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Analisis komparatif kandungan metabolit pada daun mutan tanaman Torbangun (Plectranthus amboinicus (Lour.) Spreng.): Analisis komparatif kandungan metabolit pada daun mutan tanaman Torbangun (Plectranthus amboinicus (Lour.) Spreng.) Syarifah Iis Aisyah; Henny Rusmiyati; Dewi Sukma; Rizal Damanik; Waras Nurcholis
AGROSAINSTEK: Jurnal Ilmu dan Teknologi Pertanian Vol 4 No 1 (2020): AGROSAINSTEK: Jurnal Ilmu dan Teknologi Pertanian
Publisher : Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/agrosainstek.v4i1.109

Abstract

Torbangun (Plectranthus amboinicus) is a medicinal plant belonging to the Lamiaceae family. In Batak society, the torbangun leaves are consumed to increase breast milk production. The phytochemical variability can be improved by gamma-ray irradiation for plant breeding programs. In this work, a non-targeted metabolomics method was followed to evaluate the compounds profile of irradiated mutant and wild-type on leaves of P. amboinicus. GC-MS analyses evaluated the mutant putative (derived from gamma-ray irradiation) and wild-type plantlets. The resulting of GC-MS data were analyzed with chemometric analysis using hierarchical cluster analysis (HCA). The chemical diversity was showed in mutant and wild-type P. amboinicus. The major metabolite in plantlet wild-type were hydroxymethylfurfural (35.15%), brevifolin (7.69%), 3-Dihydro-3,5-Dihydroxy-6-Methyl-4H-Pyran-4-one (DDMP) (13.13%), stigmasterol (6.51%) and ferruginol (8.63%). However, the compound of DDMP (19.57%), neophytadiene (8.47%), linolenic acid (9.10%), ferruginol (7.61%), stigmasterol (14.14%) and gamma-sitosterol (7.08%) were identified in mutant plantlet. HCA showed diversity between wild-type and mutant plantlets, which highest content of DDMP and stigmasterol and lowest of hydroxymethylfurfural of mutant plantlet.
Transformational Leadership, Training and Their Effects on Employee Engagement of Family Planning Fieldworkers in Indonesia Wahidin Wahidin; Hamidah Hamidah; M. Rizal Martua Damanik; Arum Fitria
Journal of International Conference Proceedings (JICP) Vol 3, No 3 (2020): Proceedings of The 1st Virtual International Conference on Economics, Business &
Publisher : AIBPM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32535/jicp.v2i5.930

Abstract

The issuance of Law of the Republic of Indonesia Number 23 of 2014 concerning Regional Government has an extraordinary impact on the management of Human Resources at The National Population and Family Planning Board (BKKBN), which is The Family Planning Fieldworkers (PKB) that previously had been managed by the regency/city government, after the regulation, the management authority shifted to BKKBN. This study aims to analyze the effect of training variables on transformational leadership, the effect of training variables on employee engagement, and the influence of transformational leadership variables on employee engagement, and to analyze the effect of training variables on employee engagement through mediating the transformational leadership variable. This study used 397 respondents of The Family Planning Fieldworkers who were spread throughout Indonesia. This study used a questionnaire with references to existing theories accompanied by trials to determine the level of validity and reliability. To find out the relationship between variables, Structural Equation Modeling (SEM) analysis techniques are used which are operationalized through the LISREL program. The results showed: (1) The training conducted for Family Planning Fieldworkers had a significant effect on the Transformational Leadership variable, namely t count (7.66) > t table (1.96) with a coefficient value of 0.41; (2) The training given to Family Planning Fieldworkers has a statistically significant effect on employee engagement, namely t count (7.93) > t table (1.96), with a coefficient value of 0.50; (3) Transformational Leadership has a significant effect on employee engagement, namely t arithmetic (2.66) > t table (1.96), while the coefficient value is 0.14; (4) Training of Family Planning Fieldworkers significant effect on Employee Engagement through mediation of Transformational Leadership variables, which is obtained t value (2.72) > t table (1.96), while the coefficient value is 0.06.
The Ethyl Acetate Fraction of Torbangun (Coleus amboinicus L.) Leaves Increasing Milk Production With Up-Regulated Genes Expression of Prolactin Receptor Ade Chandra Iwansyah; Rizal Martua Damanik; Lilik Kustiyah; Muhammad Hanafi
Journal of Tropical Life Science Vol. 9 No. 2 (2019)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aim was to determine lactagogue effect of torbangun leaves to plasma levels of lactogenic hormone and gene expression of their receptors in mammary glands of lactation rats. Lactagogue activity was evaluated by volume of milk was produced by the rats treated with commercial milk booster contained ‘katuk' leaves extract (AF), ethyl acetate fraction of torbangun leaves (EA), water extraction of torbangun leaves (AQ) and kaempferol (KP). Lactating rats (n=5) of Sprague dawley with six pups were fed with AF, EA, AQ, and KP in the amount of 50 mg/kg, 30 mg/kg, 80 mg/kg and 60 mg/kg body weight, respectively. The feed was given orally every two days and starting from day 2 after giving birth until day 28. The volume of milk was estimated by the increment pup weight after breastfed. The levels of serum lactogenic hormones were determined by ELISA methods. Moreover, in order to measure the gene expression of the lactogenic hormone's receptors in the mammary gland a real time - reverse transcription polymerase chain reaction (RT-PCR) method was performed. The results showed that ethyl acetate fraction of torbangun leaves (EA) (a) was not significantly stimulating the synthesis of serum prolactin and estradiol at day 14 and day 28 lactation period, (b) down-regulated the gene expression of estradiol receptor (ERα) at day 28, and (c) up-regulated the gene expression of prolactin receptor (PRLR) in mammary gland at day 14 and day 28. This study indicated that ethyl acetate fraction of torbangun leaves was induced milk production, within up-regulated the gene expression of prolactin receptor (PRLR) in the mammary gland of lactation rats.
RESPONS SEL EPITEL USUS (CMT-93) TERHADAP NUTRASETIKAL GALOHGOR Katrin Roosita; Rimbawan R; Ita Djuwita; M. Rizal Damanik; Clara M. Kusharto
Jurnal Kedokteran Hewan Vol 9, No 2 (2015): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.665 KB) | DOI: 10.21157/j.ked.hewan.v9i2.2825

Abstract

Penelitian ini bertujuan membandingkan pengaruh nutrasetikal galohgor dalam bentuk serbuk (GS) dan ekstrak (GE) terhadap proliferasi, morfologi, dan ekspresi gen Aldh1a2 pada sel epitel usus (CMT-93). Galohgor serbuk (GS) dibuat dengan menghancurkan semua bahan dandikeringkan menggunakan drum-dryer sedangkan GE dibuat dengan mengeringkan semua bahan dengan oven, digiling, dan dimaserasi dengan etanol selama 3x24 jam. Perlakuan didasarkan pada konsentrasi akhir β-karoten yang berasal dari GS dan GE masing-masing sebesar 0,5; 1,5; dan 5,0 µM dalam larutan medium Dulbecco's Modified Eagle's medium (DMEM) yang dilengkapi serum (10%). Analisis proliferasimenggunakan asai 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), dan ekspresi gen dianalisis dengan reverse transcriptasepolymerase chain reaction (RT-PCR). Hasil penelitian meunjukkan bahwa GE pada konsentrasi tinggi (5,0 μM) secara signifikan (P0,05) dapatmenekan proliferasi dan memengaruhi morfologi sel CMT-93. Beta-karoten dalam GE dan GS memengaruhi ekspresi gen Aldh1a2 pada sel epitel usus CMT-93
RESPONS SEL EPITEL USUS (CMT-93) TERHADAP NUTRASETIKAL GALOHGOR Katrin Roosita; Rimbawan R; Ita Djuwita; M. Rizal Damanik; Clara M. Kusharto
Jurnal Kedokteran Hewan Vol 9, No 2 (2015): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v9i2.2825

Abstract

Penelitian ini bertujuan membandingkan pengaruh nutrasetikal galohgor dalam bentuk serbuk (GS) dan ekstrak (GE) terhadap proliferasi, morfologi, dan ekspresi gen Aldh1a2 pada sel epitel usus (CMT-93). Galohgor serbuk (GS) dibuat dengan menghancurkan semua bahan dandikeringkan menggunakan drum-dryer sedangkan GE dibuat dengan mengeringkan semua bahan dengan oven, digiling, dan dimaserasi dengan etanol selama 3x24 jam. Perlakuan didasarkan pada konsentrasi akhir β-karoten yang berasal dari GS dan GE masing-masing sebesar 0,5; 1,5; dan 5,0 µM dalam larutan medium Dulbecco's Modified Eagle's medium (DMEM) yang dilengkapi serum (10%). Analisis proliferasimenggunakan asai 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), dan ekspresi gen dianalisis dengan reverse transcriptasepolymerase chain reaction (RT-PCR). Hasil penelitian meunjukkan bahwa GE pada konsentrasi tinggi (5,0 μM) secara signifikan (P0,05) dapatmenekan proliferasi dan memengaruhi morfologi sel CMT-93. Beta-karoten dalam GE dan GS memengaruhi ekspresi gen Aldh1a2 pada sel epitel usus CMT-93
Factors associated with stunting among children 0-23 months in Aceh: A cross-sectional study using SSGI 2021 Aripin Ahmad; Abidah Nur; Teuku Muliadi; Nelly Marissa; Iflan Naufal; Marisa Marisa; Junaidi Junaidi; Fitrah Reynaldi; Eva Fitriyaningsih; Husnah Husnah; Muhammad Rizal Martua Damanik; Ardi Adji; Syuja' Rafiqi; Devita Annisa
AcTion: Aceh Nutrition Journal Vol 9, No 3 (2024): September
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v9i3.1824

Abstract

Stunting is a chronic health problem that affects children and has long-term implications for their cognitive development. The multifactorial causes of stunting require identification of the most dominant factors to facilitate effective interventions. This study aimed to analyze the factors associated with stunting in children under two years old in Aceh. This was a cross-sectional study involving 2,395 subjects aged 0-23 months. Data were obtained from the 2021 SSGI National Survey, consisting of stunting prevalence, child and family characteristics, household sanitation, universal health insurance ownership, breastfeeding and complementary feeding practices, immunization status, parenting and pregnancy classes, supplementary feeding, and food security. Logistic regression analysis was performed using 95% confidence intervals. The results showed a significant association between stunting and child sex, sanitation conditions, parental education, exclusive breastfeeding, complementary feeding practices, immunization status, micronutrient supplementation, and breastfeeding duration (p<0,05). In conclusion, the factors associated with stunting in children aged 0-23 months in Aceh are sanitation, parental education, exclusive breastfeeding, complementary feeding practices, immunization, micronutrient supplementation, and breastfeeding duration. This study highlights the importance of improved nutrition education, family support, immunization coverage, and environmental sanitation to reduce the prevalence of stunting among young children in Aceh
The Role of Communication Satisfaction in Improving the Effectiveness of Communication and Organizational Performance of Family Planning Extension Centers Adi, Fajar; Muljono, Pudji; Martua Damanik, M. Rizal; M. Anwas, E. Oos
JALOW | Journal of Agribusiness and Local Wisdom Vol. 7 No. 1 (2024): Journal of Agribusiness and Local Wisdom
Publisher : Program Studi Agribisnis bekerja sama dengan PERHEPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jalow.v7i1.41708

Abstract

The Family Planning Program (FP) is one of the Government's efforts to improve community welfare, through child birth regulation. This study aims to analyze the effect of communication satisfaction on communication effectiveness and organizational performance of FP extension centers. This study is descriptive explanatory using statistical analysis and survey design. The Slovin formula is used to determine the number of samples, with a total sample of 430 samples and the sampling technique used is stratified random sampling. There is a positive and significant influence of communication satisfaction on the effectiveness of organizational communication in the FP extension center and the organizational performance of the FP extension center. Central and local governments, as well as other related parties in order to pay attention to the communication satisfaction in improving the effectiveness of communication and organizational performance of FP extension centers