cover
Contact Name
Tongku Nizwan Siregar
Contact Email
jkh@usk.ac.id
Phone
+626517551536
Journal Mail Official
jkh@usk.ac.id
Editorial Address
Jl. Teungku Hasan Krueng Kalee No. 4, Kampus FKH Unsyiah, Kopelma Darussalam, Banda Aceh 23111, Indonesia
Location
Kab. aceh besar,
Aceh
INDONESIA
Jurnal Kedokteran Hewan
ISSN : 1978225X     EISSN : 25025600     DOI : 10.21157
Core Subject : Health, Science,
Jurnal Kedokteran Hewan (J. Kedokt. Hewan), or Indonesian Journal of Veterinary Sciences is a scientific journal field of veterinary sciences published since 2007, published FOUR times a year in March, June, September, and December by Universitas Syiah Kuala (Syiah Kuala University) and Indonesian Veterinary Medical Association (PDHI). Jurnal Kedokteran Hewan is a double-blind review process journal that has been accredited by National Journal Accreditation (ARJUNA), with second grade (Sinta 2), Number: 200 / M / KPTS / 2020. This journal has been registered in the Indonesian Publication Index (IPI), Google Scholar, Sinta, World Cat, Directory of Open Access Journals (DOAJ), EBSCO, Copernicus, Microsoft Academic, and other scientific databases. Jurnal Kedokteran Hewan receives scientific manuscripts in veterinary sciences (veterinary miscellaneous): anatomy, histology, physiology, pharmacology, parasitology, microbiology, epidemiology, veterinary public health, pathology, reproduction, clinic veterinary, aquatic animal disease, animal science, and biotechnology.
Articles 901 Documents
STUDY OF SUPEROXIDE DISMUTASE AND MALONDIALDEHYDE CONCENTRATIONS IN MICE AFTER ADMINISTRATION OF METHANOLIC EXTRACT of Scurrula atropurpurea (BL.) Nour Athiroh; Doti Wahyuningsih
Jurnal Kedokteran Hewan Vol 11, No 1 (2017): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.205 KB) | DOI: 10.21157/j.ked.hewan.v11i1.5431

Abstract

The aim of this research was to investigate the potential effect of methanolic extract of Scurrula atropurpurea (MESA) in reducing oxidative stress through observation of superoxide dismutase (SOD) activity and malondialdehyde (MDA) concentration in mice. In this research, 25 male mice were divided into four groups with five replications. Group I (K1, without MESA) was considered as a control group, while Group II (K2), III (K3), and IV (K4) were given 1000, 2000, and 4000 mg MESA/kg BW, respectively. After 14 days, SOD activity and MDA concentration were measured spectrophotometrically. The SOD activity did not significantly increased (P0.05) in group K1, K2, K3, and K4 with values were 19.469±2.072, 17.4±1.373, 20.53±3.411, and 23.87±2.528 U/ml, respectively. In contrast, MDA concentration was decreased (P0.05) with values of 492.750±19.418, 492.750±19.418, 457.125±30.095, 454.625±19.080, and 475.875±37.659 ng/mL in groups K1, K2, K3, and K4, respectively. It can be concluded that the administration of  MESA tend to increase SOD activity and decrease MDA concentration in this study, thus might be able to reduce  oxidative stress in mice.
PEMBERIAN EKSTRAK EPIDIDIMIS BERPOTENSI MENINGKATKAN KUALITAS SPERMATOZOA KAMBING JANTAN LOKAL Muslim Akmal; Tongku Nizwan Siregar; Sri Wahyuni; Muhammad Hambal; Sugito S; Amiruddin A; Syafruddin S; Roslizawaty R; Zainuddin Z; Mulyadi Adam; Gholib G; Cut Dahlia Iskandar; Rinidar R; Nuzul Asmilia; Hamny H; Joharsyah J; Suriadi S
Jurnal Kedokteran Hewan Vol 9, No 2 (2015): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.3 KB) | DOI: 10.21157/j.ked.hewan.v9i2.2839

Abstract

Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak epididimis (EE) terhadap peningkatan kualitas spermatozoa kambing jantan  lokal. Dalam penelitian ini digunakan 12 ekor kambing jantan lokal, berumur 1,5 tahun dengan bobot badan 10-15 kg dan dibagi atas empat kelompok (K0, KP1, KP2, dan KP3). Kelompok K0, hanya diinjeksi dengan NaCl fisiologis sedangkan kelompok KP1, KP2, dan KP3 diinjeksi EE masing-masing 1, 2, dan 3 ml/ekor selama 13 hari berturut-turut. Pada hari ke-14, dilakukan pengambilan semen kambing dengan elektroejakulator dan selanjutnya dilakukan pemeriksaan kualitas spermatozoa. Hasil penelitian menunjukkan bahwa pemberian EE dengan dosis 1 dan 3 ml/ekor EE selama 13 hari berturut-turut menyebabkan peningkatan kualitas spermatozoa dibanding kelompok kontrol. Berdasarkan hal tersebut dapat disimpulkan bahwa EE berpotensi meningkatkan kualitas spermatozoa pada kambing jantan lokal.
TOPICAL APPLICATION OF Capsicum frutescens LEAF EXTRACT AS HAIR TONIC IN MICE (Mus musculus) Safrida Safrida; Shella Nasmi; Devi Syafrianti
Jurnal Kedokteran Hewan Vol 14, No 4 (2020): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (120.321 KB) | DOI: 10.21157/j.ked.hewan.v14i4.15146

Abstract

The research aims to determine the effect of giving cayenne leaf extract in increasing the length and amount of hair on mice. This research belongs to the type of quantitative research. This research used a Completely Randomized Design (CRD) in consisting of 5 treatment and 4 repetitions. The treatments consisted of NC (negative control, not treated), PC (positive control, given a commercial hair extract), P1 (cayenne leaf extract 10%), P2 (cayenne leaf extract 20%), and P3 (cayenne leaf extract 30%). Research parameters included the increase of the hair length and amount of hairs growing in mice. The result showed that giving extract of cayenne leaf significantly influences the length and amount of hairs in mice, with 10% concentration (P2) was the optimum concentration of the extract that can trigger the hair growth. It can be concluded that given extract of cayenne leaf can increase the hairs growth in mice and has potential as hair tonic.
THE POTENCY OF PULUTAN (Urenalobata L.) LEAVES DECOCTION AS ANTIFERTILITY BASED ON ITS EFFECT ON UTERINE DEVELOPMENT OF BALB C MICE (Musmusculus) Nursasi Handayani; Abdul Gofur
Jurnal Kedokteran Hewan Vol 11, No 4 (2017): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (415.847 KB) | DOI: 10.21157/j.ked.hewan.v11i4.6261

Abstract

The purpose of this research was to determine the effect of decoction of pulutan leaves simplicia(Urenalobata L.) on the development of the uterus of Balb C mice (Musmusculus). Female mice aged 10-12 weeks were given decoction of pulutan leaves simplicia with concentration of 5%, 7.5%, 10%, 12.5%, 15%, and control. The administration of pulutan leaves was performed by gavage for 11 consecutive days. On day 12, mice were dissected, then, the uterus was taken for histological preparations using paraffin method. Data such as uterine diameter and myometrium and epimetrium thickness were analyzed using one way analysis of variance followed by least significant different. The results showed that decoction of pulutan leaves simplicia decrease the uterine diameter and epimetrium and myometrium thickness compared to control. The decrease of uterine diameter and uterine myometrium and epimetrium thickness was started at the concentration of 7.5%. Decoction of pulutan leaves simplicia could reduce uterine diameter and thickness of uterine myometrium and epimetrium, thus, it might decrease the uterine function as the site of implantation. The decline in the function of the uterus might decrease the number of born children, thus decoction of pulutan leaves simplicia is potential as antifertility agent.
PROSPEK SARI BUAH TIN LOKAL (Ficus glumerata Rob) SEBAGAI AGEN PRESERVASI MOTILITAS SPERMATOZOA KAMBING Lalu A. Zaenuri; Trinil Susilawati; Sutiman B. Sumitro; Sri Wahyuningsih
Jurnal Kedokteran Hewan Vol 7, No 1 (2013): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (358.473 KB) | DOI: 10.21157/j.ked.hewan.v7i1.560

Abstract

Penelitian ini bertujuan mengetahui prospek sari buah tin lokal (Ficus glumerata Rob) di dalam pengencer berbasis Tris dan kuning telur untuk mempertahankan motilitas progresif spermatozoa kambing peranakan Boer yang disimpan pada suhu 4-5 C. Perlakuan yang diberikan adalah perbedaan dosis sari buah tin dalam masing-masing pengencer yakni 0, 1, 2, 3, 4, 5, 6, dan 7% (S0, S1, S2, S3, S4, S5, S6, dan S7). Pengamatan motilitas progresif spermatozoa dilakukan segera setelah pengenceran dan setiap 24 jam sampai jam ke-144 setelah pengeceran dan penyimpanan. Persentase motilitas progresifs permatozoa pada kelompok S4 (39,0±2,33) dan S6 (38,0±2,49) lebih tinggi dibandingkan S0; S1; S2; S3; dan S5 yakni masing-masing 32,0±1,86; 30,0±2,11; 29,0±1,80; 31,5±3,66; dan 34,5±3,02. Persentase motilitas terendah ditunjukkan oleh S7 yaitu 22,0±3,59. Dari hasil penelitian ini dapat disimpulkan bahwa sari buah tin mampu mempertahankan motilitas progresif spermatozoa kambing dan konsentrasi optimal dicapai pada 4 dan 6%.
LABORATORY ASSESSMENT OF HYDRATION STATUS OF PRE-RUMINANT ETAWAH GOATS WITH DIARRHEA (Penentuan Status Hidrasi secara Laboratoris pada Anak Kambing Peranakan Etawah yang Mengalami Diare) R Roslizawaty
Jurnal Kedokteran Hewan Vol 4, No 1 (2010): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v4i1.3802

Abstract

Penelitian ini bertujuan mengembangkan panduan yang objektif dan akurat dalam memperhitungkan keadaan hidrasi anak kambing peranakan etawah yang masih menyusui yang mengalami diare. Penelitian inimenggunakan sepuluh ekor anak kambing peranakan etawah yang masih menyusu umur 10-14 hari, jenis kelamin jantan. Dehidrasi diinduksi dengan pemberian preparat diuretika (furosemide 2 mg/kg berat badan secara intramuskulus setiap 4 jam, spironolactone 50 mg per oral setiap 8 jam dan hydrochlorothiazide 50 mg per oral setiap 8 jam) dan larutan katartika (larutan sukrosa 2 mg/kg berat badan dalam 20% larutan aqua, per oral setiap 8 jam) selama 24 jam. Analisis regresi linier digunakan untuk menguji hubungan antara faktor-faktor laboratorisyang dianggap potensial untuk mengevaluasi status hidrasi (packed cell volume, hemoglobin dan total protein plasma dan dehidrasi). Penentuan derajat dehidrasi ditentukan berdasarkan persentase penurunan berat badan. Hasil penelitian menunjukkan bahwa total protein plasma (R2=0,95) berhubungan erat dengan status hidrasi dandapat digunakan sebagai prediktor untuk mengevaluasi status hidrasi pada anak kambing yang masih menyusu.Kata kunci: dehidrasi, anak kambing, derajat dehidrasi
KORELASI FOLIKEL DOMINAN AKIBAT PENYUNTIKAN HORMON PREGNANT MARE SERUM GONADOTROPIN (PMSG) DENGAN PENINGKATAN RESPONS BERAHI PADA KAMBING KACANG Andriyanto A; Amrozi A; Min Rahminiwati; Arief Boediono; Wasmen Manalu
Jurnal Kedokteran Hewan Vol 9, No 1 (2015): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (370.65 KB) | DOI: 10.21157/j.ked.hewan.v9i1.2779

Abstract

Penelitian ini bertujuan mengetahui pengaruh penyuntikan pregnant mare serum gonadotropin (PMSG) terhadap peningkatan respons berahi kambing kacang. Sebanyak 20 ekor kambing kacang betina dewasa kelamin dibagi secara acak ke dalam 5 perlakuan dosis penyuntikan PMSG, yaitu 0,0 (K1); 1,0 (K2); 7,5 (K3); 15,0 (K4); dan 20,0 (K5) IU/kg bobot badan dan diulang 4 kali. Hasil penelitian menunjukkan bahwa pada K3, K4, dan K5 terjadi peningkatan jumlah folikel dominan, total diameter folikel dominan, total volume folikel dominan, dan konsentrasi estrogen dalam serum darah (P0,05), serta menunjukkan gejala berahi yang lebih jelas dibandingkan K1. Konsentrasi estrogen dalam serum darah memiliki korelasi positif dengan jumlah folikel dominan, total diameter folikel dominan, total volume folikel dominan, onset berahi, durasi berahi, perubahan vulva menjadi merah, kebengkakan vulva, peningkatan respons betina terhadap pejantan, dan pergerakan ekor pada saat berahiatau fleging berturut-turut sebesar 53,10; 82,60; 48,80; 53,0; 45,50; 39.40; 32,60; 32,60; dan 80,20% dengan pola kuadratik. Dari hasil penelitian disimpulkan bahwa penyuntikan PMSG pada dosis 7,5; 15,0; dan 20,0 IU/kg bobot badan mampu meningkatkan konsentrasi estrogen dan respons berahi kambing kacang.
THE EFFECTS OF AGE ON BIOCHEMISTRY PROFILES OF ACEH CATTLE BLOOD Lia Khairita; Anita Esfandiari; Sus Derthi Widhyari; Wiwin Winarsih
Jurnal Kedokteran Hewan Vol 15, No 3 (2021): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (374.524 KB) | DOI: 10.21157/j.ked.hewan.v15i3.21698

Abstract

The purpose of this study was to analyze the effects of age on the biochemistry profiles of aceh cattle, which  included examinations of: total protein (TP), albumin, globulin, albumin/globulin ratio (A/G), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP), creatine kinase (CK), blood urea nitrogen (BUN), calcium (Ca), phosphorus (P) and magnesium (Mg) . Sixteen clinically healthy aceh cattle aged 2-4 years old, and 16 aceh cattle aged 4-6 years old were purposively selected for the study. Blood samples were drawn from the jugular vein and subjected to blood biochemistry measurements using commercial kits. The results showed that serum concentrations of TP, globulin, AST and Ca of aceh cattle were significantly (P0.05) higher in age group 4-6 years old, while ALP activity was significantly (P0.05) higher in age group 2-4 years old. In conclusion, age must be considered as a factor when interpreting the blood biochemistry profiles of aceh cattle.
EFFECTIVENESS OF THE FERMENTATIVE EXTRACT OF Lactobacillus acidophilus AS ANTIMICROBIALS AGAINST Aeromonas hydrophila Mst Nahid Akter; Roshada Hashim; Amalia Sutriana; Siti Azizah Mohd Nor
Jurnal Kedokteran Hewan Vol 12, No 4 (2018): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (880.865 KB) | DOI: 10.21157/j.ked.hewan.v12i4.11920

Abstract

The purpose of this study was to evaluate the in vitro and in vivo antimicrobial activity of the commercial Lactobacillus acidophilus (L. acidophilus) cells and cell free extract against Aeromonas hydrophila (A. hydrophila). The in vitro method was carried out using well diffusion method. For in vivo evaluation, the effect of L. acidophilus on the survival rate of Pangasianodon hypophthalmus (P. hypophthalmus) infected with A. hydrophila was evaluated. The well diffusion method showed a significant inhibition ability of L. acidophilus cells against A. hydrophila compared to the cell free extract. The inhibition diameters obtained with cells and cell free extract were 17.23 mm and 15.17 mm, respectively. P. hypophthalmus injected with L. acidophilus cells and cell free extract following challenged with A. hydrophila cells showed survival rate of 70% and 60% respectively, at 2-week post challenged. The gas chromatography-mass spectrophotometry (GC-MS) result revealed that a diverse of compounds was detected in both the L. acidophilus cells and cell free extract, among them the most abundant component was pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl), which showed a promising anticancerous activity and might be played a significant role in the recovery of the infectious P. hypophthalmus. The current study revealed that both cells and cell free extract of L. acidophilus have antimicrobial activity against A. hydrophila.
PROBIOTIK LOKAL MENINGKATKAN KANDUNGAN IgA USUS HALUS TIKUS YANG DIINFEKSI ENTEROPATHOGENIC E.Coli (EPEC): STUDI IMUNOHISTOKIMIA Tutik Wresdiyati; Yeni Setiorini; Sri Rahmatul Laila; Irma Isnafia Arief; Made Astawan
Jurnal Kedokteran Hewan Vol 7, No 2 (2013): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.986 KB) | DOI: 10.21157/j.ked.hewan.v7i2.921

Abstract

Penelitian  ini  bertujuan  menganalisis  pengaruh  pemberian  probiotik  lokal  Lactobacillus  fermentum  (L.  fermentum)  dan  Lactobacillus plantarum  (L.  plantarum)  terhadap profil kandungan IgA usus halus tikus yang diinfeksi   enteropatogenik  E. coli  (EPEC)  menggunakan teknik imunohistokimia.  Sebanyak  90  ekor  tikus  jantan  galur  Sprague  Dawley  digunakan  dan  dibagi  menjadi  enam  kelompok  perlakuan,  yaknikelompok kontrol negatif (A), kelompok perlakuan  L. plantarum  (B), kelompok perlakuan  L. fermentum  (C), kelompok perlakuan  L. plantarumdan EPEC (D), kelompok perlakuan  L.  fermentum  dan EPEC (E),  dan  kelompok perlakuan EPEC (F). Perlakuan dilaksanakan selama 21 hari. Deteksi IgA dilakukan dengan teknik imunohistokimia pada jaringan usus halus. Hasil penelitian menunjukkan bahwa perlakuan probiotik lokalL. fermentum selama 2-3 minggu, dan perlakuan L. plantarum selama 2 minggu mampu meningkatkan kandungan IgA di usus halus tikus. Pada tikus yang dipapar EPEC, L. fermentum lebih baik dalam meningkatkan kandungan IgA dibandingkan L. plantarum.

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