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Analysis of Flavonids and Terpenoids in Ethanol Extract of Colocasia esculenta L. (Schoot) Stalk and Leaves Erni Rustiani; Aulia Fitriani; Sri Wardatun
Journal of Tropical Pharmacy and Chemistry Vol. 5 No. 4 (2021): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v5i4.349

Colocasia esculenta L. (Schoot) is a widely used plant in developing countries in Asia, Africa, and Central America. The parts of the Colocasia plant that can be used are the tubers, stalks, and leaves. There has not been much research on the content of this plant. The study aims to determine the flavonoids and terpenoids in the ethanol extract of Colocasia stalk and leaves. The maceration method with 70% ethanol solvent and drying with vacuum evaporator. Determination of flavonoid levels based on quercetin marker compounds using AlCl3 reagent by UV-Vis spectrophotometry. The terpenoid levels were carried out gravimetrically with petroleum ether as a solvent. The results showed that the ethanol extract of Colocasia stalk and leaf contained flavonoids, respectively 3.18 +0.0581% and 4.33 +0.0285%, while the results of the terpenoid levels for stalks were 7.10 +0.0676% and leaves were 8.39 +0.0023%.

The Sunscreen activities of ethanol, ethyl acetate, n-hexane, and water fractions from papaya (Carica papaya l.) leaf extract Wardatun, Sri; Mahyuni, Siti; Setiawan, Putra
Indonesian Journal of Pharmaceutics Vol 5, Issue 2, May - August 2023
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v5i2.46557

The application of sunscreen products containing natural compounds is one ofalternative popular ways to protect the skin from the harmful effects of sunexposure. The aim of this study was to evaluate the sunscreen activity of papayaleaf extract. The ethanol extract of papaya leaf was fractionated to obtain ethanol,n-hexane, ethyl acetate, and water extracts. The value of SPF 15, percenttransmission of erythema (1% Te ), and the percent transmission of pigmentation40 (% Tp) of each extract were calculated in vitro by using spectrophotometricmethod. among the extract examined, the ethyl acetate extract was found to be themost effective to reach Sun Protection Factor (SPF) 15 (ultra-protection category)and 1% Te (sunblock category) at a minimum concentration of 90.08 ppm and63.49 ppm. Meanwhile n-hexane extract was the most effective to reach 40% tp(sunblock category) at a minimum concentration of 30.68 ppm. The minimumconcentration of papaya leaf extracts required to reach SPF 15, 1% Te and 40% Tpwere far below the concentration of sunscreen compounds allowed in commercialcosmetic products. It can be concluded that papaya leaf extract have significantsunscreen property for use as cosmetic ingredient.Keywords: Carica papaya, SPF, Transmission of erythema, Transmission ofpigmentation

POTENSI ANTIOKSIDAN BERBAGAI SEDIAAN BUAH SIRSAK [ANONNA MURICATA LINN Prasetyorini Prasetyorini; Moerfiah Moerfiah; Sri Wardatun; Zaldy Rusli
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 37 No. 2 (2014)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v37i2.4017.137-144

ABSTRACTSoursop is a potential source of antioxidant due to high vitamin C and poliphenol content. Antioxidant activity of three different preparations i.e. fruit juice, 96% ethanol extract, and ethyl acetate extract. The antiocdidant were measured by using 1.1-diphenyl-2 pycrihidrazyl (DPPH) radical solution. In addition, vitamin C and polyphenol content of each preparation were also measured. Polyphenol content as measured in gram Gallic Acid Equivalent (GAE)/100 g). Showed the fruit juice, 96% ethanol extract and ethyl acetate extract were 0,473, 0,324, and 0,194, respectively. Vitamin C content (mg/100 g) of these three preparations were 36.24, 30.56, and 35.66, respectively. The antioxidant activities (ppm) determined by IC50 showed fruit juice, 96% ethanol extract and ethyl acetate extract were 282.61 ppm, 660.08 and 480.26, respectively. There was strong correlation between vitamin C content and antioxidant activity, and between polyphenol content and antioxidant activities. In conclusion, the use of fruit juice as antioxidant source was better than ethyl acetate and ethanol 96% extract.Keywords: antioxidant activity, soursop (Annona muricata Linn), poliphenol, vitamin CABSTRAKSirsak memiliki potensi sebagai sumber antioksidan karena kandungan vitamin C dan polifenol yang cukup tinggi. Aktivitas antioksidan dari tiga sediaan sirsak yaitu sari buah, ekstrak etanol 96% dan ekstrak etil asetat. Pengujian antioksidan dilakukan dengan senyawa radikal 1,1-diphenyl-2-pycrilhidrazyl (DPPH). Selain diuji potensi antioksidannya, masing-masing bentuk sediaan juga diukur kadar vitamin C dan kadar polifenolnya. Hasil penelitian menunjukkan kandungan polifenol yang dihitung dalam gram Setara Asam Galat (SAG)/100 g) sari buah, ekstrak etanol 96% dan ekstrak etil asetat berturut-turut adalah 0,473; 0,324 dan 0,194 dan kandungan vitamin C (mg/100 g) berturut-turut adalah 36,24; 30,56, dan 35,66. Aktivitas antioksidan (ppm) yang ditunjukkan oleh nilai IC50, untuk sari buah, ekstrak etanol 96% dan ekstrak etil asetat berturut-turut adalah sebesar 282,61; 660,08 dan 480,26. Hasil uji korelasi menunjukkan bahwa terdapat korelasi yang kuat antara kandungan vitamin C dengan aktivitas antioksidan, dan kadar polifenol dengan aktivitas antioksidan. Pemanfaatan buah sirsak sebagai antioksidan lebih baik menggunakan sediaan sari buah daripada ekstrak etil asetat dan ekstrak etanol 96%. [Penel Gizi Makan 2014, 37(2): 137-144]Kata kunci: aktivitas antioksidan, buah sirsak (Annona muricata Linn), polifenol, vitamin C

Etika Komunikasi Islam dalam Dakwah Media Sosial Tantangan dan Solusi di Tengah Arus Modernitas Lakum, Lakum; Wardatun, Sri; Mardiamah, Suci; Randiansyah, Randiansyah; Marpaung, Juwita Rosvenia
Jurnal Pusat Studi Pendidikan Rakyat Volume 5 Nomor 2 Mei 2025
Publisher : CV. PUSDIKRA MITRA JAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51178/jpspr.v5i2.2470

Perkembangan media sosial saat ini sangat meluas hingga membuka ruang baru bagi aktivitas dakwah islam, yang mana bisa menyampaikan pesan – pesan dakwah secara cepat, luas, dan interaktif. Namun, Media Sosial tidak selalu sejalan dengan nilai nilai etika komunikasi di dalam nya yang meliputi kejujuran, kesantunan, kelembutan dalam menyampaikan dakwah islam. Jurnal ini bertujuan untuk mengkaji bagaimana tantangan dan solusi dalam berdakwah ditengah arus modernitas. Ruang lingkup jurnal ini mencakup platform media sosial yang sedang marak di era saat ini, yaitu tiktok, facebook, instagram, dan Youtube. Metode yang digunakan adalah pendekatan kualitatif dengan teknik studi pustaka. Penelitian berfokus dalam analisis praktik dakwah di media sosial serta gagasan modernitas dengan etika komunikasi islam.

Komunikasi Tentang Pembinaan Remaja, Analisis Tentang Geng Motor yang Ada di Kab. Asahan Nasution, Ismail; Wardatun, Sri; Mardiamah, Suci; Randiansyah, Randiansyah; Almunawaroh, Zahra
Jurnal Pusat Studi Pendidikan Rakyat Volume 5 Nomor 2 Mei 2025
Publisher : CV. PUSDIKRA MITRA JAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51178/jpspr.v5i2.2672

Masalah geng motor di Kabupaten Asahan semakin meningkat, dengan banyak remaja terlibat sebagai pelaku. Penelitian ini mengkaji bagaimana komunikasi berperan dalam proses pembinaan remaja untuk menghindari partisipasi mereka dalam kegiatan geng motor. Penelitian ini menerapkan pendekatan kualitatif melalui wawancara dengan berbagai pihak, termasuk pihak kepolisian, tokoh masyarakat, guru, serta remaja yang pernah menjadi anggota geng motor. Temuan menunjukkan bahwa minimnya komunikasi yang baik di dalam keluarga, sekolah, dan masyarakat adalah salah satu penyebab utama remaja mudah terpengaruh oleh lingkungan yang negatif. Selain itu, remaja yang kurang mendapatkan perhatian serta bimbingan cenderung berusaha menemukan identitas diri di tempat yang tidak tepat, seperti dalam geng motor. Maka dari itu, diperlukan komunikasi yang lebih terbuka, intens, dan mendidik antara orang dewasa dan remaja. Kesimpulan dari penelitian ini adalah bahwa komunikasi yang efektif dapat menjadi kunci penting dalam pembinaan remaja agar tidak terpengaruh oleh geng motor. Peran semua pihak, terutama dari keluarga dan sekolah, sangat dibutuhkan dalam upaya pembinaan tersebut.

Pelatihan Pembuatan Minuman Herbal Sari Buah Pandan Laut (Pandanus tectorius Park.) di Desa Hegarmanah, Kabupaten Lebak, Banten: indonesia Wulandari, Asri; Setiani, Lusi Agus; Wardatun, Sri; Padhilah, Prasti Restu; Sunarya, M. Rustan; Malatabu, Shapira Mera
Jurnal Abdimas Madani dan Lestari (JAMALI) Volume 07, Issue 02, September 2025
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jamali.vol7.iss2.art19

Hegarmanah Village is one of the villages located in Lebak Regency, Banten with the area closest to the Warunghuni coast where sea pandan plants grow (Pandanus tectorius Park.). The sea pandan plant is a wild plant that grows a lot on the coast which is useful for withstanding the impact of the waves and has the effect of minimizing damage to the area behind the pandan vegetation. The community uses sea pandan fruit only for the leaves as raw material for making mats, but the fruit is often thrown away due to lack of knowledge. Sea pandan fruit contains secondary metabolite compounds that are beneficial for health. This community service activity (PKM) aims to increase the community's knowledge and skills in processing sea pandan fruit into herbal drinks to improve the community's health and economy. This PKM activity is carried out in the form of direct training with PKK women at Hegarmanah Village, housewife communities, Karang Taruna youth and village officials with the hope that the community can produce sea pandan juice herbal drinks sustainably and commercialize them as a typical Hegarmanah Village drink. Efforts to increase the selling value of abundant sea pandan fruit into various products with high competitiveness can be realized through continuous coaching and assistance by the community in collaboration with the team from the Pharmacy Study Program, Pakuan University.

Stunting Prevention Education for Adolescents at Al Falak High School, Bogor City Sofihidayati, Trirakhma; Rustiani, Erni; Wardatun, Sri
Jurnal Pengabdian Masyarakat Inovatif Vol. 1 No. 2 (2023): JPMI (Jurnal Pengabdian Masyarakat Inovatif)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jpmi.v1i2.94

Stunting is a condition where growth disorders occur in children which is characterized by a child's lack of height compared to children his age. Several factors cause stunting, especially in the city of Bogor, including lack of nutritional intake in the first 1000 days of life (HPK), early marriage (39 percent), teenagers suffering from anemia (3.52 percent), pregnant women with anemia (11.8 percent ), and the Covid-19 pandemic factor that occurred during the last two years. Anemia in adolescent girls (rheumatism) has an impact on health and performance at school and can be at risk of anemia when they become pregnant mothers, causing suboptimal growth and development of the fetus, potentially causing complications in pregnancy and childbirth, as well as maternal and child death. The Blood Supplement Tablet (TTD) supplementation program for young women started in 2014 and is one of the efforts to reduce stunting. Stunting has an impact on children's growth and development both physically and cognitively, including affecting the growth and development of toddlers, less than optimal motor skills in children, and affecting learning abilities, thus affecting children's IQ. The intervention activities of the UNPAK Community Service (PKM) team on the problem of stunting were carried out on students in grades 11 and 12 of Al Falak High School, Bogor City by providing education about preventing stunting through nutritious food, anemia, blood supplements tablets (BST) containing iron (Fe)) and distribute health information media regarding stunting. It is hoped that this PKM activity will be able to increase knowledge and awareness of teenagers and expectant mothers regarding stunting.

Stunting Prevention Education for Adolescents at Al Falak High School, Bogor City Sofihidayati, Trirakhma; Rustiani, Erni; Wardatun, Sri
Jurnal Pengabdian Masyarakat Inovatif Vol. 1 No. 2 (2023): JPMI (Jurnal Pengabdian Masyarakat Inovatif)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jpmi.v1i2.94

Stunting is a condition where growth disorders occur in children which is characterized by a child's lack of height compared to children his age. Several factors cause stunting, especially in the city of Bogor, including lack of nutritional intake in the first 1000 days of life (HPK), early marriage (39 percent), teenagers suffering from anemia (3.52 percent), pregnant women with anemia (11.8 percent ), and the Covid-19 pandemic factor that occurred during the last two years. Anemia in adolescent girls (rheumatism) has an impact on health and performance at school and can be at risk of anemia when they become pregnant mothers, causing suboptimal growth and development of the fetus, potentially causing complications in pregnancy and childbirth, as well as maternal and child death. The Blood Supplement Tablet (TTD) supplementation program for young women started in 2014 and is one of the efforts to reduce stunting. Stunting has an impact on children's growth and development both physically and cognitively, including affecting the growth and development of toddlers, less than optimal motor skills in children, and affecting learning abilities, thus affecting children's IQ. The intervention activities of the UNPAK Community Service (PKM) team on the problem of stunting were carried out on students in grades 11 and 12 of Al Falak High School, Bogor City by providing education about preventing stunting through nutritious food, anemia, blood supplements tablets (BST) containing iron (Fe)) and distribute health information media regarding stunting. It is hoped that this PKM activity will be able to increase knowledge and awareness of teenagers and expectant mothers regarding stunting.

Ethanol-based solvent system for recovery antioxidant activity Centella asiatica L. Urban and its application in sleep-deprived Rats Wardatun, Sri; Sofihidayati, Trirakhma; Afifah, Nida; Juhroh, Juju
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.27277

Antioxidants have the ability to eliminate free radicals by donating electrons to oxidants. Preclinical and clinical studies show that Centella asiatica L. Urban has antioxidant activity. Ethanol was the best solvent for extracted antioxidant compounds from Centella asiatica L. Urban. The concentration of ethanol solvents effect to the compounds extracted and its antioxidant activities. The objective of study to determine ethanol based solvent systems for best recovery of antioxidant activities and in vivo antioxidant activity of the most active extract using stress induced sleep-deprived rats with glutathione (GSH) concentration parameters. Ethanol based solvent system show different recovery antioxidant activity of Centella asiatica L. Urban. Ethanol 70% had the highest recovery of antioxidant activity with an IC50 value of 76.76 ppm. Ethanol 70% Centella asiatica L. Urban extract given in sleep-deprived rats at 300 mg/kg were not significantly different in glutathione levels from those group rats that received the positive control solution (ascorbic acid). The 70% ethanol extract of C. asiatica L. Urban has the potential to ameliorate the stress induced by sleep deprivation.

Antioxidant Activity of the Herbal Combination of Black Cumin (Nigella sativa L.) with Soursop Leaves (Annona muricata L.) OR Celery (Apium graveolens L.) Wardatun, Sri; Sofihidayat, Trirakhma; Noorlaela, Ella; Agustin, Vina
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23466

Excessive free radicals in the body can cause various degenerative diseases; antioxidants can reduce the impact of free radical injury. Several plants have been tested for antioxidant activity, including black cumin (Nigella sativa L.), soursop leaves (Annona muricata L.), and celery (Apium graveolens L.). Black cumin is easy to find in several finished products on the market in Indonesia alone or in combination with other ingredients, including soursop leaves and celery. This study aimed to explore the interaction of laboratory-prepared and commercial combinations of black cumin extract with soursop or celery extract. The antioxidant activity of each extract was determined, and the combined antioxidant activity was calculated. The interactions of the combinations were identified based on the interaction factor values. The antioxidant activities were measured using DPPH (2,2-diphenyl-1-picrylhydrazyl) reagent. The results revealed nearly all exhibited strong antioxidant activity, except for black cumin–based commercial combination preparations, which demonstrated weak had antioxidant activity. Moreover, all combination extracts—laboratory made or commercial—had an IF value of 1. Conclusion: The combination of black cumin extract with soursop or celery leaf extract resulted in an antagonistic effect (IF 1) on the antioxidant ability.

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