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All Journal Bionatura Dentika Dental Journal MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Journal of Dentomaxillofacial Science B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah Oceana Biomedicina Journal Padjadjaran Journal of Dental Researchers and Students Journal of Case Reports in Dental Medicine Jurnal Material Kedokteran Gigi MDJ (Makassar Dental Journal) Denta: Jurnal Kedokteran Gigi Odonto dental journal Jurnal of Syiah Kuala Dentistry Society
Riani Setiadhi
Departemen Ilmu Penyakit Mulut, Fakultas Kedokteran Gigi, Universitas Padjadjaran, Bandung, Jawa Barat
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Management of chronic traumatic ulcer mimicking oral squamous cell carcinoma on the tongue Revi Nelonda; Riani Setiadhi
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 2 (2018): June 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v51.i2.p76-80

Abstract

Background: Traumatic ulcers represent the most common oral mucosal lesions that can be differentiated from oral squamous cell carcinoma (OSCC) by their clinical appearance. From a clinical perspective, OSCC may resemble a chronic traumatic ulcer (CTU) because the base of the CTU that is healing is filled with reddish-pink granulated tissue, similar to that in OSCC. Purpose: The aim of this case report is to provide information about the oral management of a CTU case that imitates OSCC. Case: A 30-year old female presented with a major, painful, non-healing ulcer located on the right lateral of the tongue for the previous two months. Approximately two years before, she had experienced a similar lesion on the tongue. Intra oral examination showed a 10mm x 5mm yellowish ulcer with a fibrous center, erythematous irregular-induration margin and concave yellow base. The 15th, 44th and 47th teeth were sharp and on occlusion caused trauma to the right lateral border of the tongue. Case management: Based on the clinical features, the lesion was imitating OSCC. After a case history review, clinical examination and appropriate investigation, the patient was diagnosed as suffering from a chronic traumatic ulcer. The primary treatment of traumatic ulcers involves eliminating etiological factors. As pharmacological therapy, a mixture of triamcinolone acetonide and 1mg dexamethasone tablet was administered in addition to folic acid and vitamin B12. Conclusion: Clinical presentation of traumatic lesions varies significantly and may, at times, be ambigous. It is important to immediately establish a correct diagnosis and implement prompt treatment of CTU lesions because they play a role at the oral carcinogenesis promotion stage.
Penatalaksanaan ulserasi oral yang dipicu siklofosfamid pada pasien limfoma sel-B high-grade stadium IV disertai febrile neutropeniaManagement of cyclophosphamide triggered oral ulceration in high-grade B-cell lymphoma stage IV with febrile neutropenic patients Etis Duhita Rahayuningtyas; Riani Setiadhi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 31, No 3 (2019): Desember 2019
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v31i3.23838

Abstract

Pendahuluan: Limfoma sel-B merupakan keganasan sel darah putih tipe non-Hodgkin yang paling sering ditemukan. Gold standard therapy pada kasus ini adalah kemoterapi, akan tetapi obat kemoterapi yang digunakan memberikan efek samping dan mengakibatkan kondisi klinis tertentu setelah beberapa kali pemaparan. Siklofosfamid sebagai salah satu obat kemoterapi, memberikan efek samping berupa penurunan jumlah sel darah putih dan ulserasi pada mukosa mulut. Terputusnya kontinuitas jaringan pada ulser di mukosa mulut mengakibatkan infeksi menjadi lebih patogen dan terjadi nekrosis jaringan. Tujuan laporan kasus ini adalah mengulas ulserasi yang diakibatkan oleh obat kemoterapi seperti siklofosfamid. Laporan kasus: Pasien datang ke Instalasi Gawat Darurat (IGD) Rumah Sakit Hasan Sadikin (RSHS) dengan kondisi lemah dan demam setelah menjalani kemoterapi ke-6 untuk pengobatan limfoma sel-B high grade stadium IV. Obat kemoterapi yang digunakan adalah siklofosfamid, doxorubicin, dan vinkristin. Pasien juga diberi prednison dan rituximab. Pasien tidak dapat mengonsumsi makanan dan minuman dengan optimal karena terdapat sariawan pada mulut. Hasil pemeriksaan laboratorium menunjukkan adanya penurunan nilai hemoglobin, hematokrit, eritrosit, dan leukosit (neutrofil segmen), serta peningkatan nilai ureum dan kreatinin. Ulser nekrotik ditemukan pada jari manis kiri, dan mukosa bukal kiri pasien. Perawatan dilakukan secara komprehensif oleh dokter bagian Ilmu Penyakit Dalam, Ilmu Penyakit Mulut, dan Bedah Plastik. Ulser pada mulut diterapi dengan obat kumur chlorhexidine digluconate 0.12% dan tablet asam folat 400 mcg. Ulser rongga mulut mengalami perbaikan, menyebabkan asupan makanan menjadi lebih baik, sehingga kondisi umum pasien membaik. Simpulan: Penatalaksanaan ulserasi oral yang dipicu siklofosfamid pada pasien limfoma sel-B high-grade stadium IV disertai febrile neutropenia dilakukan dengan terapi farmakologis chlorhexidine digluconate 0.12% dan tablet asam folat 400 mcg, dan terapi non farmakologis berupa instruksi pembersihan gigi dan lidah, memperbanyak minum air putih, menghindari makanan bertekstur keras, dan melakukan kompres ulser mulut yang dimonitor per hari dengan kepatuhan terapi yang dijalani oleh pasien, menghasilkan kondisi umum membaik, dan ulser sembuh pada hari ke-13.Kata kunci: Siklofosfamid, febrile neutropenia, limfoma sel-B. ABSTRACTIntroduction: B-cell lymphoma is the most common type of non-Hodgkin's white blood cell malignancy. Gold standard therapy of this case is chemotherapy, but the chemotherapy medications used have side effects and cause certain clinical conditions after several exposures. Cyclophosphamide as one of the chemotherapy medication, provides side effects in the form of a decreasing number of white blood cells and oral mucosa ulcer. Disconnection of tissue continuity in the oral mucosa ulcers causes infection to become more pathogenic and tissue necrosis will occur. The purpose of this case report was to review the ulcerations caused by chemotherapy medications such as cyclophosphamide. Case report: Patient came to the Hasan Sadikin Hospital Emergency Installation with a weak condition and fever after undergoing the 6th chemotherapy for the treatment of high-grade B-lymphoma stage IV. The chemotherapy medications used were cyclophosphamide, doxorubicin, and vincristine. Patients were also given prednisone and rituximab. Patients also unable to ate and drank optimally because there was an oral ulcer. The laboratory tests results showed a decreasing value of haemoglobin, haematocrit, erythrocytes, and leukocytes (neutrophil segments), as well as an increasing amount of ureum and creatinine. The necrotic ulcer was found on the left ring finger, and the left buccal mucosa. The treatment was performed comprehensively by doctors from the Department of Internal Medicine, Oral Medicine, and Plastic Surgery. The oral ulcer was treated with 0.12% chlorhexidine digluconate mouthwash and 400 mcg of folic acid tablets. The oral ulcer has improved, causing better food intake, thus improving the patient's general condition. Conclusion: The management of cyclophosphamide triggered oral ulceration in high-grade B-cell lymphoma stage IV with febrile neutropenic patients is carried out with pharmacological therapy in the form of 0.12% chlorhexidine digluconate and 400mcg of folic acid tablets, and non-pharmacological therapy in the form of instructions for cleaning teeth and tongue, increase drinking water habit, avoiding hard textured food, and compressing the oral ulcer which must be monitored daily with adherence to the therapy undertaken by the patient, results in improved general conditions, and the ulcer heals on the 13th day.Keywords: Cyclophosphamide, febrile neutropenia, B-cell lymphoma.
Perawatan rekurensi HSV-1 dan eritema multiforme yang dipicu oleh kapsaisin yang terkandung dalam cabai rawit (Capsicum frutescens)Treatment of HSV-1 recurrence and erythema multiforme triggered by capsaicin of tabasco pepper (Capsicum frutescens) Dewi Kania Intan Permatasari; Riani Setiadhi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 31, No 3 (2019): Desember 2019
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v31i3.23843

Abstract

Pendahuluan: Eritema multiforme (EM) adalah suatu kondisi mukokutaneus akut sebagai akibat reaksi hipersensitifitas dengan berbagai etiologi, salah satu pencetusnya disebabkan oleh zat adiktif pada cabai rawit (Capsicum frutescens). Cabai rawit memiliki zat aktif yang dinamakan kapsaisin. Rangsangan kapsaisin pada neuron yang terinfeksi herpes simplex virus-1 laten menyebabkan reaktivasi. Kapsaisin sebagai zat pemberi rasa pada makanan harus menjadi perhatian karena panas yang ditimbulkan dapat menyebabkan terjadinya eritema multiforme. Tujuan dari pembuatan laporan kasus ini adalah melaporkan hasil perawatan rekurensi HSV-1 dan eritema multiforme yang dipicu oleh kapsaisin yang terkandung dalam cabai rawit. Laporan kasus: Seorang wanita berusia 50 tahun, datang ke instalasi Ilmu Penyakit Mulut Rumah Sakit Gigi dan Mulut Universitas Padjadjaran (RSGM Unpad) dengan keluhan terdapat luka di bibir kiri bawah sejak 1 bulan sebelumnya dan belum sembuh. Luka pada bibir ini terjadi untuk yang kedua kalinya. Pasien memiliki kebiasaan mengkonsumsi cabai rawit berlebihan dalam makanannya. Pemeriksaan ekstra oral mendapatkan lesi pada bibir bawah kiri berupa krusta sanguinolenta dengan tendensi perdarahan, bibir atas dan bawah kering serta eksfoliatif. Pemeriksaan intra oral tidak menemukan lesi di rongga mulut. Hasil pemeriksaan laboratorium menunjukkan peningkatan nilai anti HSV-1 IgG dan IgE. Terapi non farmakologis yang diberikan yaitu oral hygiene instructions dan menghindari makanan pedas/cabai rawit; serta terapi farmakologis berupa kompres NaCl 0,9%, asiklovir oral dan krim hidrokortison 1%. Kunjungan ke-3 lesi pada bibir pasien sudah sembuh. Simpulan: Terapi non farmakologis berupa oral hygiene instructions dan menghindari makanan pedas/cabai rawit serta terapi farmakologis berupa kompres NaCl 0,9%, asiklovir  oral dan krim hidrokortison 1% dapat menyembuhkan pasien dengan rekurensi HSV-1 dan eritema multiforme yang dipicu oleh kapsaisin yang terkandung dalam cabai rawit.Kata kunci: Cabai rawit, kapsaisin, HSV-1, eritema multiforme. ABSTRACT            Introduction: Erythema multiforme (EM) is an acute mucocutaneous condition as a result of hypersensitivity reactions with various etiologies, one of which is caused by an addictive substance on tabasco pepper (Capsicum frutescens). Tabasco pepper has an active substance called capsaicin. Stimulation of capsaicin in neurons infected with latent herpes simplex virus-1 causes reactivation. Capsaicin as a food-flavouring agent must be a concern because the heat generated can cause erythema multiforme. The purpose of this case report was to report the results of the treatment of HSV-1 recurrence and erythema multiforme triggered by capsaicin of tabasco pepper. Case report: A 50-year-old woman came to the Oral Medicine Installation of Universitas Padjadjaran Dental Hospital (RSGM Unpad) with a complaining a wound on the lower left lip since the previous month and had not healed since. This lip injury occurred the second time. Patients have a habit of consuming excessive tabasco pepper in every meal. An extraoral examination found lesions on the left lower lip in the form of sanguinolent crust with a tendency to bleed, upper and lower lip dry and exfoliative. An intraoral examination found no lesions in the oral cavity. Laboratory tests showed an increase in anti-HSV-1 IgG and IgE values. Non-pharmacological therapies given were oral hygiene instructions and avoiding spicy foods/tabasco pepper, and pharmacological treatment in the form of 0.9% NaCl compress, oral acyclovir, and 1% hydrocortisone cream. In the 3rd visit, the lesion on the patient's lips has healed. Conclusion: Non-pharmacological therapy in the form of oral hygiene instructions and avoiding spicy foods/tabasco pepper as well as pharmacological treatment in the form of 0.9% NaCl compress, oral acyclovir, and 1% hydrocortisone cream able to cure patients with HSV-1 recurrence and erythema multiforme triggered by capsaicin of tabasco pepper.Keywords: Tabasco pepper, capsaicin, HSV-1, erythema multiforme.
Kandidiasis pada anak dengan lupus eritematosus sistemik disertai ko-infeksi tuberkulosisCandidiasis in children with systemic lupus erythematosus with tuberculosis co-infection Tuty Amalia; Riani Setiadhi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 31, No 3 (2019): Desember 2019
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v31i3.23361

Abstract

Pendahuluan: Kandidiasis oral adalah salah satu infeksi oportunistik yang sering dijumpai pada penderita lupus eritematosus sistemik, yaitu suatu penyakit autoimun yang menyebabkan terjadinya inflamasi kronis multiorgan. Prevalensi tuberkulosis lebih tinggi pada penderita lupus eritematosus sistemik disebabkan adanya kelainan imun yang diderita serta terapi immunosupresif yang diterima. Tujuan penulisan laporan kasus ini adalah menggambarkan lupus eritematosus sistemik disertai ko-infeksi tuberkulosis sebagai faktor predisposisi terjadinya kandidiasis oral. Laporan kasus: Seorang perempuan berusia 16 tahun dikonsultasikan oleh bagian Ilmu Kesehatan Anak dengan keluhan bercak putih di seluruh rongga mulut, terasa perih, dan tidak dapat makan sejak 3 hari sebelumnya, terdiagnosis lupus eritematosus sistemik sejak 1 tahun sebelumnya, dan tuberkulosis sejak 1 bulan sebelum masuk rumah sakit. Pemeriksaan ekstra oral menemukan konjungtiva anemis, sklera non ikterik. Kelenjar getah bening servikal kanan teraba sakit saat palpasi, bibir kering dan deskuamasi, sudut mulut terdapat celah memanjang. Pemeriksaan intra oral mendapatkan plak putih dapat dikerok dan meninggalkan daerah eritema pada mukosa labial atas dan bawah, mukosa bukal kiri dan kanan, dorsum lidah, lateral lidah kiri dan kanan. Terdapat lesi erosif yang terasa sakit, ukuran 20 x 2 mm pada ventral lidah. Eritema multipel di palatum tidak terasa sakit saat palpasi. Diagnosis kondisi oral adalah kandidiasis pseudomembran akut. Terapi yang diberikan ialah chlorhexidine digluconate 0,12% dan nistatin suspensi oral, pasien mengalami perbaikan pada hari ketiga terapi. Simpulan: Terapi lupus eritematosus sistemik disertai ko-infeksi tuberkulosis dengan faktor predisposisi terjadinya kandidiasis oral.adalah chlorhexidine digluconate 0,12% dan nistatin suspensi oral, pasien mengalami perbaikan pada hari ketiga terapi.Kata kunci: Kandidiasis pseudomembran akut, lupus eritematosus sistemik, tuberkulosis. ABSTRACTIntroduction: Oral candidiasis is an opportunistic infection often found in patients with systemic lupus erythematosus, an autoimmune disease that causes chronic multiorgan inflammation. The prevalence of tuberculosis is higher in patients with systemic lupus erythematosus due to the presence of immune disorders as well as the side effect of immunosuppressive therapy. This case report was aimed to describe systemic lupus erythematosus with tuberculosis co-infection as a predisposing factor for oral candidiasis. Case report: A 16-year-old woman was consulted from the Paediatrics Department with white spots all over the oral cavity with sore feeling and could not eat since 3 days before, was diagnosed with systemic lupus erythematosus since 1 year back, and tuberculosis since 1 month before hospitalised. An extraoral examination found anaemic conjunctiva and non-jaundice sclera. The right cervical lymph node feels pain when palpation, dry lips and desquamation, the corners of the mouth were found elongated fissures. Intraoral examination to get white plaque can be scraped off and leave erythema areas on the upper and lower labial mucosa, left and right buccal mucosa, dorsum of the tongue, lateral left and right tongue. There was a painful erosive lesion with a size of 20 x 2 mm on the ventral tongue. Multiple erythemas in the palate did not hurt when palpation. The diagnosis of an oral condition is acute pseudomembranous candidiasis. Therapy given was 0.12% chlorhexidine digluconate and nystatin oral suspension; the patient experienced improvement on the third day of treatment. Conclusion: Systemic lupus erythematosus with tuberculosis co-infection therapy with predisposing factors of oral candidiasis are 0.12% chlorhexidine digluconate and nystatin oral suspension; the patient experienced improvement on the third day of the treatment.Keywords: Acute pseudomembranous candidiasis, systemic lupus erythematosus, tuberculosis.
Kondisi kesehatan gigi dan mulut siswa SDK YahyaOral health conditions of the Yahya Christian Elementary School students Rosiliwati Wihardja; Riani Setiadhi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 1 (2018): April
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.335 KB) | DOI: 10.24198/jkg.v30i1.16247

Abstract

Pendahuluan: Rongga mulut terdiri dari jaringan lunak maupun jaringan keras, serta merupakan anggota tubuh yang penting untuk dijaga seperti anggota tubuh lainnya. Tujuan penelitian ini adalah untuk mengetahui kondisi kesehatan gigi dan mulut siswa SDK Yahya. Metode: Jenis penelitian deskriptif. Data penelitian diambil dari formulir kesehatan gigi dan mulut siswa SDK Yahya dan disajikan dalam bentuk tabel distribusi frekuensi. Hasil: Sebagian besar siswa mempunyai gingiva, mukosa bukal, mukosa labial, frenulum, lidah, dan saliva yang normal serta seluruh siswa mempunyai palatum keras dan lunak yang normal. Persentase karies, tambalan dan  gigi yang hilang pada siswa tergolong kecil dan nilai oral higyenenya nilai yang kecil. Keadaan ini menunjukkan bahwa umumnya siswa mempunyai kesehatan jaringan lunak dan keras yang baik serta keadaan oral hygiene yang baik. Simpulan: Kondisi kesehatan gigi dan mulut siswa SDK Yahya mayoritas tergolong dalam kondisi normal dengan oral hygiene dalam kondisi baik.Kata kunci: Kesehatan gigi dan mulut, siswa SD. ABSTRACTIntroduction: The oral cavity consists of both hard and soft tissues that are vital to be maintain like the other part of the body. Improving knowledge and behavior which was given since school age could overcome the incidence of oral health problems. Tujuan penelitian ini adalah untuk mengetahui kondisi kesehatan gigi dan mulut siswa SDK Yahya. Methods: This was a descriptive study using oral health form of both hard and soft tissues of students from Yahya Christian Elementary School. Results: This study revealed that most students had normal gingiva, buccal mucosa, labial mucosa, frenulum, tongue and saliva, and also normal palatum durum and molle. The percentage of cavities, fillings and tooth-loss on the students was considered as small. Such findings demonstrated that in general, the students had decent integrity of both soft and hard oral tissues. Conclusion: Oral health conditions of the Yahya Christian Elementary School students were generally observed in the normal state.Keywords: Oral health condition, elementary school students.
Pengaruh umur terhadap jaringan lunak mulut siswa usia sekolah dasarEffect of age on the oral soft tissue of elementary school-age students Riani Setiadhi; Rosiliwati Wihardja
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 31, No 2 (2019): Agustus 2019
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.33 KB) | DOI: 10.24198/jkg.v31i2.19368

Abstract

Pendahuluan: Umur merupakan salah satu faktor yang mempengaruhi perilaku kesehatan seseorang.  Semakin bertambahnya umur dan semakin tingginya pendidikan maka semakin tinggipengetahuan mengenai kebersihan mulut sehingga diharapkan kebersihan mulut akan lebih baik sejalan dengan pertambahan umur. Rongga mulut terdiri dari jaringan keras dan jaringan lunak. Jaringan lunak rongga mulut terdiri dari mukosa labial, mukosa bukal, palatum, gingiva, frenulum dan lidah. Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh umur terhadap jaringan lunak mulut siswa. Metode: Penelitian ini merupakan analitik crossectional terhadap  data /catatan kesehatan gigi siswa SDK Yahya meliputi umur dan keadaan jaringan lunak mulut. Populasi dalam penelitian ini adalah seluruh data /catatan kesehatan jaringan lunak siswa SDK Yahya tahun ajaran 2012–2013. Jumlah sampel dihitung dengan rumus besaran sampel minimal : n = N/N(d)2 + 1 dan didapatkan jumlah sampel adalah 180.12 Setelah mendapatkan jumlah sampel minimal, metode pengambilan sampel yang digunakan adalah sampling sistematis. Hasil: Secara umum kondisi jaringan lunak mulut siswa-siswa yang diperiksa adalah baik. Uji t menunjukkan pengaruh parsial signifikan pada 3 kondisi jaringan mulut yaitu bibir normal, bibir kering dan lidah normal. Uji hipotesis  (Uji F) menunjukkan pengaruh umur terhadap kondisi jaringan lunak mulut menunjukkan nilai F hitung (4,224) > F tabel (1,686), sehingga Ho ditolak artinya secara simultan terdapat pengaruh yang signifikan dari umur terhadap kondisi jaringan lunak mulut. Simpulan: Terdapat pengaruh umur terhadap kesehatan jaringan lunak mulut siswa usia sekolah dasar.Kata kunci: Umur, jaringan lunak mulut, siswa sekolah dasar ABSTRACTIntroduction: Age is one of the factors that influence an individual’s health behaviour. The more you get older and the higher the education, the higher your knowledge about oral hygiene thus expected that oral hygiene would be better in line with aging. The oral cavity consists of hard and soft tissue. Oral soft tissue consists of labial mucosa, buccal mucosa, palate, gingiva, frenulum and tongue. This study was aimed to determine the influence of age on the oral soft tissues of elementary students. Methods: This study was a cross-sectional analytic of dental records of Yahya students, including the students’ age and oral soft tissue condition. The population in this study were all dental records of Yahya Christian Elementary School students’ regarding the health of soft tissue, from 2012 to 2013 school year. The number of samples was calculated with a minimum sample size formula: n = N/N(d) 2 + 1 and the number of samples obtained is 180. After getting the minimum number of samples, the sampling method used was systematic sampling. Results: In general, the oral soft tissue condition of the students examined was good. The t-test showed a significant partial effect on 3 conditions of oral tissue, namely normal lips, dry lips, and normal tongue. Hypothesis test (F-test) on the effect of age on the condition of oral soft tissue showed the calculated F-value (4.224) > F table (1.686) so that Ho was rejected, meaning that simultaneously, there was a significant effect of age on the condition of oral soft tissue. Conclusion: Students of Yahya Christian Elementary School of the 2012-2013 school year have good oral soft tissue condition, and there was an influence of age on the health of elementary school-age students’ oral soft tissue.Keywords: Age, oral soft tissue, elementary school students
Infeksi herpes simpleks virus 1 rekuren dengan faktor predisposisi stres emosionalRecurrent herpes simplex virus 1 infection with predisposing factors of emotional stress Suniti Suniti; Riani Setiadhi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 3 (2018): Desember
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (504.446 KB) | DOI: 10.24198/jkg.v30i3.17964

Abstract

Pendahuluan: Infeksi Herpes Simpleks Virus 1  (HSV 1) pada rongga mulut merupakan suatu penyakit yang diawali gejala prodromal yaitu demam diikuti munculnya vesikel pada wajah, mukosa mulut, dan bibir. HSV 1 bersifat laten di dalam tubuh  dan dapat rekuren yang dipicu oleh paparan sinar matahari, stres emosional, kondisi imunosupresi, kelainan hormonal dan trauma saraf. Laporan kasus ini bertujuan untuk membahas infeksi HSV 1 rekuren intraoral  (RIH) dengan faktor predisposisi stres emosional. Laporan kasus: Seorang perempuan 35  tahun datang   ke poli Ilmu Penyakit Mulut didiagnosis RIH sejak 3 bulan sebelumnya  dengan keluhan sariawan di lidah dan tenggorokan yang didahului  demam. Ekstra oral tidak ditemukan kelainan sedangkan  intra oral terdapat ulser, dasar kekuningan, tepi ireguler, dikelilingi eritem di lateral lidah kiri, palatum posterior, orofaring  dan gingiva disertai rasa sakit. Hasil pemeriksaan darah anti HSV 1 Ig G reaktif dengan nilai 21,3 pada kunjungan dan 31,4 setelah terjadi kekambuhan. Setelah dilakukan anamnesis yang mendalam,stres emosional diduga sebagai pemicu RIH, dimana musibah yang dialami pasien mengakibatkan stres emosional yang memicu berulangnya RIH. Terapi farmakologis berupa asiklovir sistemik, obat kumur khlorheksidine glukonat, vitamin B12 serta asam folat, sedangkan pengelolaan  stres  diberikan sebagai  terapi non farmakologi. Infeksi  sembuh setelah 3 minggu. Selain terapi farmakologi, pasien ini diberikan motivasi untuk  mengelola stres, terbukti pengelolaan stress dapat mempercepat penyembuhan RIH. Simpulan: Infeksi HSV 1 rekuren intraoral  (RIH) dengan faktor predisposisi stres emosional dapat sembuh dengan terapi farmakologi berupa pemberian antivirus, obat kumur dan vitamin dan terapi non farmakologi pengelolaan stres dalam bentuk self suggestion menunjukkan perbaikan lesi pada minggu kedua dan sembuh pada minggu ketiga.Kata kunci: Infeksi herpes simpleks virus 1 rekuren, stres emosional, tata laksana kasus. ABSTRACT            Introduction: Herpes simplex virus 1 (HSV 1) infection in the oral cavity is a disease that begins with a prodromal symptom which was a fever followed by the appearance of vesicles on the face, oral mucosa, and lips. HSV 1 is latent in the human body and can be recurrently triggered by sun exposure, emotional stress, immunosuppression conditions, hormonal abnormalities, and nerve trauma. This case report was aimed to discuss the recurrent intraoral HSV 1 (RIH) infection with predisposing factors of emotional stress. Case report: A 35-years-old woman who came to the Oral Medicine Clinic was diagnosed with RIH for 3 months before with the chief complaint of oral thrush on the tongue and the throat preceded by a fever. No extraoral abnormalities were found, while intraoral examination results found an ulcer, with the yellowish base, irregular edge, surrounded by erythema lateral to the left tongue, posterior palate, oropharynx, and gingiva, and accompanied with the soreness. The result of anti-HSV 1 Ig G reactive blood tests was 21.3 at the visit and 31.4 after the recurrence. After a thorough anamnesis, emotional stress was considered as the RIH trigger, where a disaster experienced by the patient resulted in emotional stress that triggered the RIH recurrence. Pharmacological therapy was performed in the form of administration of the systemic acyclovir, chlorhexidine gluconate mouthwash, vitamin B12, and folic acid; while stress management was also given as a non-pharmacological therapy. The infection was resolved after 3 weeks. In addition to pharmacological therapy, the patient was given the motivation to manage her stress, and the stress management was proven to accelerate the RIH healing. Conclusion: Recurrent intraoral HSV 1 (RIH) infection with emotional stress as a predisposing factor can be cured with pharmacological therapy in the form of administration of antiviral, mouthwash, and vitamins, with addition of self-suggestion stress management as the non-pharmacological therapy, which were proven to improve the lesions in the 2nd week and recover in the 3rd week.Keywords: Herpes simplex virus 1 infection, emotional stress, case management.
Necrotizing ulcerative stomatitis mimicking erythema multiforme pada pasien dengan HIV seronegatifNecrotizing ulcerative stomatitis mimicking erythema multiforme in HIV seronegative patients Eliza Kristina Munthe; Riani Setiadhi
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 32, No 2 (2020): November 2020 (Suplemen 1)
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v32i2.23868

Abstract

ABSTRAKPendahuluan: Necrotizing ulcerative stomatitis (NUS) merupakan inflamasi akut yang ditandai destruksi, ulserasi serta nekrosis epitel, jaringan ikat dan papila. Umumnya terjadi pada pasien malnutrisi dan Human Immunodeficiency Virus (HIV) seropositif. Lesi awal berupa necrotizing gingivitis kemudian berkembang menjadi necrotizing periodontitis, selanjutnya menjadi NUS. Gambaran klinis kasus NUS kadang serupa dengan Erythema multiforme (EM), sehingga perlu dilakukan pemeriksaan penunjang yang dapat menegakkan diagnosa dengan tepat. Tujuan laporan kasus ini melaporkan cara menegakkan diagnosis NUS yang menyerupai EM secara tepat pada pasien dengan suspek infeksi HIV. Laporan kasus: Pasien laki-laki berusia 49 tahun dirujuk ke departemen Ilmu Penyakit Mulut dengan diagnosis EM disertai suspek terinfeksi HIV. Keluhan utama berupa rasa nyeri disertai sariawan pada lidah dan bibir bagian dalam. Pemeriksaan ekstraoral tidak ada kelainan, pada intraoral ditemukan ulser multipel dilapisi sloughing kekuningan pada mukosa labial, mukosa bukal, dorsal lidah, lateral lidah dan ventral lidah. Gingiva anterior rahang bawah terdapat lesi ulseratif disertai jaringan nekrosis. Pemeriksaan darah menunjukkan penurunan hematokrit, peningkatan leukosit, serta negatif pada pemeriksaan tes HIV. Actinomyces naeslundii ditemukan pada pemeriksaan mikrobiologi. Ditegakkan diagnosis NUS dan terapi yang diberikan amoxicillin 500mg, metronidazol 500mg, chlorhexidine gluconate 0,2% dan asam folat. Lesi oral mengalami perbaikan dalam 2 minggu. Simpulan: Lesi oral mengalami perbaikan secara signifikan setelah kontrol ketiga atau seminggu dari kunjungan pertama, pasien sudah dapat makan tanpa rasa nyeri. Gambaran klinis lesi mukosa oral yang khas, serta pemeriksaan penunjang mikrobiologi berperan dalam menunjang diagnosis NUS. Tes HIV perlu dilakukan untuk mengkonfirmasi status infeksi HIV pada pasien. Dokter gigi sebaiknya mengenali tanda dan gejala NUS, sehingga dapat menegakkan diagnosis dan memberikan terapi adekuat serta mencegah meluasnya kerusakan jaringan.Kata kunci: Human immunodeficiency virus, lesi oral, necrotizing ulcerative stomatitis, erythema multiforme. ABSTRACTIntroduction: Necrotizing ulcerative stomatitis (NUS) is an acute inflammation characterised by destruction, ulceration, and necrosis of the epithelium, connective tissue, and papillae. Generally occurs in malnourished and Human Immunodeficiency Virus (HIV) seropositive patients. The initial lesion is found in the form of necrotizing gingivitis then developed into necrotizing periodontitis, which later became NUS. The clinical feature of NUS sometimes similar to the erythema multiforme (EM); thus, it is necessary to conduct investigations to make the diagnosis correctly. This case report was aimed to report on how to properly diagnose an EM-like NUS in a patient with suspected HIV infection. Case report: A 49-years-old male patient referred to the Oral Medicine department with an EM diagnosis with suspected HIV infection. The main complaint is pain accompanied by mouth sores on the tongue and inner lips part. Extraoral examination showed no abnormality, multiple ulcers coated with yellowish sloughing on the labial mucosa, buccal mucosa, dorsal tongue, lateral tongue, and ventral tongue. The anterior mandibular gingiva had ulcerative lesions with tissue necrosis. Blood tests showed a decrease in hematocrit, an increase in leukocytes, and a negative result of the HIV test. Actinomyces naeslundii was found on microbiological examination. Diagnosis of NUS was confirmed, and therapy given were amoxicillin 500 mg, metronidazole 500 mg, chlorhexidine gluconate 0.2%, and folic acid. The oral lesions improved within two weeks. Conclusion: Oral lesions improved significantly after the third control in a week from the first visit, the patient was able to eat without pain. The clinical feature of typical oral mucosal lesions, as well as microbiological examinations, play a role in supporting the diagnosis of NUS. An HIV test needs to be carried out to confirm the HIV infection status of the patient. Dentists should recognise the signs and symptoms of NUS to determine a diagnosis, provide adequate therapy, and prevent the spread of tissue damage.Keywords: Human immunodeficiency virus, oral lesions, necrotizing ulcerative stomatitis, erythema multiforme.
Gambaran klinis smoker’s melanosis pada perokok kretek ditinjau dari lama merokokThe clinical features of smoker's melanosis in kretek smokers by the smoking period Cynthia Vieta; Riani Setiadhi; Cucu Zubaedah
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 29, No 1 (2017): April
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.938 KB) | DOI: 10.24198/jkg.v30i3.18532

Abstract

Pendahuluan: Kebiasaan merokok sudah melekat di masyarakat Indonesia dan tidak lagi dianggap sebagai suatu kebiasaan buruk. Terdapat beberapa jenis rokok, diantaranya adalah rokok kretek. Rokok mengandung berbagai zat yang berbahaya bagi tubuh. Salah satu efek buruk rokok adalah smoker’s melanosis yang merupakan kelainan pigmentasi di rongga mulut. Tujuan penelitian adalah untuk mengetahui gambaran klinis smoker’s melanosis pada perokok kretek ditinjau dari lama merokok. Metode: Penelitian ini dilakukan secara deskriptif dengan metode survei. Sampel yang diambil sebanyak 80 orang dengan menggunakan teknik stratified sampling. Hasil: Sebanyak 46,3% responden yang mengalami pigmentasi meluas ternyata memiliki kebiasaan merokok kretek lebih dari 20 tahun. Simpulan: Frekuensi pigmentasi meluas paling banyak terdapat pada kelompok perokok yang sudah merokok selama lebih dari 20 tahun.Kata kunci: Rokok kretek, smoker’s-melanosis, lama merokok ABSTRACTIntroduction: Smoking habit has been inherent among Indonesian people and no longer considered as a bad habit. There are several types of cigarettes such as kretek cigarettes. Cigarettes contain many substances that harmful to the body. One of the negative effect from cigarettes is smoker’s melanosis which is known as pigmentation disorder in the oral cavity. The aim of this research was to know the clinical feature of smoker’s melanosis in kretek cigarettes smokers from smoking’s duration. Method: This research was done in a descriptive survey method. Samples taken as many as 80 people using stratified sampling. Result: 46,3% of respondents who experienced widespread pigmentation turned out to have a habit of kretek cigarettes smoking for more than 20 years. Conclusion: the frequency of the most widespread pigmentation found in the group of smokers who have been smoking for over 20 years.Keywords: Kretek cigarettes, smoker’s melanosis, smoking’s duration
Inhibition growth of pomegranate seeds extract against streptococcus sanguis: the cause of recurrent aphthous stomatitis Riani Setiadhi; Irna Sufiawati; Dewi Zakiawati; Nanan Nur’aeny; Wahyu Hidayat; Dani R. Firman
Journal of Dentomaxillofacial Science Vol. 2 No. 1 (2017): (Available online: 1 April 2017)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v2i1.452

Abstract

Objective : Pomegranate (Punica granatum L.) seeds contain high of phytonutrients and phytochemicals, rich in polyphenol antioxidants namely tannins and flavonoids which also have antibacterial activity. Streptococcus sanguis is a bacterium known as one of the factors causing Recurrent Aphthous Stomatitis (RAS). To examine the potential antibacterial of Pomegranate seeds against Streptococcus sanguis.Material anda Methods : In vitro study of Pomegranate seed were extracted with maceration method using 70% ethanol as the solvent to obtain stable extract, continued with phytochemical screening against phenolic, flavonoids, alkaloids, steroids, triterpenoid, saponins and tannins.  The extract was evaluated for Minimum Inhibitory Concentration and Minimum Bactericide Concentration against Streptococcus sanguis ATCC 10556, using microdiluted method through 96 wells microplate. Results : Chlorhexidine was used as positive control while 70% ethanol was used as solvent as well as negative control. Phytochemical screening gave positive results for phenolics, flavonoids, steroids, saponins and tannins. Microdilution test showed the concentration of 500 ppm as MIC and MBC value at 2,000 ppm.Conclusion : Pomegranate seeds extract have a growth inhibitory against Streptococcus sanguis with MIC value of 500 ppm and 2,000 ppm as MBC.
Co-Authors Adi Ahmad Yusuf Agustin Ninintowe T. Santo Amira Shafuria Ani Megawati Bakti, Fitrah Utari Cucu Zubaedah Cucu Zubaedah, Cucu Cynthia Vieta Dani R. Firman Dani R. Firman Desi Elvhira Rosa Devi Nasution Dewi Kania Intan Permatasari Dewi Zakiawati Dewi Zakiawati Dewi Zakiawati, Dewi Djou, Rahmatia Eddea Marselyna A.D. Eliza Kristina Munthe Embun Manja Sari Etis Duhita Rahayuningtyas Fika Faradilla Drakel Fika Faradillah Drakel fika faradillah drakel Fitria Mailiza Hamdatun Rakhmania Han, Foo You Heldayani, Iin Her Basuki Margono Hilda Hindasah I Nyoman Gede Juwita Putra I Nyoman Gede Juwita Putra Indah Suasani Wahyuni Indra Gunawan Irna Sufiawati Kartika Indah Sari Kosterman Usri Maghfira Indriawati Iswiningtyas Muhammad A. Farisyi Nanan Nur’aeny Nanan Nur’aeny Nanan Nur’aeny Novia Tri Hasanah Nur'aeny, Nanan Nuri Fitriasari Rahmi Harmiyati Revi Nelonda Revi Nelonda Rosiliwati Wihardja Rosiliwati Wihardja, Rosiliwati Santoso, Astrid Widhowaty Siregar, Fitri Dona Sudjarwo, Indrati Suniti Suniti T. Santo, Agustin Ninintowe Tuty Amalia Vieta, Cynthia Vinna Kurniawati Sugiaman Wahyu Hidayat Wahyu Hidayat Wahyu Hidayat Willyanti Soewondo - Wilma ADIWIJAYA Yanie Febby Martina Lefaan Yannie Febby Martina Lefaan Yongky Tamigoes Yuti Malinda