Maternal and infant mortality rates are one of the indicators for measuring the level of health of a country. Early detection efforts to overcome morbidity and mortality for mothers, infants and toddlers can be carried out by implementing continuous care or Continuity Of Care (COC which starts from pregnancy, childbirth, postpartum, newborns, to family planning. The purpose of this study is to be able to provide midwifery care to Mrs. O in a comprehensive and continuous manner starting from pregnancy, childbirth, postpartum, neonates and family planning. The type of descriptive research used is a case study. The research instrument uses a descriptive approach method and is documented in the form of SOAP. In this care, the author collects data through interviews, observations, physical examinations, and secondary data. This study was conducted in November 2024 - June 2025. From the results of the provision of pregnancy care, it was found that during the first visit the mother experienced nausea and vomiting, the care given was to suggest consuming warm ginger to relieve nausea. During the labor process, the mother experienced premature rupture of membranes and labor induction was carried out at the Hospital, Mrs. O gave birth spontaneously pervaginally. During the second postpartum visit, Mrs. O complained of production breast milk is not smooth and given lactation massage care and suggested consuming katuk leaves. In newborn care, all were found to be within normal limits, By Mrs. O was given HB 0 immunization, vitamin K, eye ointment and SHK. While in family planning care Mrs. O used 3-month injection birth control. It is expected that health workers provide comprehensive care to pregnant women to improve the welfare of the mother and fetus. Abstrak Angka kematian ibu dan bayi merupakan salah satu indikator untuk mengukur derajat kesehatan bagi suatu negara. Kegiatan upaya deteksi dini untuk mengatasi kesakitan maupun kematian baik ibu, bayi dan balita tersebut dapat dilakukan dengan salah satunya yaitu implementasi asuhan berkelanjutan atau Continuity Of Care (COC) yang dimulai dari masa kehamilan, persalinan, nifas, bayi baru lahir, sampai dengan KB. Tujuan penelitian ini adalah mampu memberikan asuhan kebidanan pada Ny. O secara komprehensif dan berkesinambungan mulai dari kehamilan, bersalin, nifas, neonates dan KB. Jenis penelitian deskriptif yang digunakan adalah studi kasus (case study). Dalam asuhan ini, penulis mengumpulkan data melalui wawancara, observasi, pemeriksaan fisik, dan data sekunder. Penelitian ini dilakukan pada bulan November 2024 - Juni 2025. Dari hasil pemberian asuhan kehamilan ditemukan masalah pada kunjungan pertama ibu mengalami mual muntah, asuhan yang diberikan yaitu menyarankan mengonsumsi jahe hangat untuk pereda mual. Pada proses persalinan ibu mengalami ketuban pecah dini dan dilakukan Tindakan induksi persalinan di Rumah Sakit, Ny. O melahirkan secara spontan pervaginam. Pada kunjungan nifas kedua Ny. O mengeluh produksi asi tidak lancar dan diberikan asuhan Pijat laktasi dan menyarankan mengonsumsi daun katuk. Pada asuhan bayi baru lahir didapatkan semua dalam batas normal, By Ny O diberikan imunisasi HB 0, vitamin K, salep mata dan SHK. Sedangkan pada asuhan KB Ny. O menggunakan KB suntik 3 bulan. Diharapkan tenaga kesehatan memberikan asuhan kepada ibu hamil secara komprehensif untuk meningkatkan kesejahteraan ibu dan janin.