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Sintesis Senyawa 5-(4-klorobenzilidena)imidazolina-2,4-dion Naufal, Muhammad; Maharani, Rani; Wiani, Ika
Chimica et Natura Acta Vol 5, No 1 (2017)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (619.085 KB) | DOI: 10.24198/cna.v5.n1.12820

Abstract

Senyawa benzalhidantoin atau 5-benzilidena-imidazolidina-2,4-dion (3) merupakan senyawa yang dapat diisolasi dari spons merah laut Laxosubrites sp. dan memiliki aktivitas antikejang serta antikanker prostat PC-3M. Senyawa tersebut sudah disintesis sejak beberapa dekade yang lalu dan banyak diteliti bioaktivitasnya, baik di bidang kesehatan maupun pertanian. Penelitian di bidang kesehatan, contohnya sebagai agen antikonvulsan, antivirus, inhibitor EGFR dan antiproliferasi sel A431, antikanker sel HepG2, antimetastatik sel kanker PC-3M, inhibitor enzim tirosinase dan pembentukan melanin serta di bidang pertanian sebagai herbisida dan fungisida. Tujuan dari penelitian ini adalah mensintesis senyawa 5-(4-klorobenzilidena)-imidazolidina-2,4-dion (7) melalui reaksi kondensasi antara hidantoin (1) dengan 4-klorobenzaldehida (2) menggunakan pereaksi natrium bikarbonat dalam etanol, dan etanolamina sebagai katalis basa (metode Eli Lily). Hidantoin (1) dan 4-klorobenzaldehida (2) sebagai senyawa prekursor diperoleh secara komersil. Sintesis dilakukan dengan cara mereaksikan senyawa hidantoin (1) dan 4-klorobenzaldehida (2) secara stokiometri dengan katalis basa etanolamina dalam etanol dan air (modifikasi metode Eli Lily) dan direfluks selama 6 jam. Senyawa hasil sintesis dimurnikan dengan cara rekristalisasi dari etanol panas, diperoleh kristal putih berbentuk jarum 5-(4-klorobenzilidena)-imidazolidina-2,4-dion (7) dengan rendemen 12%. Senyawa tersebut dianalisis dengan menggunakan KLT silika gel GF254, aseton-heksana (1:1 v/v) memberikan harga Rf = 0,625 untuk senyawa (7) dengan titik leleh (TL)=292-294°C (TL lit.=294-296°C). Selanjutnya, senyawa tersebut diidentifikasi strukturnya menggunakan spektroskopi UV, IR, HR-TOF-MS ES+, 1H-NMR dan 13C-NMR, yang menunjukkan konsistensi senyawa hasil sintesis dengan senyawa 5-(4-klorobenzilidena)-imidazolidina-2,4-dion (7).
Dampak Siklon Tropis Savannah pada Karst Window Kalinongko, Karst Gunungsewu, Kabupaten Gunungkidul, Indonesia Riyanto, Indra Agus; Cahyadi, Ahmad; Ramadhan, Fajri; Naufal, Muhammad; Widyastuti, Margaretha; Adji, Tjahyo Nugroho
Jurnal Geografi : Media Informasi Pengembangan dan Profesi Kegeografian Vol 17, No 1 (2020): January
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jg.v17i1.21419

Abstract

Siklon Tropis Savannah melewati Daerah Istimewa Yogyakarta pada tanggal 17 Maret 2019. Curah hujan yang disebabkan oleh Siklon Tropis Savannah terekam pada stasiun Geofisika badan meteorologi, klimatologi dan Geofisika (BMKG) Yogyakarta sebesar 170,6 mm/hari dan terekam pada Stasiun Cuaca Beton milik Kelompok Studi Karst Fakultas Geografi Universitas Gadjah Mada sebesar 78,3 mm/hari. Curah hujan menunjukkan bahwa siklon tropis ini menyebabkan terjadinya hujan ekstrim. Siklon Tropis Savannah menyebabkan bencana banjir di beberapa wilayah Daerah Istimewa Yogyakarta salah satunya terjadi di Karst Window Kalinongko, Kawasan Karst Gunungsewu, Kabupaten Gunungkidul. Karst Window Kalinongko terdampak banjir dari meluapnya sungai bawah tanah. Proses terjadinya banjir di Karst Window Kalinongko disebabkan oleh aliran air yang melebihi kapasitas pengaliran dari lorong konduit pada sungai bawah tanah. Sistem konduit yang penuh kemudian meluap ke permukaan dan menggenang pada bagian dolin di sekitar Karst Window Kalinongko. Waktu surut banjir airtanah di Karst Window Kalinongko adalah selama 10 hari. Banjir Siklon Tropis Savannah yang menggenang memiliki volume sebesar 4.894.258 m3, luasan area terdampak seluas 13.723 m2, dan ketinggian genangan 6 meter. Dampak genangan banjir airtanah yang disebabkan Siklon Tropis Savannah di Karst Window Kalinongko merendam lahan sawah seluas 10.586 m2 dan perkebunan seluas 3.137 m2.
Hydrogeology of Mangsri Cave, Gunungsewu Karst Area, Java Island, Indonesia Cahyadi, Ahmad; Reinhart, Hilary; Wahyu Ristiawan, Angga; Dwi Putra, Rakhmat; Labib, M. Ainul; Naufal, Muhammad; Agus Riyanto, Indra; Ramadhan, Fajri; Dwi Laksono, Angga
Sumatra Journal of Disaster, Geography and Geography Education Vol 5 No 1 (2021): Sumatra Journal of Disaster, Geography and Geography Education (June Edition)
Publisher : Sumatra Journal of Disaster, Geography and Geography Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.522 KB) | DOI: 10.24036/sjdgge.v5i1.356

Abstract

The Gunungsewu karst area is not only known for its unique landscape but also its recurring drought events. To meet the water supply, the local population utilizes several water potentials, namely doline pond, spring, and underground river. This study was designed to analyze the hydrogeological conditions of Mbangsri Cave, following its accidental discovery by the community at the end of 2018. The hydrogeological analysis was conducted by geological surveys, which consisted of rocks collection and structural measurements, cave mapping, and recharge area delineation based on remote sensing images acquired by unmanned aerial vehicles. The results showed that Mbangsri Cave, in the hydrogeological perspective, had low water resources potential. It is believed to be the result of (1) relatively small catchment area, (2) a fault in the southern part of Mbangsri Cave, creating a small groundwater basin, and (3) the thin epikarst layer, limiting the water storage.
Dampak Siklon Tropis Savannah Terhadap Karakteristik Hidrogeokimia Aliran pada Mata Air Guntur, Kawasan Karst Gunungsewu Ramadhan, Fajri; Riyanto, Indra Agus; Cahyadi, Ahmad; Naufal, Muhammad; Widyastuti, M; Adji, Tjahyo Nugroho
Jurnal Geografi : Media Informasi Pengembangan dan Profesi Kegeografian Vol 18, No 2 (2021): In progress [July 2021]
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jg.v18i2.30293

Abstract

Tropical Cyclones often occur in Indonesia and have disastrous impacts. Until now, no research has focused on time series data related to groundwater discharge and chemistry due to tropical cyclones. Therefore, this study aims to analyze and compare the characteristics of the hourly time series, both discharge and chemistry of the Guntur karst springs. Guntur Spring was affected by the tropical cyclone of Savannah on March 17, 2019. The method used in this study consisted of two parts, namely the analysis of the discharge and chemistry of Guntur Spring. Discharge analysis was performed by correlation test with rain intensity. Chemical analysis was carried out using the Minister of Health Regulation No. 90 of 2002 and expert standards. Other chemical analyzes were performed using a triangular piper, rectangular piper, and stiff diagram of the parameters Na+, K+, Ca2+, Mg2+, SO42-, Cl-, and HCO3-. The results of the relationship between discharge and rain intensity are directly proportional and increase significantly during a cyclone. The results of analysis of the Guntur Springs during Tropical Cyclone Savannah, all parameters are in accordance with the quality standard. In addition, there was a reduction in ion content due to the dilution process of Ca2+, Mg2+, Cl-, HCO3-., DHL, and pH ions compared to non-cyclone, Beton Resurgence, and Gremeng Resurgence ions. The chemical results when the cyclone is different compared to non-cyclone, Gremeng Resurgence and Beton Resurgence with a characteristic decrease in ionic content.
PENERAPAN TEKNIK ADAPTIVE DAN HISTOGRAM EQUALIZATION DALAM PENGOLAHAN CITRA Naufal, Muhammad; Al Azies, Harun; Firmansyah, Gustian Angga; Kharisma, Ni Made Kirei
Jurnal Mahasiswa Ilmu Komputer Vol. 5 No. 1 (2024): Jurnal Mahasiswa Ilmu Komputer March 2024
Publisher : Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/ilmukomputer.v5i1.5345

Abstract

Mengantuk saat berkendara menjadi ancaman serius yang dapat meningkatkan risiko kecelakaan, yang merupakan penyebab utama kematian di seluruh dunia, termasuk di Indonesia. Deteksi dan pencegahan kondisi mengantuk pada tahap awal menjadi krusial untuk mengurangi potensi kecelakaan dan meningkatkan keselamatan berkendara. Penelitian ini fokus pada pemanfaatan citra wajah pengemudi sebagai metode efektif dalam mendeteksi mengantuk. Rendahnya kontras dalam citra dapat mempengaruhi deteksi wajah, sehingga diperlukan peningkatan kontras citra. Dalam penelitian ini, dua teknik peningkatan kontras citra, yaitu Histogram Equalization (HE) dan Adaptive Histogram Equalization (AHE), dievaluasi. Dataset yang digunakan adalah Driver Drowsiness Dataset, terdiri dari citra Drowsy sebanyak 22,348 dan Non-Drowsy sebanyak 19,445. Pra-pemrosesan melibatkan resize dan pengaburan menggunakan Gaussian Blur, diikuti oleh penerapan HE dan AHE. Evaluasi kinerja dilakukan menggunakan matriks evaluasi, menghasilkan skor Mean Squared Error, Peak Signal-to-Noise Ratio, dan Signal-to-Noise Ratio. Hasil menunjukkan bahwa HE memberikan hasil yang lebih baik dengan skor MSE 101.21, PSNR 28.11, dan SNR 0.19, dibandingkan dengan AHE yang memiliki skor MSE 103.92, PSNR 27.97, dan SNR 0.04. Oleh karena itu, dapat disimpulkan bahwa HE memberikan peningkatan kontras yang lebih baik untuk citra wajah dibandingkan dengan AHE.
PEMBANGUNAN PERANGKAT LUNAK KOMUNITAS MEDIA MUSIK DENGAN FRAMEWORK REACT NATIVE DAN FIREBASE BERBASIS ANDROID DAN IOS Wibawa, Yohanes Eka; Naufal, Muhammad
Jurnal SISKOM-KB (Sistem Komputer dan Kecerdasan Buatan) Vol. 6 No. 2 (2023): Volume VI - Nomor 2 - Maret 2023
Publisher : Teknik Informatika, Sistem Informasi dan Teknik Elektro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47970/siskom-kb.v6i2.515

Abstract

Abstract—Pembangunan aplikasi ini berupa aplikasi Mobile Android dan IOS, dimana kedua platform OS (Operating System) itu sudah menguasai pangsa pasar, dengan pengguna terbanyak di seluruh Indonesia. Aplikasi ini dibuatkan khusus untuk PT Boleh Net Indonesia (Boleh Music). Dalam pembuatan aplikasi ini dibangun dengan menggunakan EXPO. EXPO adalah framework React Native yang didalamnya terdapat SDK (Software Devolopment Kit) yang memungkinkan untuk membangun aplikasi Android dan IOS secara bersamaan. Sedangkan React Native sendiri adalah framework javascript yang dibangun oleh Facebook. Dan metode yang digunakan dalam pembangunan perangkat lunak ini adalah Scrum salah satu metode perancangan Agile.
Deep learning for audio signal-based tempo classification scenarios Muljono, Muljono; Nurtantio Andono, Pulung; Ayu Wulandari, Sari; Al Azies, Harun; Naufal, Muhammad
IAES International Journal of Artificial Intelligence (IJ-AI) Vol 13, No 2: June 2024
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijai.v13.i2.pp1687-1701

Abstract

This article explains how to determine the tempo of the kendhang, an Indonesian traditional melodic instrument. This research presents novelty as technological research related to gamelan instruments, which has rarely been achieved thus far, through the introduction of kendhang tempo types through the sounds produced, with the hope of creating an automatic system that can recognize the kendhang tempo during a gamelan performance. The testing in this work will categorize the tempo of kendhang into three categories: slow, medium, and fast, utilizing one of the two scenario models proposed, mel frequency cepstral coefficients (MFCC) and convolutional neural network (CNN) in the first scenario, and mel spectrogram and CNN in the second. Kendhang's original audio data, which was captured in real time and later enhanced, makes up the data set. The model 1 scenario, which entails feature extraction using MFCC and classification using the CNN classification approach, is the best scenario in this research, based on the experimental results. When compared to the other suggested modeling scenarios, model 1 has a level of 97%, an average accuracy, and a gain value of 96.67%, making it a solid assistant in terms of kendhang's good tempo recognition accuracy.
PELATIHAN DAN PENDAMPINGAN PETANI DALAM PENGGUNAAN PGPR UNTUK BUDIDAYA TANAMAN HORTIKULTURA DI DESA BINTURU KECAMATAN KELUA KABUPATEN TABALONG, KALIMANTAN SELATAN Sepe, Muslimin; Rosa, Helda Orbani; Marsuni, Yusriadi; Hariyadi, Nursyifa Nada; Naufal, Muhammad
BAKIRA: Jurnal Pengabdian Kepada Masyarakat Vol 5 No 1 (2024): BAKIRA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/bakira.2024.5.1.32-39

Abstract

Plant Growth Promoting Rhizobacteria, or PGPRs, are a type of bacteria that live in rhizospheres, or the areas of land near tomato plants. These bacteria can cause a variety of processes, such as the formation of nitrogen, the breakdown of fat, the synthesis of phytohormones, and the development of illnesses. The purpose of this nirlaba service is to provide information and resources that are required for pet owners and pertanian owners in order to produce and use PGPR locally and effectively. This is expected to improve tuna quality, increase tuna health, and result in more efficient use of pupuk. The training's outcome indicates that participants can create and use PGPR on their own effectively, increasing textile production on a global scale. This training also emphasizes the importance of environmental sustainability and resiliency through the use of PGPR agents.
Analisis Penyelesaian Aksi Mogok Kerja Karyawan PT. Swakarya Indah Di Kota Tanjungpinang Tahun 2023 Wulansari, Rindi; Habibi, Alif Farhan; Naufal, Muhammad; Candra, Mellyana
Jurnal Ilmu Komunikasi Dan Sosial Politik Vol. 1 No. 2 (2023): September - Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstracts are written in English and Indonesian (except articles written in English) which contain the main issues, research Disputes that occur in the world of work are not difficult to encounter. Disputes that occur can also involve various kinds of problems between workers or labor unions and the company. Problems in industrial relations must find a way out so that they can be resolved. This research aims to analyze the resolution of the strike action carried out by PT employees. Beautiful DIY Clothing. The method used in this research study is literature study. The data source obtained in this research was by reading and studying what happened in the field based on facts. The results of this research were strike actions carried out by employees of PT. Swakarya Indah Busana is a salary arrears that have not been paid by the company for three months. Bipartite settlement efforts between union representatives and company leadership.
Assessing karst landscape degradation based on the void development of karst aquifers in Gunungsewu, Indonesia Naufal, Muhammad; Adji, Tjahyo Nugroho; Haryono, Eko; Cahyadi, Ahmad
Journal of Degraded and Mining Lands Management Vol. 11 No. 3 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15243/jdmlm.2024.113.5707

Abstract

Compared to other landforms, karst areas are among those emerging from the dissolution process that have a higher risk of land degradation. The likelihood of karst landforms being harmed is increased by urbanization and other human activities like extensive agriculture. Subsurface streams' water quality gets worse when surface pollutants infiltrate through developed karst features like sinkholes and karst ponors. There is a greater risk of land degradation as more karst features, in this case void size, develop. The purpose of this research is to assess how void development, or the degree of karstification, relates to the potential for karst spring pollution in the event that land degradation occurs on the surface of the Karst Drainage System (KDS). This research was conducted at the KDS of Beton and Gremeng Spring in the Gunungsewu karst area, Indonesia. In addition, this study also provides recommendations related to environmental management on the basis of the level of development of voids at both sites. The degree of karstification represents the phase at which a hydrogeological system has been developing, and this information was later considered in formulating strategies for protecting karst groundwater from contamination. The results show that Beton and Gremeng had a complex discharge regime with degrees of karstification at 8 and 5.5, respectively. Based on flood hydrograph components, it was further confirmed that both areas were in the mature phase. The higher the degree of karstification, the higher the vulnerability to pollution.
Co-Authors Achmad Achmad Ade Gohan, Muhammad Agmi, Nadia Agus Riyanto, Indra Ahmad Cahyadi **) Ahmad Suriansyah Ahsyar, Tengku Khairil Akrom, Muhamad Al-Azies, Harun Alfitri, Mira Alzami, Farrikh Amanda Cahyadewi, Felicia Andayan, Melia Andrean, Muhammad Niko Anggi Pramunendar, Ricardus Anggita, Ivan Maulana Aprillia Dwi Ardianti Ayu Pertiwi Azka, Muhammad Azwar, Erizaldy Brawijaya, Kriska Budoyo, Joto Candra, Mellyana Chandra Pratama, Ragil Cinantya, Celia Darmawahyuni, Annisa Denta Saputra, Fahrizal Dinda Lestarini Dwi Laksono, Angga Dwi Putra, Rakhmat Eka Yuniarto Eko Haryono Endang Komariah, Endang Erwin Yudi Hidayat Fadillah Putra Fahmi Amiq Fauziah, Ismahani Febriyanto, Hendra Firdaus Firdaus Firmansyah, Gustian Angga Guruh Fajar Shidik Habibi, Alif Farhan Handayani, Ni Made Kirei Kharisma Hariyadi, Nursyifa Nada Hartono, Andhika Rhaifahrizal Harun Al Azies Hayatul Cholsy Helda Orbani Rosa Hermansyah Hidayat, Novianto Nur Hilary Reinhart Husaini Husda IDA RAHMAWATI Ika Wiani Inggih Permana Irawan, Diki Surya ISWAHYUDI ISWAHYUDI Jazman, Muhammad Jun Justinar K, M. Rizal Kharisma, Ni Made Kirei Khoirunnisa, Emila Kurniawan, Anggy Tyas Labib, M. Ainul Ledy Diana Listya Endang Artiani, Listya Endang Liya Umaroh, Liya Lusi Ariyani M Widyastuti Mallorca, Muhammad Nur Alfat Margaretha Widyastuti Marsuni, Yusriadi Marwan, Arif Masliana Masliana, Masliana Megantara, Rama Aria Moch Anjas Aprihartha Muhammad Aziz Muhammad Fachrurrozi Bafadal Muljono Muljono Muslem, Asnawi Mylova, Rezha Willy Putra Ningrum, Novita Kurnia Noor Ageng Setiyanto, Noor Ageng Norma Eralita Nurhayati Nurhayati Nursantri Yanti Onggo, Nico Pamungkas, Bintang Putra Dwi Prabowo, Wahyu Aji Eko Prayoga, Yegi Pulung Nurtantio Andono Putra, Permana Langgeng Wicaksono Ellwid Putri Rachmadani, Nisa Rajudin, Rajudin Ramadhan Rakhmat Sani Ramadhan, Fajri Rani Maharani Ricardus Anggi Pramunendar Richo Kurniawan, Ibnu RISAL, SYAHLAN Riswandi, Muh Syahlan Riyanto, Indra Agus Safitri, Aprilyani Nur Safitriani, Indah Samangi, Arfina Sari Ayu Wulandari Sarifah Putri Raflesia, Sarifah Putri Sariman, Syahrul Sa’adah, Muna Sepe, Muslimin Silalahi, Purnama Ramadani Siti Anisah Siti Nurmaini Sri Winarno Sudarmin Sudibyo, Usman Sumartono Sutomo, Rudi Tjahyo Nugroho Adji Tomy Perdana Trisnapradika, Gustina Alfa Ulhaq, M. Jia Umar Fakhrizal, Irsyad Wahyu Ristiawan, Angga Wibawa, Yohanes Eka Wulandari, Wita Wulansari, Rindi Yudhistira, M Halley Zahro, Azzula Cerliana Zami, Farrikh Al Zayn, Afta Ramadhan Zulfikar Jayakusuma