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All Journal EKSAKTA: Journal of Sciences and Data Analysis Jurnal Ilmiah Manuntung Dinamisia: Jurnal Pengabdian Kepada Masyarakat JURNAL KESEHATAN PERINTIS Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmagazine Journal of Pharmaceutical and Health Research Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Journal of Experimental and Clinical Pharmacy (JECP) Jurnal IPTEK Bagi Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan International Journal Mathla'ul Anwar of Halal Issues Jurnal Abdi Masyarakat Kita Sciences of Pharmacy Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Journal of Global Pharma Technology Jurnal Pengabdian Pada Masyarakat Jurnal Ilmiah Kesehatan Delima Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Stiani, Sofi Nurmay
STIKes Salsabila Serang
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UJI AKTIVITAS ANTIDIARE EKSTRAK ETANOL 70% KULIT BUAH JENGKOL (Archidendron pauciflorum (Benth.) I.C.Nielsen) TERHADAP MENCIT JANTAN YANG DIINDUKSI OLEUM RICINI Mohammad Rizal; Yusransyah Yusransyah; Sofi Nurmay Stiani
Jurnal Ilmiah Manuntung Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i2.57

Abstract

Plants that can be used as a medicinal plant one of which is Jengkol (Archidendron pauciflorum (Benth.) IC.Nielsen.). Seeds, bark and leaves jengkol contains saponins, flavonoids and tannins. The purpose of this study was to test the antidiarrheal activity of 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) ICNielsen) to male mice that includes a solution of distilled water as a control, loperamide as a comparison, the ethanol extract of the fruit peel jengkol as test material, and oleum ricini as inductors. Research method used laboratory experiments. Data were analyzed by ANOVA (Analysis of Variance) and continued with different test average – average Duncan using SPSS (Statistical Product and Service Solutions). The results of that study 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) IC Nielsen) provide nonspecific antidiarrheal activity. The content of the metabolites were present in 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) IC Nielsen) which provides non-specific activity as antidiarrheal are tannins, flavonoids and steroids. Ethanol Extract Fruit Leather Jengkol 1.2 mg / g has a stronger effect in reducing diarrhea and provide optimum activity as nonspecific antidiarrheal.
DAUN KECOMBRANG (Etlingera elatior) SEBAGAI ANTIHPERGLIKEMI PADA PENDERITA DIABETES MELLITUS Lutfiyah, Fifih; Sulaeman, Agus; Stiani, Sofi Nurmay
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 24 No. 1 (2025): Januari 2025
Publisher : Faculty of Medicine Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/ibnusina.v24i1.701

Abstract

Diabetes mellitus adalah penyakit metabolik yang berlangsung lama yang menjadi masalah kesehatan di seluruh dunia. Etlingera elatior, juga dikenal sebagai kecombrang, telah digunakan sejak lama dalam pengobatan tradisional. Itu menunjukkan potensi sebagai agen antihiperglikemik. Dengan menganalisis literatur yang luas, penelitian ini mengeksplorasi potensi. Etlingera elatior sebagai antihiperglikemik pada penderita diabetes mellitus. Dalam uji in vitro dan in vivo, ekstrak Etlingera elatior menunjukkan sifat antihiperglikemik yang signifikan. Mekanisme kerjanya termasuk mencegah enzim α-glukosidase dan α-amilase, meningkatkan sensitivitas insulin, dan aktivitas antioksidan yang melindungi sel pankreas dan organ lain dari stres oksidatif. Efek antidiabetes tanaman ini disebabkan oleh senyawa bioaktif seperti flavonoid dan fenolik. Etlingera elatior memiliki kemampuan untuk mencegah komplikasi diabetes seperti nefropati dan katarak selain menurunkan kadar glukosa darah. Sebagian besar penelitian dilakukan pada hewan model atau in vitro, meskipun hasilnya sangat menjanjikan. Akibatnya, penelitian tambahan diperlukan untuk mengetahui apakah Etlingera elatior aman dan efektif untuk digunakan pada manusia, serta untuk menentukan dosis terbaik dan jenis sediaan yang paling efektif untuk mengobati diabetes mellitus.
EVALUASI IMPLEMENTASI PELAYANAN KEFARMASIAN PADA PUSKESMAS DI KABUPATEN PANDEGLANG TAHUN 2024 Yusransyah, Yusransyah; Stiani, Sofi Nurmay; Nasiti, Febriane Dwi; Kelutur, Faruk Jayanto; Udin, Baha
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i1.2389

Abstract

Pharmaceutical services are considered by some observers to be below standard. Both pharmacists and pharmaceutical technicians as health technicians are required to improve their skills, knowledge and behavior in order to provide quality direct services to patients. The purpose of this study was to determine the implementation of pharmaceutical services at Health Centers in Pandeglang Regency in 2023. This study is an observational study with a case study design. The method used is descriptive using checklist sheets and open statements. Based on the results of this study, there are significant differences in the aspects of facilities and infrastructure and clinical pharmacy services and there are differences but not significant in the aspects of managing pharmaceutical preparations and disposable medical materials. The conclusion of this study is that pharmaceutical services at Health Centers in Pandeglang Regency are in accordance with Permenkes No. 74 of 2016 by obtaining a percentage value of 79%, entering the GOOD category.
Determination of Total Flavonoid Content and Characterization of Nanoparticles of Kecombrang Leaf Extract (Etlingera elatior (Jack) R.M.Sm.) Hayati, Farida; Sofi Nurmay Stiani; Renditya Ismiyati
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 6, ISSUE 1, April 2025
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/EKSAKTA.vol6.iss1.art4

Abstract

Kecombrang (Etlingera elatior (Jack) R.M.Sm.) is one of Indonesia's potential plants that contain such bioactive compounds as polyphenols, alkaloids, flavonoids, steroids, saponins, and essential oils. This study aims to determine the total flavonoid content of kecombrang leaf extract. It also defines the characteristics of the nanoparticles of kecombrang leaf extract. Kecombrang leaves were extracted through maceration. The determination of the total flavonoid content by spectrophotometry used quercetin as a comparison. The synthesis of nanoparticles used ionic gelation with 0.1% sodium alginate and 0.01% calcium chloride crosslinkers. The characteristic parameters of the nanoparticles of kecombrang leaf extract included the visual, transmittance, adsorption efficiency, particle size distribution, polydispersity index, and zeta potential. The yield value was 46.55%. The total flavonoid content was 88.11 mgQE/g with a regression standard curve Y = 0.1022x + 0.0745 and correlation coefficient (r) = 0.9922. The nanoparticle solution provided a clear visual with a particle size and PI of 108.2 nm and 0.311, a transmittance and adsorption efficiency of 94.76% and 93.76%, and a zeta potential of -36 mV. The total flavonoid content was 88.11 mgQE/g. The nanoparticle solution of kecombrang leaf extract has the characteristics that qualify as a nanoparticle preparation.
Peran Apoteker dalam Kepatuhan Penggunaan Tablet Tambah Darah untuk Pencegahan Stunting pada Siswi Pelita Cibitung Yusransyah, Yusransyah; Alfarizqi, Asep Salman; Sudarto, Teguh; Kholifah, Eva; Stiani, Sofi Nurmay; Udin, Baha
Jurnal IPTEK Bagi Masyarakat Vol 4 No 3 (2025)
Publisher : Ali Institute of Research and Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55537/j-ibm.v4i3.1114

Abstract

Anemia in adolescent girls is a significant health issue in Indonesia, with high prevalence and long-term impacts on reproductive health, as well as an increased risk of stunting in their offspring. The Iron Supplementation (TTD) program has been initiated by the government as a stunting prevention effort, yet adherence to TTD consumption among adolescent girls remains low. The role of pharmacists as educators and facilitators in public health programs is crucial in improving TTD consumption adherence. This community service aims to improve adherence to TTD consumption as a stunting prevention measure among female vocational school students through the Anti-Stunting Movement Program at Pelita Cibitung Vocational School in 2024. Activities conducted include interactive education on stunting, anemia, and the importance of TTD consumption, as well as monitoring and evaluating TTD consumption adherence. Evaluation was performed using the Medication Adherence Report Scale (MARS) questionnaire. The evaluation results showed an increase in TTD consumption adherence after education and monitoring through WhatsApp Group. This demonstrates that the active involvement of pharmacists in education and monitoring can improve adherence to TTD consumption in adolescent girls.
Effectiveness of TB-Reminder Application in Improving Medication Adherence and Quality of Life of Lung Tuberculosis Patients in Indonesia Yusransyah, Yusransyah; Stiani, Sofi Nurmay; Chairani, Farahdina; Adini, Syilvi; Subchan, Mohamad; Ferdiyansyah, Ferdiyansyah; Putri, Nabila Septiani; Pratiwi, Rossi; Udin, Baha
Sciences of Pharmacy Volume 4 Issue 3
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0403358

Abstract

Poor adherence to anti-tuberculosis (TB) treatment continues to hinder therapeutic success and patient quality of life. This study aimed to evaluate the effectiveness of the TB-R mobile application in improving medication adherence and quality of life among pulmonary TB patients at Pandeglang Regional Hospital. Eighty-six patients were randomized into intervention (n = 43) and control (n = 43) groups. Adherence and quality of life were measured using the Medication Adherence Rating Scale (MARS) and EQ-5D-5L, respectively. After one month, the intervention group demonstrated significantly higher adherence (97.7% vs. 79.0%, p < 0.001) and improvement in mean MARS scores (24.7 vs. 22.7, p < 0.001). Although quality of life gains were not statistically significant overall, notable improvements were observed in anxiety/depression and self-care domains. Demographic factors influenced outcomes: patients aged 29–39 and those living with others showed better adherence, while patients aged 40–50 experienced greater quality of life gains. Women aged 51–60 living alone had decreased adherence despite quality of life improvements. These results suggest that mHealth tools like TB-R can enhance adherence, especially when supported by favorable social and demographic conditions. Tailored digital interventions may optimize treatment outcomes in TB care. Future mHealth app development should consider these social and demographic factors to maximize effectiveness and user engagement.
TINGKAT PENGETAHUAN, PERSEPSI, DAN SIKAP MASYARAKAT MUSLIM TERHADAP KEHALALAN OBAT DI DESA SUKARENDAH, SUKARAJA, DAN PADASUKA KABUPATEN LEBAK TAHUN 2024 Noviyanto, Fajrin; Apriliani, Ade; Stiani, Sofi Nurmay; Shobah, Afifah Nur; Halimatusyadiah, Leni
International Journal Mathla’ul Anwar of Halal Issues Vol. 4 No. 2 (2024)
Publisher : Universitas Mathla’ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/ijma.202442.116

Abstract

Halal drugs became a very important issue discussed given th at th ere a re st ill ma ny drugs found that are suspected of containing illegal substances and have not been identified as halal. The aim of this research is to determine the level of knowledge, perception, and public attitude about the validity of drugs and to identify the factors that influence the knowledge, perceived, and attitude of the public about the legitimacy of drugs in the villages of Sukarendah, Sukaraja, and Padasuka. This research uses a descriptive approach model (non eksperimental). On sampling in the population of the village community Sukarendah, Sukaraja, and Padasuka used propability samplings, and collected data through questionnaires. According to the results of the research showed that the level of knowledge about the validity of drugs in the villages of Sukarendah, Sukaraja, and Padasuk very well has a score of 82.86%, the perception of the village people of Skarendha, Sukarasu, and Padasuk to the legitimacy of drugs very good score of 74.29%, the attitude of the people of the towns of Sskarendh, sukaraja and Padassuk very good to the validation of drugs score of 94.3%. Overall, it can be said that the knowledge, understanding, and perception levels of the community of villages are very good.
Pharmacoeconomic Analysis of Drugs Used in Chronic Outpatients at Berkah Pandeglang Regional Hospital Yusransyah, Yusransyah; Nurhikmah, Ihda; Maharani, Zahra Citra; Stiani, Sofi Nurmay; Shobah, Afifah Nur; Udin, Baha
Sciences of Pharmacy Volume 4 Issue 3
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hypertension and type 2 diabetes mellitus (T2DM) are chronic conditions requiring long-term pharmacotherapy, placing significant financial pressure on patients and healthcare systems. Drug selection should prioritize both clinical efficacy and cost-efficiency, particularly in resource-limited settings. This study conducted a pharmacoeconomic evaluation of commonly used therapies at RSUD Berkah Pandeglang using a retrospective, non-experimental design. Data were collected from 2023 outpatient records and analyzed from the hospital’s perspective. Cost-effectiveness was assessed using the Average Cost-Effectiveness Ratio (ACER). For hypertension, amlodipine (n=20) had a lower ACER (Rp 283,913) than candesartan (n=15; Rp 883,000), indicating higher cost-effectiveness. In T2DM patients, metformin (n=25) was more cost-effective (ACER: Rp 317,746.75) than glimepiride (n=25; ACER: Rp 607,148.84). These findings support prioritizing amlodipine and metformin as first-line treatments in similar public healthcare settings to improve therapeutic outcomes while managing costs.
Analisis biaya penggunaan analgetik sebagai terapi antinyeri pada pasien pasca bedah apendisitis di RSUD Aulia Pandeglang Yusransyah, Yusransyah; Stiani, Sofi Nurmay; Cahya, Wulan; Udin, Baha
Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Vol. 9 No. 1 (2025): Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)
Publisher : Sekolah Tinggi Ilmu Kesehatan Holistik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51873/jhhs.v9i1.349

Abstract

Latar belakang: Penggunaan analgetik sebagai terapi antinyeri pada pasien pasca bedah apendisitis di rumah sakit memiliki peran yang signifikan dalam mendukung proses pemulihan pasien. Namun, seiring meningkatnya biaya perawatan kesehatan, penting bagi fasilitas kesehatan untuk mengoptimalkan penggunaan analgetik agar tetap efektif namun juga ekonomis. Minimisasi biaya penggunaan analgetik tanpa mengorbankan efektivitas terapi menjadi tantangan utama dalam memastikan pasien mendapatkan perawatan yang optimal. Tujuan penelitian: Penelitian ini bertujuan untuk menentukan penggunaan obat analgesik dengan biaya paling rendah pada pasien pasca operasi apendisitis di RSUD Aulia Pandeglang. Metode penelitian: Metode penelitian yang digunakan adalah pengambilan data secara retrospektif dengan menggunakan data sekunder berupa rekam medis dan rincian biaya pengobatan pasien pasca operasi apendisitis yang tersedia di rumah sakit. Hasil: Hasil penelitian menunjukkan bahwa rata-rata biaya total untuk analgetik Tramadol injeksi dengan lama pengobatan 3 hari adalah Rp. 2.893.400,00/pasien, Dexketoprofen oral dengan lama pengobatan 3 hari adalah Rp. 11.051.400,00/pasien, Ketorolac injeksi dengan lama pengobatan 9 hari adalah Rp. 27.067.531,00/pasien, Paracetamol oral dengan lama pengobatan 7 hari adalah Rp. 13.212.000,00/pasien, Asam Mefenamat oral dengan lama pengobatan 10 hari adalah Rp. 2.929.000,00/pasien, Natrium Diklofenak oral dengan lama pengobatan 3 hari adalah Rp. 10.929.052,00/pasien, Ibuprofen oral dengan lama pengobatan 5 hari adalah Rp. 3.957.000,00/pasien, dan Ketoprofen injeksi dengan lama pengobatan 6 hari adalah Rp. 13.239.000,00/pasien. Simpulan: Berdasarkan data tersebut, analgetik injeksi Tramadol memiliki biaya total rata-rata paling rendah dibandingkan dengan analgetik lainnya
Edukasi Efek Samping Obat dan Resiko Penggunaan Obat yang Salah di Pantiasuhan Hasanudin Pandeglang Stiani, Sofi Nurmay; Yusransyah, Yusransyah; Ernawati, Eneng Elda; Udin, Baha; US, Sumarlin; Fahlevy, Muhamad Ichsan; Junaedi, Candra; Noviyanto, Fajrin
Jurnal IPTEK Bagi Masyarakat Vol 5 No 1 (2025)
Publisher : Ali Institute of Research and Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55537/j-ibm.v5i1.1117

Abstract

Improper use of drugs can cause adverse side effects, especially among people with limited access to information such as people living in orphanages. This community service activity aims to increase the knowledge of residents of the Hasanudin Pandeglang Orphanage regarding the side effects of drugs and the risks of incorrect drug use through educational activities. The method used is health education accompanied by a question and answer discussion and pretest and posttest evaluation using a knowledge questionnaire. The questionnaire was designed to measure participants' understanding of the material presented before and after education. The number of participants in this activity was 57 participants. The evaluation results showed a significant increase in participants' knowledge scores after the education. This proves that this educational activity is effective in increasing awareness and understanding of the safe use of drugs. This activity is expected to be a model for similar health education in other orphanages to prevent irrational drug use.
Co-Authors Achmad Fudholi Ade Anwar Ade Apriliani Adini, Syilvi Afifah Nur Shobah Agus Sulaeman Alfarizqi, Asep Salman Anwar, Ade Apriliani, Ade Audy Nursifa'atun Aufalya Wibirezkina Aulia, Ayu Cahya, Wulan Chairani, Farahdina Deya Adiby Nabillah Elfrida Ratnawati endah, endah Endi Muchyar Eneng Elda Ernawati Ernawati, Eneng Elda Fahlevy, Muhamad Ichsan Fajrin Noviyanto Fajrin Noviyanto, Fajrin Ferdiyansyah, Ferdiyansyah Fifih Lutfiyah Ghina Annufus Harpan, Andri Hayati, Farida Herawati, Fera Ismiyati, Renditya Junaedi, Candra Kelutur, Faruk Jayanto Kholifah, Eva Kuncoro, Banu Leni Halimatusyadiah Lidiah, Mae Lutfiyah, Fifih Maharani, Zahra Citra Masfuah, Imas Megawati, Sefi Mohammad Rizal Mohammad Rizal, Mohammad Nabillah, Deya Adiby Nasiti, Febriane Dwi Neneng Nasliah Nita Rusdiana S.Farm., M.Sc, Apt Nurani, Agnes Wieanita Nurhikmah, Ihda Nurul Fitri, Nabila Oktaviana Hadi, Agriyaningsih Pratiwi, Linda Rani Pratiwi, Rossi Putri, Nabila Septiani Rahmawida Putri Renditya Ismiyati Renditya Ismiyati Rini Rumantir Rizkiana, Muhammad Dinta Rustiyani, Risa Sabilla, Aliffia Nur Salsabillah, Audy Nursifa'atun Satibi . Seira, Trisya Septina Sumantri, Aulia Shobah, Afifah Nur Siska Purnama Sari Siti Lailatu Zahroh Siti Marina Subchan, Mohamad Suci Nurainun Sudarto, Teguh Sumarlin US Sylvianti Maharani Udin, Baha US, Sumarlin Wibirezkina, Aufalya Yusransyah Yusransyah Yusransyah Yusransyah Yusransyah, Yusransyah