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Histopathological Overview of Kidney and Liver Female White Rat Administered (Ananas comosus var. microstachys L.) Extract as Herbal Plant for Dysmenorrhea Fitmawati, Fitmawati; Saputra, Agus; Teruna, Hilwan Yuda; Juliantari, Erwina
Al-Kauniyah: Jurnal Biologi Vol. 17 No. 2 (2024): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v17i2.31421

Abstract

Abstract Dysmenorrhea is an important clinical as well as social problem affecting more than 50% of menstruating women. Nanas bongsai (Ananas comosus var. microstachys L.) is commonly used as a medical plant, which local people believe of Riau Province Indonesia, as medicine to reduce pain while the menstruation period (dysmenorrhea). This study was aim to find histopathologic changes in the kidney and liver after being treated with nanas bongsai extract in the female white rat.  Design experimental of this research is complete randomized design with 5 treatments. Each treatment was composed of two control (zero control given with water, positive control given with mefenamic acid) and nanas bongsai extract with 3 different dosage serials. Histology preparations were made by paraffin method and Hematoxylin-Eosin staining. The results showed that given nanas bongsai extract with three serial dosages towards the kidney show a picnosis in the nucleus. However, this damage did not affect the glomerulus structure. While observation towards the liver shows some injury, namely hydropic degeneration, lipid degeneration, and necrosis. Both of these damaged less than 25%. As a result, this percentage did not affect the structure of the kidney and liver. The results of this study indicate that there is no damage to the kidneys and liver due to the use of nanas bongsai so it is safe to use in herbal medicine and can be developed as a dysmenorrhea drug.AbstrakDismenore merupakan masalah klinis dan sosial yang penting yang memengaruhi lebih dari 50% wanita menstruasi. Nanas bongsai (Ananas comosus var. microstachys L.) dipercayai oleh masyarakat Desa Muara lembu, Kabupaten Kuantan Singingi, Provinsi Riau sebagai obat untuk mengurangi nyeri saat haid (dismenore). Penelitian ini bertujuan untuk mengetahui perubahan histopatologi pada ginjal dan hati setelah diberi perlakuan ekstrak nanas bongsai pada tikus putih betina. Rancangan percobaan yang digunakan adalah rancangan acak lengkap dengan 5 perlakuan. Masing-masing perlakuan terdiri dari dua kontrol dan ekstrak nanas bongsai dengan 3 seri dosis yang berbeda. Preparat histologi dibuat dengan metode parafin dan pewarnaan Hematoxylin-Eosin. Hasil penelitian menunjukkan bahwa pemberian ekstrak nanas bongsai dengan dosis tiga seri terhadap ginjal menunjukkan picnosis pada nukleus. Namun, kerusakan ini tidak memengaruhi struktur glomerulus. Sedangkan pengamatan terhadap hati menunjukkan beberapa cedera, yaitu degenerasi hidropik, degenerasi lipid, dan nekrosis. Keduanya rusak kurang dari 25%. Akibatnya, persentase ini tidak memengaruhi struktur ginjal dan hati. Hasil penelitian ini menunjukkan bahwa tidak ada kerusakan pada ginjal dan hati akibat penggunaan Nanas bongsai sehingga aman digunakan dalam pengobatan herbal dan dapat dikembangkan sebagai obat dismenore.
Ethnobotanical Study of Medicina Ethnobotanical Study of Medicinal Plants Used by the Indigenous Community of Mbaham in Karas District Fakfak Regency West Papua Ubay, Santi; Fitmawati, Fitmawati
EKOTONIA: Jurnal Penelitian Biologi, Botani, Zoologi, dan Mikrobiologi Vol 9 No 1 (2024): Ekotonia: Jurnal Penelitian Biologi, Botani, Zoologi dan Mikrobiologi
Publisher : Department of Biology, Faculty of Agriculture, Fisheries and Biology, University of Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/ekotonia.v9i1.5046

Abstract

Medicinal plants are the main element in the local medicine system in Karas District, Fakfak Regency. This is closely related to the culture and traditional knowledge of the community. This study aims to identify the species of medicinal plants used by Traditional Medicine Practitioners (TMP) An ethnobotanical survey was conducted to collect information from Traditional Medicine Practitioners from January to February 2023. The research method used by interviewing six informants who had information about the use of medicinal plants. The results showed that there were 57 species of medicinal plants from 35 families that had been used to treat 39 types of diseases. The most used plan part by TMP is leaf (19%) Boiling is the most commonly used processing method. Medicinal plants with the highest use value used by TMP are Andrographis paniculata, Annona muricata, Momordica charantia, Terminalia catappa, Jatropha curcas, Spatholobus littoralis, Piper betle, Cymbopogon citratus, Citrus aurantifolia, Curcuma longa, dan Zingiber officinale with a UV value = 1.00. The category of circulatory system is the most treated disease category with an ICF value of 0.8. Medicinal plants with the highest percentage accuracy value are Andrographis paniculata, Annona muricata, Momordica charantia, Terminalia catappa, Jatropha curcas, Spatholobus littoralis, Piper betle, Cymbopogon citratus, Citrus aurantifolia, Curcuma longa, dan Zingiber officinale with FL = 100%. Keywords: Ethnobotany, Karas District, Fakfak, Traditional Medicine Practitioners (TMP), Medicinal Plant.
Aplikasi Bioteknologi untuk Pengolahan Tandan Kelapa Sawit dan Sampah Organik Menuju Kemandirian Pupuk di Desa Kampung Tengah, Siak Isda, Mayta Novaliza; Fitmawati; Sujarwati; Titrawani; Lestari, Wahyu; Afrilliani, Aneka; Yovita, Cici; Stefani, Dea; Indriani, Desi; Sari, Dwi Retno; Sari, Fajrika; Zulva, Naya Septia; Fahira, Nidia; Ramadhan, Wahyu; Sirait, Yudhistio Artia Perdamaian
KALANDRA Jurnal Pengabdian Kepada Masyarakat Vol 3 No 6 (2024): November
Publisher : Yayasan Kajian Riset Dan Pengembangan Radisi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55266/jurnalkalandra.v3i6.452

Abstract

Empty oil palm bunches (OPEFB) contain important nutrients such as nitrogen (N), phosphorus (P), potassium (K), and micronutrients such as boron (B), copper (Cu), zinc (Zn), iron (Fe), and manganese (Mn). These nutrients can be released into the soil and are available for plant growth with empty oil palm bunches. Composting is a natural recycling method and returns organic matter to the biological cycle. OPEFB as an organic fertilizer has great potential to help increase soil fertility and productivity. Utilization of organic waste in the form of liquid compost can be done using a composter. Processing waste into compost can have quite high economic value. This community service activity received a positive response from the Kampung Tengah village community because it increased knowledge related to the processing of OPEFB waste and also organic waste so that it becomes useful and economically valuable compost.
MANAJEMEN BAITUL MAL PADA MASA KHALIFAH UMAR BIN KHATHAB R.A: SEBUAH TINJAUAN SEJARAH Fitmawati, Fitmawati
Jurnal Ilmiah Syi'ar Vol 19, No 1 (2019): June 2019
Publisher : UIN Fatmawati Sukarno Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29300/syiar.v19i1.10533

Abstract

Umar bin Khathab menjadi khalifah sekitar 10 tahun. Dia sangat dikenal sebagai kebijakan ekspansinya. Dia memperkenalkan sistem administrasi pemerintahan dengan membagi wilayahnya dan membangun Baitul mal menjadi lembaga independen. Kebijakan-kebijakan perluasan itu telah mencapai tujuan dengan sukses, sehingga pendapatan orang-orang Baitul mal itu terlalu banyak. Kemudian, khalifah Umar mengaturnya melalui akumulasi dan emisi dengan membentuk Diwan. Dia telah menerapkan konsep manajemen Islam jauh sebelum manajemen weit exisheted. Konsentrasi Umar memberikan preferensi pada cara yang terkait dengan nilai iman dan kebenaran. Dia juga menerapkan konsep Syura pada cara dan aktivitas manajemen, terutama yang terkait dengan penentuan keputusan. Membagi daerah pemerintahan dan Amir dan Madinah sebagai pusat pemerintahan dan Baitu mal sebagai lembaga independen yang keluar dari campur tangan pemerintah menjadi kontribusi Umar.
Ethnopharmacological Insights into Asteraceae: Traditional Medicine and Therapeutic Potential in the Gayo Highlands, Bener Meriah Regency Puspa, Vivera Ruselli; Zumaidar; Nurdin; Fitmawati; Fathiya, Nir
Biotik Vol 14 No 1 (2026): JURNAL BIOTIK
Publisher : Universitas Islam Negeri Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/biotik.v14i1.34060

Abstract

The Gayo Highlands communities use Asteraceae species in traditional medicine to treat various ailments. This study aimed to document the ethnopharmacological use of Asteraceae and assess community knowledge regarding their medicinal applications. Data were collected from 48 respondents across eight sub-districts using purposive sampling and structured questionnaires. The study identified 10 Asteraceae species used to treat 10 diseases, including diabetes mellitus (DM), cancer, hypertension, liver disorders, common cold, bloating, cough, fever, toothache, and skin itching. Leaves were the most frequently used plant organ (95.96%), mainly from wild plants growing near home yards or abandoned land. Approximately 81.25% of respondents reported using Asteraceae to manage DM. Standard preparation methods included boiling and pounding, with the leaves of Erigeron sumatrensis Retz being the most widely recognized and utilized for the treatment of DM and cancer. The community’s preference for these plants is attributed to their availability, perceived safety, and efficacy. This study highlights the significant ethnopharmacological potential of Asteraceae in the Gayo Highlands and provides a basis for further pharmacological investigations, particularly on E. sumatrensis. Keyword: Asteraceae; traditional medicine; ethnopharmacology; Gayo Highlands; Erigeron sumatrensis
Co-Authors ', Trina , WULANDARI D , ZULHENDRA A.A. Ketut Agung Cahyawan W Afrilliani, Aneka Agustin, Hawa Merdika Andriko, Andriko Asih Rahayu Ajeng Agesti DAYANA, SABELLA Delita Zul Desi Indriani, Desi Dewi Indriyani Roslim Dewi, Awal Prichatin Kusumo Dimas Pramita Nugraha Dini Palupi Putri, Dini Palupi Dwi Retno Sari, Dwi Retno Erwina Juliantari ERWINA JULIANTARI, ERWINA Fahira, Nidia Fajrin, Joane Fathurrahman Fathurrahman Fitra Suzanti Fitri, Febrian Lailatul Hakim, Zalika Auliasari Hamidi, Yulis Hari KAPLI Haris Gunawan HAYATI, IBNA Herman - Herman Herman Hilwan Yuda Teruna Isnaini Isnaini Khaidir Anuar Khasana, Ulfah Kholifah, Sri Nur Kurnia, Hersan Bayu Kusumo, Awal Prichatin M. Yogi Riyantama Isjoni Maemonah, Maemonah Maya Sari Mayta Novaliza Isda Mayta Novaliza Isda Melita Sari, Sindi NAPSIYAH, LUTHFI KHOTUN Nery Sofiyanti Ninik Nihayatul Wahibah Nir Fathiya Nur Anisa Nurdin Nurfadhila, Amanda Oktapiyani, Lia Okyarni Nuzila Paramita, Desi Permadi, Gelong PRANATA, SYAFRONI Pranata, Syafroni Purwoko, Agus Puspa, Vivera Ruselli Putri Rahma Dianti Rafidah, Nurul Rodesia Mustika Roza Roza Elvyra Salpa Hartanto Saputra, Agus Saputra, Agus Saputra, Agus Sari, Fajrika Sinaga, Adinda Patricia Adelina Sinaga, Patar Sirait, Yudhistio Artia Perdamaian Siska Sri Wahyuni, Siska Sri Siti Fatonah Stefani, Dea Suhendra, Meyla Sujarwati Susi Supriani Thobib Hasan Al Yamini Titrawani Titrawani Titrawani Titrawani Titrawani, Titrawani Ubay, Santi Via Andani Wahyu Lestari Wahyu Ramadhan Welly Safitri Welly Safitri, Welly Winata, Dhaniel Ridho Yeni Rahayu Yohanes Yohanes Yovita, Cici Yulianti, Githa Adennita Yulisa Resti Irawan YULMINARTI, YULMINARTI Yusfiati, Yusfiati YUSNA, MACHFIRA Zulva, Naya Septia Zumaidar Zutia Wulandari