Article Per Year (5 Year)
p-Index From 2021 - 2026
6.364
P-Index
This Author published in this journals
All Journal EKSAKTA: Journal of Sciences and Data Analysis Dinamisia: Jurnal Pengabdian Kepada Masyarakat JURNAL KESEHATAN PERINTIS Jurnal Ilmu Kefarmasian Indonesia Pharmacoscript Jurnal Farmamedika (Pharmamedica Journal) Jurnal Farmagazine Journal of Pharmaceutical and Health Research Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Journal of Experimental and Clinical Pharmacy (JECP) Jurnal IPTEK Bagi Masyarakat Jurnal Pengabdian Masyarakat Aufa (JPMA) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan International Journal Mathla'ul Anwar of Halal Issues Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Abdi Masyarakat Kita Sciences of Pharmacy Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Journal of Global Pharma Technology Jurnal Pengabdian Pada Masyarakat Jurnal Ilmiah Kesehatan Delima Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Stiani, Sofi Nurmay
Sekolah Tinggi Ilmu Kesehatan Salsabila Serang
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

Published : 54 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 54 Documents
Search

 2   3   4   5   6 
UJI AKTIVITAS ANTIDIARE EKSTRAK ETANOL 70% KULIT BUAH JENGKOL (Archidendron pauciflorum (Benth.) I.C.Nielsen) TERHADAP MENCIT JANTAN YANG DIINDUKSI OLEUM RICINI Mohammad Rizal; Yusransyah Yusransyah; Sofi Nurmay Stiani
Jurnal Ilmiah Manuntung Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i2.57

Abstract

Plants that can be used as a medicinal plant one of which is Jengkol (Archidendron pauciflorum (Benth.) IC.Nielsen.). Seeds, bark and leaves jengkol contains saponins, flavonoids and tannins. The purpose of this study was to test the antidiarrheal activity of 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) ICNielsen) to male mice that includes a solution of distilled water as a control, loperamide as a comparison, the ethanol extract of the fruit peel jengkol as test material, and oleum ricini as inductors. Research method used laboratory experiments. Data were analyzed by ANOVA (Analysis of Variance) and continued with different test average – average Duncan using SPSS (Statistical Product and Service Solutions). The results of that study 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) IC Nielsen) provide nonspecific antidiarrheal activity. The content of the metabolites were present in 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) IC Nielsen) which provides non-specific activity as antidiarrheal are tannins, flavonoids and steroids. Ethanol Extract Fruit Leather Jengkol 1.2 mg / g has a stronger effect in reducing diarrhea and provide optimum activity as nonspecific antidiarrheal.
DAUN KECOMBRANG (Etlingera elatior) SEBAGAI ANTIHPERGLIKEMI PADA PENDERITA DIABETES MELLITUS Lutfiyah, Fifih; Sulaeman, Agus; Stiani, Sofi Nurmay
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 24 No. 1 (2025): Januari 2025
Publisher : Faculty of Medicine Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/ibnusina.v24i1.701

Abstract

Diabetes mellitus adalah penyakit metabolik yang berlangsung lama yang menjadi masalah kesehatan di seluruh dunia. Etlingera elatior, juga dikenal sebagai kecombrang, telah digunakan sejak lama dalam pengobatan tradisional. Itu menunjukkan potensi sebagai agen antihiperglikemik. Dengan menganalisis literatur yang luas, penelitian ini mengeksplorasi potensi. Etlingera elatior sebagai antihiperglikemik pada penderita diabetes mellitus. Dalam uji in vitro dan in vivo, ekstrak Etlingera elatior menunjukkan sifat antihiperglikemik yang signifikan. Mekanisme kerjanya termasuk mencegah enzim α-glukosidase dan α-amilase, meningkatkan sensitivitas insulin, dan aktivitas antioksidan yang melindungi sel pankreas dan organ lain dari stres oksidatif. Efek antidiabetes tanaman ini disebabkan oleh senyawa bioaktif seperti flavonoid dan fenolik. Etlingera elatior memiliki kemampuan untuk mencegah komplikasi diabetes seperti nefropati dan katarak selain menurunkan kadar glukosa darah. Sebagian besar penelitian dilakukan pada hewan model atau in vitro, meskipun hasilnya sangat menjanjikan. Akibatnya, penelitian tambahan diperlukan untuk mengetahui apakah Etlingera elatior aman dan efektif untuk digunakan pada manusia, serta untuk menentukan dosis terbaik dan jenis sediaan yang paling efektif untuk mengobati diabetes mellitus.
EVALUASI IMPLEMENTASI PELAYANAN KEFARMASIAN PADA PUSKESMAS DI KABUPATEN PANDEGLANG TAHUN 2024 Yusransyah, Yusransyah; Stiani, Sofi Nurmay; Nasiti, Febriane Dwi; Kelutur, Faruk Jayanto; Udin, Baha
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i1.2389

Abstract

Pharmaceutical services are considered by some observers to be below standard. Both pharmacists and pharmaceutical technicians as health technicians are required to improve their skills, knowledge and behavior in order to provide quality direct services to patients. The purpose of this study was to determine the implementation of pharmaceutical services at Health Centers in Pandeglang Regency in 2023. This study is an observational study with a case study design. The method used is descriptive using checklist sheets and open statements. Based on the results of this study, there are significant differences in the aspects of facilities and infrastructure and clinical pharmacy services and there are differences but not significant in the aspects of managing pharmaceutical preparations and disposable medical materials. The conclusion of this study is that pharmaceutical services at Health Centers in Pandeglang Regency are in accordance with Permenkes No. 74 of 2016 by obtaining a percentage value of 79%, entering the GOOD category.
Determination of Total Flavonoid Content and Characterization of Nanoparticles of Kecombrang Leaf Extract (Etlingera elatior (Jack) R.M.Sm.) Hayati, Farida; Sofi Nurmay Stiani; Renditya Ismiyati
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 6, ISSUE 1, April 2025
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/EKSAKTA.vol6.iss1.art4

Abstract

Kecombrang (Etlingera elatior (Jack) R.M.Sm.) is one of Indonesia's potential plants that contain such bioactive compounds as polyphenols, alkaloids, flavonoids, steroids, saponins, and essential oils. This study aims to determine the total flavonoid content of kecombrang leaf extract. It also defines the characteristics of the nanoparticles of kecombrang leaf extract. Kecombrang leaves were extracted through maceration. The determination of the total flavonoid content by spectrophotometry used quercetin as a comparison. The synthesis of nanoparticles used ionic gelation with 0.1% sodium alginate and 0.01% calcium chloride crosslinkers. The characteristic parameters of the nanoparticles of kecombrang leaf extract included the visual, transmittance, adsorption efficiency, particle size distribution, polydispersity index, and zeta potential. The yield value was 46.55%. The total flavonoid content was 88.11 mgQE/g with a regression standard curve Y = 0.1022x + 0.0745 and correlation coefficient (r) = 0.9922. The nanoparticle solution provided a clear visual with a particle size and PI of 108.2 nm and 0.311, a transmittance and adsorption efficiency of 94.76% and 93.76%, and a zeta potential of -36 mV. The total flavonoid content was 88.11 mgQE/g. The nanoparticle solution of kecombrang leaf extract has the characteristics that qualify as a nanoparticle preparation.
TINGKAT PENGETAHUAN, PERSEPSI, DAN SIKAP MASYARAKAT MUSLIM TERHADAP KEHALALAN OBAT DI DESA SUKARENDAH, SUKARAJA, DAN PADASUKA KABUPATEN LEBAK TAHUN 2024 Noviyanto, Fajrin; Apriliani, Ade; Stiani, Sofi Nurmay; Shobah, Afifah Nur; Halimatusyadiah, Leni
International Journal Mathla’ul Anwar of Halal Issues Vol. 4 No. 2 (2024)
Publisher : Universitas Mathla’ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/ijma.202442.116

Abstract

Halal drugs became a very important issue discussed given th at th ere a re st ill ma ny drugs found that are suspected of containing illegal substances and have not been identified as halal. The aim of this research is to determine the level of knowledge, perception, and public attitude about the validity of drugs and to identify the factors that influence the knowledge, perceived, and attitude of the public about the legitimacy of drugs in the villages of Sukarendah, Sukaraja, and Padasuka. This research uses a descriptive approach model (non eksperimental). On sampling in the population of the village community Sukarendah, Sukaraja, and Padasuka used propability samplings, and collected data through questionnaires. According to the results of the research showed that the level of knowledge about the validity of drugs in the villages of Sukarendah, Sukaraja, and Padasuk very well has a score of 82.86%, the perception of the village people of Skarendha, Sukarasu, and Padasuk to the legitimacy of drugs very good score of 74.29%, the attitude of the people of the towns of Sskarendh, sukaraja and Padassuk very good to the validation of drugs score of 94.3%. Overall, it can be said that the knowledge, understanding, and perception levels of the community of villages are very good.
Pharmacoeconomic Analysis of Drugs Used in Chronic Outpatients at Berkah Pandeglang Regional Hospital Yusransyah, Yusransyah; Nurhikmah, Ihda; Maharani, Zahra Citra; Stiani, Sofi Nurmay; Shobah, Afifah Nur; Udin, Baha
Sciences of Pharmacy Volume 4 Issue 3
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0403343

Abstract

Hypertension and type 2 diabetes mellitus (T2DM) are chronic conditions requiring long-term pharmacotherapy, placing significant financial pressure on patients and healthcare systems. Drug selection should prioritize both clinical efficacy and cost-efficiency, particularly in resource-limited settings. This study conducted a pharmacoeconomic evaluation of commonly used therapies at RSUD Berkah Pandeglang using a retrospective, non-experimental design. Data were collected from 2023 outpatient records and analyzed from the hospital’s perspective. Cost-effectiveness was assessed using the Average Cost-Effectiveness Ratio (ACER). For hypertension, amlodipine (n = 20) had a lower ACER (Rp 283,913) than candesartan (n = 15; Rp 883,000), indicating higher cost-effectiveness. In T2DM patients, metformin (n = 25) was more cost-effective (ACER: Rp 317,746.75) than glimepiride (n = 25; ACER: Rp 607,148.84). These findings support prioritizing amlodipine and metformin as first-line treatments in similar public healthcare settings to improve therapeutic outcomes while managing costs.
Analisis biaya penggunaan analgetik sebagai terapi antinyeri pada pasien pasca bedah apendisitis di RSUD Aulia Pandeglang Yusransyah, Yusransyah; Stiani, Sofi Nurmay; Cahya, Wulan; Udin, Baha
Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Vol. 9 No. 1 (2025): Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)
Publisher : Sekolah Tinggi Ilmu Kesehatan Holistik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51873/jhhs.v9i1.349

Abstract

Latar belakang: Penggunaan analgetik sebagai terapi antinyeri pada pasien pasca bedah apendisitis di rumah sakit memiliki peran yang signifikan dalam mendukung proses pemulihan pasien. Namun, seiring meningkatnya biaya perawatan kesehatan, penting bagi fasilitas kesehatan untuk mengoptimalkan penggunaan analgetik agar tetap efektif namun juga ekonomis. Minimisasi biaya penggunaan analgetik tanpa mengorbankan efektivitas terapi menjadi tantangan utama dalam memastikan pasien mendapatkan perawatan yang optimal. Tujuan penelitian: Penelitian ini bertujuan untuk menentukan penggunaan obat analgesik dengan biaya paling rendah pada pasien pasca operasi apendisitis di RSUD Aulia Pandeglang. Metode penelitian: Metode penelitian yang digunakan adalah pengambilan data secara retrospektif dengan menggunakan data sekunder berupa rekam medis dan rincian biaya pengobatan pasien pasca operasi apendisitis yang tersedia di rumah sakit. Hasil: Hasil penelitian menunjukkan bahwa rata-rata biaya total untuk analgetik Tramadol injeksi dengan lama pengobatan 3 hari adalah Rp. 2.893.400,00/pasien, Dexketoprofen oral dengan lama pengobatan 3 hari adalah Rp. 11.051.400,00/pasien, Ketorolac injeksi dengan lama pengobatan 9 hari adalah Rp. 27.067.531,00/pasien, Paracetamol oral dengan lama pengobatan 7 hari adalah Rp. 13.212.000,00/pasien, Asam Mefenamat oral dengan lama pengobatan 10 hari adalah Rp. 2.929.000,00/pasien, Natrium Diklofenak oral dengan lama pengobatan 3 hari adalah Rp. 10.929.052,00/pasien, Ibuprofen oral dengan lama pengobatan 5 hari adalah Rp. 3.957.000,00/pasien, dan Ketoprofen injeksi dengan lama pengobatan 6 hari adalah Rp. 13.239.000,00/pasien. Simpulan: Berdasarkan data tersebut, analgetik injeksi Tramadol memiliki biaya total rata-rata paling rendah dibandingkan dengan analgetik lainnya
Mercury Identification Training and Safe Cosmetics Education for Babunnajah Vocational School Students.: Pelatihan Identifikasi Merkuri dan Edukasi Kosmetik Aman bagi Siswa SMK Babunnajah Stiani, Sofi Nurmay; Oktaviana Hadi, Agriyaningsih; Yusransyah, Yusransyah; Subchan, Mohamad; Nurul Fitri, Nabila; Septina Sumantri, Aulia; Udin, Baha
Dinamisia : Jurnal Pengabdian Kepada Masyarakat Vol. 9 No. 4 (2025): Dinamisia: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Lancang Kuning

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31849/qtrzgt54

Abstract

The use of unsafe cosmetics among adolescents, particularly those containing mercury, remains a significant public health concern. This community service program aimed to enhance students’ knowledge at SMK Babunnajah through training in mercury identification and education on the safe use of cosmetics. The activity employed interactive lectures, group discussions, and hands-on mercury testing using simple reagent kits. An evaluation was conducted using pre-test and post-test questionnaires with 40 students. The results showed a substantial improvement in knowledge levels, with 70% of participants categorised as having high knowledge before the training, increasing to 100% afterwards. All knowledge indicators showed improvement, particularly in understanding product legality and the risks of mercury exposure. This training proved effective in fostering critical awareness and selective behaviour regarding cosmetic use. The program is recommended for replication in other vocational schools as a preventive measure against the use of illegal and harmful cosmetic products.
COST-EFFECTIVENESS DEXKETOPROFEN VS KETOROLAC IN CAESAREAN PATIENTS AT 'X' HOSPITAL, PANDEGLANG Yusransyah, Yusransyah; Sofi Nurmay, Stiani; Farahdina, Chairani; Latifah Nur, Rizki; Baha, Udin
Pharmacoscript Vol. 8 No. 2 (2025): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v8i2.2150

Abstract

Post-cesarean section pain must be treated promptly and appropriately to prevent chronic conditions. Dexketoprofen and Ketorolac are non-narcotic analgesics commonly used to manage such pain. This study aimed to analyse the cost-effectiveness of dexketoprofen and ketorolac in patients undergoing cesarean sections at Mother and Child Hospital "X" in Pandeglang. The study used a cross-sectional design with cost-effectiveness analysis, specifically the Average Cost-Effectiveness Ratio (ACER). Pain intensity was measured one hour after surgery using the Faces Pain Rating Scale and Visual Analog Scale (VAS). Inclusion criteria were patients who underwent cesarean section and received non-narcotic analgesics. A total of 90 patients participated: 39 in the dexketoprofen group and 51 in the ketorolac group. Data were analyzed using ACER and the Mann-Whitney test. The ACER, based on the Faces Pain Rating Scale, showed a cost of IDR 1,142 for the dexketoprofen group and IDR 958.03 for the ketorolac group. Using the VAS, the cost was IDR 1,110 for dexketoprofen and IDR 657.45 for ketorolac. Statistical results showed a p-value < 0.05 for both pain measurement tools, indicating a significant difference in effectiveness between the two therapies. Based on both instruments, ketorolac was more cost-effective than dexketoprofen in managing post-cesarean section pain. This finding suggests that ketorolac may be a preferable option in clinical settings where cost and effectiveness are key considerations for post-operative analgesia in cesarean section patients.
Edukasi Masyarakat Mengenai Ketepatan Pilihan Kosmetik Melalui Aplikasi BPOM Stiani, Sofi Nurmay; Yusransyah, Yusransyah; Udin, Baha; Harpan, Andri; Salsabillah, Audy Nursifa'atun; Wibirezkina, Aufalya; Aulia, Ayu; Anwar, Ade; Endah, Endah
Jurnal Pengabdian Pada Masyarakat Vol 10 No 3 (2025): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v10i3.1401

Abstract

Kosmetik sering digunakan oleh masyarakat Indonesia untuk memperindah tubuh, tetapi berpotensi beredar produk ilegal dan berbahaya. Tujuan kegiatan ini, yaitu memberikan edukasi kepada masyarakat tentang pemilihan kosmetik yang tepat dan penggunaan aplikasi BPOM. Kegiatan dilakukan dalam tiga tahap (perencanaan, pelaksanaan, evaluasi) kepada 20 peserta di Kampung Jagabaya. Peserta seluruhnya perempuan, mayoritas berusia 19-44 tahun dengan pendidikan SD/MI. Peningkatan pengetahuan signifikan dari rata-rata skor pre-test 28 menjadi post-test 74,7 (p=0,001). Edukasi meningkatkan pengetahuan masyarakat terkait kosmetik dan penggunaan aplikasi BPOM. Cosmetics are frequently used by Indonesians to enhance their bodies, but they have the potential to contain illegal and dangerous products. The purpose of this activity is to educate the public about choosing the right cosmetics and using the BPOM application. The activity was carried out in three stages (planning, implementation, evaluation) with 20 participants in Jagabaya Village. All participants were female, the majority aged 19-44 years with elementary school education. There was a significant increase in knowledge from an average pre-test score of 28 to a post-test score of 74.7 (p=0.001). Education increased public knowledge regarding cosmetics and the use of the BPOM application.
Co-Authors Achmad Fudholi Ade Anwar Ade Apriliani Adini, Syilvi Aditia Saeffurrohman Afifah Nur Shobah Afifah Nur Shobah Afifah Nur Shobah Agnes Syafera Agus Sulaeman Anas Subarnas Andri Harpan Anjani, Shabrina Talitha Apriliani, Ade Ashari, Elva Febri Audy Nursifa'atun Aufalya Wibirezkina Aulia, Ayu Ayuni, Eka Sirly Baha Udin Cahya, Wulan Candra Junaedi Chairani, Farahdina Dewi Intan Sri Rahayu Deya Adiby Nabillah Dharojatul Khasfah Effendi, Erwin Elfrida Ratnawati Endah Endah endah, endah Endi Muchyar Eneng Elda Ernawati Eneng Elda Ernawati Fajrin Noviyanto Fajrin Noviyanto Fajrin Noviyanto, Fajrin Farahdina, Chairani Fathiyati Fathiyati Fauzi, Andrian Maulana Fauzy, Adrian Maulana Ferdiyansyah, Ferdiyansyah Fifih Lutfiyah Ghina Annufus Hanifah Dwi Safitri Harpan, Andri Hasanah, Indah Ayu Nur Hayati, Farida Herawati, Fera Indriatmoko, Dimas Danang Ismiyati, Renditya Kelutur, Faruk Jayanto Kholifah, Eva Kuncoro, Banu Kurnia, Nia Marlina Latifah Nur, Rizki Leni Halimatusyadiah Lidiah, Mae Lutfiyah, Fifih Maharani, Sylvianti Maharani, Zahra Citra Marlina, Nia Masfuah, Imas Megawati, Sefi Meila Pertiwi Miftah Miftah, Miftah Mohammad Rizal Mohammad Rizal, Mohammad Muhamad Ichsan Fahlevy Nabillah, Deya Adiby Nasiti, Febriane Dwi Neneng Nasliah Nia Marlina Nita Rusdiana S.Farm., M.Sc, Apt Nur Shobah, Afifah Nurani, Agnes Wieanita Nurhayati, Ghina Siti Nurhikmah, Ihda Nurul Fitri, Nabila Ofsah, Olin Najilah Oktaviana Hadi, Agriyaningsih Perdi, Perdi Pratiwi, Linda Rani Pratiwi, Rossi Putri, Nabila Septiani Rahmawida Putri Renditya Ismiyati Renditya Ismiyati Renditya Ismiyati Rini Rumantir Ristiani, Yuanisa Rizkiana, Muhammad Dinta Rustiyani, Risa Sabilla, Aliffia Nur Saeffurrohman, Aditia Salsabillah, Audy Nursifa'atun Satibi . Seira, Trisya Selviani, Astri Septina Sumantri, Aulia Shabrina Talitha Anjani Shirly Kumala Shobah, Afifah Nur Siska Purnama Sari Siswa Setyahadi Siti Lailatu Zahroh Siti Marina Subchan, Mohamad Suci Nurainun Sumarlin US Sumarlin US Syifa Maulidia Rizqi Sylvi Addini Sylvianti Maharani Taofik Rusdiana US, Sumarlin Wibirezkina, Aufalya Yulistina, Isti Yusransyah, Yusransyah Zahroh, Siti Lailatu