS from each extract were analyzed for their bioactivity in silico. The results showed that Mindi leaves (M. azedarach L.) and  Petai cina seeds (L. leucochepala L.) contain alkaloids, saponins, phenolics, flavonoids, and tannins. The results of LC-HRMS analysis showed that 10 compounds were identified in each extract, and 3 of them were Prolylleucine, (3beta, 24R, 24'R)-fucosterol epoxide, and 2,3-Dihydro-1-benzofuran-2-carboxylic acid that is a compound found in both extracts. In silico results show that there is 1 compound in mindi leaf extract, namely Methyl isonicotinic, and 3 compounds from petai cina seed extract, namely trans-p-Coumaraldehyde, L-alanine, and 3-Buten-1-amine, which show pretty strong alpha-glucosidase inhibitory activity inhibits the target protein 3A4A. This research can be a reference for developing mini leaf extract and petai cina seeds as anti-diabetic candidates.
Analysis of Supplement Consumption of Pregnant Women with Orofacial Cleft in Children at RSAB Harapan Kita Jakarta Sani, Shofiyyah Najihan; Tanziha, Ikeu; Ekayanti, Ikeu; Hak, Muhammad Syafudin
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.1228

Abstract

Congenital abnormalities remain a leading cause of death in toddlers, with a global death rate of 8.7 per 1000 live births in 2016. Cleft lip, a congenital birth defect, has an incidence rate in Indonesia that increases by an average of 7,500 cases per year. One of the exogenous factors influencing the occurrence of orofacial clefts (OFC) is maternal supplement intake. This study aimed to assess the relationship between maternal supplement consumption and the incidence of OFC in children and identify the dominant factors in maternal supplement intake. The study employed an observational analytic method with a case-control approach, involving 70 maternal samples calculated using the Lemshow formula. Data for the case group were obtained from mothers who underwent treatment at RSAB Harapan Kita Jakarta. The sampling method used was non-probability convenience sampling, and the data were analyzed using univariate, bivariate, and multivariate methods. The results showed a tendency for supplement consumption and maternal zinc requirements to increase the risk of OFC in children. However, a significant relationship was found between the timing of supplement consumption and the adequacy of folic acid, Vitamin B6, and Vitamin B12 supplements. In the multivariate analysis, the dominant risk factors were the need for folic acid and zinc in mothers. Based on the study results, it is recommended that local government regulations consider these factors to optimize the management and prevention of non-syndromic OFC in children, especially in Jakarta.
Evaluating the Hepatoprotective Effects of Barley on Alloxan-Induced Liver Damage in Diabetic Male Wistar Rats Dinata, Erica; Meldawati, Meldawati; Halim, Yeni
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.1232

Abstract

Type 2 diabetes mellitus often leads to non-alcoholic fatty liver disease, affecting 69-74% of patients. Barley (Hordeum vulgare) offers a potential therapeutic alternative with safer interventions. This study aimed to explore the effects of barley on liver histopathology in alloxan-induced male Wistar rats and compare it with metformin. The research was conducted using a laboratory experimental design with 36 male Wistar rats divided into six groups: normal control, negative control (alloxan induction without treatment), positive control (metformin), and three treatment groups with variations in barley administration. Treatment group 1 received barley before and after alloxan induction, treatment group 2 received barley and standard feed after alloxan induction, and treatment group 3 received standard feed mixed with barley after alloxan induction. Barley was administered for 28 days, and histopathological analysis was performed at the end of the study. Data were analyzed using the Kruskal-Wallis and Mann-Whitney tests. The results showed that barley was able to improve liver cell damage, although not as effectively as metformin. The positive control group with metformin showed an average liver damage score of 148,33 with 53,03% normal cells and 15,28% necrotic cells. In contrast, the barley treatment groups showed average liver damage scores of 169,67 and 159,67. Thus, barley can improve liver histopathology in alloxan-induced rats, highlighting its potential as a safe herbal therapy for preventing and managing liver damage caused by oxidative stress in diabetes mellitus.
Gestational Age and Premature Rupture of Membranes with Neonatal Asphyxia Destariyani, Elvi; Widiyanti, Desi; Yuniarti, Yuniarti; Yulyana, Nispi
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.595

Abstract

Neonatal deaths in Southeast Asia are caused by asphyxia and in Indonesia asphyxia is the cause of infant death. The research was conducted with the aim of analyzing the relationship between premature rupture of membranes (PROM) and gestational age with neonatal asphyxia. The research uses a quantitative approach with a case control type of research. The research was carried out at Argamakmur Hospital in December 2022. The research population was mothers who gave birth at Argamakmur Hospital in January - October 2022 with a sample size of 214 subjetc with details in the case group of 107 subject and the control group of 107 subject. Data collection uses a data collection format. The collected data was subjected to univariate and bivariate data analysis. Bivariate analysis uses the Chi-Square test. Based on data analysis, it is known that there is a relationship between premature rupture and neonatal asphyxia and there is a relationship between gestational age and neonatal asphyxia. It is hoped that health workers will provide communication, information and education on factors that cause asphyxia as an early detection effort and provide opportunities for health workers in the Arga Makmur Hospital environment to take part in skills training in managing asphyxia
Serum Vascular Endothelial Growth Factor (Vegf) Levels and Alberta Stroke Program Early CT Score (Aspects) in Ischemic Stroke Patients Fakhri M, Faisal; Bahar, Ashari; Bintang, Andi Kurnia; Walenna, Nirwana Fitriani; Tammasse, Jumraini; Muis, Abdul
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.679

Abstract

Stroke is the second leading cause of death and disability worldwide. Where the most common occurrence of ischemic stroke is 85% of all stroke cases. Vascular Endothelial Growth Factor (VEGF) is a dimeric glycoprotein with angiogenic and neuroprotective effects. Alberta Stroke Program Early CT Score (ASPECTS) can be used to assess the extent of acute ischemic stroke in the middle cerebral artery territory as a simple semiquantitative instrument. Method a cross-sectional study in acute ischemic stroke patients with an onset of 3-14 days. The VEGF assessed was serum VEGF and ASPECTS assessment to determine the extent of the lesion. Total ASPECT score is 10 points (normal), score > 7 (lesion area < 1/3 MCA), score < 7 (lesion area > 1/3 MCA). Of the 37 patients, the majority of patients were women (62,2%) with hypertension being the most common comorbid. All risk factors had no significant relationship to VEGF levels (p-value>0,005). There was a significant difference between the two ASPECTS categories on serum VEGF levels (p-value=0,001), A significant correlation occurred in serum VEGF levels with ASPECTS (p-value=0,000; r-0,600). Conclusion higher VEGF levels increase cerebral infarction.
Effectiveness of Hot Herbal Compress and the Waistband to Reduce Height the Fundus of Uterus Widiyanti, Desi; Destariyani, Elvi; Yuniarti, Yuniarti; Yulyana, Nispi
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.944

Abstract

The disrupted recovery process of postpartum mothers can lead to subinvolution which is one of the causes of postpartum hemorrhage, with the current incidence rate in Indonesia 5% - 20% of deliveries. Treatment in the postpartum period is influenced by cultural factors in the community such as the use of waistband and hot herbal compresses. The purpose of this study was to determine the effectiveness of hot herbal compresses and the use of waistband to reduce the height of the uterine fundus. This research method is quantitative with a Quasi-experimental approach with two group pre-posttest design with a total sample of 60 postpartum mothers and taken by using purposive sampling technique. The results showed that the average decrease in uterine fundal height in the hot herbal compress group and the waistband group had a significant difference with p value <0,05. In conclusion, there was a more significant decrease in the height of the fundus of uterus by giving hot herbal compresses. It is hoped that the use of hot herbal compresses by postpartum mothers as an alternative non-pharmacological therapy.
Comparison of Giving Mecobalamin Supplements to Improve the Severity of Painful Diabetic Neuropathy Irsyadat, Andi Muhammad; Aulina, Susi; Goysal, Yudy; Zainuddin, Andi Alfian; Lotisna, Mimi; Amran, Muhammad Yunus
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.874

Abstract

Diabetic Painful Neuropathy (DPN) is caused by the progressive loss of nerve fibers due to hyperglycemia, oxidative stress, andhomocysteinemia. Mecobalamin supplementation has shown potential in improving peripheral neuropathy symptoms by enhancing nerve conduction and alleviating neuropathic pain. However, its efficacy data remains limited. This research to investigated the effect of mecobalamin supplementation on the severity of Painful Diabetic Neuropathy in type 2 diabetes mellitus patients. This research is a non-randomized clinical trial, 16 patients were given 500 ?g of intramuscular Mecobalamin 8 times over 30 days (n=8) and 5 times over 10 days (n=8). Subjects underwent measurements VAS, TSS, BDNC and ENMG before and after intervention. VAS (p-value=0,022), TSS (p-value=0,020) and BDC (p-value=0,003) was significant improved in 8 times administration group. VAS (p-value=0,045) dan BDC (p-value=0,014) was significant improved in 5 times administration group, where TSS improved but not significant. The 8 times administration group was better compared to the 5 times administration group in improvement of VAS (p-value=0,016). Based on this research, The addition of mecobalamin 8 times and over 5 times in the management of Diabetic Neuropathic Pain can be useful in reducing neuropathic pain.
Psycometric Test of Indonesian version of The Self-rated Fall Risk Questionnaire in Elderly Community Salsabila, Dika Tiara; Komalasari, Dwi Rosella
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.879

Abstract

Falls are common problem and often occur in the elderly due to decreased body abilities, so a valid and consistent Instrumen is needed to see how high the risk of falls is in the elderly with the Self-rated Fall Risk Questionnaire (SRFQ). So, the practical application of this questionnaire is to pay attention to the dangers of environmental conditions regarding falls in the elderly and support the family to avoid the risk of falls in the elderly which can occur due to decreased balance disorders and the need for physiotherapy. Determining the validity and reliability of the Self-rated Fall Risk Questionnaire’s Indonesian version was the goal of this study. This study was in the methodological study that conducted in September 2023 at Elderly Community Gonilan village, Sukoharjo. There were 58 subjects. Participation this study that choosen by purposive sampling. The SRFQ was given 2 times with an interval of 2 weeks. Between the two measurement sessions, the Indonesian version of the SRFQ test-retest reliability results were very good (ICC 0,989, p-value < 0,001, and 95% CI: 0,982-0,994). Good Internal Consistency was a Cronbach’s Alpha value was 0,829. Based on the content validity results shown, the corrected correlation item value was below 0,3. There were 3 items. Concluded was that the Indonesian version of the SRFQ is declared reliable, but the content validity of the 3 items needed to be retested.
Electrocardiogram Analysis-Based to Track Fatigue during Commercial Home Construction Tasks Artanto, Ardi; Ghiffari, Ahmad; Noviyanti, Noviyanti; Utama, Budi; Tia Fhadillah, Rafika; Anisa Suardin, Lucille
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.970

Abstract

The presence of fatigue among workers in the commercial house construction industry presents substantial obstacles to both the personal welfare of individuals and the overall efficiency of construction projects. The objective of this study is to investigate how individual factors, namely nutritional status, affect degrees of fatigue in this specific occupational group. Data was gathered from 45 construction workers in November 2023 using a cross-sectional methodology. Total sampling approaches were employed, and persons with pre-existing health issues were excluded. Analyzed were the univariate and bivariate data, which uncovered a noteworthy correlation between nutritional status and tiredness level (p-value=0,028). Although there were no significant correlations between age and sleep quality, the results emphasize the significance of dietary determinants in influencing tiredness levels among construction workers. Implications arise from the necessity of implementing specific interventions for example wellness and occupational diet program to encourage adequate nutrition and improve the well-being and productivity of workers in the construction sector. These findings enhance the progress of occupational health research and offer potential applicability for guiding standard of procedure and practical methods to prevent fatigue-related hazards especially in construction environments.

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