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All Journal Syntax Literate: Jurnal Ilmiah Indonesia The Southeast Asian Journal of Midwifery Bunda Edu-Midwifery Journal (BEMJ) Holistik Jurnal Kesehatan Healthcare Nursing Journal Journal of Telenursing (JOTING) JPK: Jurnal Proteksi Kesehatan Edu Masda Journal Edu Dharma Journal: Jurnal penelitian dan pengabdian masyarakat INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Ibu dan Anak NURSING ANALYSIS: Journal of Nursing Research Journal of Maternal and Child Health Science Pharmaceutical Science Journal EDU RMIK Jurnal Edukasi Rekam Medis Informasi Kesehatan Jurnal Ilmiah Kesehatan BPI JOURNAL OF Pharmacy and Tropical Issues
Rahmi Junaida
Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang
Humanities Dentistry Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Analisis hubungan ketepatan penggunaan obat antihipertensi dengan keberhasilan terapi pada pasien hipertensi disertai diabetes melitus Suny Koswara; Junaida Rahmi; Nurwulan Adi Ismaya; Ikhsanul Kahfi
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 1 (2026): May Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i1.3308

Abstract

Background: Hypertension and diabetes mellitus are two common degenerative diseases that increase the risk of cardiovascular complications. Rational use of antihypertensive medications can achieve successful therapy. Purpose: To determine the relationship between the appropriate use of antihypertensive drugs and the success of therapy in respondents with hypertension accompanied by diabetes mellitus. Method: Using a descriptive observational cross-sectional design, where data were collected retrospectively through patient medical records. The study was conducted at Qadr Hospital from July to December 2024. The sample consisted of 101 patients who met the inclusion criteria. Data were analyzed anivariately and bivariately using the chi-square test. Results: The characteristics are dominated by women (63.4%), age 45-59 (60.4%), and housewives (43.6%). The profile of antihypertensive drug use is mostly a combination of two drugs (47.5%), and single therapy (26.7%). Evaluation of the rationality of drug use shows that the indication is correct (100.0%), the dose is correct (100.0%), the drug is correct (98.0%), and the patient is correct (91.1%). The results of the chi-square analysis obtained a value (p-value = 0.000). Conclusion: There is a relationship between the accuracy of drug use and the success of therapy in hypertensive patients accompanied by diabetes mellitus.                                                                  Keywords: Antihypertensive Drugs; Diabetes Mellitus; Hypertension; Rationality,Therapy Success.   Pendahuluan: Hipertensi dan diabetes melitus merupakan dua penyakit degeneratif yang sering terjadi dan meningkatkan risiko komplikasi kardiovaskular. Penggunaan obat antihipertensi secara rasional dapat mencapai keberhasilan terapi. Tujuan: Untuk mengetahui hubungan antara ketepatan penggunaan obat antihipertensi dengan keberhasilan terapi pada responden hipertensi disertai diabetes melitus. Metode: Menggunakan observasional deskriptif dengan desain potong lintang (cross-sectional), Dimana data dikumpulkan secara retrospektif melaui rekam medis pasien. Penelitian dilaksanakan di Rumah Sakit Qadr periode Juli - Desember 2024. Sampel terdiri dari 101 responden yang memenuhi kriteria inklusi. Data dianalisis secara anivariat dan bivariat dengan uji chi-square. Hasil: Menunjukkan bahwa karakteristik didominasi oleh Perempuan (63.4%), usia 45-59 (60.4%), dan pekerjaan IRT (43.6%). Profil penggunaan obat antihipertensi terbanyak dengan kombinasi dua obat (47.5%). Dan terapi Tunggal (26.7%). Evaluasi rasionalitas penggunaan obat menunjukkan tepat indikasi (100%), tepat dosis (100%), tepat obat (98.0%), tepat pasien (91.1%). Hasil analisis chi-square didapat nilai (p-value = 0.000). Simpulan: Terdapat hubungan antara ketepatan penggunaan obat dengan keberhasilan terapi pada pasien hipertensi disertai dengan diabetes melitus.   Kata kunci: Diabetes Melitus; Hipertensi; Keberhasilan Terapi; Obat Antihipertensi; Rasionalitas.
Co-Authors AA Sudharmawan, AA Akub Selvia Aliyah, Hopipah Hilmatul Amanda Rischa Ramadihina Amelia Nurul Hakim Amir, Arni Anggraeni, Reska Widya Anisa, Fitri Nur Annisa Amalia Hanifa Apriyanti, Rini Arni Amir Asri Noviyanti Augesti Erisna Aulia Nadya Rizki Imansari Ayu Lestari Ayu, Mila Putri Berliana, Azzahra CHUSNI, ITA Desy Darmayanti DEWI FITRIANI Elvi Elvi Eryati Darwin Esthy Rahman Asih Evi Kaderani Barutu Fadillah, Firdayani FADMIYANOR, ISYE Franciska, Yunetra Gama Bagus Kuntoadi Heni Yohandini Herawati, Aryana Ida Listiana IKADA SEPTI ARIMURTI Ikhsanul Kahfi Ima Rusdiana Imansari, Aulia Nadya Rizki Indah Purnama Sari Isrowiyatun Daiyah Isye Fadmiyanor Jasmi Jasmi Jasmi Jasmi Jasmi Jasmi Juniar, Shella Juraida Roito Hrp Kasumawati, Frida Katmini, Katmini Khairunnisa, Firyal Kristina, Indah Lathifina, Yashna Meutia LESTARI, R TRI RAHAYUNING LESTARI, SANTI Lily Restusari Liza Puspa Dewi Maghfirahmah Amsyah Putri Marselina Astitin Nembo Melinda Susanti S Melly Wardanis Melsa Nilmalasari Meri, Diana Miftah Parid Firmansyah Mila Putri Ayu Mita Puspitasari Muhammad Agus Muljanto Nabilah Diah Srikandi Ni Bodro Ardi Noviyanti, Asri Nur Hasanah Nurhaliza Nurwulan Adi Ismaya Puji, Lela Kania Rahsa Putri Handayani Setyaningsih R Tri Rahyuning Lestari RIRIS ANDRIATI rofiqoh rofiqoh Rr. Kusuma Nurin Husna Rully Hevrialni Rumondang, Christin Ruslan, Sherin Sari, Yollin Noviana Septiana, Diah Ayu setyaningsih, putri Simanjuntak, Farida Mentalina Siti Aisah Siti Novy Romlah Sri Haryanto Stephani Stephani Suny Koswara Timor Utama Uswatun Hasanah Vivi Juwitasari Werfete, Anggraeny Rahma Yeni Aryani Yulia Fitri Yunetra Franciska