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All Journal Jurnal Kimia (Journal of Chemistry) Jurnal Ilmu Dasar Cropsaver : Journal of Plant Protection STOMATOGNATIC- Jurnal Kedokteran Gigi Chimica et Natura Acta Indonesian Journal of Chemistry Chemistry Indonesian Journal of Chemical Research Molekul: Jurnal Ilmiah Kimia Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Makara Journal of Science YASIN: Jurnal Pendidikan dan Sosial Budaya ANWARUL: Jurnal Pendidikan dan Dakwah Bandung Conference Series: Pharmacy Molekul: Jurnal Ilmiah Kimia Semeton Mathematics Journal Hikmah: Jurnal Studi Pendidikan Agama Islam Candradimuka: Journal of Education
Rani Maharani
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Education Engineering Environmental Science Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Chemistry Indonesian Journal of Chemical Research

 1 
Sintesis Tetrapeptida Linear (DPAP) Menggunakan Metode Sintesis Peptida Fasa Padat (SPPS) Dan Aktivitas Insektisidanya Terhadap Ulat Krop Kubis Yanti, Eka Fitri; Maharani, Rani
Indonesian Journal of Chemical Research Vol 8 No 1 (2020): Edisi Bulan Mei (Edition for May)
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2020.8-eka

Abstract

Crop cabbage worm (Crocidolomia pavonana) is one of the pests that has a bad effect on the cabbage production in Indonesia. One of the efforts that has been applied to control this pest is by using bayrusil. However, the bayrusil can cause negative effects such as poisoning and environmentally polluting effects. To prevent the undesired effects, it has been developed the use of environmentally friendly insecticide and one of them is the use of insecticidal peptide. Tripsin-modulating oostatic factor (TMOF) and ist analogues is one of the peptides that has an insecticidal activity. The aim of this research is to synthesise a linear tetrapeptide (DPAP) an analogues of TMOF and to test insecticidal activities against crop cabbage worm. A DPAP has been synthesised by Solid Phase Peptide Synthesis on 2-chlorotrytil chloride resin. Fmoc strategy was applied on the synthesis and a combination DIC/Oxime was employed in the coupling reaction.The tetrapeptidyl resin was cleaved by TFA:water:EDT (90:5:5). The peptide was purified by reverse-phase column chromatography and characterized by TOF ES-MS spectroscopy. A linear peptide was biologically tested towards the C. pavonana, showing percentage of mortality values at 1000 ppm.
Co-Authors 10060321019, Dinah Shafira Abasi Ace Tatang Hidayat Achmad Zainuddin Adhitthana Wiguna Ari Tri Wanodyo Handayani Ariq, Muhammad Ayu Andini Azmi, Mohamad Nurul Dadan Sumiarsa Danar Dono Darwati Darwati Darwati, Darwati Deden Indra Dinata, Deden Indra Desi Harnet Desi Harneti Putri Huspa Dina Puspitasari DUDI RUNADI Dwi Maulidani Fadhlan Eka Fitri Yanti, Eka Fitri Euis Julaeha Fadillah, Yusuf Fahmi Faturahman Fajar Fauzi Abdullah Fajar Fauzi Abdullah Farabi, Kindi Ferry Ferdiansyah Sofian, Ferry Ferdiansyah Gunawan, Latifah Hedi Paramita Hidayatunnisa, Nurul Hilmayanti, Erina Ika Wiani Jamaludin Al-Anshori Khalijah Awang Kindi Farabi Kindi Farabi Kindi Farabi Kiswaluyo . Kusumawardhani, Ayuning Dyah Lindung Tri Puspasari Lindung Tri Puspasari Magdalena, Ina Muchlis, Handi Nugraha Muhamad Naufal Muhammad Hanafi Muhammad Naufal, Muhammad Muhammad Rijal Alfian Mustaqim, Iqbal Wahyu Mustofa, Hidayat Nurul Muttaqin, Fauzan Zein N, Gilang Kusuma Nadya Thufaila Nafiah, Mohamad Azlan Naini, Al Arofatus Nety Kurniaty Nurlelasari Nurlelasari Paramita, Hedi Puji Rahayu Purnama Purnama Revan Hardiawan Rika Meliansyah RIKA MELIANSYAH Rismawati Rismawati Robbaniyyah, Nuzla Af'idatur Ropidoh, Siti Safri Ishmayana Safri Ishmayana Selly Marita Serlin Sepriyanti Dohare Shiono, Yoshihito Siska Elisahbet Sinaga Sofa Fajriah Sofa Fajriah Taufiqqurahman, Taufiqqurahman Tharysa Rizqika Putri Tiara Prima Amalya Tri Mayanti Ulfa, Kurnia Unang Supratman Urfa, Salsa Rojana Wawan Hermawan Yoshihito Shiono Yoshihito Shiono Yusuf Hidayat Yusuf Hidayat Yusup Hidayat