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Musfira, Musfira
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Optimal Control of a Mathematical Model for Monkeypox Transmission in Indonesia Using the Pontryagin Maximum Principle Musfira, Musfira; Side, Syafruddin; Abdy, Muhammad; Ridho, Andi Muhammad; Supriadi, Supriadi
Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam Vol 14, No 2 (2025): September
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/sainsmat142763342025

Abstract

Abstract: The re-emergence of Monkeypox poses significant public health challenges in Indonesia. This disease continues to spread due to its zoonotic nature and the high frequency of human-animal interactions. This study aims to model the transmission dynamics of Monkeypox using the SIQR (Susceptible, Infectious, Quarantined, Recovered) framework and apply optimal control strategies through the Pantryagin Maximum Principle (PMP). Data from the Indonesian Ministry of Health were utilised for model parameterisation, with numerical simulations conducted using the fourth-order Runge-Kutta method. Control strategies included quarantine, tecovirimat, and public education. The simulation results revealed that implementing optimal control reduced the infected population by up to 75% within the first 10 months compared to scenarios without control. The basic reproduction number () was successfully reduced from 2.5 to below 1, indicating that the outbreak was controlled. Additionally, the recovery rate increased by 30%, with the susceptible population achieving a disease-free equilibrium by the eighth month. These findings highlight that mathematically-driven interventions can provide effective solutions for managing infectious diseases. It is recommended that these strategies be integrated into public health policies to optimise resource allocation. Further research is necessary to evaluate the scalability of this approach for other zoonotic diseases.
Co-Authors Ahsan Ahsan Aj, Andi Meirling Akbar, Aditya Sahrul Alfons, Alfred Benjamin Amir, Rahma Melati Annabawi, Annisa Rahma Ardianza, Reza Arnold Kabangnga Asmaidar, Asmaidar Asrawati, Nugrah Ayu, Ayu Azisah, Azisah Badjeber, Rafiq Carla Wulandari Sabandar Dardjito, Hanandyo Datuamas, Padila Zikrila A. Delaplata, Carolin Miranda Dinda, Dinda Endratno Budi Santoso Fakri, M. Nurul Flassy, Gabriel Frits D Hamna, Hamna Handayani, Nurul Nisya Hardiman Hardiman Hasan, Haidar Hasana, Hasana Hasmiati Hasmiati Herlina Ahmad, Herlina Ikbal Ikbal Indah Damayanti, Indah Indah Sari Zulfiana Indarwati Indarwati Iriyanto, Santje Magdalena Ismanto Ismanto Kaharuddin, Mutahharah Nemin Kamerop, Bernadetha Papuana Khafidah, Wahyu Khairani Khairani Kogoya, Otius Labok, Anna M Labok, Anna Mariani LUKMAN, LUKMAN Mahjum, Moh Martani, Ahmad Muhammad Abdy Muhammad Idris Muhammad Syarif, Muhammad Muhlis Muhlis Musfayu, Musfayu Mustakim Mustakim Mytra, Prima Naisyah, Sitti Nasriani Nasriani Ningsih, Andi Arda Nurmaningtyas, Anggia Riani Nursupiamin Nursupiamin, Nursupiamin Ongirwalu, Yohana Jeltty Pata, Abd. Asis Rahmadon, Rahmadon Ridho, Andi Muhammad Rismayanti Rismayanti S, Nurhidayanti. Saba, Hafiz Saputra, Ahyar Sembor, Thelly Sula Hendrina Sudarsono Supriadi Supriadi Suradi Suradi Sutji Rochaminah Syafruddin Side Syahrizal Abbas Syamsuddin, Indah TONE, KAMARUDDIN Ulpianti, Ulva Usman, Syamsudin Wahidayanti, Wahidayanti Wahyuddin Wahyuddin Wally, Johanes F Wandik, Hagar Wayan Kantun Wonua, Almansyah Rundu Yannice Luma Marnala Sitorus Yanthy, Normalia Ode