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All Journal Ngayah: Majalah Aplikasi IPTEKS Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Pharmaceutical Journal of Indonesia Jurnal Karinov Widyadari : Jurnal Pendidikan Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Ilmiah Medicamento Medfarm: Jurnal Farmasi dan Kesehatan Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Mandala Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia Usadha Borneo Journal of Pharmacy Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal)
Megawati, Fitria
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Kajian Etnofarmasi Kelompok Masyarakat Banjar Saraseda Tampaksiring Gianyar Bali Puspita Wati, Ni Putu; Anita Dewi, Ni Luh Kade Arman; Suradnyana, I Gede Made; Kusuma Yuda, I Putu Era Sandhi; Cahyaningsih, Erna; Megawati, Fitria
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7376

Abstract

  The use of ethnopharmaceutical practices remains widespread in Bali, as this knowledge has been passed down through generations. Although the Balinese people still strongly uphold their traditional healing systems and have long utilized plants as medicinal ingredients, there is still limited research documenting the diversity of plant species recorded in the Usadha manuscripts along with their therapeutic uses. This study aimed to inventory medicinal plants that are still used by the community in Banjar Saraseda, Tampaksiring, Gianyar, Bali. The study employed a descriptive design, with data collected through interviews to obtain information from respondents regarding local plant names, therapeutic uses/indications, parts of the plant utilized, and methods of preparation and application. The data were analyzed descriptively and presented in tables. Based on the ethnopharmacological survey conducted in Banjar Saraseda, Tampaksiring, Gianyar, Bali, a total of 20 medicinal plant species were recorded. The most frequently used plant parts were leaves (75%), followed by rhizomes (15%) and fruits (10%). The primary methods of preparation included boiling (65%), pounding (15%), grating, crushing, brewing, and direct use (each 5%). Based on therapeutic indications, the plants were mainly used to treat fever (20%), muscle pain and gout (20%), hypertension (20%), skin itching (10%), diabetes (10%), and to manage wounds, diarrhoea, haemorrhoids, and gastritis (each 5%). This study demonstrates that the Banjar Saraseda community in Tampaksiring, Gianyar, Bali continues to preserve traditional knowledge in the use of medicinal plants that has been inherited through generations.
Tingkat Pengetahuan Penggunaan Obat Tradisional dalam Pengobatan Swamedikasi pada PKK Banjar Tegal Buah Denpasar Barat Purnama Sari, Ni Kadek Akari; Tangkas Suwantara, I Putu; Udayana Antari, Ni Putu; Megawati, Fitria; Dewi Agustini, Ni Putu
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7577

Abstract

  Treatment using traditional medicine has become integrated into Indonesian society and is used to treat health problems through self-medication. Traditional medicine is a nation's cultural heritage that needs to continue to be preserved and developed to support health development. This research aims to find out how self-medication uses traditional medicine in the PKK Banjar Tegal Buah West Denpasar. This type of research is quantitative survey research with data collection techniques using questionnaires and using a Likert scale in conducting surveys with questionnaire measuring instruments. This research was conducted from April to May 2023. The population in this study were all PKK mothers who had carried out self-medication using traditional medicine and the sample in this study was 100 respondents. The instrument used was a questionnaire sheet with 20 questions. Based on the results of research on the level of knowledge of the use of traditional medicine in 100 PKK respondents with the criteria for a good level of knowledge, 88 people (88%) while 12 people (12%) of respondents were included in the sufficient category.
Komunikasi dalam pemberian informasi obat Antari, Ni Putu Udayana; Megawati, Fitria; Agustini, Ni Putu Dewi; Mendra, Ni Nyoman Yudianti; Suena, Ni Made Dharma Shantini
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 7 No 3 (2024)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v7i3.21897

Abstract

Banyak penelitian menunjukkan terbatasnya informasi yang diberikan kepada pasien saat penyerahan obat di Apotek. Untuk itu perlu diadakan sosialisasi mengenai metode-metode komunikasi yang dapat digunakan untuk memberikan informasi obat agar komunikasi dapat berjalan efektif dan efisien waktu. Pengabdian dilaksanakan menggunakan metode CBPR (Community-Based Participatory Research) dengan melibatkan ApotekKu sebagai salah satu apotek jaringan untuk memberikan pengaruh yang lebih luas bagi masyarakat. Peserta adalah tenaga kefarmasian di seluruh jaringan ApotekKu. Peserta diberikan sosialisasi mengenai pentingnya pemberian informasi obat sesuai dengan standar yang berlaku dan beberapa teknik komunikasi yang dapat diterapkan dalam pelayanan di apotek. Untuk membantu penyampaian informasi kepada pasien, apotek mitra dibantu dengan penyediaan media pemberian informasi obat berupa video dan buku. Sosialisasi dihadiri oleh 100 peserta, analisis pre-test dan post-test peserta sosialisasi menunjukkan adanya peningkatan pengetahuan yang signifikan pada indikator pemberian informasi obat (p-value <0,001) maupun pada indikator teknik komunikasi (p-value = 0,032) menggunakan uji Wilcoxon dengan taraf kepercayaan 95%. Kegiatan pelatihan yang berkesinambungan perlu dilaksanakan untuk melanjutkan materi yang telah disampaikan.
Perbandingan Mutu Fisikokimia Virgin Coconut Oil (VCO) dengan Metode Enzimatis dan Fermentasi Alami Mutu Fisikokimia Virgin Coconut Oil (VCO) dengan Metode Enzimatis dan Fermentasi Alami Dewi Maharani Indah Sari, Ni Komang; Chandra Wibawa, Agung Ari; Pramitha, Dewa Ayu Ika; Megawati, Fitria
Usadha Vol 3 No 3 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i3.7498

Abstract

VCO is obtained from fresh, old coconut (Cocos nucifera L) flesh through a simple process without heating. Making VCO can be done by several methods, namely enzymatic methods and natural fermentation. The enzyme used in the manufacture of VCO is bromelain enzyme powder. The purpose of this study was to determine differences in the physicochemical quality of Virgin Coconut Oil (VCO) obtained by natural fermentation methods and VCO obtained by enzymatic methods adding 10% bromelain enzyme. The type of research used is experimental research conducted in the laboratory. The results obtained were then evaluated to determine the physicochemical quality of enzymatic VCO and natural fermentation. Physicochemical test parameters include a water content test performed by the gravimetric method and a free fatty acid test carried out by the titrimetric method. Based on the research that has been done, the highest average yield of VCO with the addition of bromelain enzyme powder is (24.45 ± 0.06) %. The results of the pH test on sample 1 (S1) and sample 2 (S2) obtained a pH value of 6. Testing the water content of the two samples S1 and S2 obtained results (4.018 ± 1.93) and (7.949 ± 2.57) %, with statistical testing getting p> 0.05 where there is no significant difference between the two samples. Tests for free fatty acid levels in samples S1 and S2 yielded (0.0086 ± 0.003055) % and (0.0106 ± 0.004619) %, with statistical testing yielding p > 0.05 after being tested by Kruskal Wallis, no there is a significant difference between the two samples. The enzymatic production of VCO has the advantage of obtaining more yield with the same quality as naturally fermented VCO.
PENGKAJIAN RESEP SECARA ADMINISTRATIF BERDASARKAN PERATURAN MENTERI KESEHATAN RI NO 35 TAHUN 2014 PADA RESEP DOKTER SPESIALIS KANDUNGAN DI APOTEK STHIRA DHIPA Megawati, Fitria; Santoso, Puguh
Jurnal Ilmiah Medicamento Vol 3 No 1 (2017): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v3i1.1042

Abstract

Dalam alur pelayanan resep, apoteker wajib melakukan skrining resep yang meliputi skrining admninstratif, kesesuaian farmasetis, dan kesesuian klinis untuk menjamin legalitas suatu resep dan meminimalkan kesalahan pengobatan. Aspek admnistratif resep dipilih karena merupakan skrining awal pada saat resep dilayani di apotek karena mencakup seluruh informasi di dalam resep yang berkaitan dengan kejelasaan tulisan obat, keabsahan resep, dan kejelasan informasi di dalam resep. Akibat ketidaklengkapan admnistratif resep bisa berdampak buruk bagi pasien, merupakan tahap skrining awal guna mencegah adanya medication error. Penelitian ini bertujuan untuk mengetahui kelengkapan administratif resep dokter spesialis kandungan memenuhi ketentuan kelengkapan resep menurut PMK No 35 tahun 2014. Penelitian yang dilakukan bersifat deskriptif dan pengambilan data dilakukan secara retrospektif. Pengambilan data dilakukan dengan mengamati seluruh resep yang masuk selama periode Januari-Mei 2015 yang ditulis oleh dokter spesialis kandungan. Dilakukan skrining administratif terhadap 350 resep dokter spesialis kandungan dengan mengisi tabel pengambilan data (check list), sesuai dengan aspek kelengkapan resep yang ditinjau. Data yang di peroleh akan dikumpulkan dan disajikan secara deskriptif. Dari hasil penelitian menunjukan persentase kejadian ketidaklengkapan resep di apotek Sthira Dhipa yaitu umur pasien 62%, jenis kelamin pasien 100%, berat badan pasien 100%, SIP dokter 100%, alamat pasien 99,43%, paraf dokter 19%, serta tanggal resep 1%, nama pasien, nama dokter, alamat dokter, serta no telepon dokter yang dituliskan oleh dokter telah mencapai 100 %. Kelengkapan resep dokter spesialis kandungan belum memenuhi ketentuan kelengkapan admnistratif resep menurut PMK No 35 tahun 2014.
KORELASI ANTARA TINGKAT PENDIDIKAN DAN HARAPAN SERTA PERSEPSI PASIEN DALAM PELAYANAN KEFARMASIAN DI APOTEK “X” DI DAERAH SEMINYAK Antari, Ni Putu Udayana; Megawati, Fitria; Suwantara, I Putu Tangkas
Jurnal Ilmiah Medicamento Vol 3 No 1 (2017): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v3i1.1043

Abstract

Apotek selaku penyedia jasa dituntut untuk dapat memberikan pelayanan kefarmasian yang terbaik. Apotek dituntut untuk dapat memenuhi harapan pasien sehingga pasien puas terhadap pelayanan yang diberikan. Tingkat pendidikan seseorang mempengaruhi tingkat pengetahuan pasien, Pengetahuan seseorang mempengaruhi sudut pandangnya dalam menilai suatu pelayanan kefarmasian yang diperoleh. Dengan demikian penelitian ini bertujuan untuk mengetahui hubungan antara tingkat pendidikan pasien dan harapan serta persepsi antara pasien terhadap pelayanan kefarmasian yang dilakukan oleh Apotek “X’’ di daerah Seminyak. Penelitian ini menggunakan rancangan cross sectional yang dilaksanakan melalui penyebaran kuesioner yang memuat harapan dan persepsi kepada pasien yang berkunjung ke Apotek “X” di daerah Seminyak. Kuesioner memuat pernyataan yang terbagi dalam 5 dimensi yaitu: reliability, responsiveness, assurance, tangibles, dan empathy. Kuesioner yang diisi responden diberi skor menggunakan skala Likert. Hasil penelitian menunjukkan bahwa ada korelasi signifikan antara tingkat pendidikan dan harapan terhadap pelayanan kefarmasian dengan arah korelasi positif dan tingkat korelasi lemah. Korelasi antara tingkat pendidikan terhadap pelayanan kefarmasian dan persepsi menunjukkan hasil yang signifikan dengan arah korelasi positif dan tingkat korelasi lemah.
Pengaruh Polimorfisme Gen terhadap Risiko Penyakit Gagal Ginjal Kronis: Narrative Review Handani, Dewa Ayu Sri; Megawati, Fitria
Usadha Vol 3 No 3 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i3.10956

Abstract

Chronic Kidney Disease (CKD) is an escalating global health issue, particularly in Indonesia. CKD is characterized by a progressive and irreversible decline in renal function, with diabetes mellitus and hypertension as primary risk factors. Genetic polymorphisms, variations in DNA sequences that affect gene function and protein expression, play a critical role in CKD risk and progression. This narrative review examines the role of genetic polymorphisms in CKD risk based on available literature. Scientific articles were sourced from PubMed, ScienceDirect, Google Scholar, and Scopus using keywords related to genetic polymorphisms and CKD. From the 441 articles identified, selection was based on relevance, sample size, and article completeness. Several genetic polymorphisms were found to have significant associations with increased CKD risk, including Renalase (rs2296545), GSTO1 (rs2164624), GSTO2, MMP3 (rs35068180), and MGP (rs4236), among others such as CYP24A1, GPX1, UMOD, CYP2C8, CYP4A11, EPHX2, SPP1, and BGLAP. These polymorphisms influence mechanisms such as blood pressure regulation, oxidative stress, inflammation, and tissue calcification, all contributing to CKD progression. In conclusion, genetic polymorphisms are crucial in CKD risk, offering insights for more personalized approaches in diagnosing, preventing, and treating this condition. These findings support the development of more effective, genetics-based treatment strategies in the future.
An Overview of knowledge level of adolescent girls about anemia disease and prevention in Badung area, Bali Sari, Gusti Ayu Putu Laksmi Puspa; Wibowo, Yosi Irawati; Yana, I Gusti Agung Ari Kusuma; Megawati, Fitria
Pharmaceutical Journal of Indonesia Vol. 10 No. 2 (2025)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Adolescent anemia in Indonesia is still a high health problem, despite the implementation of government programs related to adolescent anemia prevention. Knowledge is one of the factors and influences the success of anemia prevention programs in adolescents. Objective: To provide an overview of knowledge related to blood supplement tablets and anemia in adolescent girls in Badung area. Methods: A survey study using a questionnaire was conducted on 193 adolescent girls enrolled in one of the junior high schools in Badung. There were twenty knowledge questions related to blood supplement tablets and anemia. Data were analyzed descriptively based on the variables measured. Results: The knowledge level of adolescent girls mostly had sufficient knowledge (74.6%), good knowledge (11.9%) and poor knowledge (13.5%). Conclusion: In this study, there were still adolescent girls who had insufficient knowledge. Educational efforts need to be made in various approaches to improve the knowledge of adolescent girls.
An Overview of knowledge level of adolescent girls about anemia disease and prevention in Badung area, Bali Sari, Gusti Ayu Putu Laksmi Puspa; Wibowo, Yosi Irawati; Yana, I Gusti Agung Ari Kusuma; Megawati, Fitria
Pharmaceutical Journal of Indonesia Vol. 10 No. 2 (2025)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Adolescent anemia in Indonesia is still a high health problem, despite the implementation of government programs related to adolescent anemia prevention. Knowledge is one of the factors and influences the success of anemia prevention programs in adolescents. Objective: To provide an overview of knowledge related to blood supplement tablets and anemia in adolescent girls in Badung area. Methods: A survey study using a questionnaire was conducted on 193 adolescent girls enrolled in one of the junior high schools in Badung. There were twenty knowledge questions related to blood supplement tablets and anemia. Data were analyzed descriptively based on the variables measured. Results: The knowledge level of adolescent girls mostly had sufficient knowledge (74.6%), good knowledge (11.9%) and poor knowledge (13.5%). Conclusion: In this study, there were still adolescent girls who had insufficient knowledge. Educational efforts need to be made in various approaches to improve the knowledge of adolescent girls.
Identifikasi Senyawa Fitokimia dan Uji Aktivitas Antioksidan pada Cascara (Coffea arabica L.) Sasadara, Maria Malida Vernandes; Cahyaningsih, Erna; Yuda, Putu Era Sandhi Kusuma; Handani, Dewa Ayu Sri; Dewi, Ni Luh Kade Arman Anita; Megawati, Fitria; Tirtayasa, Gede Agus Ari
Usadha Vol 4 No 1 (2025): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v4i1.12181

Abstract

Cascara refers to the dried husk of coffee cherries. It has garnered significant attention in recent research due to its phytochemical composition and potential health benefits. Several studies have highlighted the presence of bioactive compounds and the antioxidant activity exhibited by cascara. This study aims to investigate the phytochemical content and antioxidant potential of cascara. The cascara was extracted using the maceration method with 96% ethanol, followed by phytochemical screening for alkaloids, flavonoids, tannins, saponins, terpenoids, steroids, and quinones using standard color reactions in test tubes. Antioxidant activity was assessed via the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay, with ascorbic acid as a reference compound. The phytochemical profile of the extract was identified using gas chromatography-mass spectrometry (GC-MS). The findings indicated that cascara contains alkaloids, flavonoids, tannins, saponins, and triterpenoids. GC-MS analysis identified caffeine, hexadecanoic acid (methyl ester), and hexadecanoic acid (ethyl ester) as the predominant compounds in cascara. The antioxidant activity test using the DPPH method demonstrated that the ethanol extract of cascara possesses moderate antioxidant potential, with an average IC50 value of 108.49 ± 1.28 ppm. Ascorbic acid, the reference compound used in this study, yielded an IC50 of 2.53 ppm, categorized as very strong. This research underscores cascara’s potential as a valuable source of antioxidants with significant health benefits, influenced by geographic factors affecting its bioactive compound profile. Consequently, cascara holds promise for further development as a raw material for functional health-promoting products.
Co-Authors Agung Ari Chandra Wibawa Agus Adrianta, Ketut Agustini, Ni Putu Dewi Amesti Dewi , Ni Made Wahyuni Anita Dewi, Ni Luh Kade Arman Antara, I Putu Satria Artini, Ni Putu Eka Candraningrat, I Dewa Agung Ayu Diva Chandra Wibawa, Agung Ari Cintya Purnama Sari, Ni Wayan Darmayanti, Ni Wayan Debby Juliadi Dewa Ayu Ika Pramitha Dewi Agustini, Ni Putu Dewi Maharani Indah Sari, Ni Komang Dewi, Ni Made Sintia Dwipayanti, Ni Kadek Sari Ekayanti, Ni Luh Firda Erna Cahyaningsih Firda Ekayanti, Ni Luh Fredinan Yulianda Handani, Dewa Ayu Sri I Made Dedy Ariawan I Putu Tangkas Suwantara Krismayanti, Ni Luh Putu Dian Linda Paramita, Ni Kadek Mendra, Ni Nyoman Yudianti Meriyani, Herleeyana Ni Luh Kade Arman Anita Dewi Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Made Sukma Sanjiwani Ni Nyoman Wahyu Udayani NI PUTU AYU MIRAH MARIATI Ni Putu Udayana Antari Ni Wayan Trisna Dewi P Purwanto Paramitha, Dewa Ayu Ika Prameswari, Putu Nimas Diyah puguh santoso, puguh Purnama Sari, Ni Kadek Akari Puspita Wati, Ni Putu Putra Hilmi Prayitno Putra, I Made Agus Sunadi Putu Era Sandhi Kusuma Yuda Ratna Wulandari Sasadara, Maria Malida Vernandes Suardika, I Wayan Gede Sukamto, Ika Sumiyarsi Suradnyana, I Gede Made Susianti, Luh Tirtayasa, Gede Agus Ari Udayana Antari, Ni Putu Wardani, I Gusti Agung Ayu Kusuma Wibowo, Yosi Irawati Widiari, Ni Nyoman Sri Wintariani, Ni Putu Wiradana, Dewa Gde Adi Wiryani, Luh Santhi Utami Yana, I Gusti Agung Ari Kusuma