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INDONESIA
Jurnal Farmasi Indonesia
Published by Ikatan Apoteker Indonesia
ISSN : 14121107     EISSN : 2355696X     DOI : https://doi.org/10.35617/jfionline
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmasi Indonesia adalah jurnal nasional (peer-reviewed) yang diterbitkan oleh Ikatan Apoteker Indonesia dua kali dalam setahun sebagai sarana diseminasi ilmu pengetahuan di bidang farmasi, yaitu: farmasi klinis, farmasi masyarakat/komunitas, kimia farmasi, biologi farmasi/famakognosi, farmakologi, pengembangan obat/kimia medisinal, formulasi dan bidang terkait. Artikel yang dipublikasi berupa hasil penelitian dan mini-review. JFIOnline telah mulai diterbitkan sejak tahun 2009 dalam edisi cetak. Pada tahun 2014 mulai dibuat edisi online. Akses artikel pada jurnal tidak berbayar, tetapi dikenakan biaya proses publikasi untuk penulis (open access journal). Mulai bulan Juli 2019 jurnal ini dapat diakses di alamat yang baru yaitu www.jfi-online.org dari alamat sebelumnya www.jfionline.org.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 177 Documents
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Analisis Komparatif Sosiodemografi Terhadap Kepatuhan Penggunaan Antihipertensi Pada Pasien Hipertensi RSUD Puri Husada Tembilahan Husnawati, Husnawati; Pratiwi, Erniza; Syafitri, Yellia; Laia, Cindy Oktaviana; Zulfitri, Reni
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.240

Abstract

Hypertension is a condition where systolic blood pressure increases to more than 140 mmHg and diastolic blood pressure to more than 90 mmHg. Compliance with antihypertensive medication is crucial. Hypertension cannot be cured and must be consistently monitored to prevent complications that can lead to death. One of the factors that can affect the level of medication adherence in patients is the patient's sociodemographics including age, gender, educational level and employment status. The purpose of this study was to analyze the effect of sociodemography on compliance with antihypertensive use in hypertensive patients at Puri Husada Tembilahan Hospital. This research is an observational study with a cross-sectional research design with analytic descriptive method. The sample in this study were patients with a primary diagnosis of hypertension with or without comorbidities who went to the Puri Husada Tembilahan Hospital at the time of the study and met the inclusion criteria. Based on the results of the study it was found that of the 4 sociodemographic aspects studied, namely age, gender, education level and employment status, only education level affected the level of adherence to taking medication in hypertensive patients (P value = 0.000), where respondents with higher education levels had higher levels of higher adherence than respondents with low levels of education.
Analisis Cost of Illness Pasien Covid-19 di Rumah Sakit Jiwa Dr. Soeharto Heerdjan Jakarta Barat Arrang, Sherly Tandi; Fira Rosa, Irene; Notario, Dion
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.265

Abstract

COVID-19 (Coronavirus Disease 2019) is a new case that was reported to have occurred in 2019 in China (Wuhan) and the first case in Indonesia in March 2020. The high increase in cases requiring treatment related to patient care causes an economic burden. Therefore, it is necessary to analyze the economic burden. The analysis uses the Cost of Illness (COI) method. This retrospective research was conducted based on data at RSJ Dr. Suharto Heerdjan for the period December 2020 - July 2021 by calculating the direct medical costs of patients. The analytical method used is Multiple Linear Regression ANOVA using the RStudio application. The number of respondents was 138 patients. In the results of the analysis, it was found that the average total direct medical costs of COVID-19 inpatients based on age was Rp. 6,580,657 (0-5 years), Rp. 8,317,592 (6-18 years), Rp. 8,595,254 (19-30 years old), Rp. 11,787,268 (31-45 years), Rp. 12,537,695 (46-59 years old), and Rp. 16,250,460 (>60 years). Based on gender Rp. 12,416,202 (women) and Rp. 11,285,017 (male). Based on the length of stay, Rp. 7,881,911 (<7 days), Rp. 12,721,150 (7-14 days), and Rp. 26,282,724 (>14 days). Based on the level of severity, Rp. 10,096,730 (mild), Rp. 10,633,881 (medium), and Rp. 16,597,570 (severe). Based on comorbid disease, Rp. 16,981,774 (without comorbid), Rp. 19,670,640 (1 comorbid), Rp. 22,990,759 (2 comorbid), and Rp. 30,231,603 (>2 comorbid). There was a significant effect between length of stay, severity, and comorbid disease on direct medical costs (P<0.05), while there was no significant effect between age and gender on direct medical costs for inpatient care (P>0.05).
Kepuasan Pasien Covid-19 terhadap Layanan Konseling Obat Jarak Jauh oleh Apoteker: Sebuah Studi Lintas Sektoral Cokro, Fonny; Ferlia, Yenni; Usman, Hadiyanto
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.283

Abstract

Telemedicine has been used extensively since the COVID-19 pandemic. However, the non-face-to-face interactions make telemedicine services more challenging. This study was conducted to determine the satisfaction of drug counseling services provided by pharmacists through telemedicine in Jakarta, Indonesia, and to assess the correlation between the type of telemedicine and the provision of pharmacists’ drug counseling. This investigation is cross-sectional, and data were collected from February to May 2022 through Cluster and Snowball sampling methods. Chi-Square was used to measure the relationship between telemedicine models and the provision of drug counseling. Of the 448 respondents, 85.71% received counseling, giving the pharmacist's counseling performance a good value of 64.06-98.18%. More than 80% of respondents were satisfied in all aspects of satisfaction. The bivariate analysis shows a significant relationship between the type of telemedicine and drug counseling services (p=0.032). This research highlights the importance of optimizing telemedicine approaches to enhance patient care in pharmaceutical services.
Gambaran Pola Penggunaan Antipsikotik Pada Pasien Skizofrenia Di Ruang Rawat Inap Rumah Sakit Jiwa Provinsi Jawa Barat Sutrisno, Entris; Mulyani, Yani; Sodik, Jajang Japar
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.344

Abstract

Indonesia experiences an alarming increase in mental disorder cases annually. In 2019, the World Health Organization reported that over 20 million individuals worldwide suffer from schizophrenia. Antipsychotic medications are the preferred treatment option for schizophrenia, as they help alleviate psychotic symptoms and reduce the likelihood of developing the disorder. This study aimed to describe the use of antipsychotic drugs in patients with schizophrenia in the inpatient ward of the Mental Hospital of West Java Province. The study employed a non-experimental, descriptive design with retrospective data collection. Secondary data were used for analysis. The research focused on 194 medical records of patients who received antipsychotic treatment between January and December 2020. The study revealed that 56.19% of prescribed antipsychotic drugs were combination medications, while 43.81% were single drugs. The most common combination of antipsychotic drugs was haloperidol-clozapine, accounting for 36.60% of the prescriptions, and risperidone, a single drug, comprised 19.67% of the prescriptions.
Aktivitas Antioksidan Krim Hidrofilik Ekstrak Metanol Bunga Cempaka Putih (Magnolia alba) Mendra, Ni Nyoman Yudianti; Pratiwi, Dewa Ayu Yunika; Juliadi, Debby
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.385

Abstract

The white champaca flower (Magnolia alba) holds cultural significance for the Balinese society, being employed in religious ceremonies, adorning bridal setting, and enriching the aroma of incense. Moreover, white champaca flowers contain alkaloids, steroids, terpenoids, flavonoids, and phenols that have antioxidant activity. Therefore, it is interesting to determine the antioxidant activity of methanol extract of white champaca flowers and formulated it into an oil in water cream in this study. The extract was formulated into three cream formulas, FI, FII, and FIII with concentrations of 4, 8, and 12%, respectively.  Antioxidant activity was assessed using DPPH (2,2-Diphenyl-1-Picrylhydrazyl) assay with UV-Vis spectrophotometer at a wavelength of 516 nm. The antioxidant activity based on IC50 values for FI, FII, and FIII were 29.72, 25.50, and 25.05 µg/ml, respectively, with IC50 value of vitamin C was 2.93 µg/ml as a standard comparison. The research findings indicate that the methanol extract of white champaca flower o/w cream exhibit a very strong antioxidant activity in vitro. Further research is imperative to investigate the ability of the formulations to delaying the photoaging mechanism through in vivo studies.
Aktivitas Antioksidan dan Profil Fitokimia Ekstrak Metanol Daun Bauhinia purpurea L. dari Pekanbaru Fadhli, Haiyul; Putri, Hefriza
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.478

Abstract

Antioxidants are important bioactive compounds that play a key role in neutralizing free radicals and preventing oxidative damage to cells. Bauhinia purpurea L., locally known as butterfly tree leaves, has been reported to contain various phenolic and flavonoid compounds with promising antioxidant potential. This study aimed to evaluate the phytochemical content and antioxidant activity of methanolic extract of Bauhinia purpurea L. leaves collected from Pekanbaru. Phytochemical screening revealed the presence of flavonoids, phenolics, terpenoids, steroids, and alkaloids. The total phenolic and flavonoid contents were 50.79 ± 1.82 mg GAE/g and 59.10 ± 13.03 mg QE/g extract, respectively. Antioxidant activity measured by the DPPH method showed an IC₅₀ value of 67.58 µg/mL, indicating moderate antioxidant potential. These results suggest that Bauhinia purpurea leaves from Pekanbaru have potential as a natural antioxidant source for herbal and pharmaceutical product development. Geographic factors and extraction methods play a significant role in determining the bioactive content and antioxidant activity of the extract.
Aktivitas Antioksidan Ekstrak Etanol Daun Kale Hijau dan Ungu (Brassica oleracea L.) Nurfarida, Umiyuliatul; Rohmah, Martina Kurnia; Ambari, Yani
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.480

Abstract

Kale (Brassica oleracea L.) is a plant from the Brassicaceae family that is often consumed by the public. Kale leaves contain vitamin C, phenolic compounds, and pigments that have the potential as antioxidants. Kale leaves that are often consumed by the public are green kale and purple kale. This study aims to determine the comparison of antioxidants between green kale and purple kale using the DPPH method. Green and purple kale leaf Simplicial powder was macerated using 96% ethanol solvent. The extraction results were then tested qualitatively for their phytochemical content using phytochemical screening. Antioxidant activity was tested qualitatively and quantitatively (DPPH method). The results showed that the antioxidant activity (IC50) of Vitamin C, purple kale, and green kale leaves extract successively are 3.19 µg/ml (very strong), 100.03 µg/ml (strong), and 144,35 µg/ml (moderate). The antioxidant activity of purple kale leaves is stronger than green kale. leaves.
17-2 EVALUASI PENGELOLAAN OBAT DAN PERBAIKAN BERDASARKAN DIAGRAM FISHBONE DI DINAS KESEHATAN KOTA X TAHUN 2024 Yunartika Puspitasari; Jason Merari Peranginangin; Tri Wijayanti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 17 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.861

Abstract

Effective and efficient drug management is a crucial component in supporting quality healthcare services, particularly at the local government level. This study aims to evaluate the performance of drug management at the Pharmacy Installation of the X City Health Office based on standard indicators, identify non-compliant indicators, and prioritize problems using the Hanlon method. This study uses a descriptive evaluative approach with data collection methods through a retrospective study of drug management documents from 2024, documentation and observation of data from 2025, and in-depth interviews with relevant parties. Data were analyzed based on national drug management indicator standards and content analysis. The priority scale of problems was determined using the Hanlon method. The evaluation results showed that of the 30 indicators analyzed, 60% did not meet standards. The highest priority problem was the non-compliance of drug items with the National Formulary (FORNAS), which had a systemic impact on other indicators. The main causes of the problem include limited human resources (HR) and training on FORNAS, the absence of standardized FORNAS selection and validation at the city level, mismatch between budget allocation and needs, a suboptimal information system, pressure from prescribers to procure non-FORNAS drugs, and the absence of a regular monitoring and evaluation system. The follow-up actions formulated include proposals for additional HR, technical training, improved cross-sector coordination, development of existing application systems, budget optimization, and implementation of regular monitoring and evaluation.
Kaitan Sosio-demografi dan Luaran Klinis pada Pasien Diabetes Melitus TIpe 2 (DMT2) di Rumah Sakit X di Pekanbaru Reza Laila Najmi; Novtafia Endri; Ahmad Muhaimin Rosyadi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 17 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.871

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic disease with a high global prevalence and is one of the leading causes of morbidity and mortality worldwide. Several sociodemographic factors, including age, sex, disease duration, educational level, and comorbidities, are believed to influence clinical outcomes in diabetic patients. This study aimed to analyze the association between sociodemographic characteristics and clinical outcomes among patients with T2DM. A cross-sectional study was conducted at Hospital X in Pekanbaru. The inclusion criteria were patients aged ≥18 years diagnosed with T2DM, receiving oral antidiabetic therapy for at least six months, and having complete medical records. Sociodemographic data were analyzed descriptively, and clinical outcomes were assessed based on HbA1c levels, categorized as “achieved” if HbA1c <7% and “not achieved” if ≥7%. The Chi-square test was used for statistical analysis. Of 95 patients, the majority were aged ≥45 years (84.2%), female (69.5%), and had a disease duration of ≥6 years (83.2%). Target HbA1c was more frequently achieved among female patients (60.6%), those aged ≥45 years (60%), with disease duration <6 years (75%), general educational level (60.2%), and without comorbidities (59.7%). However, no significant association was found between sociodemographic characteristics and achievement of HbA1c targets (p>0.05). Although certain sociodemographic groups tended to achieve better clinical outcomes, the study found no significant relationship between sociodemographic factors and clinical outcomes in T2DM patients. Further research considering lifestyle factors and pharmacological therapy is recommended.
17-2 Variasi Penggunaan Beeswax Lip Balm Stik dari Ekstrak Kulit Nanas (Ananas comosus (L.) Merr.) Hilaliyati, Najmi; Resi Rizki Banjarani; Muhammad Arif; Nursyafni; Widiya Ismail
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 17 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.872

Abstract

Lip balm is a preparation applied to the lips to prevent dryness and chapping. Choosing the right lip balm base will significantly impact its quality and public acceptability. Beeswax has good binding properties, which help to produce a homogeneous mass. In this study, the active ingredient used was pineapple peel because it contains bromelain, which moisturizes the lips. The objectives of this study were to determine the appropriate formulation for lip balm preparations with pineapple peel extract (Ananas comosus (L.) Merr.) as the active ingredient and to determine the effect of varying beeswax base concentrations on the physical stability of lip balm preparations. The method used in this study was an experimental method to see which formulation was suitable. The study obtained a good formula with physical characteristics in accordance with SNI 16-4769-1998, including stability observation, pH measurement, homogeneity testing, irritation testing, moisture testing, and cycling test. The appropriate formula was found in formula 1 with a beeswax concentration of 1%, which produced a good color texture, aroma, adhesive power, and spreadability, a pH level suitable for the lips, no irritation, homogeneity, and stability during storage, resulting in a semi-solid and very smooth lip balm texture when used

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