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Efficacy of Autologous Platelet-Rich Plasma (PRP) on Perineal Wound Healing: A Controlled Non-Randomized Clinical Trial. Fadli, Muhammad; Utama, Bobby Indra; Ali, Hirowati
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.153-162.2026

Abstract

Introduction: Perineal wounds are a very common complication of vaginal birth. Perineal trauma associated with childbirth is defined as damage to the skin, perineal muscles, as well as the sphincter and anal epithelium complex. This study aims to determine the effect of PRP use on perineal wounds.  Method: A single-center, controlled, non-randomized, non-blinded clinical trial was designed in patients with perineal wounds after vaginal delivery. PRP was taken from each patient's serum (autologous). Perineal wound healing after intervention was assessed using the Redness, Oedema, Ecchymosis, Discharge, Approximation (REEDA) scale. Perineal wound pain was assessed using the Visual Analog Scale (VAS). Result: The current study involved 56 samples, 28 people per group. The average age of the patients was 28.38 ± 6.280 years. The highest education was high school, 42.9%, while the lowest was elementary school (21.4%). The highest VAS scale was 3 (42.9%) and the lowest was 1 (5.4%). The prevalence of the highest degree of perineal wounds in general was degree 2 (98.2%). The highest score was in the moderately healed group on PRP administration (92.9%). In contrast to the control group, the mildly healed category was 21.4% and not healed 14.4%.  Conclusion: There is a significant relationship between the PRP to healing perineal wounds in vaginal delivery patients at the Seberang Padang Health
Identification of Gender in Early Pregnancy Using Cell-Free Fetal Dna Hermawan, Budi Junio; Utama, Bobby Indra; Putra, Andani Eka
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.135-144.2026

Abstract

Introduction: Traditionally, chorionic villus sampling and amniocentesis can be used to help identify fetal gender around 11 weeks of pregnancy. However, the risk of miscarriage with these procedures is approximately 1 to 3%. The discovery of cell-free fetal DNA (cffDNA) fragments in the plasma and serum of pregnant women carrying male fetuses has made reliable and accurate diagnosis using non-invasive procedures an option for determining fetal gender. To determine the success rate of fetal gender identification in early pregnancy using Cell Free Fetal DNA. Methods: An analytical observational research method to identify fetal gender in early pregnancy through Cell Free Fetal DNA examination in maternal blood. A total of 70 samples were collected using quota sampling technique. Data analysis was performed using sensitivity and specificity tests, as well as cross-sectional analysis to determine the relationship between PCR test results and gender at birth.      Results: The PCR test has low sensitivity (14.29%), meaning the test is less effective in correctly detecting male gender, resulting in many false negatives. However, it has high specificity (98.11%), indicating its excellent ability to detect female gender with very few false positives. Additionally, the Pearson Chi-Square statistical test resulted in a p-value of 0.033 (p < 0.05), indicating a statistically significant relationship between PCR test results and gender at birth.   Conclusion: Statistically, this test is better at identifying females than males, with a lower error rate for females.  
Treatment of Prepubertal Labial Adhesion: A Case Report Khalilullah, Ibnuzaer; Utama, Bobby Indra; Sari, Yulia Margaretta
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.179-186.2026

Abstract

Introduction : Labial adhesion is a condition in which the labia minora adhere to each other, either partially or completely, and is most commonly observed in prepubertal girls. The highest incidence typically occurs between the ages of 3 months and 6 years, a period during which lower estrogen levels make the vulvar mucosa more susceptible to irritation and adhesion. Objective : To report and discuss a rare case of labial adhesion on prepubertal. Methods : A prepubertal girl diagnose with labial adhesion at Dr. M. Djamil Central Hospital was reported and discuss the management. Result : A four-year-old girl was referred to the outpatient urogynecology clinic by a network hospital for labial adhesion. Upon general assessment, the child's development appeared appropriate for her age. Her medical history did not reveal any significant illnesses, surgical procedures, or history of sexual abuse, and her general physical examination was normal. Upon inspection, the labia majora were normal, but he labia minora appeared fused with a 0.2 cm gap at the proximal area of the adhesion. The adhesions appear thick and non-transparent For this patient, we decided to proceed with excision of the labial area without first attempting estrogen therapy. Seven days post-operation, the patient returned for a follow-up visit in good condition. The surgical wound was dry, urination was normal, and the examination showed a normal vaginal opening. Conclusion: From this case report, we conclude that for long-standing labial adhesion characterized by tissue thickening, labial excision is the appropriate and effective treatment option.