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All Journal Jurnal Ilmu Dasar Jurnal Sains Dasar Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat PROSIDING SEMINAR KIMIA KOVALEN: Jurnal Riset Kimia Jurnal Kimia Mulawarman Science and Technology Indonesia JURNAL ATOMIK Jurnal Sustainable: Jurnal Hasil Penelitian dan Industri Terapan Bisma: Jurnal Bisnis dan Manajemen Spektrum Analisis Kebijakan Pendidikan BISMA (Bisnis dan Manajemen) VALUE: Journal of Business Studies Kubis
Chairul Saleh
Jurusan Kimia Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Environmental Science Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Physics Social Sciences Other

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Journal : PROSIDING SEMINAR KIMIA

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REVIEW ARTIKEL: SKIRINING FITOKIMIA DAN AKTIVITAS FARMAKOLOGIS TANAMAN KRATOM (Mitragyna speciosa Korth) Aina, Nur; Saleh, Chairul; Marliana, Eva
PROSIDING SEMINAR KIMIA Vol 3 No 1 (2024): Prosiding SNK 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Kratom (Mitragyna speciosa korth) is one of the plants found in forest areas in Indonesia. Phytochemical screening and pharmacological activity of kratom plants (Mitragyna speciosa Korth) have been conducted. Some studies show kratom plants contain secondary metabolites, namely alkaloids, flavonoids, saponins, triterpenoids, tannins and terpenoid-steroids. Literature studies show kratom leaves have strong antioxidant activity with IC50 values <50 ppm. Kratom leaves have antinonceptive activity in the dichloromethane fraction at doses of 70 mg/kgBB (51%), 140 mg/kgBB (81%) and 280 mg/kgBB (86%). Antimicrobial activity against staphylococcuc pidermidis bacteria with a concentration of 5% (7.23 mm) 10% (10.50 mm), 15% (11.78 mm), 20% (12.63 mm) and 25% (13.69 mm). Stems and roots of kratom plants have antibacterial activity against propionibacterium acnes bacteria, stem concentration 5% (5.71 mm ± 0.40), 10% (6.75 mm ± 0.26) and 15% (6.78mm ± 0.29), on roots 5% (5.4 mm ± 0.12), 10% (5.8 ± 0.08) and 15% (6.21 mm ± 0.36). Anti-inflammatory activity with a dose of kratom extract 0.5 mg/grBB (46.37 mm ± 10.04), 1 mg/grBB (32.33 mm ± 11.24), 2mg/grBB (26.69 mm ± 6.57). Acute toxicity test in the reflux method LC50 value of 71.08 ppm while the maceration method LC50 value of 143, 50 the results shown are included in the toxic category. Keywords: Mitragyna speciosa korth, Mitragyna, phytochemical screening
REVIEW ARTIKEL: IDENTIFIKASI FITOKIMIA, POTENSI AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS DAUN BALAKACIDA (Chromolaena odorata L.) Marsella, Virna Rindra; Saleh, Chairul
PROSIDING SEMINAR KIMIA Vol 3 No 1 (2024): Prosiding SNK 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Balakacida is a plant that grows in open areas and thrives in plantations, so this plant is often referred to as a weed. This plant is often used as a live pharmaceutical plant to cure several diseases. Various studies on the phytochemical content of Balakacida plants have been conducted. Phytochemical identification of Balakacida plants shows that Balakacida plants contain phytochemical aglycones, flavonoids, terpenoids, essential oils, alkaloids, saponins, tannins and steroids. Literature studies show that Balakacida leaves have toxicity activity shown in the LC50 value. The LC50 values obtained in the crude extract, n-hexane fraction, ethyl acetate are 2.88 ppm, 8.12 ppm and 6.86 ppm respectively. It is known that Balakacida plants have high antioxidant content, this is influenced by its high flavonoid levels. In Balakacida leaf extract, having an IC50 value of 23.4 µg/mL. So that researchers can conclude that Balakacida leaf extract has phytochemical content of aglycone groups, flavonoids, terpenoids, essential oils, alkaloids, saponins, tannins and steroids, with very strong toxicity and antioxidant activity. Keywords: Antioxidant, Balakacida, phytochemical identification, toxicity
Co-Authors Agung Prasetyo Agus Priono Ajeng Kartini Akbar, Fath Ali Alimuddin - Alimuddin - Alimuddin Alimuddin Alpina Nora Kaban Ami, Suyatmi Ana Arum Sari Ana Arum Sari, Ana Arum Ardiansyah - Ardiansyah - Arifah, Churniati Nur Arwidhiah, Nanda Ary Rizki Darmawi Ary Rizki Darmawi, Ary Rizki Aulia Husna Rabbani Azhar Seli Apriani Azhar Seli Apriani, Azhar Seli Barikah, Kuni Z. Bastara, Dimas B. Bohari Yusuf Bonita Tahir Daniel Daniel - Daniel - Daniel -, Daniel Daniel Daniel Daniel Daniel Daniel Daniel Daniel Tarigan Deni Karisnawati Dessy Karlina Desy Ridho Rahayu Dewi, Camelia Eugenia Djihan Ryn Pratiwi, Djihan Ryn Dwi Fitria Sari Dwi Perwitasari Wiryaningtyas, Dwi Perwitasari Eci Endang Sinulingga Eko Haryanto Eko Haryanto Elean, Samuel Elok Sri Utami Ema Desia Prajitiasari Erwin - Erwin - Erwin E Erwin Erwin Erwin Erwin Erwin Erwin Eva Marliana, Eva Fadillah, Fahmi Farhany, Farhany Farida Amir Farida Amir, Farida Fauziah, Nadiya Ayu Hairani, Rita Hammamiyah, Ulinnuha Hamsiana - Hevin Muttaqin Husnul Chatimah Indra Masmur Izkia Mawaddah Jaya, Edi Novian Juwita, Retno Karolina Sinukaban Ketut Indraningrat KHOIRUN NISAK Krishnabudi, N. G Kusumaningrum, Indah Yulia Kusumawardani, Niken Lembang, Darmita Tiku Lilik Farida Lutfiana Devi Kurnia M.Riza Agus Pramana Magdaleni Agustina Rahayu Magdaleni, Agustina R. Magdaleni, Agustina Rahayu Marsella, Virna Rindra Masmur, Hestina Medi Hendra, Medi Mira Wahyuni Mira Wahyuni, Mira Muhammad Rivai Mujahidin1, Muhamad Mustafidah - Mustafidah -, Mustafidah Mutma Inna Nadhirah - Natalia, Princessa Noor Hindryawati, Noor Nugraheni, Dyah Ayu Nur Aina Nur Aini Haryati Nuranda, Apri Nyoman Gede Krishnabudi Oman, Aries Panannangan, Josua K. Pangaribuan, Fransiscus X. Rico Pindan, Neli Peni Prabowo, Rachmat Prabowo, Rachmat Udhi Pratiwi, Ricka Indria Precelia, Sari Clara Priyanto, Fajar Wahyu Purnamie Titisari Purwanti, Gettik Andri Puspita, Leonita Dwi Puspitasari, Intan Dessy Rachman, Ferry Aditya Rahmat Gunawan RAHMAT GUNAWAN Ramadhan, Aulia Ravensca, Irene Rindawati, Novi Ritbey Ruga Ritson Purba, Ritson Rochman, Mayasari Azhari Rohmat Hidayat Rohmat Hidayat Rudi Kartika, Rudi Ruga, Ritbey Ryn Pratiwi, Djihan Saibun Sitorus Sandra, Putri Ayu Sanjaya, I Made Duwi Septi Roro Liniawati Shadrina, Alyani Nur Simatupang, Eliene Br. Siti Maimunah Sitompul, Citra Uli Soma, Yolanda V. A Subagyono, RR Dirgarini Julia Nurlianti Subur P Pasaribu Sulistiawati, Iqlimah Sulistiyawati, Rizki Ramadhani Sumarni, Feni Sunardi Sunardi Susanto, Arnis Budi Syafriyanti, Yuly T, Nurnaningsi Theresia Susetyarsi Tri Novianti Tria Annisa Rizky Tria Apriliana, Tria Ulfa Mutia Ulfa Mutia, Ulfa Ulfa, Yulyanti Sartika Utami, Diandra Weningtyas Wahyu Pratama Wajdie, Farid Winni Astuti Winni Astuti, Winni Yuli Yana