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Identifikasi Kandungan Senyawa Aktif dan Penentuan Massa Jenis Ekstrak Etanol Daun Jambu Air (Syzygium aqueum) Naufal, Muhammad Ariq; Susianti; Daulay, Suryani Agustina; Carolia, Novita
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1320

Abstract

Water apple (Syzygium aqueum) is a plant widely utilized by publics for both consumption and medicinal purposes. Traditionally, it is used as an alternative treatment for diarrhea, headaches, and cough. The method to maximize the potential of water apple leaves is by extracting the active compounds in it. These extracts have potential as antioxidants, anti-inflammatory, anti-cholesterol, antidiabetics, and antidiarrheal agents. Previous studies have shown that water apple leaves contain various active compounds such as alkaloids, flavonoids, terpenoids, saponins, and phenolics. This research aimed to analyze the active compounds and determine the density of the water apple leaf extract. The study was conducted as a laboratory-based experimental research at the Botany Laboratory, FMIPA University of Lampung. The method employed was maceration of water apple leaves using 96% ethanol as a solvent, followed by qualitative phytochemical tests and density determination. Qualitative tests conducted included assessments for flavonoids, terpenoids, tannins, saponins, phenolics, alkaloids, and steroids. The density of the extract was determined by measuring the mass of the extract using an analytical balance and dividing it by its volume. The results showed that maceration using 96% ethanol yielded 110.62 grams of extract with a yield percentage of 11.062%. Phytochemical tests revealed the ethanol extract contained flavonoids, phenolics, tannins, saponins, alkaloids, and steroids. The density of the ethanol extract was calculated to be 0.9209 g/mL.
Profile of Melanoma and Non-Melanoma Skin Cancer based on Histopathology Results Zulfa, Fathimah; Windarti, Indri; Sutarto; Carolia, Novita
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1342

Abstract

Skin cancer is an abnormal condition in the structure of the skin that arises because the skin loses the ability to regenerate periodically. Skin cancer is high risk in people who live in tropical countries such as Indonesia. All provinces in Indonesia receive evenly distributed sunlight including Lampung province. Lampung Province is an agricultural province with the dominance of the population working in agriculture and marine sectors. Agriculture and marine sectors workers get continuous and long-term exposure to UV rays so that they are at high risk of skin disorders, one of them is skin cancer. This study was conducted in August-December 2024 in the medical record from Dr. H. Abdul Moeloek Hospital Bandar Lampung. This study was observational and was conducted by collecting data and univariate analysis on medical record data of skin cancer patients including the type of skin cancer, age, gender ], and location of tumor growth of skin cancer patients. The results showed that the most common type of skin cancer diagnosed at Dr. H. Abdul Moeloek Bandar Lampung Hospital in the 2019-2024 period was non-melanoma skin cancer (squamous cell carcinoma followed by basal cell carcinoma). The most common age of skin cancer patients is ≥40 years old, female and the location of tumor growth is mostly in the head and neck area.
Model Gerabah (Gerakan Kontrol Bahaya Diabetes Dan Hipertensi) Sebagai Upaya Pencegahan dan Penanggulangan Penyakit Kronis Angraini, Dian Isti; Febriani, Wiwi; Carolia, Novita; Mayasari, Diana; Anggraeni, Liza; Fitri, Dilla Syahra Noor; Fathaniah, Widya
Reswara: Jurnal Pengabdian Kepada Masyarakat Vol 5, No 2 (2024)
Publisher : Universitas Dharmawangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46576/rjpkm.v5i2.4322

Abstract

Model GERABAH (Gerakan Pengendalian Bahaya Diabetes dan Hipertensi) telah secara khusus dibuat dan diadaptasi untuk inisiatif pemberdayaan pendidikan dan masyarakat yang bertujuan mengurangi penyakit kronis seperti diabetes mellitus (DM) dan hipertensi. Model ini dirancang dengan teknik edukasi dan pemeriksaan kesehatan. Kegiatan ini bertujuan untuk meningkatkan pemahaman dan keterampilan masyarakat dalam mencegah dan menanggulangi penyakit kronis (DM dan Hipertensi). Metode yang akan dilakukan adalah dengan memberikan penyuluhan, pemeriksaan kesehatan (gula darah sewaktu dan tekanan darah), serta konseling. Kegiatan Model GERABAH ini dilaksanakan di desa Merak Batin Kecamatan Natar Kabupaten Lampung Selatan pada tanggal 29 November 2023. Peserta kegiatan ini adalah 65 orang pralansia dan lansia di desa Merak Batin. Hasil evaluasi pelaksanaan pengabdian menunjukkan bahwa sebanyak 83,1% peserta mengalami peningkatan pemahaman menjadi baik, sedangkan sebanyak 12,3% peserta memiliki pemahaman yang cukup mengenai pencegahan dan penanggulangan penyakit kronis (DM dan Hipertensi) baik secara medikamentosa ataupun non medikamentosa. Rata-rata pemahaman responden meningkat yang sebelumnya 55,1 pada pretest menjadi 81,5 pada posttest. Hasil analisis statistik menggunakan uji Wilcoxon menunjukkan bahwa terdapat perbedaan rata-rata yang bermakna secara statistik pada nilai pretest dan postest peserta mengenai pencegahan dan penanggulangan penyakit kronis (DM dan Hipertensi) (p=0,000). Hasil pemeriksaan gula darah sewaktu dan tekanan darah didapatkan bahwa peserta yang memiliki kadar glukosa darah tinggi 47,7% dan memiliki tekanan darah tinggi sebanyak 89,2%. Model GERABAH ini terbukti efektif dalam meningkatkan pengetahuan dan kemampuan Masyarakat dalam mencegah dan menanggulangi penyakit kronis (DM dan Hipertensi)
Fotokimia dan Farmakologi Daun Alpukat (Persea americana mill.) pada Aktivitas Antihipertensi Husnandari, Aqila; Carolia, Novita; Putri, Giska Tri; Rahmanisa, Soraya
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1246

Abstract

Hypertension is the number one generative disease in the world that has blood pressure of more than 140/90 mmHg. Hypertension without therapy will become chronic and complicated. Therapy carried out for a long period of time causes a fairly high risk factor so that herbal therapy becomes an alternative. This literature review aims to determine the photochemistry and pharmacology of avocado leaves (Persea americana mill.) On antihypertensive activity. Photochemistry contained in avocado leaves can lower blood pressure in the form of flavonoids, saponins, tannins, alkaloids, steroids, and terpenoids. The method used is to review journal articles that have been published in Google Scholar and Pubmed. Using keywords such as "photochemistry, pharmacology, avocado leaves, and antihypertensive activity" 231 scientific articles and journals were obtained. This review article uses 10 selected scientific articles and journals. Experimental studies show that there are pharmacological functions that fight hypertension, which means that they can lower blood pressure.
Keberadaan Bakteri Coliform dan Escherichia coli dalam Sumber Air Bersih Sebagai Penyebab Diare pada Rumah Tangga: Literature Review Fathia, Nauriel; Utama, Winda Trijayanthi; Marcellia, Selvi; Carolia, Novita
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1293

Abstract

Water is an essential necessity for humans on Earth. Its role is crucial for daily activities, including household needs, industry, offices, and food production. In Indonesia, each person is estimated to require approximately 30–60 liters of water per day, whereas in developed countries, the demand per person ranges between 60–120 liters per day. The feasibility of water usage is regulated based on quality characteristics, referred to as water quality. One of the key indicators related to household water quality is biological parameters, particularly concerning the presence of coliform bacteria and Escherichia coli. These bacteria have a fecal-oral entry route, meaning that if consumed in excessive amounts, they can cause gastrointestinal diseases, primarily diarrhea. This study aims to examine the impact of coliform and Escherichia coli contamination in household water sources, leading to diarrhea cases. The research method used is a literature review and analysis. The findings indicate that the presence of Escherichia coli in household water sources, especially in areas with poor sanitation, poses a high health risk, particularly increasing the likelihood of diarrhea. Several factors contribute to this contamination, including the proximity of wells to pollution sources, inadequate waste management, and improper well construction that does not meet safety standards. These conditions suggest that environmental sanitation and the distance between water sources and potential contaminants play a significant role in water quality and public health. Through this study, it is expected that the community will be more aware of the importance of maintaining clean water used for household needs to prevent diarrhea-related diseases.
IMPROVING KNOWLEDGE AND SKILLS ON MEDICAL NUTRITION THERAPY IN TYPE 2 DIABETES MELLITUS PATIENTS IN AGRICULTURAL COMMUNITIES Angraini, Dian Isti; Carolia, Novita; Mayasari, Diana; Imantika, Efriyan
Community Development Journal Vol 9 No 1 (2025): Community Development Journal
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/cdj.v9i1.7090

Abstract

The prevalence of type 2 Diabetes Mellitus continues to increase, including in agricultural communities (farmers). Low treatment compliance can result in increased complications, morbidity and mortality. Medical nutrition therapy is one of the recommended diabetes control measures. Lack of education, understanding of diet, and family support causes many DM patients to not comply with diet therapy recommendations. The purpose of this activity is to provide health education (health promotion) regarding medical nutrition therapy for DM treatment to type 2 DM patients in the agricultural community, conduct a meal planning simulation (DM diet) that is in accordance with the condition of type 2 DM patients, and increase the knowledge and skills of type 2 DM patients in medical nutrition therapy. The method that will be used is health education (promotion) on medical nutrition therapy for type 2 DM patients and a meal planning simulation regarding the DM diet. The results of the evaluation of the implementation of community service showed that there was an increase in the knowledge of participants by 90% to a good knowledge, 10% of participants had a moderate knowledge, and no participants had a poor knowledge of the definition of DM, symptoms and signs, risk factors, treatment/therapy, disease prevention, prevention of complications, medical nutrition therapy/DM diet, exchange foods, recommended and not recommended foods for DM patients and myths and facts about type 2 DM. The average pre-test result was 52.5 and increased in the post-test result of 82. Based on the analysis using the Wilcoxon test, it was found that there was a statistically significant difference in the pre-test and post-test values ​​of community service participants (p = 0.000). The activity of increasing knowledge and skills regarding medical nutrition therapy for type 2 diabetes mellitus patients in the agricultural community is a way to improve the ability of the community, especially type 2 DM patients, in managing medical nutrition therapy for type 2 DM, as an effort to prevent worsening and complications. The activity of increasing understanding and skills regarding medical nutrition therapy for type 2 diabetes mellitus patients in the agricultural community has proven effective.
Hunungan Pengetahuan dan Tingkar Pendidikan dengan Perilaku Pencegahan Demam Berdarah di Desa Muara Gading Mas Ningrum, Adenias Lutfia; Rosa, Emantis; Carolia, Novita; Karyus, Aila
Jurnal Dunia Kesmas Vol 13, No 2 (2024): Volume 13 Nomor 2
Publisher : Persatuan Dosen Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jdk.v13i2.15854

Abstract

Demam berdarah dengue merupan penyakit infeksi disebabkan oleh virus dengue dengan vektor perantara nyamuk Aedes aegypti. Saat ini jumlah kasus DBD mencapai 71.633, salah satu kasus tertinggi yaitu terjadi di provinsi lampung dengan IR 64,4/100.000 penduduk, CFR 0,3 %. Seiring meningkatnya DBD pemerintah memberikan kebijaka terhadap pencegahan DBD dengan cara melakukan PSN 3M Plus. Tujuan dari penelitian ini yaitu untuk mengetahui hubungan pengetahuan dan tingkat pendidikan masyarakat dengan perilaku pencegahan penyakit DBD di desa muara gading mas kecamatan labuhan maringgai kabupaten lampung timur. Metode yang digunakan observasional pendekatan cross sectional, dibutuhkan 94 sampel, pemilihan sampe berdasarkan kriteria insklusi dan eksklusi lalu menggunakan teknik sample random sampling, data diambil menggunakan kuesioner pengetahuan dan perilaku pencegahan, kemudian dioleh dan dianalisis menggunakan analisis univariat dan bivariat yaitu uji chii-square. Hasil perilaku pencegahan dengan hubungan pengetahuan didapatkan p-value 0,001 dan dengan hubungan tingkat pendidikan masyarakat didapatkan p-value 0,001. Hasil tersebut menyatakan bahwa terdapat hubungan yang signifikan antara pengetahuan dan tingkat pendidikan masyarakat dengan perilaku pencegahan DBD di desa muara gading mas kecamatan labuhan maringgai kabupaten lampung timur. Kata kunci: pengetahuan, tingkat pendidikan, perilaku pencegahan DBD.
Monitoring The Growth And Development Of Toddler During The Covid 19 Pandemic Using The Rajabalita Application And KIA Tri Novadela, Nora Isa; Carolia, Novita; Rasyid, Risneni; Nurchairina, Nurchairina
JKM (Jurnal Kebidanan Malahayati) Vol 9, No 4 (2023): Volume 9 No. 4 Oktober 2023
Publisher : Program Studi Kebidanan Fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkm.v9i4.12252

Abstract

Latar Belakang Pemerintah dalam pemantauan tumbuh kembang balita, salah satunya menggunakan program penimbangan berat badan dan pengukuran tinggi badan Balita di Posyandu yang dituangkan atau didokumentasikan kedalam buku KIA. Penggunaan Buku KIA sangat bermanfaat bagi orang tua dalam memantau pertumbuhan dan perkembangan Balita. Peneliti membandingkan efektifitas dari penggunaan aplikasi rajabalita dengan penggunaan buku KIA terhadap pemantauan tumbuh kembang pada balita.Tujuan penelitian ini adalah untuk mengetahui perbandingan pemantauan tumbuh kembang Balita menggunakan Aplikasi Rajabalita dan Buku KIAMetode penelitian ini menggunakan Desain penelitian true-eksperimen, dua kelompok dengan desain pra dan post tes. Teknik pengambilan sampel adalah Simple Random Sampling dengan jumlah sampel sebanyak 100  orang. Analisa data secara univariat dan analisa bivariat dengan T-Test Dependen dan T-Test IndependentHasil penelitian yang diperoleh dari seluruh responden, 100 orang balita (100%), seluruhnya dalam status perkembangan normal. Dan diketahui bahwa persentase terbesar pada kualitas buku KIA yaitu pada tingkat relevansi informasi, yaitu sebesar 64 %, sedangkan persentase terbesar pada kualitas aplikasi yaitu pada kualitas ketepatan waktu informasi, yaitu 80%.Kesimpulannya dapat diketahui bahwa penggunaan Aplikasi Rajabalita sangat bermanfaat dan efektif dalam memantau tumbuh kembang balita pada masa pandemicSaran Peneliti menyarankan untuk terus melakukan kegiatan yang melibatkan masyarakat dalam hal pencegahan stunting dengan metode yang terus berinovasi, dan menggunakan media yang bermacam macam, sehingga akan lebih banyak masyarakat yang tertarik  untuk melibatkan diri, dan pada akhirnya dapat menimbulkan kesadaran dan kemandirian masyarakat Keyword : Balita; Aplikasi; Rajabalita; KIA;Tumbuh kembang ABSTRACT Background: The government in monitoring the growth and development of toddlers, one of which is using a program for weighing and measuring the height of toddlers at Posyandu which is outlined or documented in the KIA book. Using the KIA Book is very useful for parents in monitoring the growth and development of toddlers. Researchers compared the effectiveness of using the Rajabalita application with using the KIA book in monitoring growth and development in toddlers.The aim of this research is to find out the comparison of monitoring toddler growth and development using the Rajabalita Application and the KIA BookThis research method uses a true-experimental research design, two groups with a pre- and post-test design. The sampling technique is Simple Random Sampling with a sample size of 100 people. Univariate data analysis and bivariate analysis with Dependent T-Test and Independent T-TestThe research results obtained from all respondents, 100 toddlers (100%), were all in normal development status. And it is known that the largest percentage of the quality of the KIA book is the level of relevance of the information, namely 64%, while the largest percentage of the quality of the application is the quality of the timeliness of the information, namely 80%.In conclusion, it can be seen that using the Rajabalita Application is very useful and effective in monitoring the growth and development of toddlers during the pandemicSuggestions: Researchers suggest continuing to carry out activities that involve the community in preventing stunting with methods that continue to innovate, and using a variety of media, so that more people will be interested in getting involved, and in the end it can raise community awareness and independence. Keyword : Toddler; Application; Rajabalita;  KIA; Growth and development