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All Journal Indonesian Journal of Cancer Chemoprevention Global Medical and Health Communication Biology, Medicine, & Natural Product Chemistry Smart Medical Journal Jurnal Kesehatan Vokasional Majalah Sainstekes Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Jurnal Ners Science Midwifery Medicra (Journal of Medical Laboratory Science/Technology) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Junior Medical Journal Eduvest - Journal of Universal Studies Advance Sustainable Science, Engineering and Technology (ASSET)

Nunung Ainur Rahmah

Faculty Of Medicine, Universitas YARSI

Author-ID : 3262454

Religion Aerospace Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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In Vivo Study of Telang Cream on Interleukin (IL)-6, Epidermal Growth Factor (EGF), and Wound Reepithelialization Pratiwi, Nike; Irwandi, Nurmayani; Hadi, Restu Syamsul; Thamrin, Nabila Pyrenina; Damayanti, Ndaru Andri; Juniarti, Juniarti; Rahmah, Nunung Ainur
Jurnal Kesehatan Vokasional Vol 10, No 2 (2025): May
Publisher : Sekolah Vokasi Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkesvo.106084

Background: Povidone iodine is widely used in wound healing, but it can cause irritation and cellular toxicity. Clitoria ternatea L. has the potential to contain compounds such as rutin, quercetin 3-O-rhamnoside, ternatin, and anthocyanins as natural alternatives in wound healing. In this study, the extract used contains anthocyanins.Objective: The study aimed to evaluate the effects of Clitoria ternatea L. extract cream on the expression of Interleukin-6, Epidermal Growth Factor, and re-epithelialization in Sprague Dawley rat incision wounds.Methods: An in-vivo study with a post-test only control design was conducted on five treatment groups, including a control group without wounds (healthy), povidone iodine, and Clitoria ternatea L. extract cream (5%, 10%, 15%). IL-6 and EGF were analyzed using immunohistochemistry, while re-epithelialization was assessed using hematoxylin-eosin staining.Results: Clitoria ternatea L. extract increased IL-6 and EGF expression, with the highest expression at a 10% concentration. Re-epithelialization was faster in the treatment groups compared to both the positive and negative controls.Conclusion: The 10% Clitoria ternatea L. extract cream demonstrated efficacy comparable to povidone iodine in incision wound healing.

Pengaruh Daun Teh Hijau Terhadap Organ Tikus Galur Wistar Setelah Paparan Asap Rokok Juniarti, Juniarti; Rahmah, Nunung Ainur; Janah, Lulu Ah; Dinda, Salsabila Chyllia; Patrisha, Milaviza; Agustin, Rika Alivia; Susmiarsih, Tripanjiasih
Majalah Sainstekes Vol. 12 No. 1 (2025): JUNI 2025
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/ms.v12i1.3654

Paparan asap rokok dapat menimbulkan berbagai macam penyakit yang berujung pada kematian. Banyak penelitian mengenai dampak merokok aktif terhadap kesehatan dan efek toksik keseluruhan, tetapi efek perokok pasif terhadap kesehatan tidak sepenuhnya dipahami. Asap rokok mengandung radikal bebas yang menyebabkan peningkatan stres oksidatif dan kerusakan organ. Salah satu bahan herbal, yaitu ekstrak daun teh hijau dapat menangani stress oksidatif sebab memiliki aktivitas antioksidan. Tujuan penelitian ini mengetahui pengaruh daun teh hijau terhadap kerusakan organ paru, hepar, dan ginjal akibat paparan pasif asap rokok dengan menggunakan model tikus jantan galur Wistar.Jenis penelitian adalah eksperimen. Sampel berupa tikus putih (Rattus norvegicus) galur Wistar selama 30 hari diberi paparan pasif asap rokok kretek tanpa filter dengan dosis 1 batang sehari dan ekstrak methanol daun teh hijau dengan dosis 100mg/kgBB. Setelah dilakukan pembedahan organ paru, hepar, dan ginjal, kemudian dilakukan pemeriksaan histopatologi dengan pewarnaan Hematoksilin-Eosin. Data diuji secara statistik mengunakan uji Wilcoxon. Hasil penelitian menunjukkan paparan pasif asap rokok pada tikus menyebabkan kerusakan pada organ bermakna secara statistik, pada paru (113,93%, p=0,000), hepar (59%, p=0,003), dan ginjal (89,82%, p=0,001). Pemberian ekstrak daun teh hijau pada tikus yang diberikan paparan pasif asap rokok dapat menurunkan kerusakan organ akibat paparan pasif asap rokok pada paru sebesar (49,04%, p=0,001), hepar sebesar (10,94%, p=0,132), dan ginjal sebesar (40,38%, p=0,003). Disimpulkan bahwa ekstrak daun teh hijau dapat memperbaiki kerusakan organ paru, hepar, dan ginjal akibat paparan pasif asap rokok.

Optimizing Image Preprocessing for AI-Driven Cervical Cancer Diagnosis Chandra Prasetyo Utomo; Neng Suhaeni; Nashuha Insani; Elan Suherlan; Nunung Ainur Rahmah; Ahmad Rusdan Utomo; Indra Kusuma; Muhamad Fathurachman; Dewa Nyoman Murti Adyaksa
Advance Sustainable Science Engineering and Technology Vol. 7 No. 1 (2025): November-January
Publisher : Science and Technology Research Centre Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/asset.v7i1.1128

Cervical cancer ranks among the top causes of cancer-related deaths in women globally. Early detection is vital for improving patient survival rates. The multiclass classification of cervical cell images presents challenges primarily due to the notable variations in cell sizes across different classes. Conventional AI methods for diagnosing cervical cancer often rely on image-resizing techniques that overlook crucial features like relative cell dimensions, which impairs the models' ability to distinguish between classes effectively. This paper presents a novel AI-driven approach that employs constant padding to maintain the natural size differences among cells. Our method utilizes deep learning for both feature extraction and multiclass classification. We assessed the method using the publicly accessible SIPaKMeD dataset. Experimental findings indicate that our approach surpasses traditional image-resizing methods, especially in classes that are more challenging to predict. This strategy highlights AI's potential to improve cervical cancer diagnosis, offering a more precise and dependable tool for early detection. A reliable and precise AI model for diagnosing cervical cancer is crucial for promoting widespread screening and ensuring timely and effective treatment, which can ultimately lower mortality rates. By aiding early and accurate diagnosis, this approach aligns with global health efforts to alleviate the burden of cancer and other diseases, especially in areas with limited access to advanced healthcare services facilities.

Faktor Risiko Kematian Pasien Covid-19 Periode September 2021 - 2022 di RS Yarsi dengan Komorbid Diabetes Melitus Serta Tinjauannya Menurut Pandangan Islam Putra Pangraizan, Farel; Mukhtar, Diniwati; Ainur Rahmah, Nunung; Ma'sum, Ali
Junior Medical Journal Vol. 3 No. 3 (2025): Maret 2025
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v3i3.4409

KATA KUNCI COVID-19, Diabetes Melitus, Komorbid, Kematian, Faktor Risiko ABSTRAK Penelitian ini dilakukan untuk mengetahui fakor resiko kematian pasien covid 19 periode september 2021-2022 di RS yarsi dengan komorbid diabetes melitus serta tinjauannya menurut pandangan islam. Penelitian ini menggunakan metode kuantitatif dengan desain penelitian kohort retrospektif. Sampel penelitian diambil secara total sampling. Data dikumpulkan melalui data sekunder menggunakan data rekam medis. Pada penelitian ini terdapat 10 Sampel. Analisis dilakukan menggunakan uji Chi Square: Hasil analisis menunjukkan tidak terdapat hubungan yang signifikan antara usia dan jenis kelamin terhadap kematian pasien covid-19 dengaan komorbid diabetes melitus dan komorbid lain karena nilai signifikansi tersebut memiliki nilai yang lebih besar dari 0,05, sehingga H0 diterima.Dalam pandangan islam, kematian dan penyakit dapat dibagi menjadi dua yaitu fisik dan non-fisik. Dalam kasus penelitian ini covid-19 sendiri masuk kedalam penyakit medis atau dalam pandangan islam masuk kedalam penyakit fisik yaitu penyakit badan, penyakit yang tampak dan dapat kita rasakan. KEYWORDS COVID-19, Geriatric, Comorbid, Death, Factor Risks ABSTRACT This research was conducted to determine the risk factors for death of Covid 19 patients for the period September 2021-2022 at Yarsi Hospital with comorbid diabetes mellitus and its review according to Islamic views. This research uses quantitative methods with a retrospective cohort research design. The research sample was taken by total sampling. Data was collected through secondary data using medical record data. In this study there were 10 samples. The analysis was carried out using the Chi Square test: The results of the analysis showed that there was no significant relationship between age and gender on the death of Covid-19 patients with comorbid diabetes mellitus and other comorbidities because the significance value had a value greater than 0.05, so H0 was accepted .In the Islamic view, death and disease can be divided into two, namely physical and non-physical. In the case of this research, Covid-19 itself is a medical disease or in the Islamic view it is a physical disease, namely a bodily disease, a disease that we can see and feel.

Faktor Risiko Kematian Pasien Covid-19 Periode September 2021 - 2022 di RS YARSI dengan Komorbid Hipertensi serta Tinjauannya Menurut Pandangan Islam Kiagus Raihan, Kiagus Raihan; Dr. dr. Hj. Diniwati Mukhtar, M. Kes., AIFM; Dr. dr. Hj. Nunung Ainur Rahmah, Sp.PA; Toto Heriyanto, S.Pd.I., M.Ag
Junior Medical Journal Vol. 3 No. 5 (2025): September 2025
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v3i5.4586

Pendahuluan: COVID-19 adalah penyakit menular, memiliki penularan melalui droplet dan kontak langsung. Pasien COVID-19 yang memiliki penyakit penyerta menunjukkan prognosis yang lebih buruk. Hipertensi, atau tekanan darah tinggi, telah diidentifikasi sebagai komorbiditas COVID-19, yang berarti bahwa individu dengan hipertensi memiliki risiko yang lebih tinggi terhadap penyakit parah atau komplikasi akibat virus tersebut. Oleh karena itu, penting untuk mengetahui korelasi antara riwayat diabetes melitus dan hipertensi dengan lama rawat inap pasien COVID-19 dari pandangan kedokteran dan Islam. Metodologi: Penelitian menggunakan metode kuantitatif dengan desain penelitian kohort retrospektif. Sampel penelitian diambil secara total sampling. Data dikumpulkan melalui data sekunder menggunakan data rekam medis dari RS YARSI selama periode September 2021 - 2022. Hasil: Penelitian ini menunjukkan bahwa dari 48 pasien COVID-19 yang memasuki kriteria untuk diteliti, 34 pasien (71%) memiliki komorbid hipertensi, dan 14 pasien (29%) tidak memiliki komorbid hipertensi. Dari pasien dengan komorbid hipertensi, sebanyak 30 pasien (63%) meninggal dunia. Analisis bivariat dengan uji Chi Square menunjukkan nilai signifikansi (Sig.) sebesar 0.008, yang lebih kecil dari 0.05, menunjukkan adanya hubungan yang signifikan antara hipertensi dan kematian pasien COVID-19 Simpulan: Terdapat hubungan antara pasien Covid-19 yang memiliki hipertensi dengan pasien yang meninggal dunia pada Rumah Sakit YARSI periode September 2021 sampai dengan September 2022

Pengaruh Ekstrak Kayu Bajakah Merah (Sphatolobus Littoralis) terhadap Kadar Protein Pro-Apoptosis P53 pada Sel MCF-7 Raka Auriza Fathaya; Harliansyah Harliansyah; Ahmad Randy; Pendrianto Pendrianto; Nunung Ainur Rahmah
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.54282

Kanker payudara merupakan jenis kanker dengan angka kejadian dan kematian tertinggi pada wanita di dunia. Salah satu model sel kanker payudara yang banyak digunakan dalam penelitian adalah sel MCF-7 yang bersifat sensitif terhadap estrogen. Protein p53 berperan penting sebagai supresor tumor melalui pengaturan siklus sel dan induksi apoptosis. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak kayu bajakah merah (Spatholobus littoralis) terhadap kadar protein pro-apoptosis p53 pada sel kanker payudara MCF-7. Penelitian ini merupakan penelitian eksperimental dengan rancangan true-experimental pretest–posttest control group design. Sel MCF-7 dibagi menjadi empat kelompok, yaitu blanko, kontrol negatif, kontrol positif (tamoxifen 4,81 ppm), dan kelompok perlakuan ekstrak kayu bajakah merah dengan konsentrasi IC₅₀ sebesar 116,4 ppm. Sel diinkubasi selama 72 jam pada suhu 37°C dengan 5% CO₂. Kadar protein p53 diukur menggunakan metode ELISA. Hasil penelitian menunjukkan bahwa pemberian ekstrak kayu bajakah merah meningkatkan kadar protein p53 secara signifikan dibandingkan kelompok kontrol, meskipun masih lebih rendah dibandingkan tamoxifen. Temuan ini menunjukkan bahwa ekstrak kayu bajakah merah berpotensi sebagai agen antikanker melalui aktivasi jalur p53 dan sejalan dengan prinsip pengobatan herbal dalam Islam.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkesvo.106084

Potential of Jatropha Multifida L.- Placenta - Carboxymehyl Chitosan (CMC) Formulation as Regenerative Therapy for Burn Wounds Mellyna Mellyna; Juniarti Juniarti; Nunung Ainur Rahmah
Eduvest - Journal of Universal Studies Vol. 6 No. 4 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i4.52546

Second-degree burns are tissue injuries that often cause complications and require a long healing time. Previous studies have reported that natural ingredients such as Jatropha multifida L., placenta extract, and Carboxymethyl Chitosan (JM-P-CMC) have the potential to accelerate tissue regeneration, but no combined studies have been conducted on the three. The study aimed to evaluate the effect of the Jatropha multifida L.-Plasenta-CMC combination formulation on the number of fibroblasts as an indicator of tissue regeneration in second-degree burns. This experimental study used a post-test only control group design with 24 male Sprague dawley rats (200–250 g) induced burns on the back using a hot metal plate, then divided into four groups: control (Bioplacenton ® ), JM5%-P-CMC, JM10%-P-CMC, and JM15%-P-CMC. Topical treatment was carried out twice a day for 14 days. Data collection was carried out on days 5, 9, and 14, followed by histological analysis of skin tissue with Hematoxylin Eosin staining to count the number of fibroblasts. The results of the Kruskal-Wallis and Mann-Whitney tests showed a significant increase in the number of fibroblasts in all treatment groups compared to the control, with the highest results in the JM15%-P-CMC group. This study concluded that the combination was effective in enhancing tissue regeneration and has the potential to be developed as an innovative topical therapy based on natural ingredients.

Pengaruh Efek Ekstrak Kayu Bajakah Merah (Sphatolobus littoralis) Terhadap Kadar Protein mTOR pada Sel Kanker Payudara MCF-7 Ratu Salia Siskowati; Harliansyah Harliansyah; Nunung Ainur Rahmah; Ahmad Randy; Pendrianto Pendrianto
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.54258

Abstrak Salah satu penyakit yang paling umum terjadi pada wanita adalah kanker payudara, yang terkait dengan pembelahan sel yang tidak terkendali melalui jalur sinyal mTORC. Studi ini bertujuan untuk menentukan bagaimana ekstrak Kayu Bajakah Merah (Spatholobus littoralis) mempengaruhi ekspresi protein mTORC secara in vitro pada sel kanker payudara MCF-7. Penelitian menggunakan desain true experimental dengan post-test only control group, melibatkan enam kelompok perlakuan, termasuk kontrol negatif, kontrol positif (Tamoxifen), dan perlakuan ekstrak Bajakah Merah pada konsentrasi IC₅ 72 jam. Sel dikultur, diolah, dan viabilitas sel diukur menggunakan CCK-8 untuk menentukan IC₅, sedangkan kadar protein mTORC dianalisis menggunakan ELISA. Hasil penelitian menunjukkan bahwa ekstrak Bajakah Merah menurunkan viabilitas sel secara dosis- dan waktu-dependen, dengan IC₅ terendah pada inkubasi 72 jam. Kadar mTORC meningkat signifikan pada kelompok perlakuan ekstrak dibanding kontrol negatif, menunjukkan pengaruh ekstrak terhadap jalur pensinyalan mTORC. Meskipun efek sitotoksik masih lebih rendah dibanding Tamoxifen, ekstrak kayu Bajakah Merah memiliki potensi sebagai agen kemopreventif berbasis bahan alam.. Kata Kunci: kanker payudara, MCF-7, ekstrak kayu Bajakah Merah, mTORC, sitotoksik, kemoprevensi. Abstract One of the most prevalent diseases in women is breast cancer, which is linked to unchecked cell division via the mTORC signaling pathway. This study sought to determine how Red Bajakah Wood (Spatholobus littoralis) extract affected the in vitro expression of the mTORC protein in MCF-7 breast cancer cells. A true experimental design with post-test only control group was employed, including six treatment groups: negative control, positive control (Tamoxifen), and Red Bajakah Wood extract at IC₅₀ 72-hour concentration. Cells were cultured, treated, and viability assessed using CCK-8 to determine IC₅₀, while mTORC protein levels were measured via ELISA. Results showed that Red Bajakah Wood extract reduced cell viability in a dose- and time-dependent manner, with the lowest IC₅₀ at 72 hours incubation. mTORC levels increased significantly in extract-treated cells compared to negative control, indicating the extract’s effect on the mTORC signaling pathway. Although its cytotoxicity was lower than Tamoxifen, Red Bajakah Wood extract demonstrated potential as a natural-based chemopreventive agent.. Keywords: breast cancer, MCF-7, Red Bajakah Wood extract, mTORC, cytotoxicity, chemoprevention.

The Role of Umbilical Cord–Derived Mesenchymal Stem Cell Secretome in Regulating Oxidative Stress and Inflammation in Skin Cells Yuniar, Fanni; Purwaningsih, Endang; Rahmah, Nunung Ainur; Lilis, Nenden
Smart Medical Journal Vol 9, No 1 (2026): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v9i1.115685

Introduction: Oxidative stress and inflammation are tightly interconnected processes that drive skin aging, impaired wound healing, and inflammatory skin disorders. Excessive reactive oxygen species (ROS) disrupt skin cell homeostasis, promote cellular senescence, and sustain inflammatory signaling, ultimately compromising skin regeneration. Umbilical cord–derived mesenchymal stem cell (UC-MSC) secretome has recently emerged as a promising cell-free therapeutic approach to modulate these pathological mechanisms.Methods: A narrative literature review was conducted using PubMed, Scopus, ScienceDirect, and Google Scholar to identify studies investigating the role of UC-MSC secretome in regulating oxidative stress and inflammation in skin cells. Search terms included combinations of “UC-MSC secretome,” “extracellular vesicles,” “exosomes,” “oxidative stress,” “inflammation,” “keratinocytes,” “fibroblasts,” and “wound healing.” studies relevant to skin biology were included based on biological relevance and mechanistic insight rather than strict methodological filtering.Results: The UC-MSC secretome, composed of soluble factors and extracellular vesicles enriched with bioactive proteins, cytokines, antioxidant enzymes, and regulatory microRNAs, consistently demonstrates antioxidant and anti-inflammatory effects in keratinocytes, fibroblasts, and melanocytes. Mechanistically, it reduces intracellular and mitochondrial ROS, activates endogenous antioxidant pathways such as Nrf2 and FOXO, preserves mitochondrial function, and NF-κB and MAPK. In vitro and in vivo studies show attenuation of UV-induced photoaging, enhanced wound healing, and protection of melanocytes from oxidative and immune-mediated damage.Conclusion: Current evidence supports UC-MSC secretome as a potent regulator of oxidative stress and inflammation in skin cells. Its cell-free nature offers advantages in safety, scalability, and therapeutic flexibility, highlighting strong translational potential for dermatology and regenerative skin medicine.

Co-Authors Aan Royhan Abdussalam, Moch Adilah Ulinnuha Agung Novianto, Agung Agustin, Rika Alivia Ahmad Randy Ahmad Rusdan Utomo Ahmad Rusdan Utomo Al Ichsan Alfia, Nurul Ari Fahrial Syam Arifandi, Firman Arrahmani, Betharie Cendera Batubara, Lilian Bethy Suryawati Hernowo Chandra Prasetyo Utomo Citra Fitri Agustina Damayanti, Ndaru Andri Darmawan Kartono David Handojo Muljono Dewa Nyoman Murti Adyaksa Dewa Nyoman Murti Adyaksa Diah Rini Handjari Diah Rini Handjari Dianti, Sry Vhina Dinda, Salsabila Chyllia Diniwati Mukhtar Dr. dr. Hj. Diniwati Mukhtar, M. Kes., AIFM Elan Suherlan Elan Suherlan Endang Purwaningsih Endy Muhammad Astiwara Ening Krisnuhoni Fachry Abda El Rahman Firman Arifandi Firman Arifandi Fitria Nur Ain Fransiscus D. Suyatna Hanna Sari Widya Kusuma, Hanna Sari Widya Harliansyah Harliansyah Harliansyah Harliansyah Harliansyah INDRA KUSUMA Indra Kusuma Indranita, Lusy Irfan Syarif, Irfan Irwandi, Nurmayani Janah, Lulu Ah Joedo Prihartono Juniarti Juniarti . Juniarti Juniarti Kiagus Raihan, Kiagus Raihan Kuslestari Kuslestari Ma'sum, Ali Mellyna Mellyna Mpu Kanoko Muhamad Fathurachman Muhamad Fathurachman Muhammad Achmad Yani Muhammad Arsyad Muhammad Kholik Sanaba Mustofa, Muhammad Samsul Nafik, Said Nashuha Insani Nashuha Insani Nenden Lilis Aisyah Neng Suhaeni Neng Suhaeni Patrisha, Milaviza Pendrianto Pendrianto Pendrianto Pendrianto, Pendrianto prastina sari, Putri Agnia Pratiwi, Nike Primariadewi Rustamadji Putra Pangraizan, Farel Raka Auriza Fathaya Ratu Salia Siskowati Restu Syamsul Hadi Riani, Siti Nur Rostiana, Ajeng Nita Saffa Hasanah Samuel Johny Haryono Sri Utami Susi Endrini Susmiarsih, Tripanjiasih Syafruddin A. R. Lelosutan Taslim, Siti Ghadira Inayah Thamrin, Nabila Pyrenina Toto Heriyanto, S.Pd.I., M.Ag Triana Intan Sari Ulisyafitri, Atikah Vera Yuwono WAHYU WIDOWATI Wiji Purnamasari, Yulia Wirasmi Marwoto Wirasmi Marwoto Yulia Suciati Yuniar, Fanni Yusnidar, Amirah

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