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Uji Analgesik Ekstrak Akar Tunjuk Langit (Helminthostachys zeylanica L.) Pada Mencit Putih Jantan (Mus musculus) Fitriana, Yuli; Hendriyani, Irmatika; Wahid, Abdul Rahman; Rasmiwati, Rasmiwati; Iradhatullah, Sri Putriani; Faisal, Muhammad; Nurbaety, Baiq; Sugara, Taufan Hari
Medika: Jurnal Ilmiah Kesehatan Vol 5 No 1 (2025): Medika: Jurnal Ilmiah Kesehatan
Publisher : Universitas Nahdlatul Ulama Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69503/medika.v5i1.991

Abstract

Akar tunjuk langit (Helminthostachys zeylanica L.) merupakan salah satu tanaman yang dapat digunakan sebagai obat tradisional dimana di dalamnya terkandung senyawa-senyawa flavonoid, fenolik dan saponin yang mempunyai aktifitas biologis, diantaranya adalah efek analgetik dengan menghambat sintesis enzim siklooksigenase 2 (COX-2). Penelitian ini betujuan untuk mengetahui efek analgesik dari ekstrak Akar Tunjuk Langit (Helminthostachys zeylanica L.) pada Mencit putih jantan (Mus musculus). Penelitian ini menggunakan metode eksperimental Laboratorium dengan menggunakan 28 ekor Mencit putih jantan yang terbagi menjadi 6 kelompok yaitu kelompok kontrol positif (Asam Mefenamat), kontrol negatif (CMC- Na 0,5%), kontrol base line (minum add libitum) dan kelompok perlakuan ekstrak akar tunjuk langit dengan variasi dosis yaitu 100, 200 dan 300 mg/kgBB secara peroral, setelah 30 menit diberikan rangsangan kimia asam asetat 0,5 ml secara intraperitoneal. Pengujian dilakukan selama 3 hari. Parameter yang diamati adalah geliat mencit tiap 5 menit selama 60 menit. Data yang diperoleh dianalisis secara statistik dengan One- S Kolmogorov-Smirnov test, One Way Anova dan Post Hoc test (LSD) dengan taraf kepercayaan 95%. Hasil skrining fitokimia ekstrak akar tunjuk langit didapat bahwa pada pengujian metabolit sekunder flavonoid, saponin dan fenol menunjukkan hasil positif. Hasil penelitian menunjukkan bahwa persen daya analgetik dosis 100 mg/kgBB (25,77% ± 2,56), dosis 200 mg/kgBB (24,04% ± 0,78), dosis 300 mg/kgBB (29,18% ± 5,71) dan dosis Asam Mefenamat (58,48% ± 3,54). Dari hasil penelitian dapat disimpulkan bahwa ekstrak akar tunjuk langit dosis 300 mg/KgBB merupakan dosis terbaik sebagai analgetik dalam menurunkan nyeri pada mencit yang diinduksi asam asetat dengan nilai 29,18% ± 5,71 proteksi tetapi berbeda signifikan dengan dosis Asam Mefenamat.
Ekstrak Etanol Daun Kacang Panjang (Vigna unguiculata (L.) Walp): Kajian Morfometri Insula Pankreatika Model Tikus Diabetes: Ethanol Extract of Some Cowpea (Vigna unguiculata (L.) Walp) Leaves: Morphometry Study of Pancreatic Islet of Diabetic Rat Model Solehah, Puput Octaviani; Tarusu, Fikhta Agnesya; Tandi, Joni; Dewi, Niluh Puspita; Ratih Lintin, Gabriella Bamba; Fitriana, Yuli; Pakaya, David
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 2 (2019): (October 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.118 KB) | DOI: 10.22487/j24428744.2019.v5.i2.13934

Abstract

Diabetes is characterized by an increasing of blood levels and progressive changes in the structure of pancreatic islet of pancreas. Natural ingredients that contain antioxidants such as some cowpea leaves can be an alternative treatment for diabetes. This study aims to examine the effect of ethanol extract of some cowepea leaves (Vigna unguiculata (L.) Walp) on morphometry (perimeter and diameter) of pancreatic islet of diabetic rat models. The type of research is quasi-experimental with posttest group design. Samples were 30 male wistar rats, age 8 weeks, BW 250-300 grams, that induced by single dose of STZ 40 mg/kg BW. Rats were divided into 5 groups. Group A: normal control, Group B: negative control, Group C: positive control, Group D: DM rats with 100mg/Kg BW extract therapy, Group E: DM rats with 200mg/Kg BW extract therapy, Group F: DM rats with extract therapy 300mg/Kg BW. Blood sugar levels were measured on days 7, 14 and 21. Pancreatic tissue was prepared with 5μm thickness and stained with Hematoxylin Eosin. The sample was observed under 400x magnification microscope. The observation uses Image J software to measure the perimeter and diameter of the pancreatic insula. Data were analyzed by non-parametric Kruskal Wallis and post hoct Mann Whitney statistical tests. Blood glucose level was obtained on 21st day with the highest mean in group B (246.8±156.3) and lowest in group A (67.2 ±7.85), perimeter of pancreatic islet was significantly different (p=0.026), the diameter is significantly different (p =0.046). Ethanol extract of some cowpea (Vigna unguiculata (L.) Walp) leaves with dose of 300mg/kgBB helps to restore the blood and morphometry of pancreatic islet model of diabetic rats.
Antibacterial Activity Test of Ethanol Extract of Palm Leaves (Catharantus roseus) Against Staphylococcus aureus and Escherichia coli Bacteria Fitriana, Yuli; Iradhatullah, Sri Putriani; Sugara, Taufan Hari; Hendriyani, Irmatika; Nurbaety, Baiq; Faisal, Muhammad
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.424

Abstract

Ethanol extract of virgin palm leaves (Catharantus roseus) contains active compounds that have potential as natural antibacterial. This study aims to test the antibacterial activity of the extract against Staphylococcus aureus and Escherichia coli bacteria. The leaves of the tread are extracted using the maceration method with a 70% ethanol solvent. The extraction results showed a yield of 6.1% and the identification of compound content showed the presence of alkaloids, flavonoids, saponins, tannins, and phenols. The antibacterial test was carried out by disc diffusion method using concentrations of 60%, 80%, and 100%. Antibacterial activity was tested by calculating the resulting inhibition zones against both types of bacteria. The results showed that in Staphylococcus aureus bacteria, the concentration of 100% resulted in an inhibition zone of 11.66 mm which was classified as strong. In contrast, in Escherichia coli bacteria, the same concentration resulted in an inhibition zone of 2.66 mm which was in the weak category. This difference in effectiveness is due to the cell wall structure of gram-positive and gram-negative bacteria. The results of this study identified that ethanol extract of virgin leaves has a greater potential for gram-positive bacteria than gram-negative. The ethanol extract of virgin leaves demonstrated antibacterial activity against both Staphylococcus aureus and Escherichia coli, with stronger effects observed against S. aureus.
SASAMBO : SOSIALISASI REMAJA BEBAS NARKOBA DI SMAN 1 PRAYA Hendriyani, Irmatika; Hijriani, Nursela; Fitriana, Yuli; Faisal, Muhammad; Widodo, Ageng Ary
Journal of Community Empowerment Vol 4, No 2 (2025): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jce.v4i2.32272

Abstract

ABSTRAK                                                                Penyalahgunaan narkoba di kalangan remaja merupakan isu serius yang mengancam masa depan generasi muda. Program “SASAMBO” (Sosialisasi Remaja Bebas Narkoba) hadir sebagai upaya edukatif untuk meningkatkan kesadaran dan pengetahuan siswa mengenai bahaya narkoba. Tujuan kegiatan pengabdian ini untuk meningkatkan pengetahuan siswa dalam pencegahan bebas narkoba. Kegiatan ini dilaksanakan di SMAN 1 Praya dengan melibatkan 25 siswa anggota Palang Merah Remaja (PMR), yang telah dilaksanakan pada 16 Mei 2025. Metode yang digunakan berupa edukasi interaktif, diskusi kelompok, dan evaluasi melalui pretest dan posttest. Hasil evaluasi menunjukkan adanya peningkatan signifikan dalam pengetahuan siswa setelah mengikuti kegiatan sosialisasi. Program ini tidak hanya memberikan informasi, tetapi juga membentuk sikap preventif terhadap penyalahgunaan narkoba. Dengan demikian, SASAMBO menjadi model edukasi yang potensial untuk diterapkan di sekolah-sekolah lain sebagai langkah strategis dalam pencegahan narkoba sejak dini.Kata kunci: narkoba; remaja; sosialisasi;pendidikan kesehatan, pencegahan ABSTRACTDrug abuse among adolescents is a serious issue that threatens the future of the younger generation. The "SASAMBO" (Socialization of Drug-Free Youth) program is presented as an educational effort to increase students' awareness and knowledge about the dangers of drugs. The purpose of this community service activity is to increase students' knowledge in preventing drug-free. This activity was carried out at SMAN 1 Praya with the involvement of 26 students who are members of the Youth Red Cross (PMR), which was implemented on May 16, 2025. The methods used were interactive education, group discussions, and evaluation through pretests and posttests. The evaluation results showed a significant increase in student knowledge after participating in the socialization activity. This program not only provides information, but also forms a preventive attitude towards drug abuse. Thus, SASAMBO is a potential educational model to be implemented in other schools as a strategic step in early drug prevention. Keywords: drugs; adolescents; awareness campaign; health education; prevention
IMPROVING MOTIVATION AND LEARNING OUTCOMES OF AL-QUR'AN AND HADITH THROUGH THE STAD METHOD FOR SEVENTH GRADE STUDENTS OF MADRASAH TSANAWIYAH DARUL FATTAH Yuli Fitriana; Muhammad Azamuddin Syahapala; Sahril Dwi Pamungkas; Rido Kurnianto; Sigit Dwi Laksana
AL-MUADDIB: Jurnal Kajian Ilmu Kependidikan Vol. 7 No. 1 (2025): Januari
Publisher : LPPM STAI Muhammadiyah Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46773/muaddib.v7i1.2722

Abstract

The teaching of Al-Qur’an Hadith delivered by the 7th-grade Al-Qur’an Hadith teacher at MTs. Darul Fattah Galak Slahung Ponorogo uses a classical method. This is based on direct observations and interviews with the Al-Qur’an Hadith teacher, and it was also found that students' scores are still below the Minimum Completeness Criteria (KKM). Based on this issue, the researcher is interested in conducting research using the STAD method. The researcher aims to determine the increase in motivation and the extent of improvement in Al-Qur’an Hadith learning outcomes through the STAD method among 7th-grade students at Madrasah Tsanawiyah Darul Fattah. This study uses the Classroom Action Research (PTK) method conducted over 2 cycles, with each cycle consisting of 2 sessions. The instruments used are observations of student activities throughout the learning process from beginning to end, while test instruments are used to assess students' cognitive knowledge levels and learning outcomes. The results of activity observation as an assessment of motivation in learning in cycle I showed student activeness at 61.29%, and in cycle II it was 75.10%. There was an increase in the percentage of learning completeness from cycle I at 63.64% to cycle II at 91.18%, an increase of 27.54%. Thus, the STAD method can improve the motivation and learning outcomes of Al-Qur’an Hadith for seventh-grade students at Madrasah Tsanawiyah Darul Fattah.
HUBUNGAN DURASI SCREEN TIME TERHADAP TAJAM PENGLIHATAN SISWA KELAS 5 DAN 6 SDN MODEL TERPADU MADANI PALU sultan, bintang; Yuli Fitriana
Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran Vol. 9 No. 1 (2024): Maret
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/mtj.v9i1.1227

Abstract

Latar Belakang : Masalah penglihatan merupakan salah satu masalah kesehatan yang perlu diperhatikan dikalangan pelajar. Akibat dari masalah penglihatan ini diperlukan deteksi dini adanya penurunan visus mata pada anak usia sekolah agar dapat diketahui adakah kasus penurunan visus akibat durasi penggunaan screen time. Tujuan : Penelitian ini bertujuan untuk menganalisis hubungan durasi Screen Time terhadap tajam penglihatan siswa kelas 5 dan 6 SDN Model Terpadu Madani Palu Metode : Penelitian ini merupakan penelitian observasional yang bersifat analitik dengan menggunakan pendekatan cross-sectional. Populasi dalam penelitian ini adalah seluruh siswa kelas 5 dan 6 SDN Model Terpadu Madani Palu. Pengambilan sampel dilakukan secara total sampling. Data diolah dengan metode chi-square dengan nilai p<0,05. Hasil : Karakteristik responden berdaskan lama penggunaan screen time sebanyak 28 orang responden menggunakan media screen time <2 jam/hari (22.6%) dan 96 orang menggunakan media screen time >2 jam/hari (77.4%). Karakteristik responden berdasarkan penurunan visus terdapat 74 orang responden tidak mengalami penurunan visus dan 50 orang responden mengalami penurunan visus. Hasil uji chi-square menunjukan nilai p=0,572 (p>0,05). Kesimpulan : Tidak terdapat hubungan antara durasi screen time terhadap tajam penglihatan siswa kelas 5 dan 6 SDN Model Terpadu Madani Palu. Kata Kunci : Screen time, Tajam penglihatan, Siswa sekolah dasar
Pencegahan Kekerasan Seksual di Kampus; Meningkatkan Pengetahuan Mahasiswa tentang Kekerasan Seksual Aryuni, Muthia; Fitriana, Yuli; Lintin, Gabriella Bamba Ratih
Indonesia Berdaya Vol 4, No 4 (2023)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.2023624

Abstract

Kasus kekerasan seksual di kampus seperti halnya fenomena gunung es di mana kasus nyata jauh lebih banyak dari hanya kasus yang tampak. Salah satu penyebab maraknya kasus kekerasan seksual di lingkungan kampus karena kurangnya pemahaman mahasiswa tentang apa saja yang termasuk dalam kekerasan seksual dan apa yang harus dilakukan ketika menjadi korban. Kegiatan pengabdian kepada masyarakat ini bertujuan bertujuan untuk memberikan pemahaman terkait dengan kekerasan seksual pada mahasiswa di lingkungan kampus. Sebanyak 25 mahasiswa yang mengikuti sosialisasi ini dan diperoleh peningkatan nilai dari pretest (42,40) ke posttest (96,40). Selanjutnya hasil uji gain score diperoleh nilai rata-rata sebesar 92,95 atau 93% yang termasuk dalam kategori efektif. Kesimpulannya adalah sosialisasi pencegahan kekerasan seksual di kampus terbukti efektif untuk meningkatkan pengetahuan mahasiswa tentang pencegahan kekerasan seksual.
Tingkat Kepatuhan Ibu Hamil Mengkonsumsi Tablet Fe (ferrum) di Puskesmas Gunung Sari Nurbaety, Baiq; Hardiani, Baiq Rizki; Nopitasari, Baiq Leny; Furqani, Nur; Fitriana, Yuli; Sugara, Taufan Hari
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 5, No 1 (2024): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v5i1.21304

Abstract

Latar Belakang: Kejadian anemia atau kekurangan darah pada ibu hamil di Indonesia masih tergolong tinggi, yaitu sebanyak 48,9%. Penatalaksanaan anemia pada ibu hamil di Indonesia masih terfokus pada pemberian tablet tambah darah. Berdasarkan survei data pendahuluan di Puskesmas Gunung Sari, menunjukkan bahwa anemia ibu hamil di Puskesmas Gunung Sari pada tahun 2021 yaitu sebanyak 61 pasien, kemudian terjadi peningkatan pada tahun 2022  yaitu dengan jumlah kasus anemia sebayak 71 pasien.Tujuan : Untuk mengetahui tingkat kepatuhan Ibu hamil mengkonsumsi tablet Fe (Ferrum) di puskesmas Gunung Sari. Metode: Deskriptif Observasional dengan rancangan penelitian cross-sectional. Penelitian ini dilakukan selama periode  5 April-5 Mei 2023 yang  melibatkan 38 ibu hamil sebagai responden yang melakukan pemeriksaan di Puskesmas Gunung Sari menggunakan Kuesioner MMAS-8.Hasil: Didapatkan bahwa dari 38 responden yang memiki kepatuhan tinggi sebanyak 4 orang (10%), kepatuhan menengah 11 orang (29%) dan kepatuhan rendah 23 orang (61%). Berdasarkan skor rata-rata jawaban kuesioner terhadap tingkat kepatuhan ibu hamil dalam mengkonsumsi tablet fe di Puskesmas Gunung Sari adalah 3,71 yaitu termasuk  dalam kategori kepatuhan rendah. Kesimpulan: Tingkat kepatuhan ibu hamil mengkonsumsi tablet Fe (Ferrum) di Puskesmas Gunung Sari yaitu termasuk kategori kepatuhan rendah  sebanyak 23 orang (61%).
SOSIALISASI BAHAYA STUNTING DI KOTA PALU Ardi Munir, Muhammad; Fitriana, Yuli; Aryuni , Muthia
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 1 No. 1 (2022): Oktober 2022
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2022.v1.i1.16122

Abstract

Stunting is one of the nutritional problems currently being faced by Indonesia, especially in the area of Central Sulawesi Province. Based on research in the field, there are several problems. The identification of the problem in this study is that children are the successors of assets in the future, Indonesia, the second country with the highest incidence of stunting in the Southeast Asia region, the incidence of stunting in Central Sulawesi is still above the national average and the lack of awareness of parents, especially mothers in the dangers of stunting. for child development. Efforts are being made to overcome the stunting problem, namely by maintaining the child's diet, parenting by parents as well as sanitation and clean water. The diet in question in this case is a good and sufficient intake of energy and protein in children. Efforts made by the local government are providing additional food and vitamin A for toddlers and food supplements and blood boosters for pregnant women as a way to prevent stunting or stunting due to malnutrition. The pattern of parenting in this case, namely the knowledge of parents about stunting is very lacking. Mothers do not understand the various kinds of intake that must be met for their children. In addition to malnutrition, lack of access to clean water and poor sanitation is also a cause of stunting. On the other hand, a healthy lifestyle in the use of clean water that is applied by the community is very less noticed. This community service activity aims to provide socialization of the dangers of stunting in children. This socialization was attended by about 30 with the speaker dr. Yuli Fitriana, M.K.M. In addition to stunting socialization, the speaker also gave some tips in dealing with child stunting.
Sosialisasi dan edukasi dapatkan, gunakan, simpan dan buang (DAGUSIBU) obat di SMAN 10 Mataram Nurbaety, Baiq; Sugara, Taufan Hadi; Fitriana, Yuli; Hati, Melati Permata; Furqani, Nur
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 2 (2024): June
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i2.23935

Abstract

AbstrakPengelolaan obat di masyarakat mulai dari prosedur mendapatkan, menggunakan, menyimpan, dan membuang sisa obat tidak boleh dianggap remeh, karena jika salah melakukan pengelolaan obat, maka akan berakibat sangat fatal bagi diri kita sendiri atau konsumen obat. Pengetahuan siswa SMAN 10 Mataram masih rendah tentang penggunaan obat yang rasional. Pemahaman siswa masih kurang dalam memahami obat apa saja yang boleh dibeli tanpa resep dan harus memakai resep dokter danpengelolaan obat dirumah seperti cara menyimpan obat dengan benar dan membuang obat yang telah rusak atau kadaluarsa. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah untuk memberikan informasi terkait DAGUSIBU kepada siswa SMAN 10 Mataram. Metode yang digunakan dalam kegiatan ini adalah metode ceramah, pemberian brosur dan metode pre - post test dalam bentuk kuesioner. Subyek pengabdian kepada masyarakat ini adalah siswa SMAN 10 Mataram. Instrumen yang digunakan adalah power point, brosur dan kuesioner. Berdasarkan hasil pretest dan posttest dari kegiatan yang dilakukan dapat dilihat terjadi peningkatan pengetahuan siswa SMAN 10 Mataram tentang DAGUSIBU dari nilai rata-rata pretest peserta adalah 75% (Cukup) meningkat menjadi 87,72% (Baik) pada saat posttest. Hal ini menunjukkan bahwa para peserta dapat menerima edukasi yang diberikan dengan baik. Kata kunci: sosialisasi; edukasi; siswa; DAGUSIBU AbstractManagement of medicines in the community, starting from procedures for obtaining, using, storing and disposing of remaining medicines, should not be taken lightly, because if you mismanage medicines, it will have very fatal consequences for ourselves or medicine consumers. SMAN 10 Mataram students' knowledge is still low regarding the rational use of drugs. Students' understanding is still lacking in understanding what medicines can be purchased without a prescription and must use a doctor's prescription and manage medicines at home, such as how to store medicines properly and dispose of medicines that have been damaged or expired. This community service activity aims to provide information related to DAGUSIBU to students of SMAN 10 Mataram. The methods used in this activity are the lecture method, giving brochures and the pre-post test method in the form of a questionnaire. The subjects of this community service are students of SMAN 10 Mataram. The instruments used were power points, brochures and questionnaires. Based on the results of the pretest and posttest from the activities carried out, it can be seen that there was an increase in SMAN 10 Mataram students' knowledge about DAGUSIBU from the average pretest score of participants being 75% (Fair) increasing to 87.72% (Good) at the time of the posttest. This shows that the participants can receive the education provided well. Keywords: socialization; education; student; DAGUSIBU