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All Journal Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Sains dan Komunitas Syntax Literate: Jurnal Ilmiah Indonesia Jurnal SOLMA JMM (Jurnal Masyarakat Mandiri) JSFK (Jurnal Sains Farmasi & Klinis) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia JCPS (Journal of Current Pharmaceutical Sciences) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Abdimas Indonesia : Jurnal Abdimas Indonesia Pharmaceutical And Biomedical Sciences Journal (PBSJ) Jurnal Pengabdian Masyarakat Bangsa Indonesian Journal of Pharmacy and Natural Product Molekul: Jurnal Ilmiah Kimia Jurnal Pengabdian Farmasi dan Sains Jurnal Abdita Naturafarm
Anisa Amalia
Department Of Pharmaceutis, Faculty Of Pharmacy And Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Delima II/IV, Jakarta Timur, Indonesia 13460
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Curcumin Transethosome Gel: Anti-inflammatory Activity Test in Carrageenan-Induced Sprague Dawley Rat Amalia, Anisa; Efendi, Kriana; Novianti, Amelia
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.005618

Abstract

Curcumin has anti-inflammatory activities, and is formulated into the transethosome (TE) system to improve penetration. The TE system's stability can be increased by incorporating it into a gel dosage form. This study aims to determine the anti-inflammatory activities of curcumin TE gel. Curcumin TE gel was produced in 3 compositions, each having a curcumin content of 10 mg (F1), 40 mg (F2), or 160 mg (F3). On TE gels, organoleptic, viscosity, pH, particle size, and zeta potential were evaluated. The test animals were divided into five groups for anti-inflammatory activity testing. A 1% carrageenan solution was used to induce edema in the animals, and the volume of edema was measured for comparison with p0.05set as significant difference. Curcumin TE gel's physical properties showed a yellow and homogenous gel with viscosity values of 31.173 – 33.626 cPs, pH 4.75 – 4.84, particle size 208.3 – 319.4 nm, and zeta potential (-) 40.03 – (-) 51.12 mV. On anti-inflammatory tests, the edema volume in the group given curcumin TE gel decreased in the 270th minute. According to statistical analysis, the test group had a significant difference (p 0.05) from negative controls and no significant difference (p 0.05) from positive controls in F1 and F2 anti-inflammatory activity. According to these results, the curcumin TE gel exhibited anti-inflammatory activity equivalent to the positive control, while F3 had anti-inflammatory activity better than the positive control. 
PELATIHAN PEMBUATAN SABUN MANDI CAIR LIDAH BUAYA SEBAGAI UPAYA KEMANDIRIAN WARGA BINAAN PANTI ASUHAN Nursal, Fith Khaira; Amalia, Anisa; Nining, Nining; Sunaryo, Hadi
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 1 (2023): Oktober 2023
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2023.v2.i1.16536

Abstract

The social problems of children with difficult economic environments or incomplete families are the concern of the government and society to overcome them. Al-Ma'un Orphanage is one of Muhammadiyah's charitable efforts as a social institution that provides religious guidance and other creativity for foster children so that they can be independent and useful for society. This orphanage fosters approximately 30 children of various ages. The aim of the foster child development system to created of independent creativity through training in making herbal liquid bath soap. Aloe vera is a plant that is easy to grow and has many benefits for skin health such as moisturizing, softening, and as an antioxidant that can inhibit the premature aging process of the skin. Training is carried out using educational and experimental methods by directly involving participants. The results of the training were measured through the evaluation of the pre-test and post-test values with significant results based on the statistical analysis of the paired t-test (p <0.05). There was a significant increase in participants' knowledge before and after the training activity. This training is not only aimed at nurturing, but also providing provisions for children so that one day they will have hope and a better future because children as God's mandate, the next generation of the nation must get the widest possible opportunity to grow and develop optimally.
Penggunaan Superdisintegrant Crospovidone Pada Sediaan Orally Disintegrating Tablet (ODT) Fitriana Priyoni, Nandhary; Prisiska, Apt. Fahjar; Amalia, Anisa
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v7i9.12839

Abstract

Orally Disintegrating Tablet (ODT) merupakan tablet yang bekerja cepat, mudah hancur dalam waktu kurang dari 60 detik, tidak meninggalkan rasa yang tidak enak di mulut ketika hancur dan praktis untuk dibawa berpergian. Komponen yang mempengaruhi waktu hancur tablet adalah superdisintegrant. Salah satu superdisintegrant yang banyak digunakan dalam pembuatan ODT adalah crospovidone. Tujuan dari studi literatur ini adalah untuk mengkaji pengaruh penggunaan crospovidone sebagai superdisintegrant terhadap sifat fisik ODT. Metode yang digunakan dalam tinjauan pustaka adalah narrative review yang mengelompokkan data – data sifat fisik ODT meliputi keseragaman bobot, keseragaman ukuran, kekerasan, kerapuhan dan waktu hancur tablet yang merupakan hasil kajian dari minimal 30 literature yang cocok dengan kriteria inklusi. Berdasarkan hasil kajian literatur diperoleh konsentrasi crospovidone yang dapat digunakan sebagai superdisintegrant pada sediaan ODT adalah 2 – 25%. Kesimpulan: Perbedaan konsentrasi crospovidone sebagai superdisintegrant pada formulasi ODT tidak mempengaruhi keseragaman bobot dan ukuran. Perbedaan konsentrasi crospovidone mempengaruhi hasil uji kekerasan, waktu hancur dan kerapuhan tablet. semakin tinggi jumlah konsentrasi crospovidone yang digunakan maka akan semakin cepat waktu hancur tablet.
Pendampingan Pendampingan Anak Didik Lembaga Pembinaan Khusus Anak (LPKA) II Bandung dalam Pengembangan Produk Sabun Amalia, Anisa; Khaira Nursal, Fith; Ridwan Zamzany, Faizal; Nining, Nining
Jurnal SOLMA Vol. 12 No. 3 (2023)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v12i3.11308

Abstract

Background: Skill development is an activity that can be provided by LPKA officers and from the wider community, such as educational institutions. One of the trainings from the Community Partnership Program (PKM) that can be taught to LPKA Students is the manufacture of household soap and efforts and strategies to market it as a home product that is not inferior in quality to industrial products. This training is expected to increase the skills of students in producing quality soap products and improve the ability of students to do marketing so that they can be used as provisions for students when returning to society. Method: Students of LPKA II Bandung as non-productive community partners are targets that have the potential to develop their skills so as to reduce the burden on the government in overcoming employment problems. The program stages consist of training in making household soap products in the form of liquid dish soap and solid soap using natural materials that are easily obtained. Indicators of success from providing this material can be known by comparing the value of test results before and after the activities obtained by participants. Results: There was a significant increase in participants' knowledge about the quality and quality of soap and product marketing techniques (p < 0.05). Conclusion: There was a significant increase in participants' knowledge about the quality and quality of soap and product marketing techniques (p < 0.05).
Effect of Cosolvent and Polymer HPMC P.603/PVA-based Lamotrigine Orodispersible Film: Optimization and Physicochemical Characterization Nining, Nining; Amalia, Anisa; Benita, Clara; Andriyani, Agnes Aga; Supandi, Supandi
Molekul Vol 20 No 3 (2025)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2025.20.3.12949

Abstract

ABSTRACT. Lamotrigine (LTG), classified as BCS class II, is dissolved in cosolvent ethanol (EtOH) or ethyl acetate (EA) to enhance solubility. The objectives of this study are to identify the appropriate formulation of LTG orodispersible film (OF) based on hydroxypropyl methylcellulose Pharmacoat® 603 and polyvinyl alcohol (HPMC P.603/PVA) polymer with EtOH or EA solvency using Central Composite Design in Response Surface Methodology (CCD-RSM). An experimental approach was utilized to investigate the effect of cosolvent amount and HPMC P.603/PVA ratios on the film disintegration time (DT) and folding endurance (FE). The optimized OF-EA composition was 0.46 HPMC P.603/PVA ratio and 3.66% EA with a desirability of 0.817. In comparison, the optimal OF-EtOH composition was 0.87 HPMC P.603/PVA ratio and 6.19% EtOH with a desirability of 0.843. The characteristic data for the optimal formulas include: OF-EtOH: weight variation 92.05±4.81 mg, thickness 0.15±0.01 mm, DT 36.11±1.48 sec, and FE 310.33±5.03; and OF-EA: weight variation 93.72±1.50 mg, thickness 0.16±0.00 mm, DT 26.73±3.32 sec, and FE 470.6±37.44. Based on the OF-EtOH FE, the HPMC P.603/PVA ratio had a greater effect compared to the amount of EtOH (p<0.05). The analysis of variance (ANOVA) demonstrated that the amount of EA had a greater impact compared to the HPMC P.603/PVA ratio, with statistical significance (p<0.05). The EtOH cosolvent was preferable to EA based on the LTG solubility and OF dissolution profile. LTG OF had favorable physicochemical properties and showed promise as a rapid-dissolving formulation for therapeutic purposes. Keywords: Central composite design, cosolvency, disintegration time, folding endurance, oral film.
Formulation and Antioxidant Evaluation of Clay Masks Containing Robusta Coffee Pulp Extract Fith Khaira Nursal; Anisa Amalia; Karsiti Karsiti; Sri Nevi Gantini
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 7 No. 2 (2025)
Publisher : Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v7i2.47124

Abstract

The pulp of robusta coffee (Coffea canephora L.) is known to contain chlorogenic acid compounds that have potential as antioxidants. The content of this compound can be utilized as an active ingredient in cosmetics such as clay masks. The main component that affects the physical properties of a clay mask is the clay base. This study aims to develop a clay mask formulation from robusta coffee pulp extract with variations in the concentration of base combinations, namely bentonite and kaolin, and to observe their effects on the physical properties of the dosage form. The base concentration variations used were 20% (F1), 25% (F2), and 30% (F3) with a bentonite to kaolin ratio of 1:2. The evaluation of physical properties included organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests, viscosity tests, and drying time measurements. The evaluation results showed that all clay masks were homogeneous with pH values ranging from 5.15 ± 0.04 to 5.29 ± 0.12, spreadability values of 4.60 ± 0.22 to 4.74 ± 0.37 cm, adhesion values of 0.82 ± 0.11 to 1.16 ± 0.15 seconds, and viscosity ranged from 5501 ± 670.22 to 7567.67 ± 220.30 mPa.s, and drying time ranged from 20.60 ± 0.39 to 25.34 ± 0.80 minutes. Results of the antioxidant activity test indicated that the clay mask made from robusta coffee pulp extract is a powerful antioxidant with IC50 values of 28.31 ± 4.72 to 30.45 ± 5.69 ppm. Variations in the concentration of the clay mask base significantly (p < 0.05) affected the viscosity and drying time of the dosage form. In summary, the clay mask formulations satisfied the essential physical criteria and showed promise for cosmetic application. F3 emerged as the leading formula, exhibiting the highest antioxidant capacity, evidenced by its lowest IC₅₀ value.
Development of Coffee Fruit Skin (Coffea canephora) formula as Antioxidant peel-off Masks. Fith Khaira Nursal; Anisa Amalia; Nining Nining; Dania Athaya Putri; Kinanti Dara Larasati
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 2 (2024): J Sains Farm Klin 11(2), August 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.2.118-126.2024

Abstract

The outer skin of robusta coffee bean (Coffea canephora) was a processing waste containing phenolic compounds with antioxidant role. This activity is relevant when used in cosmetic preparations such as peel-off masks, which form a thin elastic layer on the facial surface and are easy to remove. One of the important ingredients of peel-off masks is plasticizer such as sorbitol characterized by flexibility, not easily fragile, and elasticity. Therefore, this research aimed to develop peel-off formula from robusta coffee skin by influencing sorbitol variations on the characteristics of masks in the form of gel. A total of six gel masks formulas were made with sorbitol variations of 10%, 12.5%, and 15%. The two types of gel base used were Carbopol 940 and HPMC (Hydroxy Propyl Methyl Cellulose), at concentrations of 0.25% and 4%, respectively. The results showed that sorbitol variations affected the physical characteristics (p > 0.05) but did not influence antioxidant activity of robusta coffee skin extract peel-off masks.
Detergen Cair Ramah Lingkungan Berbasis Metil Ester Sulfonat (MES): STEM Project-Based Learning di SMA Muhammadiyah 9 Kota Bekasi Nining Nining; Yeni Yeni; Anisa Amalia
Amaliah: Jurnal Pengabdian Kepada Masyarakat Vol 8 No 1 (2024): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPI UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v8i1.2970

Abstract

One of the problems related to the issue of damage to aquatic ecosystems due to environmental pollution in Indonesia is the use of surfactant-based detergents, which make it difficult for people to degrade naturally. Making environmentally friendly liquid detergent products made from MES surfactants can be a learning experience for students using the low-carbon STEM project-based learning model concept. This model is a more practical approach to developing creative thinking skills and is part of a learning community for continuous learning. This service activity is collaborative between universities and schools in applying STEM to chemistry learning. This activity is an alternative form of learning chemistry to stimulate students' fascination and interest in learning material, which is often considered challenging. The activity method uses group simulation and experimental methods to optimize material delivery. Based on evaluation data that was paired t-tested, there was a significant increase in students' understanding of the material (p<0.05) with an increase in the average test score from 40.44 to 89.56. Apart from that, most of the activity participants also showed active participation and enthusiasm.
Co-Authors Adesi Chenia Adia Putra Wirman Alvin Integra Amelia Novianti Andriyani, Agnes Aga Ari Widayanti Astri Dian Wulandari Benita, Clara Dania Athaya Putri Dewi, Elvira Ratna Dinaianti, Adelia Edi Setiawan Efendi, Kriana Effionora Anwar Etin Diah Permanasari Fatmawati, Sofia Fith Khaira Nursal Fith Khaira Nursal Fitriana Priyoni, Nandhary Gantini, Sri Nevi Hadi Sunaryo Hariyanti Hariyanti Jannatu Yasmin Adiningsih Karsiti Karsiti Karsiti Karsiti Khaira Nursal, Fith Khalbu, M. Abdullah Khaulah, Khaulah Kinanti Dara Larasati Laszairina, Andra Yunita Mahdi Jufri Muhammad Andika Nining Nining Nining Nining, Nining Novianti, Amelia Nugrahaeni, Fitria Oktafiani, Erna Palensia, Fadhilah Prisiska, Apt. Fahjar Putri Ulan Sari Rahmah Elfiyani Rahmah Elfiyani Rahmah Elfiyani Rahmatullah, Rizki Ridwan Zamzany, Faizal Riyanto, Raditya Naufal Sri Nevi Gantini Supandi Supandi Tahyatul Bariroh Tania, Cici Yeni Yeni Yeni Yeni Yeni Yeni Yudi Srifiana Yusnia Yusnia