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All Journal Jurnal Gamma Journal of Agroecology Prosiding Seminar Biologi Journal of Telematics and Informatics Jurnal Penelitian Tanaman Industri Jurnal Sain Peternakan Indonesia Folia Medica Indonesiana Jurnal Kebidanan Proceeding of the Electrical Engineering Computer Science and Informatics Kultivasi Jurnal Kebidanan Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Inovasi J-Dinamika: Jurnal Pengabdian Kepada Masyarakat JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Jurnal Penelitian Tanaman Industri (Littri) Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Ide Bahasa Jurnal Kebidanan Indonesia CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Jurnal Ilmu Keperawatan dan Kebidanan Jurnal Pengabdian Masyarakat Sasambo Midwifery Care Journal Window of Midwifery Journal Jurnal Abdi Masyarakat Multidisiplin Journal of Tropical Crop Science and Technology Jurnal Bidan Mandira Cendikia
Maftuchah Maftuchah
Universitas Muhammadiyah Malang
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Journal : JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga

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Arterial Blood Gas Parameters to Evaluate Oxygenation and Acid-Base Disorders in Corticosteroid-Receiving Severe and Critical COVID-19 Patients Temenggung, Bintang; Setiawan, Herley Windo; Rochmanti, Maftuchah; Rosyid, Alfian Nur
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 15 No. 2 (2024): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V15I22024.64-69

Abstract

Highlights: Both severe and critical COVID-19 patients primarily presented with hypoxemia. Severe and critical COVID-19 patients differed through their tendencies towards respiratory alkalosis/metabolic acidosis and respiratory acidosis, respectively.   Abstract Introduction: Increased inflammation and immune dysregulation in severe and critical COVID-19 trigger oxygen and acid-base disorders, possibly mitigated by corticosteroids. Variations in arterial blood gas (ABG) parameters and the influence of corticosteroid administration have become a concern for clinicians. This study aimed to uncover significant differences in temporal arterial blood gas parameters between severe and critical COVID-19 cases undergoing corticosteroid treatment. Methods: This case-control study, which adhered to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines, analyzed severe (n=27) and critical (n=41) COVID-19 patients treated in the high care unit (HCU) and the intensive care unit (ICU) of Universitas Airlangga Hospital, Surabaya, from May to July 2021. Arterial blood gas results were categorized into three evaluations (E1-E3) based on collection days. The International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) for Macintosh version 27.0 was used for statistical analysis, with a p<0.05 considered statistically significant. Results: Hypoxemia through PaO2 and P/F ratios was prominent in both groups throughout E1-E3, with differences only in E1 P/F ratios (p=0.003). While SaO2 stayed normal in severe cases, critical cases were low, with differences in E1 (p=0.012) and E3 (p=0.004). Severe cases maintained normal pH, while critical cases tended towards acidemia, notably differing in E1-E3. Both groups had low HCO3 levels, differing only in E2 (p<0.001). Severe and critical groups exhibited low and high PaCO2 trends, respectively, with distinctions in E2 (p<0.001) and E3 (p=0.003). Conclusion: Hypoxemia was prevalent in both groups. Compensated respiratory alkalosis or metabolic acidosis was common in the severe group, while the critical presented with respiratory acidosis.
Co-Authors Abbabiel, Yudantara Ekanaradhipa Abdul Gofur Abdul Khairul Rizki Purba Mustofa Indwiani Astuti ABDUL ROHMAN Achlaq, Mochammad Mizanul Achmad Basori, Achmad Adri Gabriel Sooai Aghnaita, Safira Agus Zainudin Agus zainudinn Ahmad Darda Akbar Kurniawan, Mohammad Al-Azam, Moh Noor Ali Ikhwan Amalu, Citra Anindito, Benediktus Annette d’Arqom, Annette Ardiany, Deasy Arifa Mustika Aris Winaya Arista Wahyu Ningsih Aulia Zakia Aulia Zakia Awalia BAMBANG HELIYANTO Benediktus Anindito Budiman Abdullah Chatarina Umbul Wahyuni Dewi Mayangsari Dewi Ratna Sari Dewi, Mariza Mustika Dharmawan, Mochamad Rangga Alif Dian Puji Rahayu Dini Kurniawati Erfan Dani Erfan Dani Septia Fatimah, Nurmawati Fauzan, Fauzan Fauziah Winda Gurnita HADI SUDARMO Hadi Sudarmo Handayani, Anggun Fitri Haq, Farhan Chairul Hari Basuki Notobroto Helvi Ardana Reswari Hendry Sulistiyanto Herley Windo Setiawan Hermeksi Rahayu Hilman, Evert Haryanto I Ketut Suada Iis Siti Aisyah Ilmiyah, Isnanda Rosyidatul Indah Wulaningsih Indiastuti, Danti Nur Kuntaman Kuntaman Lim, Anthony Camilo Maria Suryaningsih Mar’ah, Zakiyyatun Mochamad Mizanul Achlaq Mochammad Mizanul Achlaq Moh Noor Al-Azam Moh Noor Al-Azam Munafiah, Durrotun Novia Eka Cahyani Novita Sari Nurfutika, Mifta Nurina Hasanatuludhhiyah Permana, Putu Bagus Dharma Poppy Rahmatika Primandiri Prastyani, Reni Putri Rahma Dini Rahadianto, Prabowo Rimbun, Rimbun Rosantia Sarassari Rose Nur Hudhariani Rose Nurhudhariani, Rose Rosyid, Alfian Nur Royhanaty, Isy RULLY DYAH PURWATI Solly Aryza Sony Wibisono Sri Purwaningsih Suhud, Hargokendar Sulistyawati Sulistyawati Susi Susilawati Syawal, Syawaliyah Putri Andini Temenggung, Bintang Ulfah, Rizqa ulya, Fitria hikmatul Wahyunik, Siti Ida Widyanrika, Farahdiva Audrey Witri Hastuti Wungu, Citrawati Dyah Kencono Yasmeen Lashari Yoga Andi Kurniawan Yuani Setiawati Zainudinn, Agus