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Antimicrobial Properties of Eco Enzyme: A Literature Review Pande Ayu Naya Kasih Permatananda; I Gde Suranaya Pandit; Putu Nita Cahyawati; Anak Agung Sri Agung Aryastuti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 6 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i6.831

Abstract

Background: In surgical medicine, the use of antimicrobials is very important. The use of antimicrobials or antibiotics is used at the time before surgery as prophylaxis, intraoperative, and postoperative. The prevention of some bacterial infections is imperative. The latest research is constantly evolving toward the use of antibiotics, which follows an increasingly resistant antibiotic trend. One of the advancements in the use of antimicrobials is eco enzymes. Methods: The literatures reviewed in our study was gathered from PubMed and Google Scholar. The advanced search was conducted on PubMed with the keywords used ("Eco enzyme" AND "antimicrobial" AND "activity" OR "Antibiotics"; "Mechanism" OR "Nature"). The advanced search was also conducted on Google Scholar with all of the words "antimicrobial activity of eco enzyme". We reviewed the articles cited within the literature to broaden the search results. Results: Some materials used as eco enzymes in this literature review include Carica papaya L., Annona muricata L., Azadirachta indica Cymbopogon winterianus, Ananas comosus, citrus aurantium, etc. Bioactive substances that play a role in microbacterial activity are flavonoids, tannins, saponins, pH, and lactic acids through mechanisms inhibiting nucleic acid synthesis, inhibit cell membrane function, inhibiting energy metabolism of bacteria, and cross-bacterial cell membranes because of the pH gradient, leading to the disruption of cellular metabolic activities of bacterias. Conclusion: Eco enzymes have been shown to have antimicrobial abilities.
MITIGASI BENCANA, KESEHATAN LINGKUNGAN, DAN PENGENDALIAN VEKTOR PENYAKIT PADA KELOMPOK WARGA TERDAMPAK BANJIR BANDANG DI DESA PENYARINGAN, JEMBRANA Pande Ayu Naya Kasih Permatananda; Ni Wayan Rusni; I Gde Suranaya Pandit; Anak Agung Sri Agung Aryastuti
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Volume 4 Nomor 3 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i3.17310

Abstract

Intensitas hujan yang tinggi selama penghujung tahun 2022 pada hampir seluruh kawasan di Bali, terutama di Bali Barat, menyebabkan munculnya bencana banjir bandang di sejumlah desa di Kabupatan Jembrana, salah satunya adalah Desa Penyaringan. Desa Penyaringan Kecamatan Mendoyo Kabupaten Jembrana merupakan daerah dengan tingkat kerusakan paling parah akibat bencana banjir bandang di bulan Oktober 2022 tersebut karena berada di sepanjang daerah aliran sungai Biluk Poh. Pemulihan infrastructure yang rusak akibat bencana banjir bandang di Desa Penyaringan sudah dilakukan oleh pemerintah pusat maupun daerah. Sehingga solusi yang ditawarkan kepada mitra meliputi edukasi mitigasi bencana, sesi psychohealing, reboisasi hulu sungai biluk poh, pembuatan lubang biopori, edukasi vector borne disease, serta pemanfatan lahan pekarangan untuk budidaya tanaman pengendalian vektor penyakit. Pelaksanaan kegiatan ini telah memenuhi 3 indikator dalam evaluasi, yaitu evaluasi input berupa terselenggaranya kegiatan sesuai waktu yang dijadwalkan dengan jumlah peserta sesuai yang diharapkan. Indikator outcome dinilai melalui antusiasme peserta juga sangat tinggi ditunjukkan dengan interaksi yang baik selama mengikuti kegiatan. Indikator output yaitu pengetahuan juga mengalami peningkatan yang signifikan dan penurunan kecemasan setelah mengikuti sesi psychohealing, dan tersalurkannya bantuan kepada mitra. Kegiatan ini diharapkan mampu mengurangi dampak banjir bandang yang dialami mitra dan membantu mitra untuk meningkatkan kewaspadaan terhadap bencana banjir yang sering terjadi di daerah tersebut.
Pencegahan Stunting Pada Kelompok Posyandu Desa Bayung Gede, Kintamani Pande Ayu Naya Kasih Permatananda; I Gde Suranaya Pandit; Ni Putu Indah Kusumadewi Riandra
Journal Of Human And Education (JAHE) Vol. 3 No. 2 (2023): Journal Of Human And Education (JAHE)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jh.v3i2.219

Abstract

Stunting merupakan kondisi anak mengalami gangguan pertumbuhan, sehingga tinggi badan tidak sesuai dengan rata-rata anak seusianya akibat kekurangan asupan gizi dalam waktu yang lama. Desa Bayung Gede merupakan salah satu desa di Kecamatan Kintamani Bangli dengan angka stunting yang cukup tinggi. Kegiatan pengabdian masyarakat ini ditujukan pada kader posyandu Desa Bayung Gede untuk meningkatkan pengetahuan dan keterampilan dalam rangka pencegahan stunting. Materi diberikan berupa penyuluhan, pelatihan, dan pendampingan mengenai stunting, dampak stunting pada tumbuh kembang anak, cara mendeteksi stunting, dan memberi keputusan. Kegiatan ini diikuti oleh 15 kader posyandu di Desa Bayung Gede yang didominasi pria. Evaluasi pretest-posttest didapatkan terdapat peningkatan pengetahuan sebesar 62,66 dan bermakna signifikan setelah diuji dengan statistik. Sehingga dapat disimpulkan kegiatan ini dapat memberi pengetahuan dan keterampilan kader posyandu Desa Bayung Gede dalam mendeteksi stunting sebagai langkah awal pencegahan stunting.
From Tradition to Translation: A Systematic Review on the Pharmacological Actions of Eugenol Extracted from Ocimum Plants in Oxidative Stress, Inflammation, and Diabetes Mellitus Permatananda, Pande Ayu Naya Kasih; I Wayan Putu Sutirta Yasa; I Wayan Sumardika; Made Ratna Saraswati; I Gde Suranaya Pandit
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 6 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i6.1302

Abstract

Background: Ocimum species, commonly known as basil, have a rich history in traditional medicine for various ailments. Eugenol, a primary bioactive compound found in several Ocimum species, has garnered significant scientific attention for its potential therapeutic properties. This systematic review aimed to comprehensively evaluate the pharmacological actions of eugenol extracted from Ocimum plants in the context of oxidative stress, inflammation, and diabetes mellitus. Methods: A systematic literature search was conducted across major scientific databases for studies published between 2013 and 2024 that investigated the effects of eugenol derived from Ocimum plants on oxidative stress, inflammation, and diabetes mellitus. The search strategy included keywords such as "eugenol," "Ocimum," "antioxidant," "anti-inflammatory," and "antidiabetic." Inclusion criteria for studies involving in vitro, in vivo, and clinical studies that specifically examined the pharmacological actions of eugenol extracted from Ocimum species in the aforementioned conditions. Data on study design, intervention, outcomes, and key findings were extracted and synthesized narratively. Results: The review identified ten key studies that met the inclusion criteria. These studies collectively suggested that eugenol extracted from Ocimum plants exhibited significant antioxidant activity by scavenging free radicals and enhancing endogenous antioxidant enzymes. Furthermore, eugenol demonstrated anti-inflammatory effects by modulating pro-inflammatory cytokines and inhibiting key inflammatory pathways such as NF-κB and COX. In the context of diabetes mellitus, studies indicated that eugenol could improve glucose metabolism by enhancing insulin sensitivity, protecting pancreatic beta cells, and inhibiting carbohydrate metabolizing enzymes. Conclusion: This systematic review provided a comprehensive overview of the pharmacological actions of eugenol extracted from Ocimum plants in mitigating oxidative stress, inflammation, and diabetes mellitus. The findings from the included studies supported the traditional uses of Ocimum species and highlighted the therapeutic potential of eugenol as a natural agent in managing these conditions. Further well-designed clinical trials are warranted to validate these preclinical findings and translate them into clinical applications.
Program Pengabdian Masyarakat dalam Rangka Pencegahan Kecelakaan Rumah Tangga pada Anak di Desa Bayung Gede, Kintamani : Pengabdian Pande Ayu Naya Kasih Permatananda; I Gde Suranaya Pandit; Desak Putu Citra Udiyani; Putu Nita Cahyawati; Asri Lestarini
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 3 No. 4 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 3 Nomor 4 (April 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v3i4.1119

Abstract

Anak-anak merupakan korban tersering dari kecelakaan rumah tangga, yang sebagian besar terjadi pada anak-anak yang hidup di negara miskin dan berkembang. Pencegahan dan kontrol kecelakaan rumah tangga pada anak di bawah 5 tahun disebutkan cukup efektif dalam mehurunkan mortalitas akibat kecelakaan. Program pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan keluarga dalam melakukan pencegahan kecelakaan rumah tangga. Metode transfer ilmu pengetahuan yang digunakan dalam kegiatan ini meliputi penyuluhan kelas besar pada perwakilan keluarga di Desa Bayung Gede dan pendampingan keluarga kepada 5 keluarga binaan yang terpilih. Evaluasi dilakukan sebanyak 2 kali, yaitu setelah penyuluhan kelas besar berupa pertanyaan pilihan ganda, dan setelah pendampingan keluarga berupa observasi checklist perilaku ya atau tidak. Hasil program pengabdian masyarakat di Desa Bayung Gede ini cukup baik. Penyuluhan kelas besar mampu meningkatkan pemahaman peserta mengenai pencegahan kecelakaan rumah tangga pada anak. Pendampingan kepada lima keluarga binaan berhasil mengidentifikasi perilaku-perilaku yang keliru dan kembali memberi penekanan untuk penerapan perilaku preventif yang lebih optimal. Ke depan, diharapkan adanya langkah yang kolaboratif dan berkesinambungan untuk dapat mewujudkan lingkungan rumah yang aman bagi anak.
Phytochemical and Antioxidant Capacity Test on Turmeric Extract (Curcuma Longa) Traditionally Processed in Bali Permatananda, Pande Ayu Naya Kasih; Aryastuti, Anak Agung Sri Agung; Cahyawati, Putu Nita; Udiyani, Desak Putu Citra; Wijaya, D.; Pandit, I Gde Suranaya; Wirajaya, Anak Agung Ngurah Mayun
Bali Membangun Bali: Jurnal Bappeda Litbang Vol 1 No 2 (2020): August 2020
Publisher : Badan Riset dan Inovasi Daerah Provinsi Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51172/jbmb.v1i2.115

Abstract

Purpose: The purpose of this study was to determine the ways and objectives of the use of turmeric by Balinese, as well as the phytochemical content and antioxidant capacity of turmeric extract which is traditionally processed in Bali. Research methods: The method and purpose of utilizing turmeric were obtained through observation and interviews with 900 Balinese respondents. Quantitative phytochemical tests include starch, protein, flavonoid, tannin, phenol and vitamin C levels and qualitatively for the presence of triterpenes, steroids, alkaloids, and saponins. Antioxidant capacity was measured using the DPPH method. Findings: Through this research, we found there were only 36.8% of respondents had ever used turmeric as a traditional medicine. Utilization of turmeric was mostly in the form of loloh or traditional drinks. Phytochemical test results showed turmeric extract had 67.38% starch, 3.42% protein, 2709.39 mg/100 gr flavonoids, tannins 291.64 mg/100gr, phenol 1584.04 mg/100 gr, and vitamin C 0.06 mg/100gr. Qualitatively, turmeric extract contained triterpenes, alkaloids, and saponins, but did not contain steroids. The antioxidant capacity of turmeric extract was 70.9 mg/L GAEAC. Implications: Turmeric extract is a traditional medicine made from nature that is most commonly used by Balinese and very potential to be developed as an antibacterial, antioxidant, anti-inflammatory, or other benefits that still need further investigation.
Chemical and Microbiological Characteristics of Sei-Pindang Tuna Fish I Gde Suranaya Pandit; Pande Ayu Naya Kasih Permatananda; I Nengah Suaria
Formosa Journal of Multidisciplinary Research Vol. 2 No. 12 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjmr.v2i12.7258

Abstract

Pindang is a fishery processing product that plays an important role in post-harvest activities. Pindang products have a relatively short shelf life, namely less than 2 days at room temperature. Smoking is a drying technique used to maintain the shelf life of fish by using wood fuel as a smoke producer. Pindang tuna that has undergone the smoking process is given the name Sei-Pindang Ikan Tongkol. The aim of this research is to determine the chemical and microbiological characteristics of Sei-Pindang Tuna Fish. The results showed that sei-pindang tuna had a water content of 44.69 ± 0.66%, histamine content of 11.88 ± 1.12 mg N/100 g, total volatile bases content of 43.23 ± 0.22 mg N/100 g and the total number of bacteria was 2.1 x104 ± 1.2 x103 cfu/g.
LAW ENFORCEMENT OF ILLEGAL BUSINESS TRANSACTION ON THE BORDER AREA BETWEEN INDONESIA AND TIMOR LESTE IN A DILEMMA Mahendrawati, NLM; Pandit, I Gde Suranaya; Sujana, IN; Nahak, S; Soares, C.A.; Telman, A. M.
Jurnal Hukum dan Peradilan Vol 10 No 1 (2021)
Publisher : Pusat Strategi Kebijakan Hukum dan Peradilan Mahkamah Agung RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25216/jhp.10.1.2021.115-138

Abstract

This study is a type of empirical legal study conducted based on the discrepancy between the existing provisions and theories and the legal facts occurring among the society, that is, the transaction of goods carried out by crossing the border between two countries.Any hindering obstacles and barricades to the law enforcement over illegal businesses can be settled through social and cultural, economic, political, and security approaches. Alternative solutions that should be applied in dealing with such legal issues can be establishing buildings in the border area, which are specifically directed to help accelerate the handling of three fundamental problems faced in the scope of the development of the border area in question, one of which is delimitation and delineation aspects of the state's boundaries, the aspect of affirming national borders on watershed areas between Indonesia and Timor Leste, the aspect of development discrepancy in the form of fulfilling infrastructure needs in the economic field to foster opportunities for the border areas to participate and compete amid both global and regional markets.
Ulasan: Beberapa Jamur Liar yang Berpotensi Menyebabkan Keracunan di Indonesia Permatananda, Pande Ayu Naya Kasih; Pandit, I Gede Suranaya; Putra, Ivan Permana
Al-Kauniyah: Jurnal Biologi Vol. 18 No. 1 (2025): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v1i1.34781

Abstract

AbstrakJamur merupakan fungi dengan bentuk makroskopik yang terdistribusi pada berbagai relung ekologi. Pemanfaatan jamur sebagai bahan pangan dan medis telah dilakukan sejak lama di seluruh dunia, termasuk Indonesia. Namun, karena secara morfologi tubuh buah jamur sering kali terlihat identik antara satu dengan lainnya, keracunan jamur menjadi resiko yang sering muncul. Hingga saat ini catatan keragaman, potensi pemanfaatan, dan informasi mengenai keracunan jamur liar di Indonesia masih sangat minim. Ulasan ini bertujuan untuk memberikan informasi beberapa jamur liar beracun (hasil penelitian penulis, diskusi dengan penggiat jamur, dan studi literatur) yang dilengkapi dengan deskripsi jamur sebagai media diseminasi ilmu mikologi. Sebanyak 11 kelompok jamur diuraikan pada tulisan ini yaitu Amanita spp., Chlorophyllum molybdites, Clarkeindat trachodes, Cantharocybe cf. virosa, dan Coprinus spp. Pada fase tua, Gymnopilus sp., Inocybe sp., Lepiota sp., Panaeolus sp., Podostroma cornu-damae, dan Scleroderma spp.Beberapa jamur tersebut telah dilaporkan menyebabkan keracunan hingga kematian di Indonesia. Sebagian besar kasus keracunan terjadi akibat kesalahan identifikasi beracun sebagai jamur edible. Namun, beberapa  genus jamur yang dilaporkan juga memiliki spesies yang bisa dikonsumsi pada jenis yang tepat atau umur tubuh buah. Identifikasi yang baik dan pengalaman saat merambah jamur liar merupakan salah satu cara untuk membedakan jamur liar beracun dan konsumsi.AbstractMushrooms are macroscopic forms of fungi that are distributed in various ecological niches. The utilization of mushrooms as food and medical ingredients has been done for a long time all over the world, including Indonesia. However, because morphologically the fruiting bodies of mushrooms often look identical to each other, mushroom poisoning is a risk that often arises. Until now, records of diversity, potential utilization, and information on wild mushroom poisoning in Indonesia are still minimal. This review aims to provide information on several poisonous wild mushrooms (the results of the author's research, discussions with mushroom activists, and literature studies) equipped with mushroom descriptions as a medium for disseminating mycological science. A total of 11 groups of fungi are described in this paper, namely Amanita spp., Chlorophyllum molybdites, Clarkeindat trachodes, Cantharocybe cf. virosa, and Coprinus spp. in the old phase, Gymnopilus sp., Inocybe sp., Lepiota sp., Panaeolus sp., Podostroma cornu-damae, and Scleroderma spp. Some of these fungi have been reported to cause poisoning and death in Indonesia. Most of the poisoning cases occurred due to misidentification of the poisonous mushrooms as edible mushrooms. However, some of the reported fungal genus mushrooms also have species that can be consumed at the right type or age of the fruiting body. Good identification and experience when foraging for wild mushrooms is one way to differentiate between poisonous and edible wild mushrooms.
Quality Evaluation of Frigate Mackarel Fish Pindang and Flying Fish Pindang from Fish Processing Centers in Kusamba Village, Klungkung Regency, Bali Pandit, I Gde Suranaya
AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment) Vol. 7 No. 2 (2023)
Publisher : Asia Pacific Network for Sustainable Agriculture, Food and Energy (SAFE-Network)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29165/ajarcde.v7i2.274

Abstract

Pindang is one of the traditional processed products derived from fish. Various types of fish can be processed into pindang, namely frigate mackerel fish, flying fish, sardinella, tuna, mackarel, cakalang and milkfish. Various types of fish cause various types of processing are carried out by the community and will eventually produce different quality. The purpose of this study was to evaluate and analyze the chemical, microbiological and organoleptic quality produced. Quality evaluation in comparative experimental research by comparing the quality of frigate mackarel fish pindang with flying fish. Parameters evaluated included chemical parameters, namely water content, salt content, histamine content, total volatile bases content, and trimethylamine content, microbiological parameters such as the number of bacteria, as well as organoleptic parameters including appearance, smell, texture, and taste. Based on the results of the study, the quality of frigate mackerel pindang with flying fish had significantly different qualities, especially in chemical assessment and organoleptic assessment.