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Toksisitas Akut dan Efek Protektif Ekstrak Etanol Schima wallichii terhadap Histopatologi Hati dan Ginjal Mencit yang Diinduksi Aloksan Risa, Tiara Nova; Rahmawati, Mutia; G R, Lutfi Khoiriyah; Kodariah, Liah; Mayuri, Nindya Sekar; Rumidatul, Alfi
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 1 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss1.2491

Abstract

Diabetes melitus (DM) merupakan penyakit metabolik kronis yang memicu komplikasi pada hati dan ginjal melalui mekanisme stres oksidatif. Tanaman Puspa (Schima wallichii (D.C) Korth) mengandung senyawa bioaktif antioksidan seperti flavonoid dan tanin yang berpotensi sebagai agen antidiabetes. Penelitian ini bertujuan mengevaluasi toksisitas akut serta efek protektif ekstrak etanol ranting S. wallichii terhadap gambaran histopalogi hati dan ginjal mencit (Mus musculus) yang diinduksi aloksan. Mencit jantan diinduksi aloksan 150 mg/kgBB secara intraperitoneal, kemudian diberikan ekstrak secara oral dengan dosis 98 mg/kgBB (P1) dan 196 mg/kgBB (P2). Parameter yang diamati meliputi berat badan, kadar glukosa darah, gejala toksisitas klinis, serta perubahan mikroskopis jaringan hati dan ginjal. Hasil menunjukkan tidak terdapat mortalitas maupun gejala toksik berat selama 14 hari pengamatan, sehingga nilai LD₅₀ semu dikategorikan praktis tidak toksik (>196 mg/kgBB). Secara histopatologis, kelompok P2 menunjukkan perbaikan signifikan pada jaringan hati (p < 0,05) yang ditandai dengan penurunan derajat degenerasi dan nekrosis. Pada ginjal terdapat tren penurunan skor kerusakan secara deskriptif, namun belum menunjukkan perbedaan bermakna secara statistik (p > 0,05). Dapat disimpulkan bahwa ekstrak ranting S. wallichii aman pada dosis uji, efektif memperbaiki kerusakan hati (hepatoprotektif), serta memiliki potensi nefroprotektif terbatas pada model mencit diabetes.
Effectiveness of Tea Twig Liquid Smoke (Camellia sinensis) as an Antiseptic against Microbes in Vivo and In Vitro Ayu Rahayu Nurul Ni'am; Aulia Nur Arrsy; Salsabila Zahroh; Feldha Fadhila; Nindya Sekar Mayuri; Alfi Rumidatul
BIOPENDIX Vol 12 No 2 (2025): Biopendix: Jurnal Biologi, Pendidikan & Terapan
Publisher : Program Studi Pendidikan Biologi FKIP Unpatti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biopendixvol12issue2page94-101

Abstract

Transmission of microorganisms that cause disease in humans occurs directly or indirectly. Prevention efforts can use antiseptics. The content of liquid smoke compounds in tea twigs has the potential to be an antiseptic. The purpose of this study was to determine the effectiveness of liquid smoke from tea twigs (Camellia sinensis) on microbial growth in vitro using the inhibition test method and in vivo swab test on the palms. In the in vitro test, the most effective results were grade 2 liquid smoke with a concentration of 75% with an inhibition zone diameter of 18.1 mm (E. coli ATCC 25922), 15.6 mm (S. aureus ATCC 25923), 32.3 mm (A. flavus ATCC 9643), 4.3 mm (C. albicans ATCC 10231). The results of the in vivo test showed effectiveness in reducing the number of bacterial colonies by an average of 88.33%, and fungal colonies by an average of 91.52%. From the entire questionnaire data, the parameters of aroma, color, dryness are in the criteria of liking and do not cause side effects on the skin. The results of the study showed that liquid smoke from tea twigs has the potential as an antiseptic.
Community-Based Pyrolysis Training and Technology Transfer for Sustainable Biomass Utilization in Metut Village Anne Hadiyane; Alfi Rumidatul; Anca Awal Sembada; Hadimanah Fikrudien Bahtiar; Atmawi Darwis; Mustika Dewi; Imra Imra
Room of Civil Society Development Vol. 5 No. 3 (2026): Room of Civil Society Development
Publisher : Lembaga Riset dan Inovasi Masyarakat Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59110/rcsd.959

Abstract

Metut Village, Mentarang Hulu District, Malinau Regency, North Kalimantan, possesses abundant woody biomass residues that remain largely underutilized despite their potential economic and environmental value. Simultaneously, local communities face challenges related to low soil fertility and limited success in agarwood (Aquilaria spp.) seed germination. This community service program aimed to introduce pyrolysis technology for converting woody biomass into biochar and liquid smoke while strengthening local capacity through training and technology transfer. By converting biomass residues that were previously left unmanaged or openly burned into valuable products, the program directly contributes to more sustainable biomass waste management at the village level. The three-day program involved 25 participants, including farmers, agarwood cultivators, village officials, women engaged in agriculture, and village youth. Activities comprised educational workshops, practical demonstrations, hands-on training, and the donation of a portable pyrolysis unit. Program effectiveness was evaluated through pre-test and post-test assessments and observation of participants’ practical performance. Results demonstrated a significant increase in knowledge, with average scores rising from 34.2% before training to 82.7% after training, reflecting a marked enhancement in community capacity to independently manage biomass resources.  All participants successfully operated the pyrolysis unit during practical sessions. A demonstration run using 12 kg of dry woody branches yielded approximately 3.2 kg of biochar and 2.1 L of liquid smoke, both promising for improving soil fertility and supporting agarwood cultivation. The donated equipment and operational manual provide a practical, replicable foundation for continued community-led biochar and liquid smoke production, supporting the long-term sustainability of biomass utilization and value-added agricultural applications.
Integrated utilization of maize residues and kernels through silage and flour production Yayat Hidayat; Anca Awal Sembada; Alfi Rumidatul; Marsinah; Tuti Juhaeti; Dedi Ruswandi
Indonesian Journal of Community Services Vol. 5 No. 1 (2026): May
Publisher : CV. Literasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47540/ijcs.v5i1.2860

Abstract

Laju Village, Langgudu District, Bima Regency, is one of the major maize-producing areas in West Nusa Tenggara, Indonesia. However, maize harvest residues, including stalks, leaves, and husks, remain largely underutilized, while dried maize kernels are generally sold without further processing, resulting in relatively low economic returns for farmers. This community service program aimed to improve the income and self-reliance of maize farmers through the implementation of two appropriate technologies: the production of silage from maize harvest residues as livestock feed and the processing of maize kernels into maize flour as a value-added product. The program was implemented through four stages: an initial survey and socialization, theoretical and hands-on training on silage and maize flour production, one month of technical mentoring, and program evaluation using pre-test and post-test assessments. The program involved members of a maize farmer group in Laju Village. The results showed a substantial improvement in participants' knowledge and technical skills, with an average knowledge increase of 89.6% following the training. Participants successfully produced high-quality silage (pH 4.2) and maize flour with a yield of 82.5%, demonstrating the feasibility of both technologies at the community level. The integration of these two technologies increased the economic value of both maize harvest residues and maize kernels while reducing dependence on conventional livestock feed and the sale of unprocessed maize. Overall, this dual-technology approach proved to be an effective community empowerment model based on local agricultural resources, contributing to improved farmer livelihoods and promoting sustainable rural economic development.
Promoting Sustainable Agriculture through Community-Based Liquid Organic Fertilizer Production from Household Organic Waste in Metut Village, North Kalimantan Alfi Rumidatul; atmawi darwis; Anca Awal Sembada; Anne hadiyane; Mustika dewi; Imra Imra; Mustika Dewi
International Journal of Community Service (IJCS) Vol. 5 No. 2 (2026): July-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijcs.v5i2.1999

Abstract

The accumulation of unmanaged household organic waste remains a persistent environmental challenge in rural areas, including Metut Village, Mentarang Hulu District, North Kalimantan, Indonesia, where organic waste is commonly burned or indiscriminately discarded. At the same time, local farmers continue to depend on relatively expensive chemical fertilizers. This community service program aimed to improve residents’ knowledge and practical skills in converting household organic waste into liquid organic fertilizer (LOF) as an affordable and environmentally friendly alternative for sustainable agriculture. The program employed a combination of community education and hands-on training implemented through four stages: socialization and educational counseling, training and demonstration, supervised independent practice, and evaluation using pre-test and post-test assessments. A total of 28 participants, consisting of housewives, farmer group members, and village youth, were involved in the program. The results demonstrated a substantial increase in participants’ knowledge, with average scores improving from 46.4 in the pre-test to 86.1 in the post-test. Participants successfully produced liquid organic fertilizer independently using kitchen waste fermented with a bioactivator for 14–21 days and subsequently applied the product to home garden crops. The program contributed to reducing household organic waste generation, lowering fertilizer expenditures, and promoting environmentally sustainable agricultural practices. These findings indicate that liquid organic fertilizer training is an effective approach for community empowerment and sustainable waste management in rural communities.
Community-Based Pyrolysis Training and Technology Transfer for Sustainable Biomass Utilization in Metut Village Anne Hadiyane; Alfi Rumidatul; Anca Awal Sembada; Hadimanah Fikrudien Bahtiar; Atmawi Darwis; Mustika Dewi; Imra Imra
Room of Civil Society Development Vol. 5 No. 3 (2026): Room of Civil Society Development
Publisher : Lembaga Riset dan Inovasi Masyarakat Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59110/rcsd.959

Abstract

Metut Village, Mentarang Hulu District, Malinau Regency, North Kalimantan, possesses abundant woody biomass residues that remain largely underutilized despite their potential economic and environmental value. Simultaneously, local communities face challenges related to low soil fertility and limited success in agarwood (Aquilaria spp.) seed germination. This community service program aimed to introduce pyrolysis technology for converting woody biomass into biochar and liquid smoke while strengthening local capacity through training and technology transfer. By converting biomass residues that were previously left unmanaged or openly burned into valuable products, the program directly contributes to more sustainable biomass waste management at the village level. The three-day program involved 25 participants, including farmers, agarwood cultivators, village officials, women engaged in agriculture, and village youth. Activities comprised educational workshops, practical demonstrations, hands-on training, and the donation of a portable pyrolysis unit. Program effectiveness was evaluated through pre-test and post-test assessments and observation of participants’ practical performance. Results demonstrated a significant increase in knowledge, with average scores rising from 34.2% before training to 82.7% after training, reflecting a marked enhancement in community capacity to independently manage biomass resources.  All participants successfully operated the pyrolysis unit during practical sessions. A demonstration run using 12 kg of dry woody branches yielded approximately 3.2 kg of biochar and 2.1 L of liquid smoke, both promising for improving soil fertility and supporting agarwood cultivation. The donated equipment and operational manual provide a practical, replicable foundation for continued community-led biochar and liquid smoke production, supporting the long-term sustainability of biomass utilization and value-added agricultural applications.
Co-Authors Adzra, Fa’izzah Nur Ahmad Sodikin Alamsyah, Muhamad Thamrin Alfani, Fhadliana Alifah, Aqil Anca Awal Sembada Anca Awal Sembada Anca Awal Sembada Anisa, Divia Anzar irawan saepul Armela, Diana Rizki Atmawi DARWIS atmawi darwis Atmawi Darwis Aulia Nur Arrsy Ayu Rahayu Nurul Ni'am Budianti, Noviana Bunga Wahyuniah Dayanti, Nyimas Dedi Ruswandi Dedi Ruswandi Deni Zamaludin Dewi Larasati Dheanna P.S Rachmawati Dilla Saphira Fitriani Eki Andini Fadhila, Feldha Fadilah, Tyas I. Fauziah, Anti Zulfitri Feldha Fadhila Feldha Fadhila Feldha Fadhila Firdausia, Ajeung Dewi Fitriani, Dilla Saphira G R, Lutfi Khoiriyah Gustan Pari H.Y, Siti Yesi Hadimanah Fikrudien Bahtiar Hadiyane, Anne Hurient Sani Nabillah Iman, Moch Fajar Anugrah Imra Imra imra imra Ira Puspa Dewi Juniar, Fadia Rahma Khairin Rabbani Khusna, Wasiyah Kodariah, Liah Kusuma Handayani, Kusuma Liah Kodariah Luluil Fajry Thasya Sonya Lussy Carnellya Fitri Marsinah Marsinah Maryana, Yayan Mawangi, Neng W. L. Mayuri, Nindya S. Mayuri, Nindya Sekar Mustika Dewi Mustika dewi Mustika Dewi Muzjahidah, Nelly Siti Nabila, Hasna Putri Nabillah, Hurient Sani Nainggolan, Ribka Debora Navila, Aviva Nelly Siti Muzjahidah Nindya Sekar Mayuri Nindya Sekar Mayuri Nindya Sekar Mayuri Nisa Febrianti Noor Rahmawati Nurhasanah, Ai Sri Nurjaman, Deni Nurjana, Siti Nursifah, Devi Popy Hasanah Popy Listiani Pragita, Anisa Sri Putri Vaolina Qomariah, Annisa Nur Rahayu, Amalia Rahmawati, Mutia Rina Marlina Rini Mastuti Risa, Tiara Nova Riska Amelia Rohmah, Fitriani Nurhidayati Salsabila Zahroh Sandy, Pracilia S. Saptadi DARMAWAN Sembada, Anca Awal Setiawati, Yeyet Shafa, Dheanna Putri Shenny Fitriani Sindi Pitrianingsih Sonya, Luluil Fajry Thasya Sopandie Sunarya Sugara, Yuliannisa Sulistyawati, Annisa Lathifah Tati Karliati Tri Rahayu, Nunik Tuti Juhaeti Vaolina, Putri Wahyuniah, Bunga Wasiyah Khusna Yani Suryani Yayan Maryana Yayan Maryana Yayan Maryana Yayat Hidayat Yayat Hidayat Yayat Hidayat Yuliani, Septa Zaenudin Arif, Jihan Ahmad Zamaludin, Deni