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JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 468 Documents
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Healthcare services in Palestine, overcoming the challenges and opportunities for improving quality of medical care: A narrative review Al-Ramlawi, Doaa; Nurhaeni, Ismi Dwi Astuti; Nugroho, Rino Ardhian
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art11

Abstract

Palestinians face significant challenges in accessing quality healthcare due to various factors, including a shortage of medical professionals and facilities, inadequate infrastructure and equipment, political unrest, and violence. Despite efforts to reform the healthcare system, many Palestinians continue to struggle to obtain decent healthcare. This study conducted a narrative review using qualitative data collection methods to analyze the difficulties and possibilities for improving healthcare resources and services in Palestine. The research examined the current state of healthcare resources and services in Palestine and identified the primary challenges to expanding access to high-quality healthcare. These results align with the review’s goals by identifying areas that require enhancement to improve healthcare access and quality in Palestine. A narrative review of 18 articles revealed that Palestine's healthcare system requires significant improvements in many areas, such as infrastructure, financing, and governance, to address the existing issues. The formation of primary healthcare clinics increased financing for medical care, and the development of healthcare infrastructure and funding emerged as potential remedies for enhancing the healthcare system in Palestine. Substantial advancement in healthcare infrastructure, financing, and governance are necessary to ensure Palestinians have access to the healthcare services they need to thrive. Our study emphasizes the importance of addressing the challenges faced by the Palestinian healthcare system and highlights potential opportunities for improvement. By implementing the suggested remedies, policymakers and stakeholders can work towards enhancing the quality and accessibility of healthcare services in Palestine.
The changes of serum prostate specific antigen level in advanced prostate cancer patients undergoing palliative transurethral prostate resection Kurniawan, Wikan; Hardi, Hidayu Permata
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art4

Abstract

Background: Total Prostate specific antigen (tPSA) is a substance secreted by the prostate gland. It levels vary depending on the condition of the prostate and typically increase in response to increased prostate volume, cancer, infection, urinary retention and others. Conversely, tPSA levels decrease following a reduction in prostate volume. Palliative transurethral resection of the prostate (pTURP) is a procedure performed to relieve urinary retention in patients with metastatic prostate cancer who are not candidates for, or do not consent to, definitive treatment.Objective: This study aims to compare tPSA levels before and after pTURP in patients with advanced prostate cancer.Method: Using retrospective cross-sectional studyutilized patient medical records and laboratory results to compare pre- and post-operative tPSA levels. Data were collected from the UGM Academic Hospital's medical record between 2019 and 2022. Inclusion criteria included patients with available pre-operativeand post-operative tPSA levels and anatomic pathology results. Tumor characteristics were classified as cT3-4 or cN+ with any PSA level and any ISUP grade. Patients presented with symptoms such as urinary obstruction, pelvic pain, and/or haematuria, and all diagnoses were confirmed via prostate biopsy. Data were analyzed using the Mann-Whitney U test.Results: A total of 40 patients met the inclusion criteria. The mean average age was 72.45 years. The average resection time was 60.42 ± 5.41 minutes, and the mean resected tissue weight was 27.50 ± 8.06 grams. Complications occurred in 30% of patients within 90 days post-pTURP. A significant decrease in tPSA levels was observed after pTURP (p<0.05). Furthermore, the change in tPSA (delta tPSA) showed a linear and positive correlation with the weight of resected tissue.Conclusion: Palliative transurethral resection of the prostate in patients with advanced prostate cancer significantly reduces serum tPSA levels.
Reproductive health education model for university students utilizing social media channels: Designing and testing Wulandari, Respati; Aprianti, Aprianti; Mubarokah, Kismi; Anggraini, Fitria Dewi Puspita
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art5

Abstract

Background: Adolescent growth encompasses physical, biological, psychological, and social aspects, including interest in the opposite sex. Providing information and support related to reproductive health helps adolescents make proper and safe decisions. Objectives: This study aims to design and validate a reproductive health education model for university students.Methods: The study is a mixed method with a multi-stage design using the 4-phase Research and Development design approach (need assessment, model development, implementation, expert validation, and final product). This research involved 221 university students (online survey), 5 managers of adolescent education programs, 6 university students (in-depth interviews), and 10 peer educators (Focus Group Discussion). Data analysis was descriptive and content analysis.Results: The generated reproductive health education model consists of 1)educators (competent, trustworthy, peer, young, survivors, and good-looking), 2)recipients (late adolescents), 3)education methods (two-way, private, repetitive,), 4)education media (social media platforms), 5) educational content (all topics needed by late adolescents), 6)duration (30 seconds/topic), and 7)goals (to increase knowledge, attitudes, and behaviors regarding reproductive health among university students). Expert validity testing: the model was highly accepted and deemed suitable for implementation (94.7%).Conclusion: The educational model developed is encouraged for implementation among university students. Introducing and implementing the model requires support from relevant stakeholders (NGOs, students, faculty, and university stakeholders). Implementation is necessary to prove the model's effectiveness in increasing knowledge, attitudes, and behaviors regarding reproductive health among university students.
Ileocolonic transposition in an HIV patient with an esophageal stricture: A case study Handaya, Adeodatus Yuda; Andrew, Joshua; Susilo, Naufal Caesario Jouhari; Subroto, Polycarpus David; Azriel Farrel Kresna Aditya; Prakosa, Yovan Indra Bayu; Arianda, Daldy; Tyanti, Belvia Adelaida Maiya
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art14

Abstract

Introduction: Esophageal strictures in patients with HIV (Human immunodeficiency virus) are poorly understood in terms of pathogenesis, prevalence, incidence, and surgical management. Case Presentation: This case study is a 50-year-old man who has had trouble swallowing for ten months, which has left him unable to swallow for the past nine months. Clinical examination revealed thoracic esophageal constriction ranging from Vertebra thoracal (VTh) 4-5. Endoscopic findings revealed a convoluted, constricted lumen that impeded scope passage. A contrast-enhanced computed tomography (CT) scan on eight months ago revealed esophageal constriction, with suspicions of tuberculoma and fibrosis in the right upper lung. Reactive HIV results prompted anti-HIV therapy, supported by fine needle aspiration biopsy (FNAB) results, which demonstrated no evidence of malignancy but indicated granulomatous inflammation. Preoperative evaluations, including negative interferon-gamma release assay (IGRA) and sputum Acid-Fast Bacilli (AFB) tests, cleared the way for a three-hour ileocolonic transposition procedure. The procedure involved median and substernal incisions, dissection of the terminal ileum and the right colon as a graft, retrosternal tunnelling, and anastomosis with cervical oesophagus, which resulted in positive outcomes. A week later, the patient reported increased comfort, recovered eating and drinking abilities, and successful surgical incision healing. Conclusion: The ileocolonic transposition appears to be a potential therapeutic option. This safe and effective alternative not only addresses dysphagia but also improves the overall quality of life.
Thyroid hormone as a clinical predictor in acute exacerbation of COPD: Relationship with %FEV1, exacerbation severity, and hospital stay duration Yanuar; Apriningsih, Hendrastutik; Setijadi, Ana Rima; Reviono; Adhiputri, Artrien
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art9

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality worldwide. Acute Exacerbations of COPD (AECOPD) significantly impact patient outcomes and healthcare costs. Thyroid hormone dysregulation has been proposed as a potential systemic effect of AECOPD. However, the relationship between thyroid hormones and AECOPD clinical predictors, such as %FEV1, exacerbation severity, and hospitalization duration, remains unclear.Objective: This study aimed to investigate the relationship between thyroid hormones and key clinical predictors in patients with Acute Exacerbation of COPD (AECOPD), including %FEV1, exacerbation severity, and Length of Stay (LOS).Method: This is a cross-sectional study which included 32 patients admitted for AECOPD from November 2023 to January 2024 at Sebelas Maret University Hospital. Thyroid function was assessed by measuring serum levels of Thyroid-Stimulating Hormone (TSH), Free Triiodothyronine (FT3), and Free Thyroxine (FT4). We evaluated the association between thyroid hormone levels and Forced Expiratory Volume in 1 second (FEV1), severity of exacerbation, and Length of Stay (LOS).Results: The study found a significant positive correlation between FT3 and %FEV1 (r=0.414, p=0.019), indicating a relationship between higher FT3 and better lung function. A significant negative correlation was observed between FT3 and exacerbation severity (r=-0.506, p=0.003), then FT3 and LOS (r=-0.350, p=0.050). FT4 also negatively correlated with exacerbation severity (r=-0.367, p=0.039). The optimal cut-off for FT3 to predict severe exacerbation was <2.65 pmol/L, with a sensitivity of 80.8% and specificity of 100%.Conclusion: The study indicates a significant relationship between thyroid hormones, particularly FT3, and clinical outcomes in AECOPD patients. These findings suggest that thyroid hormone assessment could be useful in predicting the severity of acute COPD exacerbations, contributing to more targeted management strategie.
Vitamin D receptor polymorphism associated with obesity in productive age population: A cross-sectional study Yohana; Meiyanti; Hartanti, Monica Dwi; Margo, Eveline; Zuraida, Reni
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art6

Abstract

Background: Obesity is influenced by genetic factors, lifestyle, and environmental factors. This increase in obesity gives rise to various chronic disease problems.Objectives: This study aimed to identify genetic variations of Vitamin D receptors and determine the relationship to obesity in terms of body mass index and body fat percentage in the working group.Methods: This study is an analytical observational study with a cross-sectional research design approach in the Jembatan Dua area, Angke sub-district, West Jakarta. The research instrument used was a questionnaire to obtain characteristic data, as well as an examination of VDR gene variations rs1544410, rs2228570, rs7975232, and PCR examination to obtain data on gene variation.Results: The results obtained are as follows: the average age of subjects was 42.24, with 58.1% females. A total of 39 (69.1%) are Javanese. Thirty-one (50%) subjects were included in the category of obesity (BMI> 25), and 41 (66.1%) subjects were obese category based on the body fat percentage. The results of bivariate analysis obtained SNP VDR FoxI gene obtained a significant relationship with body mass index with a p-value of 0.047, while the VDR BsmI gene obtained a statistically meaningful relationship with body fat percentage with a p-value of 0.043.Conclusion: FoxI and BsmI VDR polymorphisms are associated with body mass index and body fat percentage.
Early-onset squamous cell carcinoma in xeroderma pigmentosum: A rare case Susanto, Claudia; Paramita, Deryne Anggia
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art16

Abstract

Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis characterised by photosensitivity, dry skin, pigmentary abnormalities, premature skin aging, and skin cancers at an early age. This case report aims to alert health professionals about this disease, considering the rarity of the disease and the need for an early diagnosis of patients with XP. A 4-year-old boy was referred to our department with multiple painful ulcerated masses over his head and face, which had developed over the past two years. At the age of 6 months, the patient started to develop hyperpigmented spots of numerous sizes on his face, and gradually spread to the other sun-exposed areas of his body. He also had dry skin, photophobia, redness, and watery eyes. Dermatological examination showed multiple ulcerated erythematous nodules at the temporal and frontotemporal region; multiple scaly, hyperpigmented macules, papules, and cutaneous horns at the facial region; multiple hypopigmented and hyperpigmented macules, generalised distributed, predominantly over the sun-exposed areas. A biopsy examination from one of the nodules showed keratinising squamous cell carcinoma (SCC). The patient was diagnosed with xeroderma pigmentosum and was treated with multidisciplinary assessment involving dermatology, paediatric, oncology surgery, ophthalmology, and otolaryngology. The diagnosis in this patient is made clinically based on history taking, physical examination, and confirmation of malignancy from biopsy. Early diagnosis of XP is crucial for decreasing the development of neoplasms, which could improve the patient’s quality of life.
Exploring quality of life and psychological distress in conjunctival tumor patients: An Indonesia cross-sectional study Purnomo, Joko; Indrakila, Senyum; Soewoto, Widyanti; Malindha, Erma; Zulfan; Prastawa, Reza Pahlevi; Asmara, Yusuf Vindra
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art10

Abstract

Background: Conjunctival tumor patients tend to exhibit a compromised health-related quality of life (HR-QoL) as a consequence of their condition.Objectives: To explore the quality-of-life (QoL) of conjunctival tumor patients and its association with psychological distress in Indonesia.Methods: A cross-sectional study with simple random sampling was used. Data collection occurred from May 9 to August 31, 2024. The health-related dimensions of quality of life were measured utilizing the reliable RAND SF-36, while psychological distress was assessed with the Hospital Anxiety and Depression Scale (HADS). We performed statistical analyses using version 26 of IBM SPSS, with normality assessed via skewness.Results: A total of 260 conjunctival tumors completed health assessments, revealing significant psychological distress and the RAND SF 36 questionnaire. The mean age was 51, 52.3% male, and 86.2% married. Participants had an average HADS anxiety score of 9.52, with 60.8% exhibiting anxiety, notably higher in those with malignant tumors (mean score: 10.64) compared to benign tumors (mean score: 8.57, p<0.001). Depression scores averaged 6.97, with 37.7% showing potential mild disorders. Health-related quality of life (HR-\QoL) was appraised across various domains, alongside overall physical functioning, averaging 60.76; benign patients scored significantly higher (71.95) than malignant patients (47.50). Correlations indicated that higher psychological distress negatively impacted QoL, with anxiety showing a strong correlation coefficient of -0.433 and depression at -0.306 (both p<0.001).Conclusion: Psychological distress is prevalent in conjunctival tumor patients, adversely affecting their QoL. These findings highlight the necessity of targeted interventions to enhance both physical fitness and mental wellness—challenges in this population. Further research is essential to develop effective support strategies tailored to their needs.
The impact of coblation and non-coblation techniques on hemorrhage and pain outcomes in tonsillectomy: A meta-analysis Kuncahyo, Sandi Dwi; Putra, Mega Memory Rahasa; Istyawati, Ersty
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art13

Abstract

Tonsillectomy, a common surgical procedure, carries significant complications, including haemorrhage and postoperative pain, impacting patient morbidity and mortality. This study explores the effectiveness of coblation compared to traditional non-coblation techniques in managing these complications. Coblation, proposed to reduce risks associated with tissue removal, was evaluated through a systematic literature search using databases such as PubMed, Google Scholar, and Cochrane. The selected studies were rigorously analysed based on specific inclusion and exclusion criteria. Results from ten journals included in this review indicate no significant difference in primary haemorrhage outcomes between coblation and non-coblation techniques (odds ratio 1.49; 95% CI: 0.68-3.23; p=0.32), with low heterogeneity (I²=0%; p=0.81). However, coblation was associated with a statistically significant reduction in secondary haemorrhage (odds ratio 0.66; 95% CI: 0.45-0.95; p=0.03) and postoperative pain (effect size -0.84; 95% CI: -0.94 to -0.74; p < 0.00001). These findings suggest that coblation may be more effective in reducing secondary haemorrhage and postoperative pain compared to non-coblation techniques.
Motivational interviewing-based health coaching to improve diabetes knowledge and manage blood glucose: A quasi-experimental study Jafar, Nuurhidayat; Setyawati, Andina; Malasari, Silvia; Grestin Sandy R
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art8

Abstract

Background: Diabetes management relies significantly on patient knowledge, which affects personal care practices and overall well-being. However, many patients face challenges in managing their condition due to insufficient support and motivation. Objective: This study aimed to evaluate the effectiveness of a motivational interviewing-based health coaching program using the  Focus, Identify, Reflect, Act (FIRA) model in enhancing diabetes knowledge and managing blood glucose, BMI, and blood pressure.Methods: A quasi-experimental study was conducted involving 121 adult participants with type 2 diabetes, allocated into intervention (n = 61) and control (n = 60) groups. The intervention group received six bi-weekly health coaching sessions over three months, based on the FIRA model integrated with motivational interviewing techniques. Pre and post-intervention assessments were conducted to evaluate diabetes knowledge, fasting blood glucose, BMI, and blood pressure. Statistical analysis included paired t-tests for within-group comparisons and independent t-tests or Mann-Whitney U tests for between-group analyses, based on data distribution.Results: The intervention group exhibited a significant improvement in diabetes knowledge (mean change = +3.80; p < 0.0001), while the control group showed a decline (mean change = -2.97; p < 0.0001). A significant reduction in fasting blood glucose was also observed in the intervention group (mean change = -17.00 mg/dL; p = 0.015), in contrast to a non-significant increase in the control group (mean change = +3.00 mg/dL; p = 0.365). No significant changes were found in BMI and systolic blood pressure. Diastolic blood pressure increased significantly in the control group (p = 0.001), while the decrease in the intervention group was not statistically significant (p = 0.432); the between-group difference was also not significant (p = 0.226).Conclusion: Motivational interviewing-based health coaching effectively improves diabetes knowledge and blood glucose management. Further studies are recommended to explore long-term impacts and personalised strategies to optimise patient outcomes.

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