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Journal : Paediatrica Indonesiana

Nasopharyngeal bacterial carriage and antimicrobial resistance in underfive children with community acquired pneumonia Cissy B. Kartasasmita; Heda Melinda Duddy; Sunaryati Sudigdoadi; Dwi Agustian; Ina Setiowati; Tri Hanggono Ahmad; Ramdan Panigoro
Paediatrica Indonesiana Vol 41 No 11-12 (2001): November 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.6.2001.292-5

Abstract

Lung puncture is the best way to determine the etiology of pneumonia since it yields the highest rate of positive cultures. However, this procedure is difficult, especially for a study in the community. According to WHO, isolates to be tested for antimicrobial resistance in the community should be obtained from nasopharyngeal (NP) swabs. Previous studies support the use of NP isolates to determine antimicrobial resistance patterns of isolates from children with pneumonia. The aim of our study was to know the bacterial patterns of the nasopharynx in underfive children with community acquired pneumonia and their antimicrobial resistance. The study was carried out in 4 Primary Health Clinics in Majalaya sub-district, Bandung, Indonesia. All underfives with cough or difficult breathing and classified as having non-severe pneumonia (WHO guidelines), were included in the study. Nasopharyngeal swabs (CDC/WHO Manual) were obtained by the doctor, the swabs were placed in Amies transport medium and stored in a sterile jar before taken to the laboratory in the same day. All children were treated with co-trimoxazole. During the nine month study, 698 children with clinical signs of non-severe pneumonia were enrolled. About 25% of the nasopharyngeal specimens yielded bacterial isolates; the two most frequently found were S. pneumoniae and S. epidermidis. The antimicrobial resistance test to co-trimoxazole showed 48.2% S. pneumoniae strain had full resistance and 32.7% showed intermediate resistance to co-trimoxazole. This result is almost similar to other studies from Asian countries. It seems that H. influenzae is not a problem in the study area; however, further studies are needed.
Co-Authors Adi Imam Cahyadi Afiatin Afiatin Andi Hiroyuki Anton Widodo Ardini Raksanegara Ardini S. Raksanagara, Ardini S. Arsesiani, Angga Arya, Insi Farisya Deasy Asep K. Supriatna Asep Sofyan B. Kartasasmita, Cissy Bachti Alisjahbana Budi Sujatmiko Chrysanti Murad, Chrysanti Cica Lavemita Cissy B. Kartasasmita Cissy B. Kartasasmita Dani Ferdian Dany Hilmanto Dhanasari Vidiawati Dida Akhmad Gurnida Didah Edward Trihadi Fauziah, Nisa Fedri Ruluwedrata Rinawan Firman Fuad Wirakusumah Gaga Irawan Nugraha Hadi Susiarno Hadisoemarto, Panji Hadyana Sukandar Heda M. Duddy Heda Melinda Duddy Helmiyetti Helmiyetti Helni Mariani Heni Djuhaeni Ilham Muthahhari Ina Setiowati Ina Setiowati Iqbal Ainnun Azis Kurnia Wahyudi Kusnandi Rusmil Kuswandewi Mutyara Lia Faridah M. Uyeki, Timothy Maringan Diapari L.T Moeliono, Marina Annette Moeliono, Marina Annette Mohamad Irfan, Mohamad Muchamad Rizqy Nugraha Namira Oktaviani Suwarna Natalia, Lensi Ndii, Meksianis Z Nia Fararid Askar Ningsih, Fitriani Nita Arisanti Nita Arisanti Nita Arisanti obin sarwita Pandu Riono Panji Hadisoemarto Putria Carolina, Putria Ramdan Panigoro Rochmah Supriati Rully Marsis Amirullah Roesli Salsabila, Susan Salsabila, Susan Santanu, Ayu Mutiara Sastradimadja, Sunaryo Barki Sastradimadja, Sunaryo Barki Septian Mugi Rahayu, Septian Mugi Shelly Iskandar Simoes, Eric AF. Siti Santy Sianipar, Siti Santy Sri Yusnita Irda Sari, Sri Yusnita Irda Suhin, Hermanto Sunaryati Sudigdoadi Sunaryati Sudigdoadi Sunjaya, Deni K. Supriatna, Asep K. Tessa Melinda Agatta Tetty Yuniati Titik Respati Tri H. Ahmad Tri Hanggono Achmad Tri Hanggono Ahmad Ulfi Ainun Hanifah Ulfi Ainun Hanifah, Ulfi Ainun Uun Sumardi, Uun Valiant Yuvi Syahreza Wulan Mayasari Zulmansyah , Zulmansyah