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All Journal Jurnal Berkala Epidemiologi JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) The Indonesian Journal of Public Health The Indonesian Journal of Occupational Safety and Health JURNAL KESEHATAN LINGKUNGAN: Jurnal dan Aplikasi Teknik Kesehatan Lingkungan Health Notions Journal of Health Science and Prevention Jurnal Kesehatan Jurnal Layanan Masyarakat (Journal of Public Service) Indian Journal of Forensic Medicine & Toxicology Jurnal Pengabdian Masyarakat (ABDIRA) Media Publikasi Promosi Kesehatan Indonesia (MPPKI) ABDIMAYUDA: Indonesian Journal of Community Empowerment for Health Journal of Health Management and Pharmacy Exploration (JOHMPE) Blantika : Multidisciplinary Journal Jurnal Pengabdian Masyarakat dan Riset Pendidikan
Soedjajadi Keman
Departemen Kesehatan Lingkungan Fakultas Kesehatan Masyarakat Universitas Airlangga Kampus C Mulyorejo, Surabaya, Jawa Timur 60115
Aerospace Engineering Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Health Notions

 1 
Expression of Catalase and Malondialdehyde Levels in Silicon Dioxyde-exposed Lung Tissue of Mice Treated with Moringa oleifera Leaves Extract Kusmiyati, Kusmiyati; Keman, Soedjajadi; Amin, Muhammad; Suwarno, Suwarno
Health Notions Vol 2 No 3 (2018): March 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (616.261 KB)

Abstract

Silica particle such as silicon dioxide (SiO2), is considered as a hazardous and cytotoxic particle. Silica particle exposure leads to oxidative stress in lung tissue. Moringa oleifera is a plant with potential antioxidant compounds. Therefore the aim of this study was to analyze the effect of M. oleifera leaves extract (MLE) on expression of catalase enzyme and malondialdehyde (MDA) levels in lung tissue of mice exposed to silica particles. This study was an experimental study with randomized posttest-only control group design using 30 male Balb/c strain mice, 8-10 weeks of age, 20-30 g body weight (BW), which were randomly divided into five groups. Group 1 was the negative control group, group 2 was exposed to SiO2 particle and set as the positive control group, group 3 was treated with MLE 2 mg/20 g BW, group 4 was treated with MLE 5 mg/20 g BW, and group 5 was treated with MLE 8 mg/20 g BW. After 90 days, mice were sacrificed by cervical dislocation and the lung tissues were examined.  Study results showed that expression of catalase in lung tissues of MLE-treated group was higher than that of positive control group, but not statistically significant. There was a significant difference of MDA level in lung tissue among groups. MDA level of groups treated with MLE 2 mg/20 g BW and 5 mg/20 g BW was lower than that of control group, while group treated with MLE 8 mg/20 g BW showed higher MDA level than control group (One Way ANOVA, p<0.05). It is concluded that administration of MLE indicates to prevent SiO2 inducedoxidative stress in lung tissue of Balb/c mice.    Keywords: Antioxidant, Catalase, Malondialdehyde, Moringa oleifera, Silicon dioxyde 
Influence of Student Behavior on Hepatitis A Incidence and Prevalence in Islamic Boarding School “Sidogiri” Secaria, Bhirawa Odie Prino; Sulistyorini, Lilis; Keman, Soedjajadi
Health Notions Vol 2 No 6 (2018): June 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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abstract
Expression of Catalase and Malondialdehyde Levels in Silicon Dioxyde-exposed Lung Tissue of Mice Treated with Moringa oleifera Leaves Extract Kusmiyati Kusmiyati; Soedjajadi Keman; Muhammad Amin; Suwarno Suwarno
Health Notions Vol 2, No 3 (2018): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (616.261 KB) | DOI: 10.33846/hn.v2i3.146

Abstract

Silica particle such as silicon dioxide (SiO2), is considered as a hazardous and cytotoxic particle. Silica particle exposure leads to oxidative stress in lung tissue. Moringa oleifera is a plant with potential antioxidant compounds. Therefore the aim of this study was to analyze the effect of M. oleifera leaves extract (MLE) on expression of catalase enzyme and malondialdehyde (MDA) levels in lung tissue of mice exposed to silica particles. This study was an experimental study with randomized posttest-only control group design using 30 male Balb/c strain mice, 8-10 weeks of age, 20-30 g body weight (BW), which were randomly divided into five groups. Group 1 was the negative control group, group 2 was exposed to SiO2 particle and set as the positive control group, group 3 was treated with MLE 2 mg/20 g BW, group 4 was treated with MLE 5 mg/20 g BW, and group 5 was treated with MLE 8 mg/20 g BW. After 90 days, mice were sacrificed by cervical dislocation and the lung tissues were examined. Study results showed that expression of catalase in lung tissues of MLE-treated group was higher than that of positive control group, but not statistically significant. There was a significant difference of MDA level in lung tissue among groups. MDA level of groups treated with MLE 2 mg/20 g BW and 5 mg/20 g BW was lower than that of control group, while group treated with MLE 8 mg/20 g BW showed higher MDA level than control group (One Way ANOVA, p<0.05). It is concluded that administration of MLE indicates to prevent SiO2 inducedoxidative stress in lung tissue of Balb/c mice.Keywords: Antioxidant, Catalase, Malondialdehyde, Moringa oleifera, Silicon dioxyde
Influence of Student Behavior on Hepatitis A Incidence and Prevalence in Islamic Boarding School “Sidogiri” Bhirawa Odie Prino Secaria; Lilis Sulistyorini; Soedjajadi Keman
Health Notions Vol 2, No 6 (2018): June
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn20614

Abstract

Islamic boarding school Sidogiri is one of the school which has 8.400 male students. The sanitary conditions of Islamic boarding school are closely related to the contagion rate of contagious environment-based diseases, one of which is Hepatitis A. Islamic boarding school Sidogiri experiencing Hepatitis A outbreak in 2014, attacked as many as 111 students. This research was conducted to find out the correlation between students behavior (knowledge, attitude, and action) with incident and prevalence of Hepatitis A. The type of research was analytic observational research by analyzing behavior with the occurrence of Hepatitis A (IgG and IgM). The study was conducted in Islamic boarding school Sidogiri Kraton subdistrict in Pasuruan district from July 2017 until March 2018. The population in this study were all students in Islamic boarding school Sidogiri. Sample selection was done randomly so that got sample amount 38 people. The result of this research mentioned that attitude and action factor have significant influence to the occurrence of hepatitis A (IgG) with p-value equal to 0.017. The lower the attitudes and actions, the higher the prevalence of IgG. While the action factor has a significant effect on the incidence of Hepatitis A (IgM) with p value of 0.001. The lower the action, the higher the prevalence of IgM. Socialization, promotion and health education needs to be done to reduce the risk of contracting hepatitis A. Keywords: Islamic boarding school; students behaviour; hepatistis A; IgG; IgM
Co-Authors . Suwarno A. Mirasa, Yudied Acknes Leonita Aditya Sukma Pawitra Aditya Sukma Prawira Afriani, Novi Dian Agustin, Avita Fitri Aini Fadlila Alif, Achmad Arfiani, Novi Ari Rahmawati Putri Avita Fitri Agustin Ayu Wulandari Bhirawa Odie Prino Secaria Corie Indria Prasasti Corie Indria Prasasti Corie Indria Prasasti Dedy Suprayogi Desi Listianingsih Eka Saul Manuel Endang Dwiyanti Eny Rohmawati Fadilatus Sukma Ika Noviarmi Fakhira, Amira Dhisa Farida Giyartika Fitrotuz Zahroh Franky Darmawan Hamzah, Firdaus Mohamad Hana’ Izdihar Hari Basuki Notobroto Herwin. A. Hi. Adam Izdihar, Hana’ J Mukono J. Mukono J.Mukono Kahar Kahar Kencana, Yulfa Tiara Khuliyah Candraning Diyanah Kusmiyati Kusmiyati Kusmiyati Kusmiyati Kusuma Scorpia Lestari Kusuma Scorpia Lestari Kusuma Scorpia Lestari, Kusuma Scorpia Kusuma Wardani, Ratnaningtyas Wahyu Leli Indahwati Lestari, Kusuma Lilis Sulistyorini Lusno, Muhammad M Yusuf Alamudi Mika Vernicia Humairo Moch. Irfan Hadi Muhammad Amin Muhammad Amin Muhammad Farid Dimjati Lusno Muhashonah, Izzuki Mukono, Jojok Novi Dian Arfiani Nur Hakim, Luqman Nuzulul Kusuma Putri Nuzulul Kusuma Putri R Azizah R. Azizah R. Azizah R. Azizah Azizah R.Azizah Ramadhani, Gina Salsabila Rania Ichwana Wicaksono Ratna Dwi Puji Astuti Ratnaningtyas Wahyu Kusuma Wardani Retno Adriyani Ririh Yudhastuti Rizaldi, M Addin Rohmah, Shofiyatur RR. Ella Evrita Hestiandari Saadatuddaroini Saadatuddaroini Saliza Binti Mohd Elias Secaria, Bhirawa Odie Prino Shita Addina Sofiyan Sofiyan Sudarmaji SUDARMAJI SUDARMAJI Sudarmaji Sudarmaji Suwarno Suwarno Taufik Ikhtiar, Erwan Ursula Yesi Gusti Ayuputri Wardani, Ratnaningtyas Winata, Vina Pandi Ananta Yudied Agung Mirasa Yudied Agung Mirasa Yulfa Tiara Kencana Zida Husnina Zida Husnina