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Hamsu Kadriyan
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Lombok Medical Journal
Published by Universitas Mataram
ISSN : -     EISSN : 28277686     DOI : -
Core Subject : Health, Science, Engineering,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Mechanical Engineering Public Health
Lombok Medical Journal (LMJ) is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, community or public health research, and medical education to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Focus and Scope of Lombok Medical Journal (LMJ): Basic Science, Clinical Research, Community or public health research, Medical Education
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 98 Documents
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A Review of Borderline Personality Disorder in Adolescence Irawan, Muhammad Renaldi
Lombok Medical Journal Vol. 2 No. 2 (2023): Lombok Medical Journal Volume 2 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i1.2507

Abstract

Personality instability in adolescence that develops into BPD, can make adolescents experience long-term impairment conditions that can reduce the quality of social life, education and work in the future. Borderline Personality Disorder (BPD) is a condition where a person experiences a personality disorder characterized by emotional or mood instability, behavior, self-image and impulsive behavior that is difficult to control by showing symptoms of at least 5 of the 9 diagnostic criteria. It is said to be borderline or threshold because people with this disorder do not meet the characteristics of either neurosis or psychosis, so it is considered to be in between the two conditions. The cause of BPD is unclear, but it is thought to be the result of genetic, psychosocial and neurobiological factors that influence brain development. Therapeutic modalities that can be given to people with BPD include Dialectical Behavioral Therapy (DBT), Mentalization-Based Treatment (MBT), Transference-Focused Psychotherapy (TFP), and Schema-Focused Therapy (SFT).
Sebuah Tinjauan Pustaka Rhinosinusitis Kronis dengan Komorbiditas Atopi Smith, Sima; Hamsu Kadriyan
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2519

Abstract

Latar Belakang: Rhinosinusitis merupakan suatu kondisi terjadinya inflamasi atau peradangan pada mukosa hidung dan sinus paranasal. Rhinosinusitis memerlukan perhatian khusus terutama ketika pasien mengalami kekambuhan bahkan setelah operasi. Kekambuhan rhinosinusitis salah satunya dipengaruhi oleh atopi sebagai komorbiditas rinosinusitis infektif (baik kronis maupun akut). Namun, pada pasien rhinosinusitis kronis (RSK), penanda atopi lebih sering ditemukan. Atopi adalah sindrom klinis yang melibatkan tipe 1 hipersensitivitas (aergi). Melalui proses sistemik, atopi dapat menjadi komorbiditas potensial bagi pasien RSK. Kesimpulan: Gejala yang berkembang pada pasien RSK dengan atopi secara signifikan lebih buruk dan berhubungan dengan timbulnya gejala penyakit. Oleh karena itu, sangat penting untuk mengevaluasi komorbiditas atopi pada pasien RSK untuk mengurangi eksaserbasi dan kekambuhan untuk keberhasilan pengobatan. Kata Kunci: Rhinosinusitis kronis, Atopi, Alergi, Komorbiditas
Heart-type Fatty Acid-binding Protein (H-FABP) sebagai Diagnostik Awal dan Prognostik Infark Miokard Akut Ni Made Utami Wulandari; Putu Wika Pramesti Iswari; Yusra Pintaningrum
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2622

Abstract

Acute myocardial infarction (AMI) remains one of the leading causes of mortality and morbidity worldwide. Early diagnosis and accurate prognosis are vital to improve patient outcomes. Heart-type Fatty Acid-binding Protein (H-FABP) has emerged as a potential biomarker for AMI. H-FABP is a cytoplasmic protein encoded by the FABP3 gene, situated on chromosome 1 in the human genome. It plays a crucial role in active fatty acid metabolism and is implicated in the absorption, cellular metabolism, and/or transport of polyunsaturated fatty acids (PUFAs). During the pathogenesis of acute coronary syndrome (ACS), H-FABP is rapidly released into the circulation when myocardial ischemic injury occurs. Its early detection, around 1-2 hours after AMI, with a peak at 5-10 hours, and normalization within 24-36 hours, makes H-FABP an ideal candidate for early diagnostic and prognostic evaluation in AMI patients. Despite its excellent prognostic value, H-FABP's diagnostic sensitivity outweighs its specificity for AMI. This review discusses the potential of H-FABP as an early diagnostic and prognostic marker for AMI and emphasizes further studies and research are needed regarding the use of H-FABP as a diagnostic and/or prognostic marker for AMI.
Graves Disease: Diagnosis dan Tatalaksana Lestary, Ayundha Rizky; Fatikha Rudia Ahda; I Gede Aditya Satrya Bhuwana Cakra; Ni Made Sri Padma Puspita; Eva Triani
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2754

Abstract

Abstract: Hyperthyroidism is an increase in the amount of thyroid hormone synthesis and secretion by the thyroid gland. Graves Disease (GD) is the most common cause of hyperthyroidism. Graves Disease (GD) is more common in women than men and in patients with a family history of GD. Graves Disease can also be triggered by environmental factors such as stress, smoking, infection, and exposure to iodine. Graves Disease manifests in the form of the Merseburger triad consisting of thyrotoxicosis, diffuse goiter, and ophthalmopathy (orbitopathy) with symptoms of agitation, palpitations, and muscle weakness. In making the diagnosis of GD, 2 tests are carried out, namely a thyroid function test which consists of examinations to diagnose hypothyroidism, namely Wayne index scoring, TSH test, and FT4 as well as tests to distinguish GD from other causes of hyperthyroidism, namely TRab, radioactive iodine uptake scan with I-123 or I-131, thyroid ultrasound with doppler, T3/T4 ratio values, and CT or MRI. The goal of treatment for GD is to control and improve the condition based on the pathophysiology of GD, namely the antigen-antibody reaction in the thyroid gland. Modalities for the treatment of GD consist of anti-thyroid drugs, surgery, and radioactive iodine (RAI) treatment with sodium-131(131I). The choice of treatment is based on the severity of thyrotoxicosis, age, thyroid size, availability of modalities, response to treatment, and other comorbidities.
Varises Esofagus Shofa Rona Alya Nuha; Ratu Asyifa Sukma Ayu; Sastraningsih Setiawati; Suci Nurjanah; Yusra Pintaningrum
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2762

Abstract

Varises esofagus adalah pelebaran vena submucosa pada distal esofagus akibat hipertensi portal pada pasien sirosis hati. Varises esofagus merupakan salah satu bentuk komplikasi dari penyakit sirosis hati, yaitu penyakti gambaran perubahan patologis dari stadium akhir fibrosis hepatik yang berlangsung progresif dan ditandai dengan terbentuknya nodul regenerative. Terdapat beberapa terapi yang dapat diberikan kepada pasien dengan varises esofagus, seperti terapi farmakologi dan terapi endoskopi dilakukan terutama untuk upaya mencapai homeostatis pada kasus perdarahan varises. Terapi endoskopi terdiri dari skleroterapi dan ligasi. Skleroterapi adalah metode pengobatan dimana agen sklerosis (etanolamina oleat) akan disuntikkan ke dalam varises untuk menghambat hemodinamik. Sebaliknya, teknik ligasi dilakukan untuk memblokir aliran darah varises secara fisik dan memicu fibrosis
Dinamika Psikologis Pelaku Kekerasan Seksual pada Anak Kayla, Baiq Ghassani; Ali Ramzi; Febbi Anggy; Herodya L Fesmia; Pujiarrohman
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2774

Abstract

Nowadays cases of sexual violence against children are rife in Indonesia. Cases of sexual violence increase over time. The perpetrators of sexual violence are not only strangers who are not known to the victim, but also the closest people to the victim, such as fathers, uncles, or grandfathers. Ironically, perpetrators of sexual violence in children today are not only carried out by adults, but also carried out by children. The types of perpetrators of sexual violence have also varied greatly, such as perpetrators of rape to perpetrators of internet sexual violence who distribute pornographic content. There are several psychological factors that underlie the perpetrators of sexual violence, such as lack of parental attention, lack of education about intimate organs, to easy access to pornographic photos or films on the internet. There are two factors that cause a person to become a perpetrator of sexual violence, first is historical factors, such as a history of past trauma and second is psychological factors, such as lack of interpersonal communication. Perpetrators of sexual violence in children must get a treatment to overcome the problems experienced. This handling must be carried out by all groups, both from the family, community, and government. Therefore, this article will discuss the psychological dynamics of perpetrators of sexual violence in children, which includes the types of perpetrators of sexual violence, the pathophysiology of psychological dynamics of perpetrators, and efforts to handle perpetrators of sexual violence.
Diabetes Melitus Tipe 2 dengan Hipertiroid dan Hipertensi: Case Report Akelba, Shalsa Damai; Putu Wika Pramesti Iswari; Adam Trojan Alisyahbana; Aulia Dwi Hendriani; Baiq Ramdhani Amelia Negara; Grandis Cristagalli1, Izza Mufida; M. Andre Darmawan; Nadia Safira; Ni Putu Visty Wedhiani; Rike Delya Rizqina; Tri Sastra Pradhini; Indah Sapta Wardani
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2782

Abstract

Diabetes mellitus (DM) is high levels of glucose in the blood (hyperglycemia) accompanied by disturbances in carbohydrate, lipid, protein metabolism as a result of insufficiency of insulin function which can be caused by impaired or deficient insulin production by beta cells in the pancreas or can also be caused by a lack of responsiveness of insulin cells. The prevalence of diabetes mellitus is 9.3% or around 463 million people suffer from diabetes in 2019. One of the risk factors for diabetes mellitus is hyperthyroidism and hypertension. The right treatment for patients suffering from type 2 diabetes mellitus with hyperthyroidism and hypertension is to reduce glucose levels, blood pressure, and reduce the production of the thyroid gland
Potensi Kurkumin pada Kunyit (Curcuma Longa sp.) dalam Penatalaksanaan Malaria Fahira, Moona; Muhammad Andre Darmawan; Muhammad Rivandha Islami Yoga Pratama; Muhammad Renaldi Irawan; Nadia Safira; Mahacita Andanalusia
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2790

Abstract

Penyakit malaria adalah salah satu penyakit endemis mematikan di dunia yang ada di beberapa wilayah tropis seperti Asia. Malaria adalah penyakit yang disebabkan oleh parasit dari genus “Plasmodium”. Parasit tersebut ditularkan melalui gigitan dari nyamuk Anopheles betina. Berbagai obat konvensional anti-malaria seperti klorokuin, sulfadoksin, kina dan artemisinin telah menunjukkan resistensinya, sehingga diperlukan obat alternatif baru. Di Indonesia, beberapa wilayah endemis malaria seperti Jambi dan Maluku menggunakan obat tradisional bahan tanaman kunyit sebagai anti-malaria. Curcuma longa atau kunyit mengandung senyawa kurkumin yang memiliki campuran dari tiga kurkuminoid, yaitu kurkumin (77%), bisdemethoxycurcumin (3%), dan demethoxycurcumin (17%) dan memiliki beberapa target senyawa aktif. Contoh dari target senyawa aktif dari kurkumin yaitu CD36 yang dapat meningkatkan fagositosis eritrosit yang telah terinfeksi parasit dan PfGCN5 yang menginduksi kerusakan pada DNA akibat parasit malaria. Studi in-vitro dan in-vivo dari kurkumin menunjukkan hasil yang positif, pada in-vivo kurkumin sebagai anti-oksidan mengurangi parasitemia darah hingga 80–90%. Berdasarkan studi tersebut kunyit sangat berpotensi dalam tata laksana anti-malaria di masa depan.
Thyroid Cancer : an Overview of Epidemiology, Risk Factor, and Treatment Arista, Rida Dwi; Khaula Karima; M. Fardi Anugrah; Puji Widyastuti; Eva Triani
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2791

Abstract

Thyroid cancer is the most common cancer of the endocrine glands with a prevalence of approximately 95% of all malignancies. Its incidence has increased more rapidly since the 1990s than any other cancer. Thyroid cancer is divided into 4 types based on its histopathology. The nature of this cancer varies, ranging from slow progressive to aggressive. Like other cancers, thyroid cancer if left untreated will invade other organs of thebody. We collect several reading journals that discuss epidemiology, risk factors, management for thyroid gland cancer and present them descriptively. The purpose of writing this article is to discuss the latest epidemiology and risk factors that influence the incidence of thyroid cancer as well as the old and newest treatments in treating thyroid cancer. The results of this article found several risk factors thought to influence prevalence, namely radiation exposure, genetic mutation, heredity, iodine deficiency, increased TSH, autoimmune, thyroid nodules, environment, lifestyle, and estrogen. Treatments that need to be carried out are surgery, RAI therapy, thyroid hormone therapy, external radiation, systemic chemotherapy, and combination therapy. Through this discussion, it is hoped that it can become material for analysis and reference in the treatment of thyroid gland cancer. Keyword : Thyroid cancer, epidemiology, risk factor, and treatment
Potensi Senyawa Kuersetin dalam Daun Jambu Biji (Psidium guajava L.) sebagai Pengobatan Demam Berdarah Dengue Safitri, Nasywa Aulia; Marwa Zileikhadira Manzalina; Muhammad Farras Abiyyu F; Nasyada Fadhila Rahmadini; Mahacita Andanalusia
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2851

Abstract

Abstract: Dengue is one of the most common mosquito-borne diseases in tropical and subtropical climates. So far there are no effective antivirals available for the treatment of DENV infection, which in this case requires alternative treatments that can be a cure as well as prevention for dengue fever. Alternative treatment that can be used is by using plants, one of which is guava. In guava leaves, there are various compounds that are efficacious as anti-dengue fever, namely flavonoid compounds such as quercetin and tannins which are believed to inhibit the growth of dengue viruses. The purpose of writing this manuscript is to discuss the potential of quercetin compounds in guava leaves in the management of dengue fever. Keywords: Dengue hemorrhagic fever, alternative medicine, antiviral, guava leaf, quercetin, ethnomedicine

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