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All Journal Humaniora Lensa: Kajian Kebahasaan, Kesusastraan, dan Budaya MEDIA MEDIKA INDONESIANA Jurnal Anestesi Perioperatif Folia Medica Indonesiana Journal of Agromedicine and Medical Sciences Biomedika Briliant: Jurnal Riset dan Konseptual Journal of Medicine and Health Care : Jurnal Ilmiah Ilmu Kesehatan Oto Rhino Laryngologica Indonesiana Lembaran Sejarah Majalah Biomorfologi (Biomorphology Journal) Jurnal Riset Akuntansi dan Manajemen Malahayati (JRAMM) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Indian Journal of Forensic Medicine & Toxicology Masyarakat Indonesia PROFESSIONAL HEALTH JOURNAL Journal Philosophy of Law Journal of Medicine and Health
Bambang Purwanto
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Religion Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Pengaruh tonsilektomi terhadap ukuran dan ekspresi IL-6 tonsil lingualis pada pasien OSA Sally Mahdiani; Teti Madiadipoera; Iwin Sumarman; Bambang Purwanto
Oto Rhino Laryngologica Indonesiana Vol 42, No 2 (2012): Volume 42, No. 2 July - December 2012
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.247 KB) | DOI: 10.32637/orli.v42i2.29

Abstract

Background: Obstructive sleep apnea (OSA) is a sleep breathing disorder caused by upper airway  obstruction. It occurs on 51% adult and could cause systemic side effects. Hypertrophy of the palatine  and lingual tonsils cause upper airway obstruction and increasing cytokine IL-6 production. Obstruction and inflammation products have an important role in causing OSA. Inflammation of the palatine tonsil causes lingual tonsil to be inflamed. Purpose: To find out the impact of tonsillectomy on size and IL-6 expression of lingual tonsil. Method:The quasiexperimental open label pre and post test design was done on August 2010 – October 2011. There were 20 adult subjects with snoring, palatine and lingual tonsil hypertrophy. All subjects filled the Epworth Sleepiness Scale (ESS) questionnaire, underwent ENT examination and biopsy using fiber optic rhinolaryngoscope. Immunohistochemistry examination for IL-6  were performed on all biopsy specimens. Results: There is highly significant improvement on lingual  tonsil size score from 3 to 1 after tonsillectomy. IL-6 expression was significantly decreased from 12 to 2 after tonsillectomy. ESS score was also significantly decreased from 16 to 5. The reducing size of lingual tonsil correlates with decreasing of IL-6 expressions. Conclusion:Tonsillectomy on OSA patients reduced the IL-6 expression of the lingual tonsil and that cause the reducing of its size. Decreasing of obstruction and inflammation could lead to the decrease of the ESS score. Keywords: OSA, tonsillectomy, Epworth Sleepiness Scale, lingual tonsil size, IL-6 expression    Abstrak :  Latar belakang: Henti napas obstruktif saat tidur (OSA) merupakan gangguan napas saat tidur yang terjadi karena obstruksi saluran napas atas. Keluhan ini terjadi pada 51% orang dewasa dan menimbulkan efek samping sistemik berat. Pembesaran ukuran tonsil palatina dan tonsil lingualis akan menyebabkan obstruksi saluran napas atas dan mengakibatkan peningkatan produksi IL-6, sehingga akan menyebabkan OSA. Inflamasi yang terjadi pada tonsil palatina membuat tonsil lingualis mengalami inflamasi. Tujuan: Untuk melihat pengaruh tonsilektomi terhadap ukuran dan ekspresi IL-6 tonsil lingulis. Metode: Penelitian quasiexperimental open label pre and post test design di Poliklinik IK. THT-KL RSHS Bandung sejak Agustus 2010 – Oktober 2011. Subjek 20 orang dewasa dengan keluhan mendengkur, pembesaran tonsil palatina dan tonsil lingualis. Seluruh subjek mengisi kuesioner skala kekantukan Epworth (Epworth Sleepiness Scale/ESS), biopsi tonsil lingualis dengan rinolaringoskopi serat optik lentur dan imunohistokimia IL-6 jaringan biopsi. Hasil: Didapatkan perbaikan yang sangat bermakna skor ukuran tonsil lingualis sebelum tonsilektomi (3) dibandingkan setelah tonsilektomi (1). Nilai ekspresi IL-6 menurun sangat bermakna dari 12 menjadi 2. Skor ESS menurun secara bermakna dari 16 menjadi 5. Pengecilan ukuran tonsil lingualis berhubungan dengan penurunan ekspresi IL-6. Kesimpulan: Tonsilektomi pada pasien OSA dapat menurunkan ekspresi IL-6 pada tonsil lingualis, sehingga ukuran tonsil lingualis mengecil. Hilangnya obstruksi dan inflamasi mengakibatkan skor ESS menurun. Kata kunci: henti napas obstruktif saat tidur, tonsilektomi, Epworth Sleepiness Scale, ukuran tonsil lingualis, ekspresi IL-6
‘Guided Economics’: The Construction of Postcolonial Indonesian Political Images, 1950s-1960s Bambang Purwanto
Lembaran Sejarah Vol 10, No 1 (2013)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (513.522 KB) | DOI: 10.22146/lembaran-sejarah.23655

Abstract

This contribution is about how political images created in Indonesia in the immediate aftermath of decolonization acquired a divisive rather than a unifying character. The answer is sought in the tendency towards guidance that came to the fore during the Guided Democracy and Guided Economy. The analysis starts with matters of periodization arguing that the Guided Democracy and Guided Ecoomy in fact began in early 1957. Then, the economic content of the newly created post-colonial images is surveyed. Finally, the article takes a closer look at the precise role played in this process by Soekarno and Hatta. The article concludes by pointing out the great diversity of perceptions of the Guided Economy and also the relatively weak economic substance in these perceptions.
COMPLEX CHALLENGES IN HANDLING REFUGEES IN INDONESIA: THE DILEMMA OF RATIFYING THE 1951 REFUGEE CONVENTION Bambang Purwanto
Journal Philosophy of Law Vol 4, No 2 (2023)
Publisher : Universitas 17 Agustus 1945 Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56444/jpl.v3i7.4206

Abstract

This article is a conceptual article created with the aim of analyzing the problems faced by the Indonesian government concerning refugees and identifying challenges in implementing the 1951 Refugee Convention and its 1967 Protocol. The results of the discussion indicate that addressing the refugee issue in Indonesia is highly complex. Although ratifying the 1951 Refugee Convention and its Protocol can substantially protect the human rights of refugees, its implementation in Indonesia faces various challenges caused by several factors, such as the high population density in Indonesia and the absence of laws governing local integrity, leading to difficulties in granting equal rights between refugees and Indonesian natives. Refugees must meet specific requirements according to the Republic of Indonesia Law No. 12 of 2016 on citizenship to have the same rights as Indonesian citizens. Additionally, from an economic perspective, refugee migration impacts Indonesia's financial budget. The aspects of security and social culture are essential considerations, as an increasing number of refugees may cause conflicts with the indigenous population and threaten Indonesia's cultural identity. Although the 1951 Refugee Convention provides standard rights for refugees, the Indonesian government finds it challenging to ratify it due to various obstacles, such as religious differences, marriage laws, labor absorption, and budget limitations. Therefore, the Indonesian government needs to carefully consider before ratifying the 1951 Refugee Convention. Thus, in addressing this complex situation, choosing to act as a transit country and providing protection within its capacity is a wise step in facing this refugee issue.
EFEK AKUT LATIHAN SENAM PERSADIA 1 TERHADAP KADAR MALONDIALDEHYDE DAN KADAR CREATINE KINASE Yuan Guruh Pratama; Gadis Meinar S; Bambang Purwanto
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 8, No 3 (2020): EDITION NOVEMBER 2020
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v8i3.1291

Abstract

Diabetes dance of Persadia 1 is one Physical activity in sports involving muscle contraction especially in eccentric contractions will potentially increase malondialdehyde and creatine kinase serum levels. The aim of this study was to determine the effect acute exercise Diabetes Dance of Persadia 1 on malondialdehyde and creatine kinase serum levels. This research was experimental fields with pretest – posttest control group design. Malondialdehyde serum lavels were measured using TBARS, while creatine kinase serum levels using ELISA. Paired – t test shows there was a significant decrease in MDA (p = 0,006) and CK (p = 0,033) serum levels, but from the results of the difference test between groups showed no significant differences between treatment group (p = 0,163) control group (p = 0,137). We can conclude there was a decrease in malondialdehyde and creatine kinase serum levels after being given Diabetes Dance of Persadia 1, but did not show significant differences between treatment and control group if only given onetime Diabetes Dance of Persadia 1 exercise.
The Effect of Intravenous Glutamine Administration in Lowering AIF Expression in Renal Tubular Cells Raihan Akbar Muhammad; Imam Susilo; Eko Budi Koendhori; Bambang Purwanto
Majalah Biomorfologi Vol. 35 No. 1 (2025): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v35i1.2025.21-28

Abstract

Highlights Glutamine, an amino acid, can help mitigate the side effects of cisplatin by boosting glutathione (GSH) levels, an antioxidant that counteracts oxidative stress. By reducing AIF protein expression and apoptosis, glutamine may protect kidney cells from cisplatin toxicity, potentially improving the safety of chemotherapy. Background: Cisplatin, a widely used chemotherapy that is effective for many forms of cancer, has nephrotoxic qualities that can reduce renal function. Due to its side effects, the usage of cisplatin is limited by its dose. Glutamine, an amino acid, possesses properties that can counteract the nephrotoxicity of cisplatin. Objective: This study aimed to analyze the effect of intravenous glutamine administration on the decrease of AIF expression and apoptosis in intraglomerular mesangial cells of cisplatin-exposed rats. Material and Method: Samples (n) consisting of 30 rats were divided into 3 groups, with each group containing 10 rats. Group P0 received no treatment, group P1 received an injection of cisplatin on the 7th day, and group P2 received glutamine on the 1st–7th day and an injection of cisplatin on the 7th day. After 72 h, the tissue samples were immunohistochemically processed and then observed under a light microscope with 400x magnification. AIF expression and apoptosis were measured in the Allred/H score. Result: AIF expression results were: P0 = 4,35(2,2-5,4); P1 = 5,9(4,8-6,3); P2 = 5,25(2,4-5,8). The AIF expression of P2 was found to be significantly lower (p = 0.008) than P1. Apoptosis results were: P0 = 5,2(4,7-5,5); P1 = 6,4(6,1-7,1); P2 = 5,7(4,8-5,9). The apoptosis level of P2 was found to be significantly lower (p = <0.0001) than P1. Strong correlations between the decrease in AIF expression and the apoptosis level were found (p = <0.0001). Conclusion: Glutamine contributes to the decreased AIF expression and apoptosis in intraglomerular mesangial cells of cisplatin-exposed rats.
Differences in Physical Activity Density Between Pregnant Women with Gestational Diabetes Mellitus (GDM) and Normal (Non-GDM) Pregnant Women: A Comparative Study Rohmatul Ummah; Muhammad Ilham Aldika Akbar; Bambang Purwanto
PROFESSIONAL HEALTH JOURNAL Vol. 7 No. 1 (2025): In Progress issue
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v7i1.1008

Abstract

Background: Gestational diabetes mellitus (GDM) is a condition of impaired glucose tolerance that leads to high blood sugar levels and is diagnosed for the first time during pregnancy, with varying degrees of severity. Insufficient physical activity is one of the top global risk factors for premature death. During pregnancy, a lack of physical activity and excessive weight gain are independent risk factors for maternal obesity and related complications, including gestational diabetes mellitus (GDM).Objectives: The aim of this study was to compare the physical activity density between pregnant women diagnosed with gestational diabetes mellitus (GDM) and those with normal pregnancies.Methods: This study utilized an observational analytical approach with a comparative design. A purposive sampling technique was employed, with 32 participants in the case group and 32 in the control group. The research was conducted between August and October 2024 at the Obstetrics and Gynecology clinic of Airlangga University Hospital. Data were analyzed using the non-parametric Mann-Whitney Test.Results: The analysis using the Mann-Whitney Test showed a significant p-value of 0.002, indicating a difference in the physical activity density between pregnant women with gestational diabetes mellitus (GDM) and those with normal pregnancies.Conclusion: Pregnant women without gestational diabetes mellitus (GDM) have higher physical activity density compared to those with gestational diabetes mellitus (GDM). It is suggested that future research adopt an experimental approach, especially focusing on interventions to promote physical activity during pregnancy.
POTENCY OF VINEGAR THERAPY IN OTOMYCOSIS PATIENTS Eman Sulaiman; Bambang Purwanto; Lina Lasminingrum; Yussy Afriani Dewi; Sally Mahdiani
Journal of Medicine and Health Vol 1 No 2 (2015)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v1i2.509

Abstract

Otomycosis is an outer ear canal infection caused by fungi. Clinicians are trying to find out the most effective antifungal drug for treating otomycosis. Traditionally Apple cider vinegar has been used for the treatment of various diseases, including antifungal.The high cost in otomycosis treatment effort, long duration of treatment, high recurrence rate, and the difficulty in the application of drugs in the otomycosis treatment have encouraged the researcher to do this study. Having evaluated  the improvement of clinical symptoms, otoscopy view and examination of KOH 10% in patients receiving apple cider vinegar therap, this study uses descriptive study design of four otomycosis patients in the ORL HNS outpatient clinic of Hasan Sadikin Hospital Bandung from July to August 2014. Having evaluated a clinical symptoms improvement, it is found out that there is an increase of otoscopy view and examination of KOH 10% in patients receiving apple cider vinegar. In other words, there is an Improvement of clinical symptoms, otoscopy view, and examination of KOH 10% in patients receiving apple cider vinegar therapy. Topical apple cider vinegar therapy gives a good result in the improvement of clinical symptom,otoscopy view, and examination of KOH 10% in otomycosis  patients. Keywords: otomikosis, sign and symptoms improvement, apple cider vinegar.
Characteristic of Intratemporal Complication in Chronic Suppurative Otitis Media Patient with and without Cholesteatoma at Hasan Sadikin General Hospital Bandung Ilman F Martanegara; Bambang Purwanto; Shinta F Boesoirie
Journal of Medicine and Health Vol 2 No 6 (2020)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v2i6.2763

Abstract

Otitis media supuratif kronis (OMSK) merupakan penyakit telinga umum di negara-negara berkembang. Kasus OMSK dengan kolesteatoma sering disebut sebagai tipe bahaya. Tujuan penelitian ini untuk mengetahui karakteristik komplikasi intratemporal pada pasien OMSK dengan dan tanpa kolesteatoma di Poliklinik Telinga Hidung Tenggorok Bedah Kepala Leher (THT-KL) Rumah Sakit Hasan Sadikin (RSHS) Bandung. Penelitian ini merupakan penelitian deskriptif retrospektif dari pasien yang datang ke poliklinik THT-KL RSHS Bandung periode 2014-2017. Diagnosis ditegakkan berdasarkan anamnesis, pemeriksaan fisik, dan penunjang radiologi. Didapatkan 791 kasus baru OMSK; pria (51,20%), sebanyak 30,59% kasus berada di rentang usia 21-30. Gejala dan tanda klinis yang paling sering terjadi adalah telinga berair (70,92) %, tipe gangguan dengar yang paling sering terjadi adalah tuli konduktif (83,94%). Pada proyeksi foto Schuller, 64,72 % menunjukkan gambaran mastoiditis kronis dengan kolesteatoma. Dari hasil kultur dijumpai 19,97 % kasus disebabkan oleh Pseudomonas aeroginosa. Komplikasi mastoiditis didapatkan pada 86,34%. Pada operasi Canal Wall Down ditemukan kolesteatoma pada 60, 42% kasus. Komplikasi terbanyak intratemporal pasien OMSK dengan dan tanpa kolesteatoma adalah mastoiditis kronis. Simpulan, komplikasi terbanyak intratemporal pasien OMSK dengan dan tanpa kolesteatoma adalah mastoiditis kronis. Profil penderita OMSK tipe bahaya dengan komplikasi intratemporal di RSUP Dr. Hasan Sadikin masih tinggi. Kata kunci: karakteristik; kolesteatoma; mastoiditis kronis; otitis media supuratif kronik
Occupation of The Husband is a Risk Factor for Psychological Problems Among Pregnant Immigrant Women in East Belitung, Indonesia Darmika Caroline; Dwi Izzati; Bambang Purwanto; Farida Fitriana
Jurnal Psikiatri Surabaya Vol. 14 No. 1 (2025): May
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v14i1.57382

Abstract

Introduction: According to WHO, there are 970 million people in the world who had psychological problems. The prevalence of psychological problems is highest in women (34.5%), and pregnant women who had psychological problems, especially depression, were about 10%, and 13% occurred in postpartum mothers. Psychological disorders in pregnant women might be caused by various factors, including the husband’s occupation and residency status. In order to provide the necessary care to pregnant women, it is important to know whether there is a relationship between a husband’s occupation and demographic status with maternal psychological problems. With this study, the relationship between a husband’s occupation and demographic status with psychological problems of pregnant women in the work area of Manggar Health Center, East Belitung, Indonesia can be analyzed. Methods: The study design was cross-sectional and analytic observation. The study sample consisted of 90 pregnant women (45 primiparous and 45 multiparous), who were randomly selected. The instrument used to collect data was the SRQ. Data from this study were analyzed using the chi-square test. Results: The results showed that the psychological problems in pregnant women were associated with the husband’s occupation (p = 0.018) and demographic status (p = 0.014). Conclusion: There were significant findings on the relationship between a husband’s occupation, pregnant women’s demographic status, and psychological problems.
Co-Authors AA Subiyanto Adelia Handoko Agus Sutardjo Ahmad Abdullah Ahmad Nur Huda Aldika Akbar, Muhammad Ilham Arifa Mustika Aryati Bambang Wirjatmadi Budi Prasetyo Darmika Caroline Didik Prasetyo Eko Budi Koendhori, Eko Budi Elyana Asnar Eman Sulaiman Erna Listyaningsih Esti Tantri Anandani Fitriana, Farida Gadis Meinar S Haqqelni Nur Rosyidah Hari Basuki Notobroto Hari Setiono Haryono Yuniarto Herdianty Kusuma I Gusti Bagus Wiksuana Idha Kusumawati Ilman F Martanegara Imam Susilo Indri Ngesti Rahayu Intan Herlina Irena May Rani Iwin Sumarman Izzati, Dwi Jusak Nugraha Kusnanto Kusnanto Lestari Wuryanti Lina Lasminingrum Lusi Mirnawati M. Yogiarto Made Dian Kusumawati Moh. Ali Azis Natasha Tiara Bernadette Nur Hayati Nurmala Nurmala Nurmala Nurmala Paulus Kusnanto Rahma Anindita Raihan Akbar Muhammad Refli Sudrajat Riri Handayani Rochana Ruliyandari Rohmatul Ummah Sally Mahdiani Semedi, Bambang Pujo Setiawan, Philia Shinta F Boesoirie Sony Wibisono Sugiarto Sugiarto Sumardi Maryono Suradi Maryono TATI NURHAYATI Teti Madiadipoera Tri Hardi Susanto Umi Khanifah Warigit Dri Atmoko Yoes Prijatna Dachlan Yopie Wiguna Yuan Guruh Pratama Yussy Afriani Dewi