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EVALUATION OF COVID-19 VACCINE EFFECTIVENESS AMONG HEALTHCARE WORKERS USING CASCADE ANALYSIS Bambang Subakti Zulkarnain; Eunice Marlene Sicilia Kundiman; Lily Aina; Nanda Ardianto; Fauzul Meiliani; Melinda Putri Amelia Rachman; Fatimatuz Zahra Oviary Satryo; Pharmasinta Putri Hapsari; Arina Dery Puspitasari; Alfian Nur Rosyid; Tamara nUR Budiarti
Jurnal Kesehatan Vol 15 No 2 (2022): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v15i2.27553

Abstract

Background: Healthcare workers in Indonesia have been prioritized for vaccination. Nevertheless, fully vaccinated healthcare workers are still at risk of being infected with COVID-19, but will be less likely to develop severe symptoms, be hospitalized or be at risk for death as compared to those who have not been vaccinated. Objectives: This study aims to analyze the incidence of COVID-19 in fully vaccinated healthcare workers. Methods: This cross-sectional study was conducted in 2021. All healthcare workers who have been fully vaccinated, have recovered from COVID-19 (2-4 weeks after vaccination) and able to complete a questionnaire were the participants. The collected data was then analyzed using the cascade method. Results: Based on the 529 collected questionnaires, by using the cascade analysis conclude that the percentage of healthcare workers who have been fully vaccinated was 99%, healthcare workers who have been fully vaccinated and then infected with COVID-19 was 14%, healthcare workers who have been fully vaccinated, infected with COVID-19 and hospitalized was 4%, healthcare workers who have been fully vaccinated, exposed to COVID-19, hospitalized and experienced the long-haul effect of COVID-19 was 0%. Discussion: Health workers are still at risk of being confirmed by COVID-19, because have high risk of being exposed in the workplace. The risk of being confirmed and severity are also influenced by age, gender and comorbidities. Conclusions: Complete vaccinations of healthcare workers did not reduce their risk of being infected with COVID-19, however, it can reduce the severity and the risk of the long-haul effects.
Assessment of Antibiotic Use in ICU Patients with Pneumonia Using ATC/DDD as a Quantitative Analysis Method Mareta Rindang Andarsari; Zedny Norachuriya; Sarah Mahmudatun Nabila; Toetik Aryani; Alfian Nur Rosyid
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 9 No. 2 (2022): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v9i22022.138-145

Abstract

Background: Pneumonia is an infection of the lung tissue which is mainly caused by bacteria. High utilization and inappropriate use of antibiotics increase resistant bacteria, morbidity, mortality, and treatment cost. Quantitative evaluation becomes one of the indicators to assess the use of antibiotics which is one indicator of the quality of the antimicrobial resistance control program. Objective: This study aimed to evaluate the use of antibiotics an effort to increase the rationality of the use of antibiotics. Methods: This study was a retrospective observational study with a sampling method of time-limited sampling in Universitas Airlangga hospital from January until December 2019. Quantitatively using Anatomical Therapeutic Chemical (ATC)/Defined Daily Dose (DDD). Result: The samples obtained were 68 severe pneumonia patients who met the inclusion criteria. From the result of the study, there were 13 types of antibiotics used for pneumonia therapy, and the three most used were Levofloxacin, Ceftriaxone, and Meropenem, with a total of all antibiotics 73.64 DDD/100 patients-days. Most useful is parenteral Levofloxacin at 21.92 DDD/100 patient-days, Ceftriaxone at 20.45 DDD/100 patient-days and Meropenem at 14.29 DDD/100 patient-days. Conclusion: The DDD value indicates high antibiotic usage, but high antibiotic use does not imply unreasonable drug use, so we must undertake a qualitative review of antibiotic use.
Drug Utilization Study of Lopinavir And Ritonavir In Covid-19 Patients Aryani, Toetik; D. Puspitasari, Arina; Nafikhah, Wardah Zuhan; Rosyid, Alfian Nur; Astanti, Erika
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.598 KB) | DOI: 10.36418/syntax-literate.v7i12.10447

Abstract

The world pandemic of COVID-19 which caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a very infectious and contagious. Lopinavir and ritonavir is recommended based on guidelines from National Health Commission of China as an antiviral therapy for COVID-19. Both lopinavir and ritonavir inhibit the 3CLpro enzyme’s action, which its role in replication also release of viruses. As protease inhibitor in Human Immunodeficiency Virus (HIV), both lopinavir and ritonavir’s target is a symmetrical bag of C2 where does not exist in 3CLpro enzyme of corona virus. This literature review is needed to determine the outcome of using lopinavir and ritonavir in order to find a conclusion that can be used as a basis for intervening drug administration in patients of COVID-19. A method of narrative review was used in this study which was carried out by searching on Pubmed and Science direct. After doing abstract screening and title based on the inclusion criteria, 13 articles were left to be analyzed. These articles were analyzed using predetermined clinical outcome parameters, namely duration of hospital stay, composite event, clinical symptom score, time to achieve negative RT-PCR, duration of mechanical ventilation, and all-cause mortality. Based on all reviewed articles, the majority of clinical outcome parameters showed that the outcome was no better than standard care or other drugs. From this review, it can be concluded that lopinavir along with ritonavir provide no better clinical outcomes than standard therapy or other drugs in COVID-19’s patients.
Pelatihan Kader Tuberkulosis di Wilayah Kerja Puskesmas Bluto sebagai Upaya Penurunan Kasus Anggraini Dwi Sensusiati; Alfian Nur Rosyid; Arina Dery Puspitasari
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 2 (2023): April-Juni
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (534.375 KB) | DOI: 10.33860/pjpm.v4i2.1743

Abstract

Indonesia is the 3rd ranked country with the highest number of TB cases in the world, namely 845,000 cases in 2020. In the same year, the number of suspected TB in East Java was 42,922 cases and Sumenep Regency was in the 11th position with the most TB with 1,924 cases. Therefore, community service activities aim to carry out training for TB cadres at the Bluto Health Center as an effort to reduce TB cases. Community service activities are carried out from April to July 2022. Activities begin with planning, obtaining permits, coordination meetings, training preparations, conducting webinars, conducting face-to-face training, pre-test and post-test evaluations. Activities went well. The impact of implementing training activities was in the form of 93% of cadres experiencing an increase in knowledge and the other 7% experiencing a decrease in knowledge. These good results can be used as a basis for local health workers to continue activities to increase the knowledge and skills of cadres using the lecture method; question and answer; health promotion media in the form of videos; and direct practice. Cadres can also use the same method to educate the target community regarding TB, how to prevent and treat it.
Identification of chronic obstructive pulmonary disease using graph convolutional network in electronic nose Dava Aulia; Riyanarto Sarno; Shintami Chusnul Hidayati; Alfian Nur Rosyid; Muhammad Rivai
Indonesian Journal of Electrical Engineering and Computer Science Vol 34, No 1: April 2024
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijeecs.v34.i1.pp264-275

Abstract

Chronic obstructive pulmonary disease (COPD) is a progressive lung dysfunction that can be triggered by exposure to chemicals. This disease can be identified with spirometry, but the patient feels uncomfortable, affecting the diagnosis results. Other disease markers are being investigated, including exhaled breath. This method can be applied easily, is non-invasive, has minimal side effects, and provides accurate results. This study applies the electronic nose method to distinguish healthy people and COPD suspects using exhaled breath samples. Twenty semiconductor gas sensors combined with machine learning algorithms were employed as an electronic nose system. Experimental results show that the frequency feature of the sensor responses used by the principal component analysis (PCA) method combined with graph convolutional network (GCN) can provide the highest accuracy value of 97.5% in distinguishing between healthy and COPD subjects. This method can improve the detection performance of electronic nose systems, which can help diagnose COPD.
PROFILE OF BRONCHIAL ASTHMA PATIENTS AT A PULMONARY OUTPATIENT CLINIC OF A TERTIARY HOSPITAL IN INDONESIA Naura Alya Hirmadiani; Alfian Nur Rosyid; Budi Utomo
Majalah Biomorfologi Vol. 34 No. 1 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i1.2024.36-44

Abstract

Highlights: Budesonide-Formoterol was the most commonly prescribed medication for controlling and relieving symptoms in most individuals with bronchial asthma. Most patients reported good control of their asthma, and most also reported no subjective problems.   Abstract Background: Bronchial asthma is a common disease affecting the patient's quality of life and impacting daily life. The incidence of asthma is increasing in many countries around the world, although hospitalization and death rates due to asthma have decreased. Objective: This study aimed to explain the sociodemographic (age, sex, body mass index, smoking status) and clinical (comorbidities, subjective complaints, asthma control status, pharmacological therapy, and pharmaceutical step therapy) characteristics of bronchial asthma patients at the Pulmonary Outpatient Clinic the Universitas Airlangga Hospital, Surabaya, Indonesia. Material and Method: An analytic observational study with retrospective cross-sectional research was conducted from December 2021 to January 2023 using secondary data in medical records with total sampling as the sampling technique. Result: From 70 cases, 35 patients made the three-times visits. The majority of these patients who met the inclusion criteria were female (78.6%), 50 to 59 years old (27.1%), had class 1 obese (38.6%), non-smokers (77.1%), and had no comorbidities (28.6%). On the first, second, and third visits, the patients had no subjective complaints, had well-maintained asthma status control, used controllers and relievers in the form of Budesonide-Formoterol, and did not receive additional therapy. They had step therapy in the category of preferred controllers and relievers, steps 1–2. Conclusion: The majority of bronchial asthma patients at Universitas Airlangga Hospital, Surabaya, Indonesia, were female, aged 50–59 years, non-smokers, obese class 1, had no subjective complaints, well-controlled asthma, preferred controllers and relievers steps 1–2, using Budesonide-Formoterol as controller and reliever therapy, and did not receive additional therapy.
Integrated Care Plan In The Hospital Setting: A Scoping Review Ardi, Bangun Mukti; Nursalam, Nursalam; Rosyid, Alfian Nur
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 7 No 2 (2023): Medical Technology and Public Health Journal September 2023
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v7i2.4733

Abstract

Improving the quality of healthcare services in hospitals is one of the main goals of achieving a high-quality healthcare system. One of the efforts to enhance the quality of healthcare services in hospitals is implementing an integrated care plan. This study aims to determine the implementation of integrated care plans in hospitals. There were no limitations on methodologies, dates, or settings when reviewing papers describing qualitative or quantitative studies examining the implementation of integrated care plans in hospitals. The setting, design, and findings were all extracted from key study aspects. The major components of the integrated care plan's key components served as a framework for organizing the findings. There are 15 relevant papers published between 2018 and 2023. Most of the studies reported are qualitative, where healthcare workers reflect on their experiences and preferences regarding implementing an integrated care plan. These studies reported on issues underlying the need for the implementation of an integrated care plan, including poor administrative and management systems, lack of access, lack of coordination, lack of regulation, lack of knowledge, and lack of experience, with the ultimate goal of care being aware of cooperation and benefits for patients. An efficient way to raise patient satisfaction and improve the standard of healthcare services is to establish an Integrated Care Plan in hospitals. The efficacy and efficiency of patient care in hospitals can be improved by implementing a more structured and measurable care plan. Keywords: Integrated care plan, integrated health care systems, integrated delivery system, hospital.
FOSTERING ASTHMA AWARENESS: COMMUNITY SERVICE IN THE OCCUPATIONAL SETTING OF MANGUHARJO LUNG HOSPITAL, EAST JAVA PROVINCE, MADIUN CITY Marhana, Isnin Anang; Rosyid, Alfian Nur; Duta, Garinda Alma
Edu Dharma Journal :Jurnal penelitian dan pengabdian masyarakat Vol 8, No 2 (2024): Edu Dharma Journal: Jurnal Penelitian Dan Pengabdian Masyarakat
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/edj.v8i2.826

Abstract

                                                ABSTRACTAsthma presents a global health challenge with high morbidity and potential mortality. Data from Manguharjo Lung Hospital in Madiun (2020-2022) show a consistent rise in asthma cases and related visits. Although asthma is incurable, its management aims to control and reduce attack frequency. Varied understandings of asthma complicate patient management and control. This community service initiative aims to enhance asthma knowledge and control among patients at Manguharjo Lung Hospital. Educational and health promotion methods were employed, assessed via pre- and post-test questionnaires. Results indicate a significant knowledge increase, with post-test scores substantially higher than pre-test scores. Initially, only 30% of participants scored high on the pre-test; this figure rose to 90% post-education. This study demonstrates that the asthma awareness program significantly improved patient knowledge. This psychosocial approach is expected to enable asthma patients to become health advocates within their community.                                          ABSTRAKAsma merupakan tantangan kesehatan global dengan tingkat morbiditas yang tinggi dan potensi mortalitas. Data dari Rumah Sakit Paru Manguharjo di Madiun (2020-2022) menunjukkan peningkatan kasus asma dan kunjungan terkait setiap tahun. Meskipun asma tidak dapat disembuhkan, pengelolaannya bertujuan untuk mengendalikan dan mengurangi frekuensi serangan. Pemahaman yang beragam tentang asma mempersulit pengelolaan dan pengendalian pasien. Studi pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan dan pengendalian asma di kalangan pasien di Rumah Sakit Paru Manguharjo. Metode edukasi dan promosi kesehatan digunakan, dengan penilaian melalui kuesioner pra-tes dan pasca-tes. Hasil menunjukkan peningkatan pengetahuan yang signifikan, dengan skor pasca-tes jauh lebih tinggi dibandingkan skor pra-tes. Awalnya, hanya 30% peserta yang mendapatkan skor tinggi pada pra-tes; angka ini meningkat menjadi 90% setelah edukasi. Studi ini menunjukkan bahwa program kesadaran asma secara signifikan meningkatkan pengetahuan pasien. Pendekatan psikososial ini diharapkan dapat memungkinkan pasien asma menjadi penggerak kesehatan dalam komunitas mereka.
Terapi Montelukast pada Asma Alfian Nur Rosyid; Arief Bakhtiar; Daniel Maranatha; Muhammad Amin
MEDICINUS Vol. 37 No. 1 (2024): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/51tkjy13

Abstract

Asthma is a chronic inflammatory respiratory condition caused by various inflammatory mediators, including those from the arachidonic acid pathway, which serves as a precursor for leukotrienes and prostaglandins. Leukotriene receptor antagonists (LTRAs) have been approved since 1998 as a treatment for asthma. Montelukast is one of the LTRAs that is useful for asthma control, including cases that accompanied by allergic rhinitis. A daily dose of 5-10 mg is recommended for persistent asthma as the preferred controller. LTRAs are not recommended for acute asthma exacerbation due to their relatively slow onset, but they are beneficial in preventing exacerbations. They are also indicated for exercise-induced asthma (EIA), and can be taken 2 hours prior to exercise. Montelukast can be administered as monotherapy or added to LABA-ICS therapy. It is suitable for adults, children, and infants over 1 year of age, preferably taken at night to prevent symptoms in the early morning. Possible side effects include respiratory tract infections, abdominal pain, diarrhea, and neuropsychiatric disorders. Montelukast is considered safe for use during pregnancy and breastfeeding. Physicians should provide comprehensive education for patients regarding medication compliance and the potential risks of side effects. Regular daily use of montelukast is beneficial in preventing acute exacerbations in asthma patients.
Development of an EKA application to help tuberculosis patients improve medication adherence and self efficacy Fuadiati, Lie Liana; Sukartini, Tintin; Makhfudli, Makhfudli; Dewi, Yulis Setiya; Rosyid, Alfian Nur; Qona’ah, Arina
International Journal of Public Health Science (IJPHS) Vol 13, No 1: March 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i1.23309

Abstract

Tuberculosis treatment is carried out daily for a long time, causing boredom with taking medication and reducing medication adherence. It results in drug resistance and more prolonged treatment. In response to the situation, this study developed an android-based application called the education, calendar, and medication alarm (EKA) app to improve medication adherence and self-efficacy of tuberculosis patients. Research and development with four steps: evaluation of health education, medication adherence, and self-efficacy; application development; feasibility test; and application socialization. The sample in this study was 38 respondents. This study also uses morisky medication adherence scale (MMAS-8), self-efficacy, and system usability scale (SUS) questionnaires and evaluation sheets to collect the data. Data analysis was done descriptively. The outcomes of the application feasibility test showed that the EKA application received an acceptable value of 81.5 based on acceptance, B value (81.5) based on value scale, an excellent value (81.5) based on adjective rating, and good score (81.5) based on percentile. Socialization on the use of the application goes well, and the patient gets a good understanding and can use the EKA application easily. It proves that the android-based EKA application tested using the SUS questionnaire can be used as a medium for health education and supports medication adherence and self-efficacy.
Co-Authors Abdul Khairul Rizki Purba Mustofa Indwiani Astuti Anastasya Annisa Karlina Ardi, Bangun Mukti Arief Bakhtiar Arifandi, Yoga Akbar Arina Dery Puspitasari Asmahan Farah Adiba Astanti, Erika Bakhtiar, Arief Bambang Subakti Zulkarnain Brigitta Dhyah Kunthi Wardhani Brigitta Dhyah Kunthi Wardhani BUDI UTOMO D. Puspitasari, Arina Dava Aulia Dhieo Kurniawan Diah Indriani Duta, Garinda Alma Effendi, Wiwin Is Eunice Marlene Sicilia Kundiman Eunice Marlene Sicilia Kundiman Eunice Marlene Sicilia Kundiman Farah Meutia Fatimatuz Zahra Oviary Satryo Fatimatuz Zahra Oviary Satryo Fatimatuz Zahra Oviary Satryo Fatimatuz Zahra Oviary Satryo Fauzul Meiliani Fauzul Meiliani Fauzul Meiliani Fauzul Meiliani Hafidz Alfarobi Handira Nadhifatul Aini Hasanudin Hasanudin Herley Windo Setiawan I Made Dwi Yudiartana Putra Susila Idwar, Fadiah Dini Putri Ika Nindya Kadariswantiningsih Indiastuti, Danti Nur Isnin Anang Marhana Izzatul Fitriyah Kusuma, Edward Putra Lie Liana Fuadiati Lily Aina Lily Aina Lily Aina Lily Aina M. Yamin Maftuchah Maftuchah Makhfudli Makhfudli Maranatha, Daniel Mareta Rindang Andarsari Maulana Antiyan Empitu Melinda Putri Amelia Rachman Melinda Putri Amelia Rachman Melinda Putri Amelia Rachman Melinda Putri Amelia Rachman Mochamad Rafi Pratama Hariyanto Putra MOCHAMMAD THAHA Muhammad Amin Muhammad Amin Muhammad Rivai Mutiara Rizki Haryati Nafikhah, Wardah Zuhan Nanda Ardianto Nanda Ardianto Nanda Ardianto Nanda Ardianto Natalia Christin Tiara Revita Naura Alya Hirmadiani Nur Rachmawati Maulida Nursalam Nursalam Pharmasinta Putri Hapsari Pirlina Umiastuti Prastuti Asta Wulaningrum Qona’ah, Arina Rahma, Rachel Sabila Resti Yudhawati Reyna Cesariyani Rahmadianti Rusuldi Riyanarto Sarno Sanchia Callista Raihanah Wiryawan Sarah Mahmudatun Nabila Sensusiati, Anggraini Dwi Sharifa Audi Salsabila Shintami Chusnul Hidayati Soenarnatalina Melaniani Suryantoro, Satriyo Dwi Tafana Fadhillah Laili Tamara nUR Budiarti Tamara Nur Budiarti Tamara Nur Budiarti Temenggung, Bintang Tintin Sukartini Sukartini, Tintin Sukartini Toetik Aryani Vatine Adila Wahyunitisari, Manik Retno Wedhana, Hilmy Indra Wironegoro, Rio Wiwin Retnowati Yasmin Karimah Ikhsan Yulis Setiya Dewi Yuliza Yuliza Yusuke Suzuki Zedny Norachuriya