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Preliminary Study of Physical and Chemical Stability of Polyherbal Suspensions by UV-Vis Spectrophotometry Nining, Nining; Nursal, Fith Khaira
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.45338

Abstract

Allicin, the main bioactive compound in garlic, contributes to its pharmacological effects. Monitoring the physical and chemical stability of herbal preparations is essential for ensuring product quality. This study aimed to evaluate the stability of a polyherbal suspension containing garlic, lemon, red ginger, honey, and apple cider vinegar. The suspension was assessed for physical properties (pH, viscosity, specific gravity, and particle dispersion) and chemical stability, focusing on thiosulfinate (TS) content. Measurements were taken over a period of five weeks under three different storage temperatures. TS levels were analyzed spectrophotometrically. The suspension had a specific gravity of 1.114 ± 0.002 g/mL and a pH of 3.74 ± 0.03. Both storage time and temperature significantly influenced pH, viscosity, and TS content (p<0.05), though all remained within acceptable pharmaceutical limits. TS degradation followed second-order kinetics. The polyherbal suspension demonstrated good physical stability over a five-week period. However, TS levels declined over time at all storage temperatures, indicating a trend toward reduced chemical stability.
Edukasi Pemilihan dan Penggunaan Kosmetik yang Aman pada Kalangan Remaja Armadany, Fery Indradewi; Sartinah, Ari; Mahmudah, Rifa'atul; Sawitri, Feny Eka; Andriani, Kris; Nining, Nining; Rismawati, Rismawati; Putri, Riska Damayanti
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 5, No 3 (2025): Abdira, Juli
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v5i3.856

Abstract

The development of current beauty trends influences consumer patterns in Indonesia, especially teenagers, thus encouraging the emergence of a new industry with various types of cosmetics that can be freely purchased by the wider community. This socialization was carried out with the aim of educating students to be wiser in choosing safe cosmetics. The method applied was a direct socialization method to students at SMA N 12 Kendari, providing questionnaires to see the increase in understanding after education, direct socialization and socialization carried out using leaflet media. The results obtained showed that the participants' knowledge of how to choose and use everyday cosmetics properly and safely increased. This is reflected in the average pretest value of 66.4 and the average posttest value of 89.3. The test results showed an increase in knowledge about the use of cosmetics of up to ± 22.9%. The conclusion of this activity is that socialization about safe cosmetics is very relevant and can be well received by teenagers and is able to increase teenagers' understanding of cosmetics that are safe to use, so that similar activities can be expanded to other places.
Edukasi green product berupa detergen cair ramah lingkungan berbasis lerak dan metil etil sulfonat di SMK Swadaya Global School Jakarta Timur Nining, Nining; Amalia, Anisa; Nugrahaeni, Fitria; Hariyanti, Hariyanti; Gantini, Sri Nevi
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 4 (2025): Juli
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i4.32579

Abstract

Abstrak SMK Swadaya Global School adalah salah satu Sekolah Menengah Kejuruan Farmasi di Jakarta Timur. Kegiatan ini bertujuan untuk mengedukasi siswa mengenai pembuatan detergen cair ramah lingkungan berbasis lerak dan metil etil sulfonat (MES). Detergen berbasis lerak, yang mengandung saponin, merupakan alternatif alami untuk menggantikan detergen kimiawi yang berbahaya bagi lingkungan. MES sebagai surfaktan alami dipilih karena lebih ramah lingkungan dibandingkan dengan surfaktan sintetis. Pengabdian ini dilaksanakan melalui penyampaian materi yang mengajarkan siswa cara membuat detergen cair dengan bahan alami tersebut, serta memberikan pemahaman tentang manfaat penggunaan produk berbasis alam untuk menjaga kelestarian lingkungan. Evaluasi kegiatan dilakukan melalui pengukuran tingkat pengetahuan dan pencapaian tujuan yang telah ditetapkan. Siswa menunjukkan antusiasme dan keterlibatan aktif selama kegiatan berlangsung. Hasil analisis  menunjukkan adanya peningkatan pengetahuan yang bermakna (p<0,05) antara skor rata-rata sebelum (20,00) dan setelah (93,60) kegiatan. Selain itu, observasi langsung juga mengindikasikan adanya peningkatan keterlibatan dan pemahaman yang lebih mendalam di kalangan peserta. Diharapkan, program ini dapat meningkatkan kesadaran siswa tentang pentingnya beralih ke produk ramah lingkungan dan berkontribusi pada pelestarian lingkungan. Kata kunci: : edukasi; deterjen cair; lerak; metil etil sulfonat; ramah lingkungan. Abstract SMK Swadaya Global School is a Vocational High School in Pharmacy located in East Jakarta. This activity aims to educate students on the production of eco-friendly liquid detergent made from lerak and methyl ethyl sulfonate (MES). Lerak-based detergent, which contains saponin, serves as a natural alternative to replace chemical detergents that are harmful to the environment. MES, as a natural surfactant, was chosen because it is more environmentally friendly compared to synthetic surfactants. The community service was carried out by providing material that teaches students how to make liquid detergent from these natural ingredients, while also giving them an understanding of the benefits of using nature-based products to preserve the environment. The evaluation of the activity was conducted by measuring the level of knowledge and achievement of the set goals. Students showed enthusiasm and active participation throughout the activity. The analysis results indicate a significant increase in knowledge (p<0,05) between the pre-activity average score (20.00) and post-activity score (93.60). Additionally, direct observation also showed an improvement in engagement and a deeper understanding among the participants. It is hoped that this program will raise students' awareness of the importance of switching to eco-friendly products and contribute to environmental preservation. Keywords: education; liquid detergent; lerak; methyl ethyl sulfonate; eco-friendly.
Pendidikan Obat Berbasis Sekolah Menggunakan Metode Permainan Piano (Pintar dengan Obat) Nursal, Fith Khaira; Nining, Nining
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 5 No 4 (2021): November
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v5i4.5077

Abstract

Obat merupakan sediaan yang tersusun atas satu atau lebih senyawa kimia yang memberikan khasiat dalam menjaga dan meningkatkan kesehatan masyarakat. Tetapi pada sisi lain obat bisa membahayakan kesehatan jika tidak digunakan sesuai aturan yang ditetapkan. Hal ini mengindikasikan bahwa setiap obat memiliki rasio manfaat dan resiko yang berbeda dan batasan ini menjadi tolak ukur keamanan obat. Berdasarkan fakta tersebut, diperlukan pengetahuan dan wawasan terkait obat yang dimulai dari masa pendidikan tingkat kanak-kanak hingga menengah atas untuk mempengaruhi tingkah laku penggunaan obat-obatan di lingkungan keluarga maupun masyarakat. Salah satu bentuk kegiatan yang mungkin dilakukan adalah berupa permainan dalam pendidikan obat bernama PIANO (pintar dengan obat). Permainan ini menekankan konsep pemberdayaan siswa dalam meningkatkan kemampuan memahami obat secara komprehensif sehingga pada akhirnya diharapkan terjadi perubahan sikap dan perilaku positif dalam peggunaan obat yang rasional dan sekaligus secara tidak langsung dapat mencegah penyalahgunaan obat. Hasil pengamatan kegiatan menunjukkan bahwa para siswa sangat antusias mengikuti kegiatan dan hasil analisis data menunjukkan adanya pengaruh permainan PIANO yang dilakukan dalam peningkatan pengetahuan mengenai obat.School-Based Medicine Education Using the Piano Game Method (Smart with Medicine)ABSTRACT Drugs are preparations composed of one or more chemical compounds that provide efficacy in maintaining and improving public health. But on the other hand drugs can be dangerous to health if not used according to established rules. This indicates that each drug has a different ratio of benefits and risks and this limit is a measure of drug safety. Based on these facts, knowledge and insight related to drugs are needed starting from the level of childhood education to senior high school to influence the behavior of the use of drugs in the family and community. One form of activity that might be carried out is in the form of a game in drug education called PIANO (smart with drugs). This game emphasizes the concept of empowering students in enhancing the ability to comprehend drugs comprehensively so that ultimately positive attitude and behavior changes in rational use of drugs are expected and at the same time indirectly can prevent drug abuse. The observations of the activities showed that the students were very enthusiastic about participating in the activities and the results of data analysis showed that there was an influence of the PIANO game which was done in increasing knowledge about the drug. Keywords: drug education, games, smart with medicine, piano
Profil Kemampuan Literasi Sains Siswa Pada Materi Perubahan Lingkungan Melalui Model Pembelajaran Learning Cycle Berbantu Media Padlet Nining, Nining; Hartati, Sri; Maspupah, Meti
Jurnal Pendidikan Indonesia Vol. 6 No. 9 (2025): Jurnal Pendidikan Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/japendi.v6i9.8588

Abstract

Scientific literacy is a key 21st-century competency that needs to be developed in education, particularly in relation to environmental change issues. However, the results of PISA 2022 indicate that Indonesian students’ scientific literacy achievement remains low. This study aims to analyze the effect of the learning cycle model assisted by Padlet media on high school students’ scientific literacy skills in environmental change material. The research method used was quantitative with a quasi-experimental design of the pretest-posttest control group type. The sample consisted of 60 tenth-grade students, divided into an experimental class applying the learning cycle model with Padlet and a control class using conventional learning. The data collection instrument was a scientific literacy test that had been validated and proven reliable. Data analysis was conducted using t-tests and effect size measurements. The results showed no significant difference between the experimental and control classes. This finding indicates that the integration of the learning cycle model and Padlet was less effective in improving students’ scientific literacy. Theoretically, this research reinforces the relevance of constructivist learning combined with digital media. Practically, the findings can serve as recommendations for teachers to optimize the use of technology in science learning. Future research is suggested to expand the population, include additional variables, and combine quantitative and qualitative approaches to obtain a more comprehensive understanding.