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Journal : Dentin

ANTIBACTERIAL EFFECTIVENESS OF WATER HYACINTH (Eichhornia crassipes) LEAF EXTRACT ON THE GROWTH OF Porphyromonas gingivalis Laili Nurul Islami; Beta Widya Oktiani; Yusrinie Wasiaturrahmah
Dentin Vol 7, No 2 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v7i2.9716

Abstract

Background: The most common periodontal disease is periodontitis which is frequently found in the form of chronic periodontitis. Such disease is caused by the accumulation of the bacterium Porphyromonas gingivalis where supporting therapy such as chlorhexidine gluconate mouthwash 0.2% can be given. However, its use in the long term can have a negative effect on the oral cavity. There is a natural plant, namely water hyacinth (Eichhornia crassipes) which contains compounds that can be used as antibacterial, such as: tannins, phenols, flavonoids, alkaloids, saponins, terpenoids, and steroids. As a result of this, the water hyacinth plant can be used as an alternative herbal medicine. Purpose: To analyze the antibacterial effectiveness of water hyacinth leaf extract (Eichhornia crassipes) against the growth of Porphyromonas gingivalis bacteria. Methods: This study used True Experimental with posttest only with control group design. Antibacterial test was performed using liquid dilution method to determine MIC and solid dilution to determine MBC. Results: Based on the results and data analysis, it was found that the water hyacinth leaf extract had MIC at 1,56% and MBC at a concentration of 50%. Conclusion: Leaf extract of water hyacinth (Eichhornia crassipes) can inhibit and have antibacterial properties against the growth of Porphyromonas gingivalis bacteria. Keywords:      Chronic periodontitis, Leaf extract of Water Hyacinth, Porphyromonas gingivalis
UJI TOKSISITAS EKSTRAK DAUN GALAM (Melaleuca cajuputi subsp. Cumingiana Barlow) PADA BHK-21 SEL FIBROBLAS Brachmedio Barito Syech Erlangga; Sherli Diana; Debby Saputera; Didit Aspriyanto; Beta Widya Oktiani
Dentin Vol 7, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v7i3.10743

Abstract

Latar Belakang: Karies gigi merupakan penyakit rongga mulut yang salah satu faktor penyebabnya adalah bakteri. Salah satu bahan alam yang berpotensi sebagai antibiotik dan hidup di lingkungan lahan basah adalah tanaman galam (Melaleuca cajuputi subsp. Cumingiana Barlow). Fungsi uji toksisitas adalah untuk mengetahui efek toksik dan batas dosis aman suatu senyawa kimia dalam penelitian ini pengujian ekstrak daun galam. Tujuan: Menganalisis efek toksik setelah pemberian ekstrak daun galam (Melaleuca cajuputi subsp. Cumingiana Barlow) terhadap sel fibroblas BHK-21. Metode: Penelitian ini adalah penelitian eksperimental murni (true experimental) dengan rancangan posttest-only with control group design untuk menganalisis toksisitas ekstrak daun galam terhadap sel fibroblas Baby Hamster Kidney-21 (BHK-21) dengan metode Microculture Tetrazolium Technique (MTT) assay secara in vitro. Hasil: Hasil penelitian menunjukkan bahwa ekstrak daun galam tidak toksik karena viabilitas sel pada semua konsentrasi >100% dan nilai IC50 yang tidak mungkin tercapai. Hasil uji post hoc Games-Howell menyimpulkan bahwa konsentrasi 50%, 75%, dan 100% lebih efektif daripada konsentrasi 0,125%, 0,2%, 0,25%, dan 0,4%. Kesimpulan: Tidak ada efek toksik ekstrak daun galam dengan uji MTT terhadap sel fibroblas BHK-21.Kata kunci: ekstrak daun galam, sel fibroblas BHK-21, toksisitas
UJI TOKSISITAS EKSTRAK DAUN KARAMUNTING (Rhodomyrtus tomentosa (Aiton) Hassk.) TERHADAP HATI TIKUS WISTAR Eka Dwita Natasya Fitri Siregar; Beta Widya Oktiani; Fajar Kusuma Dwi Kurniawan; Didit Aspriyanto; Ika Kusuma Wardani
Dentin Vol 8, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v8i2.13117

Abstract

ABSTRACTBackground: Medicinal plants are types of plants that can ability to effectively treat illnesses. One such plant is caramunting leaves (Rhodomyrtus tomentosa (Aiton) Hassk). The substance in caramunting leaves includes an antibiotic that can counteract infections in the body. To determine the safe dosage of a drug, it is necessary to conduct toxicity tests in vivo on the liver of Wistar rats based on SGOT and SGPT levels. Objective: To analyze the toxic effects of administering caramunting leaf extract (Rhodomyrtus tomentosa (Aiton) Hassk.) in doses of 600 mg/kgBW, 1,200 mg/kgBW, and 2,400 mg/kgBW orally on rat liver based on SGOT and SPGT levels. Method: This study employed a true experimental posttest-only control group design to test the toxicity of caramunting leaf extract on SGOT and SGPT levels in the liver of Wistar rats given orally. Results: Following a 28-day experimental period on research animals, SGPT levels were observed to range from 34.9 to 218.1 U/L, while SGOT levels ranged from 56.1 to 201.9 U/L. These findings remain within the normal range, indicating that the extract does not have a toxic effect on SGPT and SGOT. Conclusion: Karamunting leaf extract at doses of 600 mg/kgBW, 1,200 mg/kgBW, and 2,400 mg/kgBW did not exhibit a toxic effect on SGPT and SGOT levels in Wistar rats.Keywords :     Karamunting, Toxicity, SGOT, SGPT, Antibiotic. ABSTRAK Latar Belakang: Tanaman obat adalah tanaman yang mempunyai khasiat menyembuhkan suatu penyakit. Tanaman yang memiliki potensi tersebut adalah daun karamunting (Rhodomyrtus tomentosa (Aiton) Hassk). Kandungan yang terdapat pada daun karamunting bersifat sebagai antibiotik yang mampu mengatasi infeksi dalam tubuh. Untuk mengetahui batas rasional suatu obat, maka diperlukan penelitian uji toksisitas secara in vivo pada hati tikus wistar berdasarkan kadar SGOT dan SGPT. Tujuan: menganalisis efek toksik pemberian ekstrak daun karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.) dosis 600 mg/kgBB, 1.200 mg/kgBB, dan 2.400 mg/kgBB per oral pada hati tikus berdasarkan kadar SGOT dan SPGT. Metode: Penelitian ini menggunakan design true eksperimental dengan desain posttest-only with control design untuk menguji toksisitas ekstrak daun karamunting terhadap kadar SGOT dan SGPT pada hati tikus wistar yang diberikan secara oral. Hasil: Setelah dilakukan percobaan pada hewan penelitian selama 28 hari didapatkan kadar SGPT 34,9-218,1 U/L dan kadar SGOT 56,1–201,9 U/L. Nilai tersebut menunjukkan hasil tidak melebihi rentang normal yang mengartikan bahan penelitian tidak memiliki efek toksik pada SGPT dan SGOT. Kesimpulan: Ekstrak daun karamunting dengan dosis 600 mg/kgBB, 1.200 mg/kgBB, dan 2.400 mg/kgBB tidak memiliki efek toksik pada kadar SGPT dan SGOT tikus Wistar.Tidak terdapat efek toksik dari pemberian ekstrak daun karamunting dosis 600 mg/kgBB, 1.200 mg/kgBB, dan 2.400 mg/kgBB secara per oral terhadap kadar SGOT dan SGPT tikus Wistar. Kata kunci :  Antibiotik, Karamunting, SGOT, SGPT, Toksisitas
PERBANDINGAN EFEKTIVITAS MEDIA POP-UP BOOK & VIDEO ANIMASI KARTUN TERHADAP PENGETAHUAN KESEHATAN GIGI DAN MULUT PADA ANAK SD (Tinjauan Siswa SDN Kuripan 2 Banjarmasin) Stevani Stevani; Raden Harry Dharmawan Setyawardhana; Beta Widya Oktiani; I Wayan Arya Krishnawan Firdaus
Dentin Vol 8, No 3 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v8i3.14229

Abstract

Background: Dental and oral health is part of overall body health. In Indonesia, dental and oral health problems are still relatively high and the proportion of correct dental and oral health knowledge among elementary school children is still low. Providing health education through pop up books and animated cartoon videos can be used as information media to increase knowledge of dental and oral health in elementary school children. Objective: This study aims to analyze dental and oral health knowledge in elementary school children through pop up book media and animated cartoon videos on dental and oral health knowledge in elementary school children at SDN-SN Kuripan 2 Banjarmasin, Banjar Regency. Methods: Using a true experimental design with a pretest-posttest with control design with a simple random sampling technique. The research was carried out at SDN-SN Kuripan 2 Banjarmasin, Banjar Regency with a sample of 76 respondents. Results: The results of the T-Test Normality test data analysis showed that there was no difference in dental and oral health knowledge among elementary school children and before and after counseling (pop up book: p=13.16; animated cartoon video: p=13.63), There was no difference in dental and oral health knowledge in elementary school children between pretest and posttest (pop up book: p= 13.16; animated cartoon video: p=13.63). The results of the Mann Whitney test data analysis were p=0.097, which means oh, it is accepted, indicating there is no difference in knowledge of dental and oral health among elementary school children. Conclusion:. The conclusion of this research is that health knowledge education through pop up books and animated cartoon videos is equally effective for dental and oral health knowledge in elementary school children.Keywords: Counseling, dental and oral health, Pop Up Book, animated cartoon video ABSTRAKLatar belakang: Kesehatan gigi dan mulut merupakan bagian dari kesehatan tubuh secara keseluruhan. Di Indonesia masalah kesehatan gigi dan mulut masih tergolong tinggi dan proporsi pengetahuan kesehatan gigi dan mulut pada anak sekolah dasar yang benar masih rendah. Pemberian penyuluhan kesehatan melalui pop up book dan video animasi kartun dapat dijadikan sebagai media informasi untuk meningkatkan pengetahuan Kesehatan gigi dan mulut pada anak sekolah dasar. Tujuan: Penelitian ini bertujuan untuk menganalisis pengetahuan kesehatan gigi dan mulut pada anak sekolah dasar melalui media pop up book dan video animasi kartun terhadap pengetahuan kesehatan gigi dan mulut pada anak sekolah dasar pada siswa SDN-SN Kuripan 2 Banjarmasin, Kabupaten Banjar. Metode: Menggunakan true eksperimental design dengan rancangan pretest-postest with control design dengan teknik pengambilan sampel simple random sampling. Penelitian dilaksanakan di SDN-SN Kuripan 2 Banjarmasin, Kabupaten Banjar dengan sampel berjumlah 76 responden. Hasil: Hasil analisis data uji Normalitas T-Test menunjukkan tidak ada perbedaan pengetahuan Kesehatan gigi dan mulut pada anak sekolah dasar dan sebelum dan setelah penyuluhan (pop up book: p=13,16; video animasi kartun: p=13,63), tidak ada perbedaan pengetahuan kesehatan gigi dan mulut pada anak sekolah dasar antara pretest dan posttest (pop up book: p= 13,16; video animasi kartun: p=13,63). Hasil analisis data uji Mann Whitney p=0,097 yang berarti oh diterima menunjukkan tidak ada perbedaan pengetahuan kesehatan gigi dan mulut pada anak sekolah dasar Kesimpulan:. Kesimpulan penelitian ini adalah penyuluhan pengetahuan kesehatan melalui pop up book dan video animasi kartun sama efektif untuk pengetahuan kesehatan gigi dan mulut pada anak sekolah dasar.
UJI TOKSISITAS EKSTRAK DAUN KARAMUNTING (Rhodomyrtus tomentosa (Aiton) Hassk.) TERHADAP GINJAL TIKUS WISTAR (Berdasarkan Ureum dan Kreatinin) M. Ridhotama Wibowo; Beta Widya Oktiani; Melisa Budipramana; Maharani Laillyza Apriasari; I Wayan Arya Krishnawan Firdaus
Dentin Vol 8, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v8i2.13113

Abstract

ABSTRACTBackground: Karamunting leaf have been used among community as traditional medication. Karamunting leaf have many properties because they contain secondary metabolite compounds such as flavonoids, triterpenoids, phenols, saponins and tannins. Administration as medicine is usually through oral. Oral administration of karamunting leaf in high dosage is considered to damage kidney microscopically. In vivo toxicity testing can be done to determine the toxicity effects of caramunting leaf extract at doses 600, 1200, 2400 mg/kg body weight before being tested on humans. Purpose: This study was conducted to determine whether karamunting leaf extract is toxic to the kidneys of Wistar rats subchronically with the parameters ureum and creatinine. Methods: The Rhodomyrtus Tomentosa (Aiton) Hassk. leaf were extracted using 96% ethanol and then given to male Wistar strain (Rattus norvegicus) with a 600, 1200, and 2400 mg/kg/body weight two times a day for 28 days. Rat blood was taken to check the levels of urea and creatinine. Result: The kidney ureum levels of Wistar rats in all treatment groups were still normal and did not exceed the normal range of ureum (10-50 mg/dL) while creatinine levels in all treatment groups were potentially toxic because they exceeded normal limits (0.578-1.128 mg/dL). Conclusion: The parameters of ureum and creatinine levels are not toxic because both can reduce the average value of both levels although some decrease significantly and some do not.Keywords : Creatinine, Excretion, Karamunting leaf, Kidney, Toxicity, Ureum ABSTRAKLatar Belakang: Daun karamunting telah digunakan oleh masyarakat sebagai obat tradisional. Daun karamunting banyak memiliki khasiat karena memiliki kandungan senyawa metabolit sekunder seperti flavonoid, triterpenoid, fenol, saponin dan tanin. Pemberiannya sebagai obat biasanya melalui oral. Pemberian daun ini secara oral dengan dosis tinggi diduga dapat merusak ginjal secara mikroskopis. Pengujian toksisitas secara in vivo dapat dilakukan untuk mengetahui efek toksisitas ekstrak daun karamunting pada dosis 600, 1200, 2400 mg/kg BB sebelum diujikan pada manusia. Tujuan: Penelitian ini dilakukan untuk mengetahui apakah ekstrak daun karamunting bersifat toksik terhadap ginjal tikus Wistar secara subkronik dengan parameter ureum dan kreatinin. Metode: Daun Rhodomyrtus Tomentosa (Aiton) Hassk. diekstraksi menggunakan etanol 96% dan kemudian diberikan pada tikus jantan galur Wistar (Rattus norvegicus) dengan dosis 600, 1200, dan 2400 mg/kg BB dua kali sehari selama 28 hari. Darah tikus diambil untuk memeriksa kadar urea dan kreatinin. Hasil: Kadar ureum ginjal tikus Wistar pada semua kelompok perlakuan masih normal dan tidak melebihi kisaran normal ureum (10-50 mg/dL), dan kadar kreatinin pada semua kelompok perlakuan juga normal karena tidak melebihi batas normal (0,578-1,128 mg/dL). Kesimpulan: Parameter kadar ureum dan kreatinin tidak toksik karena keduanya dapat menurunkan nilai rata-rata dari kedua kadar walaupun ada yang turun secara signifikan dan ada     yang tidak. Kata kunci: Ekskresi, Ekstrak Daun Karamunting, Ginjal, Kreatinin, Toksisitas, Ureum
PENGARUH PERENDAMAN AIR PDAM TERHADAP KEKERASAN ENAMEL GIGI PASKA HOME BLEACHING KARBAMID PEROKSIDA 20% Aqshall Ilham Safatullah; Agung Satria Wardhana; Sherli Diana; Beta Widya Oktiani; Renie Kumala Dewi
Dentin Vol 8, No 1 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v8i1.12194

Abstract

Background: One of the treatments to overcome the problem of discolored teeth is to do tooth whitening or bleaching. The tooth whitening agent that is often used is carbamide peroxide which is applied directly to the tooth enamel surface. Several factors that can affect tooth enamel are the degree of acidity or potential hydrogen (pH), acid concentration, dissolving time and the presence of calcium-like ions. Communities in Banjarmasin City still frequently use PDAM water for consumption and for their daily needs. Objective: To analyze the effect of immersing PDAM water and distilled water on the hardness of tooth enamel after the application of 20% carbamide peroxide. Methods: This study used a true experimental method with a posttest-only with control group design consisting of 4 treatment groups namely positive control PDAM water, negative control Aquatic water, group 1 carbamide peroxide 20% and PDAM water, and group 2 carbamide peroxide 20% and distilled water. Tooth enamel hardness was measured using a Vickers microhardness tester. Results: analysis of the One Way Anova test with Post-Hoc Bonferroni showed that there was a significant difference in violence in each group (p>0.05). Conclusion: There is an effect of PDAM water after application of 20% carbamide peroxide on the hardness of enamel on teeth.Keywords: Carbamide Peroxide 20%, Discolored, Enamel Hardness, PDAM
PERBANDINGAN EFEKTIVITAS DENTAL HEALTH EDUCATION MEDIA BONEKA BERGIGI DAN FLIPCHART TERHADAP PENGETAHUAN KESEHATAN GIGI DAN MULUT Az Zahra Khairinisa; R. Harry Dharmawan Setyawardhana; Galuh Dwita Sari; Irnamanda D.H.; Beta Widya Oktiani
Dentin Vol 9, No 2 (2025)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v9i2.17743

Abstract

ABSTRACTBackground: Based on the 2023 Indonesian Health Survey, the prevalence of dental caries in children aged 5–9 years reached 49.9%, while in South Kalimantan it was 43.9%. One of the main causes is the lack of children's knowledge about dental health. Educational interventions using appropriate media are very important to increase thatawareness. Purpose: To analyze the comparison of the effectiveness of Dental Health Education using tooth puppet media and flipchart media. Method: A quasi-experimental study with a nonequivalent pretest-posttest control group design involving 58 students aged 8–9 years at SDN Telaga Biru 1 Banjarmasin. The students were divided into two groups, each consisting of 29 students. The first group received education using flipchart media, the second group used tooth puppet media. The measurement was conducted using an 8-item questionnaire with the Guttman scale and analyzed using the Wilcoxon test and Mann- Whitney test. Result: In the flipchart group, 75.9% of students had high knowledge before the intervention and increased to 96.6% after the intervention. In the tooth puppet group, high knowledge increased from 79.3% to 100%. The Wilcoxon test showed a significant increase in knowledge in both groups. The Mann-Whitney test showed that the tooth puppet group had higher effectiveness compared to the flipchart, with a mean rank of 37.76 vs 21.24 (p = 0.000). Conclusion: Both educational media are effective in increasing students' knowledge about dental and oral health. Tooth puppet media is more recommended as the main choice in children's dental health education.Keywords: dental health education, flipchart, tooth puppet ABSTRAKLatar Belakang: Berdasarkan Survei Kesehatan Indonesia tahun 2023, prevalensi karies gigi pada anak usia 5–9 tahun mencapai 49,9%, sementara di Kalimantan Selatan sebesar 43,9%. Salah satu penyebab utamanya adalah rendahnya pengetahuan anak tentang kesehatan gigi. Intervensi edukatif menggunakan media yang sesuai sangat penting untuk meningkatkan kesadaran tersebut. Tujuan: Penelitian ini bertujuan untuk menganalisis perbandingan efektivitas Dental Health Education menggunakan media boneka bergigi dan media flipchart. Metode: Penelitian ini merupakan studi kuasi-eksperimental dengan desain nonequivalent pretest-posttest control group yang melibatkan 58 siswa usia 8–9 tahun di SDN Telaga Biru 1 Banjarmasin. Siswa dibagi menjadi dua kelompok masing-masing berjumlah 29 orang. Kelompok pertama diberikan edukasi menggunakan media flipchart, sedangkan kelompok kedua menggunakan media boneka bergigi. Pengukuran dilakukan dengan kuesioner 8 item menggunakan skala Guttman, dianalisis dengan uji Wilcoxon dan uji Mann-Whitney. Hasil: Pada kelompok flipchart, 75,9% siswa memiliki pengetahuan tinggi sebelum intervensi dan meningkat menjadi 96,6% setelah intervensi. Pada kelompok boneka bergigi, pengetahuan tinggi meningkat dari 79,3% menjadi 100%. Uji Wilcoxon menunjukkan peningkatan pengetahuan yang signifikan pada kedua kelompok (p = 0,000). Uji Mann- Whitney menunjukkan bahwa kelompok boneka bergigi memiliki efektivitas yang lebih tinggi dibanding flipchart, dengan mean rank 37,76 vs 21,24 (p = 0,000). Kesimpulan: Kedua media edukasi efektif dalam meningkatkan pengetahuan siswa tentang kesehatan gigi dan mulut. Media boneka bergigi lebih direkomendasikan sebagai pilihan utama dalam edukasi kesehatan gigi anak.Kata kunci : boneka bergigi, edukasi kesehatan gigi, flipchart