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All Journal Jurnal Riset Kesehatan Quagga Biology, Medicine, & Natural Product Chemistry PENA SAINS Journal of Natural Sciences and Mathematics Research Jurnal Ilmiah Universitas Batanghari Jambi Jurnal SOLMA JURNAL KESEHATAN PERINTIS Prosiding Seminar Nasional Multidisiplin Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Jurnal Abdimas Ilmiah Citra Bakti (JAICB) SIMBIOSA Indonesian Journal of Natural Science Education Jumat Ekonomi: Jurnal Pengabdian Masyarakat PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) BIO-CONS: Jurnal Biologi dan Konservasi Gema Kesehatan Journal of Engineering Science and Technology Management Journal for Quality in Public Health Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Kesehatan Metro Sai Wawai Jurnal Mahasiswa Kesehatan Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Cendekia Ilmiah Joong-Ki Jurnal Bioteknologi & Biosains Indonesia
Lisa Savitri
Universitas Kadiri, Jawa Timur, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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IMMUNOLOGY OF INFECTION: MECHANISM OF IMMUNE RESPONSE AND IMPLICATION FOR THERAPEUTIC Lisa Savitri; Elfred Rinaldo Kasimo; Rochmad Krissanjaya
JURNAL PENA SAINS Vol 13, No 1 (2026): Jurnal Pena Sains
Publisher : Program Studi Pendidikan IPA, Fakultas Ilmu Pendidikan, Universitas Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/jps.v13i1.29979

Abstract

Infectious diseases, caused by pathogens such as bacteria, viruses, fungi, and parasites, continue to represent a significant global health challenge. The immune system plays a pivotal role in recognizing and eliminating these pathogens, but pathogens have evolved various mechanisms to evade immune responses, resulting in chronic infections and disease progression. This review aims to explore the mechanisms of immune responses to infections, focusing on innate and adaptive immune cells, pathogen recognition, and immune evasion strategies. The review also discusses the therapeutic implications of these findings, highlighting potential targets for developing new treatments. The innate immune response, which includes pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) and NOD-like receptors (NLRs), serves as the first line of defense. In contrast, the adaptive immune response involves T cells and B cells recognizing specific antigens on pathogens. Despite the immune system's defense mechanisms, pathogens can evade immune detection through antigenic variation and suppression of immune functions. Recent research has provided new insights into immune modulation and therapeutic targets, such as enhancing the innate immune response and targeting specific immune cell subsets. Vaccines remain a critical strategy for preventing infectious diseases. Continued advancements in immunology are crucial for developing more effective interventions to control and treat infectious diseases.
Co-Authors Afrilla, Rananda Agung Dwi Wahyu Widodo Agustanti, Khalimatus Nur Eka Akbar Nur Kholis Alimansur, Moh Alves, Silvina Sandra X. Amanda, Cornelia Aminah Alfiani Ana Retnowati Anjarwati, Aprilia Antoro, Ester Lianawati Apriana, Dita Arif Budi Setiawan Besan, Emma Jayanti Cornelia Amanda Datin An Nisa Sukmawati Datin An Nisa Sukmawati Dhony Hermanto Edda, Ilda Rambu Eka Wahyuningtiyas Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo Elfred Rinaldo Kasimo, Elfred Rinaldo Elly Megasari Ester Lianawati Antoro Ester Lianawati Antoro Ester Lianawati Antoro Ester Lianawati Antoro Evi Laela Sari Fendy Prasetyawan Firdania Firdaus Rosyida Fitri, Devi Nor Freitas, João Gregório Freitas, Maria Do Carmo Da Costa Hanifah Delima Nuardani Herman Herman Herman Hilmi, Mochammad Hanif Ida Septika Wulansari Ida Septika Wulansari Ida Septika Wulansari Ida Septika Wulansari Ihsan, Kharisul Imam Agus Faizal Indrayanti, Dian Iza Dwi Muslikha Juan Vega Mahardhika Juan Vega Mahardika Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Kasimo, Elfred Khalimatus Nur Eka Agustanti Kharisma Rahmasari Kharisul Ihsan Kharisul Ihsan Kharisul Ihsan Khoirul Ngibad Kholis, Akbar Nur Kholis, Muhammad Akbar Nur Konradus Klala Mebung Laili, Nur Fahma La’ally Maula Lian Pandu Farendra Loviana, Novi Maria Do Carmo Da Costa Freitas Masyhuri, Aga Adi Mebung, Konradus Klala Megasari, Elly Meka Faizal Farabi Meri, Meri Meri, Meri Mika Tri Kumala Swandari, Mika Tri Kumala Mila Putri Daniati Mochamad Hanif Hilmi Mochamad Hanif Hilmi Mohammad Firdaus Alshol Mosse1, Yosep Muhammad Nurul Fadel Muslikha, Iza Dwi Muttaqin, Saiful Neni Probosiwi Novirma Yanti Novirma Yanti Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Nur Fahma Laili Nurul Ismillayli Ornai, Andre Mario Sequeira Alves Rasyadan Taufiq Probojati Renaldi Umbu Ndamung Kale Restyana, Anggi Restyana, Anggy Retnowati, Ana Rochmad Krissanjaya Salmasfattah, Novyananda Sanjaya, Rochmad Kris Shinta Mayasari Shinta Mayasari Sueb Sugeng Santoso Syntia Tanu Juwita Syntia Tanu Juwita Syntia Tanu Juwita Syntia Tanu Juwita Syntia Tanu Juwita Syntia Tanu Juwita Tiyas, Eka Wahyuning Tridoso Sapto A Tsamrotul Ilmi Willy Sandhika Wulansari, Ida Septika Yanti, Novirma Yosep Mosse Yosep Mosse1 yunadi, frisca dewi Yuneka Saristiana