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INDONESIA
Jurnal Kesehatan Andalas
Published by Universitas Andalas
ISSN : 23017406     EISSN : 26151138     DOI : -
Core Subject : Health,
Health Professions
Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas Andalas.
Arjuna Subject : -
Articles 1,294 Documents
 118   119   120   121   122 
Uji Kesesuaian Hasil Pemeriksaan Sedimen Urine Metode Shih-Yung pada Volume Urine 10 mL dan 5 mL Niawaty, Putri; Rikarni, Rikarni; Yulia, Dwi
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1721

Abstract

Microscopic examination of urine sediment using shih-yung system requires 10ml urine volume. Pediatric patients and kidney disease patients with oliguria difficult to get 10mL urine samples, so it needs to be studied to determine the accuracy of results with smaller sample volumes. Objectives: To analyze agreement of urine sediment examination using Shih-yung system in 10 mL and 5 mL urine volume. Methods: This study was a cross-sectional analysis of 37 urine specimens that met inclusion and exclusion criteria at the central laboratory of Dr. M. Djamil Hospital from July to September 2020. Examination of erythrocyte sediment, leukocyte sediment, and non-hyaline cast using Shih-yung system was done in 10 mL and 5 mL urine volume. Data were analyzed using kappa reliability/agreement test and significant if p<0.05. Results: Agreement test of erythrocyte sediment examination using Shih-yung system in 10ml and 5mL urine volume were moderate significantly (κ=0.600; p<0.05), agreement of leukocyte sediment examination were moderate significantly (κ=0.571; p<0.05), and agreement of nonhialin cast examination were substantial significantly (κ=0.767; p<0.05). Conclusion: Agreement test of erythrocyte and leukocyte sediment examination in 10ml and 5mL urine volume is moderate, so 5ml urine volume was not recommended. Manual examination with microscope and difference in urine sample volume causing difference sediment concentration and amount of sediment per microscope field of view.Keywords: Shih-yung,  urine sediment,  urine volume
Gambaran Pemeriksaan Kadar SGOT, SGPT, Ureum dan Kreatinin Pasien Covid-19 dengan dan tanpa Komorbid Fadillah, Rachmi; Nasrul, Ellyza; Prihandani, Tuty
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1722

Abstract

Coronavirus disease (COVID-19) causes damage through mechanisms: cytotoxic to the bile duct, liver and renal tubular epithelial cells; severe inflammatory response due to excessive pro-inflammatory cytokines (cytokine storm); tissue anoxia; and drug-induced liver and kidney damage. AST and ALT enzymes are used to determine liver damage, while kidney damage is examined from increased urea and creatinine levels. Objectives: To know AST, ALT, urea and creatinine levels in COVID-19 patients with and without comorbidity in RSUP Dr. M. Djamil Padang. Methods: A retrospective descriptive study was conducted by taking chemical data for COVID-19 patients with and without comorbidity for March-August 2020. AST and ALT levels were examined by using an automatic chemistry analyzer with NADH method (without P-5'-P), urea with enzymatic colorimetry, and creatinine with Jaffe's modification. The data was presented in table and average (standard deviation). Results:  A study of 76 patients found 28 with comorbidity and 48 without comorbidity. Patients with comorbidity AST in average was 33.0 (20.3) U/l; SGPT 29.0 (23.4) U/l; urea 58.3 (66.9) mg/dl; and creatinine 3.0 (5.1) mg/dl. Patients without comorbidity AST in average 31.9 (28.7) mg/dl; SGPT 28.8 (21.4) mg/dl; urea 24.6 (20.1) mg/dl; creatinine 0.9 (0.4) mg/dl. In average, AST and ALT in patients with and without comorbidity were in the normal range. Urea and creatinine in patients with comorbidity were higher than normal. Conclusion: Covid-19 patients with comorbidity at admission had urea and creatinine levels in average higher than normal values.Keywords: aminotransaminase, COVID-19, creatinine
Limfopenia dan Rasio Neutrofil-Limfosit pada Infeksi Severe Acute Respiratory Syndrome Coronavirus 2 Yufani, Hevrina; Rikarni, Rikarni; Rofinda, Zelly Dia
Jurnal Kesehatan Andalas Vol. 10 No. 3 (2021): Online November 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i3.1734

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause cytokine storm characterized by the excessive release of pro-inflammatory cytokines, leading to lymphopenia and neutrophilia. Lymphopenia and high Neutrophil-Lymphocyte Ratio (NLR) on admission were associated with the severity of the disease. Objectives: To found out lymphopenia and high NLR in SARS-CoV-2 infection. Methods: This was a cross-sectional descriptive study on all patients infected with SARS-CoV-2 who met the inclusion and exclusion criteria at Dr. M. Djamil Hospital Padang from March until August 2020. Lymphocyte count and neutrophil count on admission were examined by flowcytometry method and NLR was calculated. Lymphopenia is a lymphocyte count of <1.5x103/mm3 and high NLR is ≥ 3.13.  Results: The study samples were 123 patients, with 58.5% women. The mean age was 47.80 (15.59) years. Lymphopenia was present in 39% of patients with mean lymphocyte count was 1.84 (0.83) x103/mm3. High NLR was present in 48% of patients with a mean NLR was 5.06 (4.87). Conclusion: Lymphopenia was present in 39% of patients infected with SARS-CoV-2 and high NLR was present in 48% of patients infected with SARS-CoV-2.Keywords:  lymphopenia, neutrophil-lymphocyte ratio, SARS-CoV-2
Hubungan Nilai Laju Endap Darah (LED) dengan Kadar C-Reactive Protein (C-RP) pada Pasien Positif Covid-19 Tsamarah, Yumna Tahani; Danuyanti, I Gusti Ayu Nyoman; Zaetun, Siti
Jurnal Kesehatan Andalas Vol. 10 No. 3 (2021): Online November 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i3.1771

Abstract

SARS-CoV-2 infection is a systemic infection that significantly affects hematopoiesis and the patient's immune response. Drastic increase in the production of proinflammatory cytokines like interleukin-6 (IL-6) play a role in mechanism of lymphopenia in COVID-19. Some indicators of inflammation markers include Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP). Objectives: To determined the correlation between Erythrocyte sedimentation rate (ESR) and C-Reactive Protein (C-RP) levels in patients with covid-19. Methods: This research was an analytic observational study with a cross-sectional approach. The samples in this research were 10 ESR and 10 CRP data in a patient with positive COVID-19 at the Mataram University Hospital. Results: A minimum value of 0.50 was obtained from 10 samples of CRP examination, while the maximum value was 79.90 with an average value of 32.24 and a standard deviation of 30.36. The Erythrocyte sedimentation rate (ESR) examination obtained a minimum value of 6.00 from 10 samples, while the maximum value was 103.00 with an average value of 53.60 and a standard deviation of 36.40. Conclusion: There is no correlation between the value of Erythrocyte sedimentation rate and C-Reactive Protein levels in patients with Covid-19.Keywords: Covid-19,  C-reactive protein, erythrocyte sedimentation rate 
Junctional Bradikardia pada Pasien Hiperkalemia Suwari, Cokorda Istri Padmi; Puradipa, Bayu; Wulandari, Ni Luh Eka Sriayu
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1772

Abstract

Hyperkalemia is a life-threatening electrolyte abnormality resulting in cardiac arrhythmia. Hyperkalemia may also cause bradycardia with junctional rhythm. However, the prevalence of hyperkalemia accompanying symptomatic bradycardia has only been explored in a few case reports. Thus we present a case of hyperkalemia with uncommon ECG findings. It has been reported that a 76 years old woman with type 2 diabetes mellitus, hyperkalemia and suspected coronary artery disease complaining about palpitation. Electrocardiography (ECG) showed junctional bradycardia with tall T wave and laboratory examination showed mild hyperkalemia (5.8 mmol/L). After one day of observation, severe hypotension was detected. Unexpectedly the cardiac rhythm was returned into the sinus after correction of hyperkalemia using calcium gluconate, insulin, dextrose, and salbutamol. As serum potassium level rises, sinoatrial and atrioventricular conduction was blocked, causing escape rhythm (junctional escape rhythm). In hyperkalemia, cardiotoxicity can be caused by an increase in resting membrane potential, decreased depolarization and duration of depolarization. When detected on ECG, hyperkalemia should be treated urgently and important to identify underlying causes or precipitating factors of hyperkalemia. Sinus node dysfunction is not excluded in this case.  Hyperkalemia can present a bradycardia junctional rhythm. Although the increasing serum potassium levels were low, hyperkalemia may have affected the conduction system leading to the ECG changes.Keywords:  hyperkalemia, junctional bradycardia, symptomatic bradycardia
Efek Suplementasi Selenium terhadap Marker Darah Pasca Cedera Kontusio Daba, Mariel; Goenawan, Hanna; Tarawan, Vita Murniati; Rosdianto, Aziis Mardanarian; Lesmana, Ronny
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1787

Abstract

Selenium is a trace element that has antioxidant properties and is a component of selenoproteins. In certain circumstances, such as injury, selenium supplementation is required to regulate the inflammatory response. Contusion injury increases the inflammatory response to a muscle or tissue that begins with vasodilation, increases blood flow, increases vascular permeability, and leads to edema formation at the site of injury. Objectives: To determine the effect of selenium supplementation on changes in blood markers in rats treated with contusion injury. Methods: Experimental design, using experimental male rats (Rattus norwegius), eight weeks old, weighing 200-220 grams, divided into three groups, namely: The Control group, the contusion group, the contusion + Selenium group. Selenium supplementation was given orally on days 1-3 after injury at a dose of 0.0153 mg into 2% PGA. Examination of markers such as White Blood cells (WBC), lymphocytes, monocytes, and neutrophils was carried out on day three after treatment. Results: This study found that the administration of post-muscular selenium supplementation based on examination of blood markers such as WBC, Lymphocytes, Monocytes was higher in the contusion group and lower in the selenium group. Neutrophils were higher in the contusion and selenium groups. This was not significantly different from the control group. The result of blood marker examination tended to change, but it was not statistically significant. Conclusion: Selenium supplementation in post-contusive injury mice did not provide significant changes in blood markers such as WBC, lymphocytes, monocytes, and neutrophils.Keywords:  antioxidant, blood marker, contusion, selenium
Gambaran Drug Related Problems (DRPs) Terapi Farmakologi Pasien ISPA Pediatrik di Rumah Sakit PKU Muhammadiyah Gamping Yogyakarta Husna, Nadia; Padmasari, Siwi
Jurnal Kesehatan Andalas Vol. 10 No. 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i2.1790

Abstract

Acute Respiratory Infection has become the major cause of death in children in developing countries. There were about 11.9 million episodes of severe acute lower respiratory infection that resulted in hospital admission in young children worldwide. The method of drug administered was the common Drug-Related Problems found in young children. Objectives: To evaluated Drug-Related Problems of Acute Respiratory Infection drug therapy in pediatric patients. Methods: Ninety-four pediatric patients were included in this study. Drug therapy data were obtained from medical records from January 2018 until July 2019, as this study was using a retrospective method. Drug-Related Problems of drug therapy were analyzed based on the Cipolle classification system. Results: Prevalence of female and male patients are in the same number (50%) with the highest prevalence on 2-11 years (72.34%) in young children. The number of Drug-Related Problems was found about 61.49% from 148 numbers of used drugs with improper drug selection as the major Drug Related Problems (51,65%)  followed by drugs without indication and underdose by 23.08% and 15.38%, respectively.Keywords:  acute respiratory infection, hospital, pediatrics, pharmacologic therapy
Hubungan Titer Widal Dengan Jumlah dan Indeks Trombosit Penderita Demam Tifoid di Puskesmas Wilayah Lombok Barat Widary, Baiq Larasati; Danuyanti, I Gusti Ayu Nyoman; Zaetun, Siti
Jurnal Kesehatan Andalas Vol. 10 No. 3 (2021): Online November 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i3.1792

Abstract

The diagnosis of typhoid fever can be made by hematological examination and the Widal method. Hematologic change that often occurs in typhoid fever is thrombocytopenia. Platelet function can be observed by examining the platelet index, namely the Mean Platelet Volume (MPV), and Platelet Distribution Width (PDW). The titer on the serological examination of the Widal test is a significant diagnostic for infections caused by the bacterium Salmonella typhi. Objectives: To determine the relationship between the Widal titer and the number and index of platelets in patients with typhoid fever at the West Lombok Health Center. Methods: The research methodology used is an analytic observational method with a cross-sectional approach. This study was conducted from February 2021 to April 2021. The population in this study was all patients who underwent laboratory examinations diagnosed as positive for typhoid fever in the Gunungsari Health Center, West Lombok Regency, with a sample of 24 respondents. Data analysis using Spearman correlation. Results: Statistical test results obtained P≥0.05, namely the titer value against platelets p=0.429, the titer against the MPV platelet index p=1,000, PDW p=0.291. Conclusion: there is no relationship between widal titer to the number of platelets and the platelet index in patients with typhoid fever.Keywords:  typhoid fever, platelets, platelet  index, widal titer
Malnutrisi Energi Protein Berat: Laporan Kasus Hsieh, Peter Prayogo; Wijaya, Putri Dariyanti; Aziana, Putri; Purnomo, Prahara Wahyu; Radhiah, Sitti
Jurnal Kesehatan Andalas Vol. 10 No. 3 (2021): Online November 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i3.1799

Abstract

ABSTRAKLatar Belakang: Malnutrisi pada balita masih merupakan masalah kesehatan di Indonesia dan erat kaitannya dengan perawatan rumah sakit. Laporan kasus ini ditulis untuk memberi gambaran mengenai kasus gizi buruk sehingga semakin ditingkatkannya perhatian terhadap gizi anak oleh para tenaga kesehatan di lapangan.Kasus: Anak perempuan berusia 12 bulan datang dengan keluhan sudah 1 bulan berat badan tidak bertambah dan nafsu makan berkurang. Keluhan disertai batuk dan pilek  berulang serta demam. Ayah dan ibu merupakan keluarga dengan perekonomian menengah ke bawah sehingga anak hanya diberi makan seadanya. Pada pemeriksaan fisik, anak sadar, tampak sangat kurus dan sakit sedang, didapatkan berat badan menurut usia, panjang badan menurut usia, berat badan menurut panjang badan di bawah -3 SD grafik pertumbuhan WHO. Pemeriksaan toraks menunjukkan kecurigaan terhadap infeksi pada paru kanan. Hasil laboratorium menunjukkan anemia defisiensi besi dengan peningkatan CRP dan foto toraks memperlihatkan adanya infiltrat pada paru kanan. Anak dirawat di rumah sakit dengan pemberian terapi cairan, antibiotik, dan intervensi diet. Dalam 2 minggu keadaan anak menujukkan perbaikan yang bermakna dan dapat dipulangkan dengan memberi edukasi terkait gizi anak, perilaku hidup bersih dan sehat, serta pentingnya imunisasi.Simpulan: Gizi buruk pada balita harus menjadi perhatian karena 1000 hari pertama kehidupan merupakan periode perkembangan otak yang paling pesat. Pemahaman yang baik oleh tenaga medis di lapangan mengenai gizi anak sangat diperlukan dalam rangka memberi edukasi kepada masyarakat untuk mengurangi angka kejadian gizi buruk pada balita Indonesia.Kata kunci: Gizi buruk, balita, edukasi ABSTRACTIntroduction: Malnutrition in toddlers is still a problem in Indonesia and is related to hospitalization. This case is written to give an overview about severe malnutrition in children so that we, as healthcare workers will be more aware to children’s nutrition.Case: Twelve – month – old baby girl came with chief complaint of difficulty in gaining weight. This complaint was accompanied by reduced appetite and fever with repeated cough and cold. Her parents were from middle – to low – income family so this baby wasn’t fed well. On examination, she looked extremely thin. She was alert with weight – for – age, height – for – age, and weight – for – height <3 Z – score WHO growth chart. Thoracal examinations showed abnormalities on right chest. Laboratory findings showed anemia hypochromic microcytic and increased CRP. Chest radiograph showed infiltrates on right lung. She was hospitalized and treated with fluid therapy, antibiotic, and diet intervention. After 2 weeks, her conditions improved and she was discharged. Her parents were educated about feeding practices in children, hygiene, and the importance of immunization.Conclusion: Malnutrition in toddlers has to be a concern because the first 1000 days are the most dramatic phase of neurobehavioral development. Understanding children’s nutrition is essential to all healthcare workers in order to decrease the incidence of malnutrition in Indonesia.Keywords: Malnutrition, children, education
Eumisetoma pada Toraks dan Abdomen: Suatu Kasus Jarang Fran, Jimy; Fiatiningsih, Istiana; Romus, Ilhami
Jurnal Kesehatan Andalas Vol. 10 No. 3 (2021): Online November 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v10i3.1803

Abstract

Mycetoma is a chronic granulomatous infectious disease of the skin, subcutis, fascia and bones caused by bacteria (actinomycetoma) or fungi (eumycetoma) in adults aged 20-40 years old, male to female ratio is 3,7:1 respectively. The clinical finding is a painless, solid and cold subcutaneous node. It has been reported a 43-year-old woman with a painless suppurative lump in her chest, stomach, armpits and legs in the past year. The lump were hypertrophic scars, atrophic scars, nodules and erythematous papules with pustules and sinuses, which excretes exudate greenish-yellow. The patient had a history of working in an oil palm farm. Histopathological examination of hematoxylin-eosin showed suppurative granulomatous inflammation consisting of epitheloid histiocytes, solid lymphocytes and neutrophils, and datia cells. PAS (Periodic acid-Schiff) staining showed positive results. The diagnosis of deep mycosis eumycetoma was confirmed based on physical examination and histopathological examination. Eumycetoma is a rare deep fungal disease. Supporting investigations such as direct microscopy, histopathology with biopsy, and culture are needed to establish the diagnosis. The therapies are antifungal drugs and surgery. Death is possible if the infection occurs in the chest or head cavity.Keywords: deep mycosis, eumycetoma, granules, mycetoma, sinuses

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