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All Journal E-Jurnal Medika Udayana Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Lumbung Farmasi : Jurnal Ilmu Kefarmasian Al-Muaddib : Jurnal Kajian Ilmu Kependidikan Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Medika: Jurnal Ilmiah Kesehatan Journal of Community Empowerment Thrive Health Science Journal
Yuli Fitriana
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Uji Analgesik Ekstrak Akar Tunjuk Langit (Helminthostachys zeylanica L.) Pada Mencit Putih Jantan (Mus musculus) Fitriana, Yuli; Hendriyani, Irmatika; Wahid, Abdul Rahman; Rasmiwati, Rasmiwati; Iradhatullah, Sri Putriani; Faisal, Muhammad; Nurbaety, Baiq; Sugara, Taufan Hari
Medika: Jurnal Ilmiah Kesehatan Vol 5 No 1 (2025): Medika: Jurnal Ilmiah Kesehatan
Publisher : Universitas Nahdlatul Ulama Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69503/medika.v5i1.991

Abstract

Akar tunjuk langit (Helminthostachys zeylanica L.) merupakan salah satu tanaman yang dapat digunakan sebagai obat tradisional dimana di dalamnya terkandung senyawa-senyawa flavonoid, fenolik dan saponin yang mempunyai aktifitas biologis, diantaranya adalah efek analgetik dengan menghambat sintesis enzim siklooksigenase 2 (COX-2). Penelitian ini betujuan untuk mengetahui efek analgesik dari ekstrak Akar Tunjuk Langit (Helminthostachys zeylanica L.) pada Mencit putih jantan (Mus musculus). Penelitian ini menggunakan metode eksperimental Laboratorium dengan menggunakan 28 ekor Mencit putih jantan yang terbagi menjadi 6 kelompok yaitu kelompok kontrol positif (Asam Mefenamat), kontrol negatif (CMC- Na 0,5%), kontrol base line (minum add libitum) dan kelompok perlakuan ekstrak akar tunjuk langit dengan variasi dosis yaitu 100, 200 dan 300 mg/kgBB secara peroral, setelah 30 menit diberikan rangsangan kimia asam asetat 0,5 ml secara intraperitoneal. Pengujian dilakukan selama 3 hari. Parameter yang diamati adalah geliat mencit tiap 5 menit selama 60 menit. Data yang diperoleh dianalisis secara statistik dengan One- S Kolmogorov-Smirnov test, One Way Anova dan Post Hoc test (LSD) dengan taraf kepercayaan 95%. Hasil skrining fitokimia ekstrak akar tunjuk langit didapat bahwa pada pengujian metabolit sekunder flavonoid, saponin dan fenol menunjukkan hasil positif. Hasil penelitian menunjukkan bahwa persen daya analgetik dosis 100 mg/kgBB (25,77% ± 2,56), dosis 200 mg/kgBB (24,04% ± 0,78), dosis 300 mg/kgBB (29,18% ± 5,71) dan dosis Asam Mefenamat (58,48% ± 3,54). Dari hasil penelitian dapat disimpulkan bahwa ekstrak akar tunjuk langit dosis 300 mg/KgBB merupakan dosis terbaik sebagai analgetik dalam menurunkan nyeri pada mencit yang diinduksi asam asetat dengan nilai 29,18% ± 5,71 proteksi tetapi berbeda signifikan dengan dosis Asam Mefenamat.
Ekstrak Etanol Daun Kacang Panjang (Vigna unguiculata (L.) Walp): Kajian Morfometri Insula Pankreatika Model Tikus Diabetes: Ethanol Extract of Some Cowpea (Vigna unguiculata (L.) Walp) Leaves: Morphometry Study of Pancreatic Islet of Diabetic Rat Model Solehah, Puput Octaviani; Tarusu, Fikhta Agnesya; Tandi, Joni; Dewi, Niluh Puspita; Ratih Lintin, Gabriella Bamba; Fitriana, Yuli; Pakaya, David
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 2 (2019): (October 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.118 KB) | DOI: 10.22487/j24428744.2019.v5.i2.13934

Abstract

Diabetes is characterized by an increasing of blood levels and progressive changes in the structure of pancreatic islet of pancreas. Natural ingredients that contain antioxidants such as some cowpea leaves can be an alternative treatment for diabetes. This study aims to examine the effect of ethanol extract of some cowepea leaves (Vigna unguiculata (L.) Walp) on morphometry (perimeter and diameter) of pancreatic islet of diabetic rat models. The type of research is quasi-experimental with posttest group design. Samples were 30 male wistar rats, age 8 weeks, BW 250-300 grams, that induced by single dose of STZ 40 mg/kg BW. Rats were divided into 5 groups. Group A: normal control, Group B: negative control, Group C: positive control, Group D: DM rats with 100mg/Kg BW extract therapy, Group E: DM rats with 200mg/Kg BW extract therapy, Group F: DM rats with extract therapy 300mg/Kg BW. Blood sugar levels were measured on days 7, 14 and 21. Pancreatic tissue was prepared with 5μm thickness and stained with Hematoxylin Eosin. The sample was observed under 400x magnification microscope. The observation uses Image J software to measure the perimeter and diameter of the pancreatic insula. Data were analyzed by non-parametric Kruskal Wallis and post hoct Mann Whitney statistical tests. Blood glucose level was obtained on 21st day with the highest mean in group B (246.8±156.3) and lowest in group A (67.2 ±7.85), perimeter of pancreatic islet was significantly different (p=0.026), the diameter is significantly different (p =0.046). Ethanol extract of some cowpea (Vigna unguiculata (L.) Walp) leaves with dose of 300mg/kgBB helps to restore the blood and morphometry of pancreatic islet model of diabetic rats.
Antibacterial Activity Test of Ethanol Extract of Palm Leaves (Catharantus roseus) Against Staphylococcus aureus and Escherichia coli Bacteria Fitriana, Yuli; Iradhatullah, Sri Putriani; Sugara, Taufan Hari; Hendriyani, Irmatika; Nurbaety, Baiq; Faisal, Muhammad
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.424

Abstract

Ethanol extract of virgin palm leaves (Catharantus roseus) contains active compounds that have potential as natural antibacterial. This study aims to test the antibacterial activity of the extract against Staphylococcus aureus and Escherichia coli bacteria. The leaves of the tread are extracted using the maceration method with a 70% ethanol solvent. The extraction results showed a yield of 6.1% and the identification of compound content showed the presence of alkaloids, flavonoids, saponins, tannins, and phenols. The antibacterial test was carried out by disc diffusion method using concentrations of 60%, 80%, and 100%. Antibacterial activity was tested by calculating the resulting inhibition zones against both types of bacteria. The results showed that in Staphylococcus aureus bacteria, the concentration of 100% resulted in an inhibition zone of 11.66 mm which was classified as strong. In contrast, in Escherichia coli bacteria, the same concentration resulted in an inhibition zone of 2.66 mm which was in the weak category. This difference in effectiveness is due to the cell wall structure of gram-positive and gram-negative bacteria. The results of this study identified that ethanol extract of virgin leaves has a greater potential for gram-positive bacteria than gram-negative. The ethanol extract of virgin leaves demonstrated antibacterial activity against both Staphylococcus aureus and Escherichia coli, with stronger effects observed against S. aureus.
SASAMBO : SOSIALISASI REMAJA BEBAS NARKOBA DI SMAN 1 PRAYA Hendriyani, Irmatika; Hijriani, Nursela; Fitriana, Yuli; Faisal, Muhammad; Widodo, Ageng Ary
Journal of Community Empowerment Vol 4, No 2 (2025): September (in Progress)
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jce.v4i2.32272

Abstract

ABSTRAK                                                                Penyalahgunaan narkoba di kalangan remaja merupakan isu serius yang mengancam masa depan generasi muda. Program “SASAMBO” (Sosialisasi Remaja Bebas Narkoba) hadir sebagai upaya edukatif untuk meningkatkan kesadaran dan pengetahuan siswa mengenai bahaya narkoba. Tujuan kegiatan pengabdian ini untuk meningkatkan pengetahuan siswa dalam pencegahan bebas narkoba. Kegiatan ini dilaksanakan di SMAN 1 Praya dengan melibatkan 25 siswa anggota Palang Merah Remaja (PMR), yang telah dilaksanakan pada 16 Mei 2025. Metode yang digunakan berupa edukasi interaktif, diskusi kelompok, dan evaluasi melalui pretest dan posttest. Hasil evaluasi menunjukkan adanya peningkatan signifikan dalam pengetahuan siswa setelah mengikuti kegiatan sosialisasi. Program ini tidak hanya memberikan informasi, tetapi juga membentuk sikap preventif terhadap penyalahgunaan narkoba. Dengan demikian, SASAMBO menjadi model edukasi yang potensial untuk diterapkan di sekolah-sekolah lain sebagai langkah strategis dalam pencegahan narkoba sejak dini.Kata kunci: narkoba; remaja; sosialisasi;pendidikan kesehatan, pencegahan ABSTRACTDrug abuse among adolescents is a serious issue that threatens the future of the younger generation. The "SASAMBO" (Socialization of Drug-Free Youth) program is presented as an educational effort to increase students' awareness and knowledge about the dangers of drugs. The purpose of this community service activity is to increase students' knowledge in preventing drug-free. This activity was carried out at SMAN 1 Praya with the involvement of 26 students who are members of the Youth Red Cross (PMR), which was implemented on May 16, 2025. The methods used were interactive education, group discussions, and evaluation through pretests and posttests. The evaluation results showed a significant increase in student knowledge after participating in the socialization activity. This program not only provides information, but also forms a preventive attitude towards drug abuse. Thus, SASAMBO is a potential educational model to be implemented in other schools as a strategic step in early drug prevention. Keywords: drugs; adolescents; awareness campaign; health education; prevention
IMPROVING MOTIVATION AND LEARNING OUTCOMES OF AL-QUR'AN AND HADITH THROUGH THE STAD METHOD FOR SEVENTH GRADE STUDENTS OF MADRASAH TSANAWIYAH DARUL FATTAH Yuli Fitriana; Muhammad Azamuddin Syahapala; Sahril Dwi Pamungkas; Rido Kurnianto; Sigit Dwi Laksana
AL-MUADDIB: Jurnal Kajian Ilmu Kependidikan Vol. 7 No. 1 (2025): Januari
Publisher : LPPM STAI Muhammadiyah Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46773/muaddib.v7i1.2722

Abstract

The teaching of Al-Qur’an Hadith delivered by the 7th-grade Al-Qur’an Hadith teacher at MTs. Darul Fattah Galak Slahung Ponorogo uses a classical method. This is based on direct observations and interviews with the Al-Qur’an Hadith teacher, and it was also found that students' scores are still below the Minimum Completeness Criteria (KKM). Based on this issue, the researcher is interested in conducting research using the STAD method. The researcher aims to determine the increase in motivation and the extent of improvement in Al-Qur’an Hadith learning outcomes through the STAD method among 7th-grade students at Madrasah Tsanawiyah Darul Fattah. This study uses the Classroom Action Research (PTK) method conducted over 2 cycles, with each cycle consisting of 2 sessions. The instruments used are observations of student activities throughout the learning process from beginning to end, while test instruments are used to assess students' cognitive knowledge levels and learning outcomes. The results of activity observation as an assessment of motivation in learning in cycle I showed student activeness at 61.29%, and in cycle II it was 75.10%. There was an increase in the percentage of learning completeness from cycle I at 63.64% to cycle II at 91.18%, an increase of 27.54%. Thus, the STAD method can improve the motivation and learning outcomes of Al-Qur’an Hadith for seventh-grade students at Madrasah Tsanawiyah Darul Fattah.
Co-Authors Abdul Rahman Wahid andriyani, fatimah Anna Pradiningsih Aristo, . Badaruddin, Rahma Baiq Leny Nopitasari Baiq Lenysia Puspita Anjani Baiq Lenysia Puspita Anjani, Baiq Lenysia Puspita Baiq Nurbaety Cyntiya Rahmawati David Pakaya Dion Solli Ruruktipa Farid Indra Gunawan Fudail, Muhammad Furqani, Nur Furqoni, Nur Gabriella Bamba Ratih Lintin Gimin Gimin Hariadi Ittiqo, Dzun Hendriyani, Irmatika Iradhatullah, Sri Putriani Irmatika Hendriyani Ittiqo, Dzun Hariyadi Ittiqo, Dzun Haryadi Joni Tandi, Joni Melati Permata Hati Mohammad Fiqri Novian Affandy Muhammad Azamuddin Syahapala Muhammad Faisal Muhammad Yoland Muliadi Niluh Puspita Dewi, Niluh Puspita Ningsih, Risma Widia Nopitasari, Baiq Leny Nur Furqani Pradiningsih, Anna Puspita Sari Puspitasari, Sintha Rahmawati, Cyntiya Rais Trisiyambudi Ramadhan, Mohammad Zainul Rasmiwati, Rasmiwati Rido Kurnianto Rosdiawati, Rosdiawati Safwan Safwan Safwan Safwan, Safwan Sahril Dwi Pamungkas Sarifuddin Anwar SIGIT DWI LAKSANA Solehah, Puput Octaviani Sugara, Taufan Hadi Sumarno ' Tarusu, Fikhta Agnesya Taufan Hari Sugara Tutu, Arlin Rinni Wahid, Abdul Rahman Wahyuni, Rossa Dwi Widayatul Khairi Widodo, Ageng Ary