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All Journal Jurnal Berkala Epidemiologi Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Paediatrica Indonesiana Jurnal Medik Veteriner Journal of Midwifery Journal Of Widya Medika Junior Jurnal Widya Medika
Paul L Tahalele
Department Of Surgery, Airlangga University Medical School/Dr. Soetomo General Hospital, Surabaya, East Java
Biochemistry, Genetics & Molecular Biology Computer Science & IT Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary

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MODIFIED BUTTERFLY ANTI-TENSION TAPE AS A PREVENTION OF HYPERTROPHIC SCAR IN FACIAL REGION MEASURED BY JAPANESE SCAR SCALE (JSS) Gerardo Laksono; Herman YL Wihastyoko; Paul L Tahalele
JURNAL WIDYA MEDIKA Vol. 8 No. 1 (2022): Supplement Juni
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v8i1.4025

Abstract

Introduction: Abnormal scar remains an unsolved problem in some countries marked by an increase of prevalence of abnormal scar in the last 2 to 3 decades. Prevention of abnormal scar is essential but there aren't many therapy modalities as prevention followed by affordable prices to all society groups for abnormal scar.Purpose: to determine the effect of anti-tension tape in the shape of a butterfly as a hypertrophic scar prevention measured by Japanese Scar Scale (JSS). Method: This is an analytic study with an observational study design and a cohort study method. Total sample used in this study is 80, divided into 2 groups contains 40 patients who got anti tension tape application and patient who didn't. The anti tension tape was used for 3 months. Chi-Square was used as a statistical analysis in this study. Results: From 40 samples in anti-tension tape application group, 33 patients have normal scar, 7 patients have hypertrophic scar. From 40 patients in control group, 11 patients have normal scar and 29 patients have hypertrophic scar. Statistical analysis using chi-square showed p=0.000. Conclusion: Modified butterfly anti-tension tape can be used as on therapy modality as a prevention of Hypertrophic scar measured by Japanese Scar Scale.
POST COVID-19 SYNDROME EFFECT ON DAILY LIFE ACTIVITIES Sianty Dewi; Bernadette Dian Novita Dewi; Niluh Suwasanti; Paul L Tahalele; Evelyn Ongkodjojo; Wilson Christianto Khudrati; Kevin Samsudin; Ni Nyoman Ratih Dharmapatni; Delvi Vorst; Theresia Cindy Limantoro
JURNAL WIDYA MEDIKA Vol. 9 No. 2 (2023): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i2.5061

Abstract

The Covid-19 pandemic had a big impact on the world over the past two years., and it is estimated that 1 in 10 people have been infected. The development of prevention and treatment systems can reduce mortality, but a new problem has emerged in the group of survivors. New clinical complaints, Getting COVID-19 again or having ongoing symptoms of COVID-19 for four weeks after the first infection, can affect a wide variety of organ functions. The long-term effects of having COVID-19, like feeling tired, having trouble breathing, chest pain, difficulty thinking, and joint pain, can make life worse. The study was conducted using a qualitative descriptive method using an online questionnaire. The results showed that some residual symptoms that respondents still felt after four weeks since being infected with COVID-19, such as fatigue easily (80%), joint pain (63.3%), insomnia (56.7%), depressive symptoms (53.3%), shortness of breath (50%), impaired concentration and memory (50%), livelihood disorders (43.3%), cough (40%), respiratory disorders (36.7%), weight loss and appetite (33.3%), fever (26.7%). Overall, it was found that 20% of COVID-19 survivors experienced daily activity disruptions assessed using the Modifications of Barthel Index and EQ-5D-5L questionnaires.
Optimized RT-qPCR Detection of Hepatic Lipopolysaccharide-Binding Protein in Diet-Induced Obese Mice Tjahjono, Yudy; Wedharga, I Gede Putu Adhi; Novita, Bernadette Dian; Tahalele, Paul; Wijaya, Hendy; Soediono, Endang Isbandiati; Hendrata, Adi Pramono; Dewi, Sianty; Wijaya, Sumi; Ervina, Martha; Kuncorojakti, Suryo
Jurnal Medik Veteriner Vol. 8 No. 2 (2025): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol8.iss2.2025.308-317

Abstract

High-throughput RT-qPCR results on hepatic lipopolysaccharide-binding protein (LBP) expression in obese subjects are essential, as they reveal the endotoxin’s role in the development of obesity and non-communicable disease (NCD). This study aimed to optimize RT-qPCR detection of LBP in diet-induced obese mice. This study primarily focused on addressing high variability through reference gene normalization. A total of six male C57BL/6 mice aged 6 weeks were randomly allocated into two dietary treatments (n = 3), consisting of mice fed with the standard chow diet (SCD group) and mice fed with the high-fat and high sucrose diet (HFHS group) ad libitum for 8 weeks. Relative quantification strategies involving the standard 2-ΔΔCt method (calibrator as mean) and the modified 2-ΔΔCt method (calibrator as individual sample-matched biological replicates) were compared in terms of their variability. Obesity was successfully induced in the HFHS treatment group, as indicated by significantly higher body weight, calorie intake, and LBP relative expressions compared to the SCD group. In addition, a sample-specific calibrator approach using the modified 2-ΔΔCt method resulted in lower variability in relative gene expression levels. A modified 2-ΔΔCt method, which utilizes a sample-specific calibrator to counteract sample-specific variability, was successfully employed to address high variability in RT-qPCR results.
HYPOGLYCEMIC, ANTI-INFLAMMATORY EFFECT OF PORANG (AMORPHOPHALLUS ONCHOPYLLUS) ON ALLOXAN-INDUCED DIABETIC RATS Young, Andre; Novita, Bernadette Dian; Ricardo, Evan; Dewi, I.G.A.P.D; Amadeo, Jovan; Dewi, Sianty; Tahalele, Paul
JURNAL WIDYA MEDIKA Vol. 9 No. 1 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v9i1.4173

Abstract

Introduction: Iles-iles / Porang is a tuber-producing plant that is commonly found in Indonesia. One of the most sought after content from Porang is Glucomannan. One of Porang’s health benefit is related to the effect of lowering blood glucose levels because it can prevent glucose absorption. These benefit is interesting to study because there has been no research linking the use of Porang to reduce inflammatory process in hyperglycmic conditions. Purpose: This study aims to analyze the anti-inflammatory, anti-oxidant and hypoglycemis effects of Glucomannan from Porang (Amorphophallus onchophyllus) extract in experimental animals. Method: The research design was a true experimental post-test only control group with random sampling to determine 5 white rats into the normal group, positive control group, negative control group and treatment 1, 2 and 3. The positive control group received Acarbose therapy thile the negative control group received carboxy-methyl-cellulose (CMC) therapy. This study used Porang extract (Amorphophallus onchophyllus) with concentrations of 200, 400 and 800 mg/Kg in hyperglycemic white rats that had been induced by Aloxan. The study was conducte for 50 days and then blood and serum samples were taken to assess the effect of hypoglycemia, anti-inflammatory and anti-oxidant using blood glucose, Malondialdehyde and C-reactiveprotein (CRP) measurement. Result and Discussion: The results showed no significant difference between the groups of rats receiving Porang extract and the positive and negative control groups. However, the MDA levels after 50 days of intervention between the negative control group and the therapy with doses of 200, 400 and 800 mg/Kg showed significant differences. Similarly found for blood glucose levels after intervention between negative control group and the 200 and 400 mg/Kg therapy group. This results may be caused by the type of Porang used, the form of the Porang and the concentration level of the Porang extract. Conclusion: Porang with the type of Amorphophallus onchophyllus can’t be used directly, but requires further processing to obtain the active substance Glucomannan.
Tackling Pediatric Obesity: Overcoming Challenges and Implementing Effective Management Practices Angelina, Zenia; Tahalele, Paul L; Samsudin, Kevin; Ludia, Grace Margaretha; Gumelar, Agustinus Bimo
Journal of Midwifery Vol. 9 No. 2 (2024): Published on Desember 2024
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.9.2.67-79.2024

Abstract

Obesity is described as an excess of adipose tissue accumulating in a body. Obesity can occur at any age, including pediatrics. In addition to the related health problems, obesity in children can increase the risk of developing chronic diseases. This literature review was carried out using search engines PubMed, Elsevier and Google Scholar, limiting the last 5 years to articles from 2019 to 2024. The main intervention to overcome pediatric obesity is dietary intervention, but a combination with other interventions such as physical activity, behavioral adjustments, and parental support may be more effective. With early intervention, pediatric obesity can be managed well
A Comprehensive Review: Plantar Fasciitis in Geriatric Patients in Indonesia: Ulasan Komprehensif: Fasciitis Plantaris pada Pasien Geriatri di Indonesia Henry Ricardo Handoyo; Paul L Tahalele; Andre Young; Kevin Samsudin; Yovita Vivi Megasari; Gumelar, Agustinus Bimo; Ageng Salmanarrizqie
Journal of Midwifery Vol. 10 No. 1 (2025): Published on June 2025
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.10.1.16-30.2025

Abstract

Plantar fasciitis is a degenerative condition affecting the connective tissue in the heel, characterized by pain at the medial plantar tuberosity of the calcaneus. It commonly occurs in elderly individuals aged 60 and above, with most cases resolving without treatment. However, therapeutic options become limited for older patients, particularly those aged 40 and above. This study evaluates various treatment methods for geriatric patients with plantar fasciitis, focusing on both medical and non-medical approaches. A comprehensive review of 19 relevant journals from 2000 to 2024 was conducted, analyzing treatments and their effectiveness in elderly populations. The results consistently demonstrated that Platelet-Rich Plasma (PRP) injections were highly effective in treating plantar fasciitis in elderly patients. No non-injection treatments were found to surpass the efficacy of PRP. Further research is needed to explore additional effective therapies for geriatric plantar fasciitis beyond PRP.
Co-Authors Achmad Basori, Achmad Adi Nugroho Adri Gabriel Sooai Agatha Christi Palupi Ageng Salmanarrizqie Agustinus Bimo Gumelar Agustinus Bimo Gumelar Albert Setiawan Alyssa Claudia Valerie Gunawan Amadeo, Jovan Andre Young Angelina, Zenia Anggorwasito, Jose L Anggowarsito, Jose L Arief, Teuku Audrey Fedora Irawan Bernadette Dian Novita Bernadette Dian Novita Bernadette Dian Novita Bernadette Dian Novita Dewi Budipramana, Edwin Claudia Tjipto Daniel DH Silitonga Delvi Vorst Dewi, I.G.A.P.D Dhihintia Jiwangga Dhihintia Jiwangga Suta Dhihintia Jiwangga Suta Dian Putri, Maria Patricia Dorothea Kusumaningrat Dyana Sarvasti Ellenora R Mustikaningrat Ellenora R Mustikaningrat Epriyanto T Darmadi Erwin, Ferdinand Evelyn Ongkodjojo Febianingrum, Adhani Ferdinand Erwin Gerardo AK Laksono Gerardo AK Laksono Gerardo AK Laksono Gerardo AK Laksono Gerardo Axel Ruslie Gerardo Laksono Hanindita, Meta Herdiana Harijati, Erna Hendrata, Adi Pramono Hendrawan, Kevin Anggakusuma Henry Ricardo Handoyo Herman YL Wihastyoko Huang, Velinda Hutama, Andreas MS Immanuel Michael Irene L Parengkuan Jose L. Anggowarsito Joseph, Herman Kartana, Kartana Kevin Samsudin Kevin Samsudin Kevin Samsudin Khoesasih, Antonius Kevin Kuncorojakti, Suryo Laksono, Gerardo Laksono, Gerardo AK Ludia, Grace Margaretha M. Nahak, Belinda Peregrina Maria S Ganggur Martha Ervina Melvin F Gonga Merici, Angela Merlinda Dwintasari Merlinda Dwintasari Mitchell Theny Motulo, Yosis Y Nevan Go Ni Nyoman Ratih Dharmapatni Niluh Suwasanti Niluh Suwasanti Ninik Asmaningsih Soemyarso Noorlaksmiatmo, Harno Prihadi Novita, Bernadette Dian Nunung Nugroho Oktavianus Y Ampur Oktavianus Y Ampur Rahayu, Titien Ricardo, Evan Ricardo, Henry Riskky Vitria Prasetyo Samsudin, Kevin Sembiring, Yan Efrata Sianty Dewi Sianty Dewi Soebroto, Heroe Soediono, Endang Isbandiati Sumi WIjaya, Sumi Suwasanti, Niluh Theresia Cindy Limantoro Titiek Ernawati Tjahjono, Yudy Tridharmadi, Epriyanto Wahyuni Widoretno, Elisabeth Tri Wedharga, I Gede Putu Adhi Wihastyoko, HYL Wijaya, Hendy Wilson Christianto Khudrati Wismaya, IGP Wegen Y Motulo Y Motulo Young, Andre Yovita Vivi Megasari