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All Journal HAYATI Journal of Biosciences Archive of Community Health Buletin Udayana Mengabdi E-Jurnal Medika Udayana Majalah Ilmiah Fisioterapi Indonesia Indonesian Journal of Cancer Syntax Literate: Jurnal Ilmiah Indonesia Media Kesehatan Politeknik Kesehatan Makassar ISM (Intisari Sains Medis) : Jurnal Kedokteran Open Access Indonesian Journal of Medical Reviews Indonesian Journal of Cancer Journal of Global Pharma Technology Physical Therapy Journal of Indonesia Kinesiology and Physiotherapy Comprehensive Indonesian Journal of Biomedicine and Clinical Sciences
I Gusti Ayu Artini
Bagian Farmakologi Fakultas Kedokteran, Universitas Udayana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) TERHADAP Staphylococcus aureus ATCC 43300 Wuga, Kristina Supartin Monika; Jawi, I Made; Artini, I Gusti Ayu; Widhiartini, Ida Ayu Alit
E-Jurnal Medika Udayana Vol 13 No 6 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i06.P03

Abstract

Background: Kelor leaves (Moringa oleifera L.) have active compounds such as flavonoid, alkaloid, phenol, tanin, and saponin. The content of these compounds is stated to have antibacterial activity. the development of an alternative treatment of natural ingredients is needed to treat infections caused by Staphylococcus aureus bacteria, one of which is Moringa leaves (Moringa oleifera L.). Objective: To analyze the antibacterial activity from ethanol extract of moringa leaf in inhibiting of Staphylococcus aureus growth at concentrations of 25%, 50%, and 100%. Methods: The method used is a true experimental posttest-only control group in vitro. The samples of this study were divided into five groups: the positive control group (vancomycin) and the negative control group (96% ethanol solvent), with concentrations of 25%, 50%, and 100%. Result: The results proved that the extract of ethanol from moringa leaves without dilution (100% of concentration) showed about zone of inhibition against Staphylococcus aureus ATCC 43300 bacteria with an inhibition diameter of 8.4 mm and the positive control vancomycin has an inhibition zone diameter of 17.4 mm. Conclusion: Moringa leaf ethanol extract showed inhibition against bacterial growth in vitro at a concentration of 100%. Keywords: Antibacterial activity, Moringa oleifera L, Staphylococcus aureus
Aktivitas Antibakteri Ekstrak Etanol Bunga Kamboja Merah (Plumeria rubra L.) terhadap Pertumbuhan Bakteri Methicillin-resistant Staphylococcus aureus (MRSA) Diksha, I Gusti Ngurah Ariestha Satya; Artini, I Gusti Ayu; Trapika, I Gusti Made Gde Surya Chandra; Widhiartini, Ida Ayu Alit
E-Jurnal Medika Udayana Vol 13 No 5 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i05.P13

Abstract

Introduction: MRSA is an antibacterial resistance problem that requires serious treatment. The limitations of antibacterials make it difficult to treat infections. The development of alternative antibacterial is needed. Objectives: This study shows the antibacterial effect of ethanol extract of Plumeria rubra L. flowers against MRSA bacteria. Methods: This research is a true experimental research with the only post-test control group design. The Kirby-Bauer test method was used to evaluate the antibacterial activity of ethanol extract of Plumeria rubra L. flowers with concentrations of 20%, 40%, and 60% in triplicate. The test bacteria used MRSA ATCC 33591 bacteria. Antibacterial activity was assessed from the diameter of the inhibition zone formed in bacterial cultures on agar media. Results: The inhibition zone were not formed after ethanolic extract of Plumeria rubra L. flowers at various concentrations. These were not antibacterial activity shown from Plumeria rubra L. flowers extract at concentrations of 20%, 40%, and 60%. Conclusions: The ethanolic extract of Plumeria rubra L. flowers does not show antibacterial activity against MRSA bacteria. Keywords: Red frangipani flowers (Plumeria rubra L.), antibacterial activity, MRSA.
The relationship between physical activity towards anxiety and stress levels among college students Saputri, Desi Mevlana; I Gusti Ayu Artini; Gede Parta Kinandana; M. Widnyana
Physical Therapy Journal of Indonesia Vol. 4 No. 2 (2023): July-December 2023
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v4i2.146

Abstract

Background: A healthy body condition is a vital thing everyone needs, which can be achieved by doing enough physical activity. As final-year students who will end their studies in college, students will make a final project, commonly called a thesis. While finishing their thesis, students are at risk of experiencing anxiety and stress disorders. Anxiety and stress, when they occur continuously, irrationally, uncontrollably, and with increased intensity, anxiety, and stress can interfere with daily activities and lead to further mental disorders. This study aims to determine the relationship between physical activity and anxiety and stress levels in final-year students. Methods: This cross-sectional analytic study was conducted from November 2022 to February 2023. The sample was collected using a stratified random sampling technique, with 98 final-year students preparing their thesis. Physical activity was measured using the global physical activity questionnaire (GPAQ), anxiety level used the Hamilton anxiety rating scale (HARS), and stress level used the perceived stress scale (PSS). Results: Based on Spearman's rho analysis test, the results show that there was a relation between physical activity and anxiety level (p=0.000) with moderate correlation strength (r = -0.459), and there was a relation between physical activity and stress level (p=0.001) with low correlation strength (r=-0.331). Conclusion: There was a relationship between physical activity and anxiety and stress levels in final-year students of the Medical Faculty, Universitas Udayana, Bali, Indonesia. Background: A healthy body condition is a vital thing everyone needs, which can be achieved by doing enough physical activity. As final-year students who will end their studies in college, students will make a final project, commonly called a thesis. While finishing their thesis, students are at risk of experiencing anxiety and stress disorders. Anxiety and stress, when they occur continuously, irrationally, uncontrollably, and with increased intensity, anxiety, and stress can interfere with daily activities and lead to further mental disorders. This study aims to determine the relationship between physical activity and anxiety and stress levels in final-year students. Methods: This cross-sectional analytic study was conducted from November 2022 to February 2023. The sample was collected using a stratified random sampling technique, with 98 final-year students preparing their thesis. Physical activity was measured using the global physical activity questionnaire (GPAQ), anxiety level used the Hamilton anxiety rating scale (HARS), and stress level used the perceived stress scale (PSS). Results: Based on Spearman's rho analysis test, the results show that there was a relation between physical activity and anxiety level (p=0.000) with moderate correlation strength (r = -0.459), and there was a relation between physical activity and stress level (p=0.001) with low correlation strength (r=-0.331). Conclusion: There was a relationship between physical activity and anxiety and stress levels in final-year students of the Medical Faculty, Universitas Udayana, Bali, Indonesia.
The relationship between leg muscle strength and static balance in surfers Cokorda Istri Ajeng Prameswari; I Dewa Gede Alit Kamayoga; I Gusti Ayu Artini; I Made Niko Winaya
Physical Therapy Journal of Indonesia Vol. 5 No. 1 (2024): January-June 2024
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v5i1.189

Abstract

Background: Surfing is a type of water sport that involves playing on the waves by using a surfboard to maneuver on the waves. It requires good static balance and good leg muscle strength. Methods: The method used in the analytical cross-sectional study design. This research was conducted on February 25, 2023. The inclusion criteria for male surfers aged 18-25 years have ever surfed (nor in the training or learning process). According to the screening assessment, the exclusion criteria included individuals who have experienced a lower extremity injury in the last 3 months (except lacerations or injuries with open wounds). The sampling technique used was a nonprobability sampling method with a purposive sampling technique. The number of samples obtained in this research was 46 samples. Results: Data collection was carried out by measuring leg muscle strength and static balance. Leg muscle strength was measured with a leg dynamometer while static balance was measured with the Stork Standing Test. Based on the non-parametric Spearman rho analysis test, the value of p = 0.000 (p < 0.05) and the correlation coefficient r = 0.954. Conclusion: Based on the research results, it can be concluded that there was a significant relationship between leg muscle strength and static balance in surfers.
The correlation between physical activity and hypertension in menopausal women I Gusti Ayu Agung Anindya Maharani; Putu Ayu Sita Saraswati; I Gusti Ayu Artini; Anak Agung Gede Eka Septian Utama
Physical Therapy Journal of Indonesia Vol. 5 No. 1 (2024): January-June 2024
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v5i1.197

Abstract

Background: Hypertension is one of the deadliest diseases worldwide and ranks first among the most common diseases in Mengwi, Badung. Hypertension is characterized by persistently high blood pressure, with systolic blood pressure greater than or equal to 140 mmHg and diastolic blood pressure greater than or equal to 90 mmHg. Physical activity plays a crucial role in maintaining heart health. This research aimed to determine the relationship between physical activity and hypertension in menopausal women. Methods: The research used an analytical observational method with a cross-sectional approach. This research was conducted in August–November 2023 at Desa Penarungan, Mengwi, Badung, Bali. Purposive sampling was used as the sampling method, resulting in 80 samples. Physical activity was measured using the Global Physical Activity Questionnaire (GPAQ), and blood pressure was measured using a sphygmomanometer. Data was analyzed using the Spearman rank statistical test. Results: The statistical test showed a value of p=0.000 (p<0.005), indicating a significant relationship between physical activity and hypertension in menopausal women. The obtained correlation value was r=-0.479, which was negative and signified an inverse or opposite relationship with a relatively strong correlation level. This suggested that the lower the level of physical activity, the higher the degree of hypertension. Conclusion: There was a significant relationship between physical activity and hypertension in menopausal women.
Relationship between work posture and core muscle endurance with lower back disability among farmers: a cross-sectional study Kadek Novi Anggreni; Made Hendra Satria Nugraha; Ari Wibawa; I Gusti Ayu Artini
Physical Therapy Journal of Indonesia Vol. 5 No. 2 (2024): July-December 2024
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v5i2.199

Abstract

Background: Farmers rely on physical performance for their livelihood, and non-ergonomic working postures can lead to lower back pain, reducing core muscle endurance and resulting in lower back disability. This study examines the relationship between work posture and core muscle endurance with lower back disability among farmers. Methods: This research used an analytical observational design with a cross-sectional study. The sampling technique used was simple random sampling. The total sample obtained in this study was 106 participants. Data collection included posture assessment using the rapid entire body assessment (REBA), measurement of core muscle endurance using the prone bridge test, and measurement of lower back disability using the modified Oswestry disability index (MODI). The inclusion criteria for this study were farmers aged 26-45 working as farmers in Pancasari Village, Sukasada District, Buleleng Regency. Conversely, the exclusion criteria were the presence of a history of Spearman's rho and a condition of injury that limits the prone bridge test. Furthermore, the obtained data was analyzed using Spearman's rho test. Results: The non-parametric analysis of work posture on lower back disability obtained a p = 0.000 (p < 0.05) and a correlation coefficient of r = 0.849. Core muscle endurance against lower back disability obtained a value of p = 0.000 (p < 0.05) and a correlation coefficient r = -0.825, which is statistically significant that the higher the work posture score of the subject has means the higher incidence of lower back disability and also the higher of core muscle endurance the subject has, mean lower incidence of lower back disability among farmers. Conclusion: Based on the research results, it can be concluded that there is a significant relationship, with a high correlation, between work posture and core muscle endurance and the occurrence of lower back disability in farmers.
INDEKS MASSA TUBUH BERHUBUNGAN DENGAN KECEPATAN DAN KELINCAHAN ATLET Dharmajayanti, Ida Ayu Laksmi; Negara, Anak Agung Gede Angga Puspa; Artini, I Gusti Ayu
Kinetic and Physiotherapy Comprehensive Vol 2 No 3 (2023): Volume 2 No. 3 December 2023
Publisher : PT. Kesehatan Gerak Fungsi Tubuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62004/kpc.v2i3.32

Abstract

Background: Athletes are prepared to adapt their body composition to the their sports. Biomotor components such as agility and speed are certainly one of important components to support the performance of an athlete. It is necessary to know more about the suitability of body composition needed for each sport that can improve performance in athletes. This study aimed to determine the relationship between BMI, speed, and agility among athletes. Methods: This study used a literature review design to discuss the relationship between BMI, speed, and agility among athletes based on secondary data from published literature on Google Scholar and PubMed. The inclusion criteria used include: journals describing correlation between the body mass index, speed, and agility among athletes, journals published between 2015-2023. The exclusion criteria used include: excluding other articles if there are duplicates, excluding abstracts, theses, and dissertations. Results: Based on the results of a review of five studies that discussed body mass index on speed and agility in athletes, it was found that four journals stated that there were significant relationships between BMI, agility, and speed, but there was one journal which found an insignificant relationship between BMI and agility for male athletes but it was significant for female athletes. Conclusion: Agility and speed in athletes have a relationship with each BMI category. Athletes who were in the underweight BMI category would have better agility and speed compared to athletes who were in the overweight.
Synergistic Antifungal Effects of Gardenia augusta and Averrhoa bilimbi Leaf Extracts Against Candida albicans: Implications for the Treatment of Oral Candidiasis In Vitro Study Pande Putu Karina Candra; I Made Jawi; I Gusti Ayu Artini; I Gusti Made Gde Surya Chandra Trapika
Open Access Indonesian Journal of Medical Reviews Vol. 4 No. 6 (2024): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v4i6.682

Abstract

Oral candidiasis, commonly known as thrush, is a frequent fungal infection caused by Candida albicans that can lead to painful canker sores and more severe complications. Conventional treatments may have side effects, necessitating the exploration of alternative therapies. This study investigated the antifungal effects of Gardenia augusta and Averrhoa bilimbi leaf extracts against C. albicans in vitro. A post-test-only control group design was employed. Ethanolic extracts of G. augusta and A. bilimbi leaves were prepared. The antifungal activity of individual extracts and their combination (1:1 ratio) was evaluated against C. albicans using the agar well diffusion method. Ketoconazole (2%) served as the positive control, and 96% ethanol was the negative control. The diameter of inhibition zones was measured, and data were analyzed using SPSS version 26.0. Both G. augusta and A. bilimbi leaf extracts demonstrated significant antifungal activity against C. albicans, evidenced by clear inhibition zones. The combination of extracts exhibited a synergistic effect, producing a larger inhibition zone than either individual extract. In conclusion, G. augusta and A. bilimbi leaf extracts hold promise as potential alternative therapies for oral candidiasis. Their synergistic effect suggests a potential for enhanced efficacy in treating canker sores caused by C. albicans. Further research is warranted to explore their clinical application.
The role of flaxseed (Linum usitatissimum) in improving plasma lipid profiles: a literature review Marcella, Marzha; Desak Made Wihandani; I Gusti Ayu Artini
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 2 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i2.16550

Abstract

Several major risk factors contribute to cardiovascular diseases. One of these is dyslipidemia, an imbalance of plasma lipids such as total cholesterol (TC), low-density lipoprotein (LDL), triglycerides (TG), and high-density lipoprotein (HDL). While medications to lower lipids are widely used to improve lipid profiles, they have some limitations. Flaxseed is rich in ɑ-linolenic acid, phytosterols, and lignans, which can improve lipid profiles. This study aimed to review the potential effects of flaxseed on lipid metabolism. Data was gathered from research databases such as Google Scholar, PubMed, Science Direct, and Springer for the past 5 yr. About 1,527 scientific articles were found, but after eliminating duplicates and screening of title and abstract, only 45 full-text articles were assessed, with 16 selected. The result showed that ɑ-linolenic acid, phytosterols, lignans, and fibers in flaxseed improve TC, LDL, TG, and HDL through various mechanisms. In conclusion, flaxseed shows promise as a natural therapy for dyslipidemia, improving TC, LDL, VLDL, and TG levels, though HDL effects vary. Disparities are linked to demographics, form, dosage, and duration, highlighting the need for standardized research.
Penggunaan Obat Antivirus Bagi Penderita COVID – 19 di RS Universitas Udayana Tahun 2022 – 2023 Grudug, Kadek Agastya Widya Sedana; Jawi, I Made; Artini, I Gusti Ayu
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i12.55251

Abstract

COVID-19, yang disebabkan oleh virus SARS-CoV-2, pertama kali ditemukan di Wuhan, Cina, dan menjadi ancaman kesehatan global sejak awal 2020. Penelitian mengenai penggunaan obat antivirus di RS Universitas Udayana pada 2022-2023 penting untuk memberikan gambaran lengkap tentang terapi COVID-19. Penelitian ini dilakukan untuk mengetahui penggunaan obat antivirus pada penderita COVID – 19 di RS Universitas Udayana pada tahun 2022 – 2023 Penelitian ini merupakan penelitian deskriptif dengan pendekatan potong lintang (cross – sectional) untuk mengetahui gambaran penggunaan obat antivirus bagi penderita COVID – 19 di RS Universitas Udayana pada tahun 2022 - 2023. Data dikumpulkan secara retrospektif dengan melihat rekam medis pasien COVID – 19 pada tahun 2022 - 2023 di RS Universitas Udayana setelah mendapatkan izin dari pihak – pihak yang bersangkutan. Kemudian data diolah dengan software IBM SPSS 26. Hasil penelitian menunjukan dari total 101 pasien COVID-19, mayoritas adalah laki-laki dengan persentase 50,5%, dan kelompok usia 19-35 tahun merupakan yang paling banyak terpapar; sekitar 63,4% pasien memiliki komorbid, dan mayoritas pasien mengalami derajat keparahan rendah (73,3%); dalam penanganan, Favipiravir adalah obat antivirus yang paling sering digunakan. Dari total 101 pasien COVID-19, laki-laki lebih dominan dan kelompok usia dewasa muda hingga paruh baya, terutama 19-35 tahun, adalah yang paling banyak terinfeksi. Sebagian besar pasien memiliki komorbid, yang memperburuk kondisi mereka. Meskipun mayoritas pasien mengalami derajat keparahan rendah, Favipiravir merupakan obat antivirus utama yang digunakan dalam terapi,
Co-Authors Agung Nova Mahendra Agung Wiwiek Indrayani Anak Agung Gede Eka Septian Utama Ari Wibawa Arina Papita Simanungkalit Cokorda Istri Ajeng Prameswari Desak Ketut Ernawati Desak Made Wihandani Dewi, Anak Ayu Nyoman Trisna Narta Dharmajayanti, Ida Ayu Laksmi Diksha, I Gusti Ngurah Ariestha Satya Dinda Paramaningtyas Sudibya Fatimah S, Sitti Febrina, Jessica Gede Denny Wiradarma Gede Parta Kinandana Grudug, Kadek Agastya Widya Sedana I Dewa Gede Alit Kamayoga I Gusti Ayu Agung Anindya Maharani I Gusti Ayu Eka Arirahmayanti I Gusti Made Aman I Gusti Made Gde Surya Chandra Trapika I Kadek Dwi Putra Diatmika I Made Jawi I MADE MULIARTA . I Made Niko Winaya I Nyoman Adi Putra I Wayan Adi Pranata I Wayan Juli Sumadi I.A.A. Widhiartini Ida Ayu Citra Ratnasari Ida Ayu Eka Pradnya Paramita Dewi Paramita Dewi Ida Ayu Ika Wahyuniari Kadek Meitri Ariyantini Kadek Novi Anggreni Kartiga Silvaraju M Widnyana Made Aditya Prawira Arthawan Made Ayu Nadine Indira Surya Made Cindy Widya Murthi Made Hendra Satria Nugraha Made Satria Ambarsika Made Virgo Baharirama Marcella, Marzha Nabila Putri Rachmawati Negara, Anak Agung Gede Angga Puspa Ni Komang Artini Yanti Ni Komang Ayu Juni Antari Ni Luh Nopi Andayani Ni Made Linawati Ni Putu Devi Purnamayanti Ni Wayan Mira Resdiani Ni Wayan Tianing Nila Wahyuni Pande Putu Karina Candra Putu Aditya Mahardika Putu Ayu Sita Saraswati Putu Ayunia Laksmita Putu Diah Saraswati Rahayu Putu Yunita Primasari Rizki Mega Aprilia Saputri, Desi Mevlana Theresia Fitri Hakna Sihombing Trapika, I Gusti Made Gde Surya Chandra Winaya, I Made Nico Wuga, Kristina Supartin Monika