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Journal : Journal of Physics and Its Applications

Determination of Planning Target Volume (PTV) Margins Using Redefined Systematic and Random Error Equations from Single-Fraction Verification Data: A Case Study of Cervical Cervic Lestari, Tuti; Muttaqin, Afdhal; Hanisti, Fidhia; Diyona, Fiqi
Journal of Physics and Its Applications Vol 7, No 3 (2025): August 2025
Publisher : Diponegoro University Semarang Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpa.v7i3.24532

Abstract

This study aimed to determine the Planning Target Volume (PTV) margin by redefining the equations for systematic and random errors in a cervical cancer case. The research utilized first-fraction radiotherapy position verification data from 37 cervical cancer patients. These data comprised planned and actual positions, with the difference interpreted as the position shift. The systematic and random error equations proposed by the Royal College of Radiologists (2008) were redefined by adapting them to verification data, which were grouped into several PTV types and treated as daily fractions. The PTV margin was then calculated using formulas by Van Herk (2004), Stroom (2002), and ICRU Report 62. The results showed that the largest systematic and random errors occurred in the vertical and longitudinal directions, measuring 0.83 cm and 1.71 cm, respectively. The PTV margin calculated using the Van Herk method was comparatively larger than those obtained using the other two methods. The percentages of position shifts that exceeded the calculated PTV margins in the vertical, longitudinal, and lateral directions were 16%, 43%, and 35%, respectively. These findings indicate that the redefined equations are capable of compensating for the lack of position shift data across all radiotherapy fractions. The redefined approach can provide a more accurate estimation of PTV margins in cervical cancer treatment using single-fraction verification data. 
Co-Authors Afdhal Muttaqin Afriani, Nola Agus Irianto Alandita, Faizah Alfatini, Yumna Alisa Putri, Rahmi Amriani, Mutiara Andriziaswari, Ghina Reysa Arief Muttaqiin Armiati As-Syifa, Nisa Nur Az zahra, Firda Azeli, Jihan Azhar, Aulia Azira, Nur Azza Nuzullah Putri Azzahra, Firda Azzhara, Firda Baiq Dina Erika Wardiningtias Barthana, Diannisa Christiani Tumilisar, Christiani Citra Manela Dessi Susanti DWI CAHYANI, INTAN Eva Monalisa Vebri Kusuma Eva Monalisa Vebry Kusuma Evita Putri, Rahmah Farcham Mulloh Fatma wati Fatmawati, Fatmawati Fatmawati, Junita Febri Yanto, Febri Febrianty, Riana Fermunesti, Rasta Fiqi Diyona, Fiqi Fitri, Nurmiati Gunawan Santoso Hanisti, Fidhia Hendriyani, Riri Heru Kurniawan Idrus, Nur Istiqomah A. Kemala Sari , Widia Kessy Putri Mulya, Kessy Khairil Arif Khairun Nisa khairunnisa, kania Kurnia, Irma L. V, Yuhendri LV, Yuhendri Mailiyawati, Ghina marhamah, ithvi Monica Prima Sari muloh, farcham Nanda, Rama Nazwa Syahlilla Sudirman Nebila, Tiara Ningtyas, Ratu Dwi Notrilauvia, Nindy NURUL ANNISA Octaviani, Feni Oktafrida, Leni Oktavia, Rani Pransiska, Liya Prima Sari, Monica Primantiko, Retno Puteri, Dini Eka Putri, Biomechy Oktomalio Putri, Rahmah Evita Rahmadiyani, Rahmadiyani Rika Susanti Rini Rustini Rizkie, Ricky Rose Rahmidani Safitri, Violetta Sazaliana, Ade Sembiring, Dea Laurenta Br Siti Asiyah Skunda Diliarosta Solehun Stefvannof, Diego Syofyan, Rita Tato Saputro Wahyuni, Setio Putri Ayu Sri Wati , Fatma Wigati Asih Afiana, Selinda Y., Fitri Amanda Solta Yuliani Yuliani Yurnetti, Yurnetti Zulhanif, Halimatun Saqdiah